Published in Mol Microbiol on June 01, 2010
Pathogenesis of mucormycosis. Clin Infect Dis (2012) 2.14
Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial mucorales (Mucoromycotina). PLoS Genet (2014) 1.61
Recent advances in the treatment of mucormycosis. Curr Infect Dis Rep (2010) 1.31
Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides. PLoS Pathog (2011) 1.26
Risk factors for mortality in patients with mucormycosis. Med Mycol (2012) 1.13
Clinical spectrum and outcome of invasive filamentous fungal infections in children with Type 1 diabetes: North Indian experience. Clin Pediatr Endocrinol (2015) 1.07
CotH3 mediates fungal invasion of host cells during mucormycosis. J Clin Invest (2013) 1.04
Diabetic murine models for Acinetobacter baumannii infection. J Antimicrob Chemother (2012) 0.98
Combination therapy of murine mucormycosis or aspergillosis with iron chelation, polyenes, and echinocandins. Antimicrob Agents Chemother (2011) 0.93
Invasive mold infections: virulence and pathogenesis of mucorales. Int J Microbiol (2011) 0.88
An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans. Trends Microbiol (2013) 0.87
The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation. Fungal Genet Biol (2011) 0.86
Update on mucormycosis pathogenesis. Curr Opin Infect Dis (2013) 0.86
Conflicting interests in the pathogen-host tug of war: fungal micronutrient scavenging versus mammalian nutritional immunity. PLoS Pathog (2014) 0.86
The spectrum of fungi that infects humans. Cold Spring Harb Perspect Med (2014) 0.81
Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. PLoS Pathog (2015) 0.79
RNAi-Based Functional Genomics Identifies New Virulence Determinants in Mucormycosis. PLoS Pathog (2017) 0.77
Long-distance translocation of protein during morphogenesis of the fruiting body in the filamentous fungus, Agaricus bisporus. PLoS One (2011) 0.77
Metabolic engineering of Rhizopus oryzae for the production of platform chemicals. Appl Microbiol Biotechnol (2012) 0.77
The Role of Aquaporins in pH-Dependent Germination of Rhizopus delemar Spores. PLoS One (2016) 0.76
Iron starvation induces apoptosis in Rhizopus oryzae in vitro. Virulence (2015) 0.75
Host-iron assimilation: pathogenesis and novel therapies of mucormycosis. Mycoses (2014) 0.75
Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. J Clin Invest (2016) 0.75
Apophysomyces variabilis: draft genome sequence and comparison of predictive virulence determinants with other medically important Mucorales. BMC Genomics (2017) 0.75
Molecular mechanisms of mucormycosis-The bitter and the sweet. PLoS Pathog (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis (2005) 13.97
Zygomycetes in human disease. Clin Microbiol Rev (2000) 9.80
Construct design for efficient, effective and high-throughput gene silencing in plants. Plant J (2001) 7.73
Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients. Clin Infect Dis (2002) 6.99
Novel perspectives on mucormycosis: pathophysiology, presentation, and management. Clin Microbiol Rev (2005) 5.77
A permease-oxidase complex involved in high-affinity iron uptake in yeast. Science (1996) 4.60
Invasive zygomycosis in hematopoietic stem cell transplant recipients receiving voriconazole prophylaxis. Clin Infect Dis (2004) 3.20
Pathogenicity of Candida albicans auxotrophic mutants in experimental infections. Infect Immun (1991) 2.91
Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence. J Exp Med (2004) 2.90
Zygomycosis in the 1990s in a tertiary-care cancer center. Clin Infect Dis (2000) 2.78
A high-affinity iron permease essential for Candida albicans virulence. Science (2000) 2.68
The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae. J Biol Chem (1994) 2.64
Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis. Clin Infect Dis (2008) 2.63
Ectopic expression of URA3 can influence the virulence phenotypes and proteome of Candida albicans but can be overcome by targeted reintegration of URA3 at the RPS10 locus. Eukaryot Cell (2004) 2.63
Transport of haemin across the cytoplasmic membrane through a haemin-specific periplasmic binding-protein-dependent transport system in Yersinia enterocolitica. Mol Microbiol (1994) 2.59
Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob Agents Chemother (2005) 2.54
Altered expression of selectable marker URA3 in gene-disrupted Candida albicans strains complicates interpretation of virulence studies. Infect Immun (1998) 2.51
The iron chelator deferasirox protects mice from mucormycosis through iron starvation. J Clin Invest (2007) 2.48
Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies. J Clin Invest (1993) 2.45
Molecular and genetic analysis of URA5 transformants of Cryptococcus neoformans. Infect Immun (1992) 2.32
Improved outcome of zygomycosis in patients with hematological diseases? Leuk Lymphoma (2004) 2.20
Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication. PLoS Genet (2009) 2.15
Liposomal amphotericin B, and not amphotericin B deoxycholate, improves survival of diabetic mice infected with Rhizopus oryzae. Antimicrob Agents Chemother (2003) 2.01
Deferiprone iron chelation as a novel therapy for experimental mucormycosis. J Antimicrob Chemother (2006) 1.99
A mechanism of susceptibility to mucormycosis in diabetic ketoacidosis: transferrin and iron availability. Diabetes (1982) 1.99
The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infect Immun (2002) 1.91
The Aspergillus fumigatus siderophore biosynthetic gene sidA, encoding L-ornithine N5-oxygenase, is required for virulence. Infect Immun (2005) 1.84
Direct hemin transfer from IsdA to IsdC in the iron-regulated surface determinant (Isd) heme acquisition system of Staphylococcus aureus. J Biol Chem (2008) 1.72
RNA silencing as a tool for exploring gene function in ascomycete fungi. Fungal Genet Biol (2005) 1.67
A family of Candida cell surface haem-binding proteins involved in haemin and haemoglobin-iron utilization. Mol Microbiol (2004) 1.67
Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus. Infect Immun (2002) 1.65
Iron source preference and regulation of iron uptake in Cryptococcus neoformans. PLoS Pathog (2008) 1.65
Specific susceptibility to mucormycosis in murine diabetes and bronchoalveolar macrophage defense against Rhizopus. J Clin Invest (1984) 1.63
Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus. Infect Immun (1996) 1.60
Pathway for heme uptake from human methemoglobin by the iron-regulated surface determinants system of Staphylococcus aureus. J Biol Chem (2008) 1.59
Deferoxamine augments growth and pathogenicity of Rhizopus, while hydroxypyridinone chelators have no effect. Kidney Int (1994) 1.55
Siderophore-mediated iron uptake in Saccharomyces cerevisiae: the SIT1 gene encodes a ferrioxamine B permease that belongs to the major facilitator superfamily. Microbiology (1998) 1.45
Zygomycosis: reemergence of an old pathogen. Clin Infect Dis (2004) 1.43
Haemin uptake and use as an iron source by Candida albicans: role of CaHMX1-encoded haem oxygenase. Microbiology (2003) 1.40
Iron acquisition: a novel perspective on mucormycosis pathogenesis and treatment. Curr Opin Infect Dis (2008) 1.38
Iron uptake from ferrioxamine and from ferrirhizoferrin by germinating spores of Rhizopus microsporus. Biochem Pharmacol (1994) 1.35
Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity. Infect Immun (2005) 1.35
Reductive iron uptake by Candida albicans: role of copper, iron and the TUP1 regulator. Microbiology (2002) 1.31
Survival of Aspergillus fumigatus in serum involves removal of iron from transferrin: the role of siderophores. Infect Immun (2004) 1.28
The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centromere protein essential for chromosome transmission. Proc Natl Acad Sci U S A (2002) 1.26
A multicopper oxidase gene from Candida albicans: cloning, characterization and disruption. Microbiology (1999) 1.26
An endocytic mechanism for haemoglobin-iron acquisition in Candida albicans. Mol Microbiol (2008) 1.25
Iron acquisition from transferrin by Candida albicans depends on the reductive pathway. Infect Immun (2005) 1.22
Rhizoferrin: a complexone type siderophore of the Mucorales and entomophthorales (Zygomycetes). FEMS Microbiol Lett (1992) 1.18
Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene. FEMS Microbiol Lett (2004) 1.11
HtaA is an iron-regulated hemin binding protein involved in the utilization of heme iron in Corynebacterium diphtheriae. J Bacteriol (2009) 1.10
Heme oxygenase in Candida albicans is regulated by hemoglobin and is necessary for metabolism of exogenous heme and hemoglobin to alpha-biliverdin. J Biol Chem (2003) 1.09
The role of desferrioxamine in dialysis-associated mucormycosis: report of three cases and review of the literature. Clin Nephrol (1988) 1.04
In vivo analysis of Aspergillus fumigatus developmental gene expression determined by real-time reverse transcription-PCR. Infect Immun (2008) 1.04
Siderophore uptake by Candida albicans: effect of serum treatment and comparison with Saccharomyces cerevisiae. Yeast (2002) 1.02
Functional identification of high-affinity iron permeases from Fusarium graminearum. Fungal Genet Biol (2006) 0.92
Native and modified lactate dehydrogenase expression in a fumaric acid producing isolate Rhizopus oryzae 99-880. Curr Genet (2007) 0.89
Plasmids for expression of heterologous proteins in Rhizopus oryzae. Arch Microbiol (2006) 0.89
Homologous recombination and double-strand break repair in the transformation of Rhizopus oryzae. Mol Genet Genomics (2002) 0.88
Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase. Med Mycol (2004) 0.87
Induction of Rhizopus oryzae pyruvate decarboxylase genes. Curr Microbiol (2003) 0.85
Mucormycosis infection in dialysis patients. Ann Intern Med (1987) 0.79
Inhibition of non-homologous end joining and integration of DNA upon transformation of Rhizopus oryzae. Mol Genet Genomics (2005) 0.77
Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis (2009) 22.98
Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med (2002) 21.28
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis (2009) 18.19
Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis (2005) 8.77
Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med (2005) 8.39
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
Combating antimicrobial resistance: policy recommendations to save lives. Clin Infect Dis (2011) 5.58
Guidelines for treatment of candidiasis. Clin Infect Dis (2003) 5.55
Trends in antimicrobial drug development: implications for the future. Clin Infect Dis (2004) 5.23
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat Genet (2013) 4.48
A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients. Clin Infect Dis (2003) 4.29
Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog (2006) 3.58
Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. PLoS Biol (2007) 3.43
Empirical fluconazole versus placebo for intensive care unit patients: a randomized trial. Ann Intern Med (2008) 3.36
Metastatic patterns of cancers: results from a large autopsy study. Arch Pathol Lab Med (2008) 3.19
Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice. PLoS Pathog (2009) 3.05
Nosocomial fungal infections: epidemiology, diagnosis, and treatment. Med Mycol (2007) 3.02
Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol (2002) 3.01
NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. J Clin Invest (2015) 2.93
A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects. Clin Infect Dis (2003) 2.84
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines. J Natl Cancer Inst (2010) 2.79
Functional and structural diversity in the Als protein family of Candida albicans. J Biol Chem (2004) 2.77
Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis. Clin Infect Dis (2008) 2.63
From Mallory to Mallory-Denk bodies: what, how and why? Exp Cell Res (2007) 2.61
PNPASE regulates RNA import into mitochondria. Cell (2010) 2.54
Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob Agents Chemother (2005) 2.54
The iron chelator deferasirox protects mice from mucormycosis through iron starvation. J Clin Invest (2007) 2.48
Mice with disseminated candidiasis die of progressive sepsis. J Infect Dis (2005) 2.42
ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells. EMBO Rep (2006) 2.26
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26
Current treatment strategies for disseminated candidiasis. Clin Infect Dis (2005) 2.25
Novel inhalational murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother (2004) 2.23
Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice. Hepatology (2014) 2.17
Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin-susceptible S. aureus infection: a prospective investigation. Clin Infect Dis (2007) 2.17
Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis. MBio (2012) 2.15
Pathogenesis of mucormycosis. Clin Infect Dis (2012) 2.14
Emerging role of epigenetics in the actions of alcohol. Alcohol Clin Exp Res (2008) 2.14
Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology (2012) 2.11
Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell (2009) 2.10
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest (2009) 2.06
Liposomal amphotericin B, and not amphotericin B deoxycholate, improves survival of diabetic mice infected with Rhizopus oryzae. Antimicrob Agents Chemother (2003) 2.01
Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage. Gastroenterology (2010) 2.00
Deferiprone iron chelation as a novel therapy for experimental mucormycosis. J Antimicrob Chemother (2006) 1.99
Candida albicans Hyr1p confers resistance to neutrophil killing and is a potential vaccine target. J Infect Dis (2010) 1.96
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
Combination therapy with amphotericin B lipid complex and caspofungin acetate of disseminated zygomycosis in diabetic ketoacidotic mice. Antimicrob Agents Chemother (2005) 1.90
Mutations in NR5A1 associated with ovarian insufficiency. N Engl J Med (2009) 1.88
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene. Oncogene (2004) 1.83
Regulation of murine cardiac 20S proteasomes: role of associating partners. Circ Res (2006) 1.81
Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun (2003) 1.78
The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus. Infect Immun (2008) 1.77
NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus, is safe and immunogenic in healthy adults. Vaccine (2012) 1.77
Steatohepatitis induced by intragastric overfeeding in mice. Hepatology (2005) 1.73
Draft genome of the kiwifruit Actinidia chinensis. Nat Commun (2013) 1.72
Progress toward a Staphylococcus aureus vaccine. Clin Infect Dis (2011) 1.72
Dr. William H. Stewart: mistaken or maligned? Clin Infect Dis (2008) 1.71
Oxidative stress and regulation of anti-oxidant enzymes in cytochrome P4502E1 transgenic mouse model of non-alcoholic fatty liver. J Gastroenterol Hepatol (2010) 1.68
Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency. J Clin Endocrinol Metab (2009) 1.68
Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis. J Infect Dis (2006) 1.64
Seven ways to preserve the miracle of antibiotics. Clin Infect Dis (2013) 1.63
Two small GTPases act in concert with the bactofilin cytoskeleton to regulate dynamic bacterial cell polarity. Dev Cell (2013) 1.63
Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia. Clin Cancer Res (2003) 1.62
Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro. Infect Immun (2004) 1.59
Crystal structure of quinone reductase 2 in complex with resveratrol. Biochemistry (2004) 1.59
The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice. Infect Immun (2005) 1.53
Mutations in the p53 tumor suppressor gene and early onset breast cancer. Cancer Biol Ther (2002) 1.52
Functional analysis of the Candida albicans ALS1 gene product. Yeast (2004) 1.50
Assessment of ischemia-modified albumin levels for emergency room diagnosis of acute coronary syndrome. Int J Cardiol (2010) 1.49
Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis. Mol Cell Biol (2006) 1.49
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. Exp Mol Pathol (2008) 1.48
Global cell surface conformational shift mediated by a Candida albicans adhesin. Infect Immun (2004) 1.46
Ultrastructural evidence of mitochondrial abnormalities in postresuscitation myocardial dysfunction. Resuscitation (2011) 1.46
Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. J Clin Invest (2012) 1.45