Published in Circ Res on July 20, 2006
Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules. Proc Natl Acad Sci U S A (2010) 1.70
Regulation of proteasome activity in health and disease. Biochim Biophys Acta (2013) 1.52
Oxidative stress-mediated regulation of proteasome complexes. Mol Cell Proteomics (2011) 1.50
Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies. Circulation (2010) 1.49
Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload. J Mol Cell Cardiol (2015) 1.41
Enhancement of proteasome function by PA28α overexpression protects against oxidative stress. FASEB J (2010) 1.40
Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy. Circ Res (2010) 1.34
Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics (2008) 1.29
Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice. Circ Res (2010) 1.24
Protein quality control and degradation in cardiomyocytes. J Mol Cell Cardiol (2008) 1.22
Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach. Mol Cell Proteomics (2008) 1.19
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. Cardiovasc Res (2009) 1.18
Ischemic preconditioning-induced cardioprotection is lost in mice with immunoproteasome subunit low molecular mass polypeptide-2 deficiency. FASEB J (2008) 1.14
Proteasome functional insufficiency in cardiac pathogenesis. Am J Physiol Heart Circ Physiol (2011) 1.11
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A (2011) 1.09
Posttranslational modification and quality control. Circ Res (2013) 1.06
Protein quality control disruption by PKCβII in heart failure; rescue by the selective PKCβII inhibitor, βIIV5-3. PLoS One (2012) 1.05
AIP-1 ameliorates beta-amyloid peptide toxicity in a Caenorhabditis elegans Alzheimer's disease model. Hum Mol Genet (2009) 1.01
The role of the proteasome in heart disease. Biochim Biophys Acta (2010) 0.99
The ubiquitin proteasome system in human cardiomyopathies and heart failure. Am J Physiol Heart Circ Physiol (2013) 0.99
Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Mol Cell Proteomics (2013) 0.98
Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell death. J Biol Chem (2011) 0.95
Osmotic stress inhibits proteasome by p38 MAPK-dependent phosphorylation. J Biol Chem (2010) 0.93
The ubiquitin-proteasome system and cardiovascular disease. Prog Mol Biol Transl Sci (2012) 0.93
Understanding proteasome assembly and regulation: importance to cardiovascular medicine. Trends Cardiovasc Med (2008) 0.92
Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human. Mol Cell Proteomics (2013) 0.91
The ubiquitin proteasome system and myocardial ischemia. Am J Physiol Heart Circ Physiol (2012) 0.90
Genetics of proteasome diseases. Scientifica (Cairo) (2013) 0.90
Two-dimensional electrophoresis-based characterization of post-translational modifications of mammalian 20S proteasome complexes. Proteomics (2008) 0.89
The cardiac 26S proteasome: regulating the regulator. Circ Res (2006) 0.87
Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics. Am J Physiol Heart Circ Physiol (2012) 0.87
Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag. Mol Cell Proteomics (2012) 0.87
Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies. Antioxid Redox Signal (2014) 0.85
Linking transcriptional changes over time in stimulated dendritic cells to identify gene networks activated during the innate immune response. PLoS Comput Biol (2013) 0.83
Pregnancy is associated with decreased cardiac proteasome activity and oxidative stress in mice. PLoS One (2012) 0.83
Regulating the ubiquitin/proteasome pathway via cAMP-signaling: neuroprotective potential. Cell Biochem Biophys (2013) 0.81
Proteome dynamics and proteome function of cardiac 19S proteasomes. Mol Cell Proteomics (2011) 0.81
Impaired assembly and post-translational regulation of 26S proteasome in human end-stage heart failure. Circ Heart Fail (2013) 0.81
Cardioproteomics: advancing the discovery of signaling mechanisms involved in cardiovascular diseases. Am J Cardiovasc Dis (2011) 0.80
A novel spectral library workflow to enhance protein identifications. J Proteomics (2013) 0.80
Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependent manner. J Mol Cell Cardiol (2014) 0.78
Characterizing the dynamics of proteasome complexes by proteomics approaches. Antioxid Redox Signal (2014) 0.77
Tuning the proteasome to brighten the end of the journey. Am J Physiol Cell Physiol (2016) 0.76
Solution structure and Rpn1 interaction of the UBL domain of human RNA polymerase II C-terminal domain phosphatase. PLoS One (2013) 0.76
Reversible phosphorylation of the 26S proteasome. Protein Cell (2017) 0.75
Activation of β-adrenergic receptors is required for elevated α1A-adrenoreceptors expression and signaling in mesenchymal stromal cells. Sci Rep (2016) 0.75
Priming the proteasome by protein kinase G: a novel cardioprotective mechanism of sildenafil. Future Cardiol (2015) 0.75
Precise assembly and regulation of 26S proteasome and correlation between proteasome dysfunction and neurodegenerative diseases. BMB Rep (2016) 0.75
Proteomic insights into cardiac cell death and survival. Proteomics Clin Appl (2008) 0.75
The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol (2007) 10.24
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab (2007) 5.04
Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles. J Proteome Res (2009) 3.77
A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science (2007) 3.73
Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation. Proc Natl Acad Sci U S A (2005) 3.30
Role of the mitochondrial permeability transition in myocardial disease. Circ Res (2003) 3.26
Metastatic patterns of cancers: results from a large autopsy study. Arch Pathol Lab Med (2008) 3.19
Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice. PLoS Pathog (2009) 3.05
Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol (2002) 3.01
NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. J Clin Invest (2015) 2.93
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes. Proc Natl Acad Sci U S A (2005) 2.85
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating. Proc Natl Acad Sci U S A (2008) 2.82
A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria. Science (2006) 2.71
From Mallory to Mallory-Denk bodies: what, how and why? Exp Cell Res (2007) 2.61
PNPASE regulates RNA import into mitochondria. Cell (2010) 2.54
BioJS: an open source JavaScript framework for biological data visualization. Bioinformatics (2013) 2.53
Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria. Circ Res (2003) 2.52
The iron chelator deferasirox protects mice from mucormycosis through iron starvation. J Clin Invest (2007) 2.48
A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation. J Clin Invest (2006) 2.39
Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J Clin Invest (2006) 2.23
Mapping the murine cardiac 26S proteasome complexes. Circ Res (2006) 2.17
Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice. Hepatology (2014) 2.17
Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis. MBio (2012) 2.15
Emerging role of epigenetics in the actions of alcohol. Alcohol Clin Exp Res (2008) 2.14
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest (2009) 2.06
Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function? J Mol Cell Cardiol (2009) 2.02
Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage. Gastroenterology (2010) 2.00
Fungi and inflammatory bowel diseases: Alterations of composition and diversity. Scand J Gastroenterol (2008) 1.89
Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun (2003) 1.78
Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells. J Neurosci (2005) 1.75
Steatohepatitis induced by intragastric overfeeding in mice. Hepatology (2005) 1.73
Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation (2013) 1.69
Oxidative stress and regulation of anti-oxidant enzymes in cytochrome P4502E1 transgenic mouse model of non-alcoholic fatty liver. J Gastroenterol Hepatol (2010) 1.68
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation (2011) 1.66
Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res (2006) 1.62
S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory. Hepatology (2008) 1.60
Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation. Channels (Austin) (2009) 1.57
Electrospray ionization mass spectrometry and ion mobility analysis of the 20S proteasome complex. J Am Soc Mass Spectrom (2005) 1.53
Metabolic labeling reveals proteome dynamics of mouse mitochondria. Mol Cell Proteomics (2012) 1.53
Systematic characterization of the murine mitochondrial proteome using functionally validated cardiac mitochondria. Proteomics (2008) 1.51
Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition. Am J Physiol Heart Circ Physiol (2004) 1.51
Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis. Mol Cell Biol (2006) 1.49
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. Exp Mol Pathol (2008) 1.48
Malignant and benign mutations in familial cardiomyopathies: insights into mutations linked to complex cardiovascular phenotypes. J Mol Cell Cardiol (2010) 1.47
Sizing large proteins and protein complexes by electrospray ionization mass spectrometry and ion mobility. J Am Soc Mass Spectrom (2007) 1.46
Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs. Am J Physiol Gastrointest Liver Physiol (2005) 1.45
Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS. Mol Cell Proteomics (2002) 1.44
Cyclin-dependent kinase 2 signaling regulates myocardial ischemia/reperfusion injury. J Mol Cell Cardiol (2008) 1.44
A new function in translocation for the mitochondrial i-AAA protease Yme1: import of polynucleotide phosphorylase into the intermembrane space. Mol Cell Biol (2006) 1.44
Histologic evaluation and treatment outcome after sequential radiofrequency ablation and hepatic resection for primary and metastatic tumors. Am Surg (2002) 1.43
Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen. J Biol Chem (2003) 1.42
Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. Mol Cell Proteomics (2010) 1.41
Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice. Exp Mol Pathol (2008) 1.41
Mammalian proteasome subpopulations with distinct molecular compositions and proteolytic activities. Mol Cell Proteomics (2007) 1.41
Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK. J Hepatol (2011) 1.39
Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells. J Clin Invest (2013) 1.37
Gene expression patterns of the liver in response to alcohol: in vivo and in vitro models compared. Exp Mol Pathol (2006) 1.36
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J Clin Invest (2009) 1.36
Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy. Circ Res (2010) 1.34
Treatment with a farnesyltransferase inhibitor improves survival in mice with a Hutchinson-Gilford progeria syndrome mutation. Biochim Biophys Acta (2007) 1.33
Loss of ABCG1 results in chronic pulmonary inflammation. J Immunol (2008) 1.32
S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model. Hepatology (2009) 1.32
CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation. Exp Mol Pathol (2006) 1.31
Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes. J Cell Sci (2004) 1.31
SAMe prevents the up regulation of toll-like receptor signaling in Mallory-Denk body forming hepatocytes. Exp Mol Pathol (2010) 1.29
Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics (2008) 1.29
Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation. Mol Cell Proteomics (2010) 1.28
Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms. Exp Mol Pathol (2008) 1.27
Functional analysis of a troponin I (R145G) mutation associated with familial hypertrophic cardiomyopathy. J Biol Chem (2002) 1.27
Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage. Hepatology (2002) 1.27
Chronic ethanol feeding alters hepatocyte memory which is not altered by acute feeding. Alcohol Clin Exp Res (2009) 1.27
The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis. Mol Microbiol (2010) 1.27
Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma. Proc Natl Acad Sci U S A (2002) 1.26
Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy. Cardiovasc Res (2013) 1.25
The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats. Gastroenterology (2002) 1.24
Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide. Circ Res (2008) 1.24
A phagocytic cell line markedly improves survival of infected neutropenic mice. J Leukoc Biol (2005) 1.23
Different immunoaffinity fractionation strategies to characterize the human plasma proteome. J Proteome Res (2006) 1.23
The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production. Hepatology (2009) 1.21
2-DE with IPGs. Electrophoresis (2009) 1.20
Mallory body (cytokeratin aggresomes) formation is prevented in vitro by p38 inhibitor. Exp Mol Pathol (2006) 1.20
Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A. FASEB J (2004) 1.19
Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach. Mol Cell Proteomics (2008) 1.19