Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies.

PubWeight™: 1.49‹?› | Rank: Top 4%

🔗 View Article (PMC 2857348)

Published in Circulation on February 16, 2010

Authors

Jaime M Predmore1, Ping Wang, Frank Davis, Sarah Bartolone, Margaret V Westfall, David B Dyke, Francis Pagani, Saul R Powell, Sharlene M Day

Author Affiliations

1: 1150 W Medical Center Dr, 7301 MSRB III, Ann Arbor, MI 48109-0644, USA.

Articles citing this

Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins. Circulation (2013) 1.62

Thin filament mutations: developing an integrative approach to a complex disorder. Circ Res (2011) 1.55

Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice. J Clin Invest (2011) 1.48

Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy. Eur Heart J (2012) 1.44

Enhancement of proteasome function by PA28α overexpression protects against oxidative stress. FASEB J (2010) 1.40

Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy. Circ Res (2010) 1.34

Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice. Circ Res (2010) 1.24

Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in mice. Circ Res (2012) 1.15

Proteasomal and lysosomal protein degradation and heart disease. J Mol Cell Cardiol (2013) 1.12

Proteasome functional insufficiency in cardiac pathogenesis. Am J Physiol Heart Circ Physiol (2011) 1.11

Posttranslational modification and quality control. Circ Res (2013) 1.06

Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond. J Mol Cell Cardiol (2013) 1.03

Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways. J Am Heart Assoc (2013) 1.00

The ubiquitin proteasome system in human cardiomyopathies and heart failure. Am J Physiol Heart Circ Physiol (2013) 0.99

The role of the proteasome in heart disease. Biochim Biophys Acta (2010) 0.99

Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy. J Clin Invest (2014) 0.98

New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart. Oxid Med Cell Longev (2014) 0.98

Primary proteasome inhibition results in cardiac dysfunction. Eur J Heart Fail (2013) 0.96

The ubiquitin-proteasome system and cardiovascular disease. Prog Mol Biol Transl Sci (2012) 0.93

Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5. Circ Res (2012) 0.92

Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human. Mol Cell Proteomics (2013) 0.91

Sarcomere mutation-specific expression patterns in human hypertrophic cardiomyopathy. Circ Cardiovasc Genet (2014) 0.90

The ubiquitin proteasome system and myocardial ischemia. Am J Physiol Heart Circ Physiol (2012) 0.90

Protein quality control and metabolism: bidirectional control in the heart. Cell Metab (2015) 0.90

Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics. Am J Physiol Heart Circ Physiol (2012) 0.87

Research priorities in sarcomeric cardiomyopathies. Cardiovasc Res (2015) 0.86

New frontiers in heart hypertrophy during pregnancy. Am J Cardiovasc Dis (2012) 0.86

Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies. Antioxid Redox Signal (2014) 0.85

Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure. Am J Physiol Heart Circ Physiol (2013) 0.85

Pregnancy is associated with decreased cardiac proteasome activity and oxidative stress in mice. PLoS One (2012) 0.83

Impaired assembly and post-translational regulation of 26S proteasome in human end-stage heart failure. Circ Heart Fail (2013) 0.81

Cytokine-induced oxidative stress in cardiac inflammation and heart failure-how the ubiquitin proteasome system targets this vicious cycle. Front Physiol (2013) 0.81

The COP9 signalosome and cullin-RING ligases in the heart. Am J Cardiovasc Dis (2015) 0.81

A hypertrophic cardiomyopathy-associated MYBPC3 mutation common in populations of South Asian descent causes contractile dysfunction. J Biol Chem (2015) 0.80

Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci (2016) 0.79

Proteasome inhibition slightly improves cardiac function in mice with hypertrophic cardiomyopathy. Front Physiol (2014) 0.78

Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependent manner. J Mol Cell Cardiol (2014) 0.78

Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy. J Mol Cell Cardiol (2016) 0.78

Lysine ubiquitination and acetylation of human cardiac 20S proteasomes. Proteomics Clin Appl (2014) 0.78

Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support. Circ Heart Fail (2014) 0.78

Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy. Int J Mol Sci (2014) 0.77

A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci (2013) 0.76

Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy Phenotype. Front Physiol (2016) 0.76

Impact of leucine supplementation on exercise training induced anti-cardiac remodeling effect in heart failure mice. Nutrients (2015) 0.76

Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner. Circ Heart Fail (2016) 0.75

A comparative study of improvements Pre-filter methods bring on feature selection using microarray data. Health Inf Sci Syst (2014) 0.75

Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice. J Mol Cell Cardiol (2014) 0.75

Priming the proteasome by protein kinase G: a novel cardioprotective mechanism of sildenafil. Future Cardiol (2015) 0.75

Therapeutic landscape of carfilzomib and other modulators of the ubiquitin-proteasome pathway. J Clin Oncol (2015) 0.75

Ubiquitin and ubiquitin-like proteins in cardiac disease and protection. Curr Drug Targets (2015) 0.75

Quantitative evaluation of longitudinal strain in layer-specific myocardium during normal pregnancy in China. Cardiovasc Ultrasound (2016) 0.75

Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases. Exp Clin Cardiol (2012) 0.75

Mutations in proteasome-related genes are associated with thyroid hemiagenesis. Endocrine (2017) 0.75

Metabolic Origins of Heart Failure. JACC Basic Transl Sci (2017) 0.75

Proteostasis in cardiac health and disease. Nat Rev Cardiol (2017) 0.75

Articles cited by this

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev (2002) 16.10

Impairment of the ubiquitin-proteasome system by protein aggregation. Science (2001) 11.51

Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy. Circulation (2003) 5.85

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature (2007) 4.63

Myocytes die by multiple mechanisms in failing human hearts. Circ Res (2003) 3.61

Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation (2003) 3.55

Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation (1998) 3.41

The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res (2004) 3.37

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation. Mol Cell (2005) 3.28

Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation (2006) 2.50

Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake. Circ Res (2005) 2.49

Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. Proc Natl Acad Sci U S A (2004) 2.32

Mapping the murine cardiac 26S proteasome complexes. Circ Res (2006) 2.17

Heart failure and protein quality control. Circ Res (2006) 2.15

Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants. Cardiovasc Res (2005) 2.08

Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J Biol Chem (2001) 1.97

Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation (2008) 1.95

Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasome. J Biol Chem (2008) 1.93

Regulation of murine cardiac 20S proteasomes: role of associating partners. Circ Res (2006) 1.81

Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies. J Neurosci (2008) 1.79

Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy. Eur Heart J (2006) 1.78

Morning blood pressure surge as a destabilizing factor of atherosclerotic plaque: role of ubiquitin-proteasome activity. Hypertension (2007) 1.77

Hyperubiquitination of proteins in dilated cardiomyopathy. Proteomics (2003) 1.70

Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6. J Biol Chem (2007) 1.66

Sarcomeric genotyping in hypertrophic cardiomyopathy. Mayo Clin Proc (2005) 1.65

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol (2006) 1.54

The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases. Cell Mol Immunol (2006) 1.54

Proteasome inhibition promotes regression of left ventricular hypertrophy. Am J Physiol Heart Circ Physiol (2007) 1.50

The ubiquitin-proteasome system and skeletal muscle wasting. Essays Biochem (2005) 1.49

Markers of autophagy are downregulated in failing human heart after mechanical unloading. Circulation (2009) 1.48

Oxidized and ubiquitinated proteins may predict recovery of postischemic cardiac function: essential role of the proteasome. Antioxid Redox Signal (2005) 1.40

Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice. Biochem Biophys Res Commun (2005) 1.33

Assembly of the 26S proteasome is regulated by phosphorylation of the p45/Rpt6 ATPase subunit. Biochemistry (2001) 1.32

Optimal determination of heart tissue 26S-proteasome activity requires maximal stimulating ATP concentrations. J Mol Cell Cardiol (2006) 1.28

Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy. Cardiovasc Res (2008) 1.28

Suppression of cardiomyocyte hypertrophy by inhibition of the ubiquitin-proteasome system. Hypertension (2007) 1.26

Resistance exercise, muscle loading/unloading and the control of muscle mass. Essays Biochem (2006) 1.25

Proteasome plasticity. FEBS Lett (2005) 1.23

Requirement of dendritic Akt degradation by the ubiquitin-proteasome system for neuronal polarity. J Cell Biol (2006) 1.20

Aggregates of oxidized proteins (lipofuscin) induce apoptosis through proteasome inhibition and dysregulation of proapoptotic proteins. Free Radic Biol Med (2005) 1.11

Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart. J Am Coll Cardiol (2004) 1.07

Phosphorylation of proteasomes in mammalian cells. Identification of two phosphorylated subunits and the effect of phosphorylation on activity. Eur J Biochem (1996) 1.04

Exploring proteasome complexes by proteomic approaches. Proteomics (2007) 0.98

Upregulation of myocardial 11S-activated proteasome in experimental hyperglycemia. J Mol Cell Cardiol (2008) 0.96

Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes. Bioorg Med Chem Lett (2007) 0.94

Control of ubiquitination in skeletal muscle wasting. Int J Biochem Cell Biol (2004) 0.84

Articles by these authors

(truncated to the top 100)

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature (2002) 10.96

Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell (2012) 8.41

PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med (2004) 4.50

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. Genome Res (2008) 4.33

Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. Infect Immun (2003) 3.61

A PCR-based strategy to generate integrative targeting alleles with large regions of homology. Microbiology (2002) 3.58

Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later. J Pediatr (2007) 3.45

Dystrophic heart failure blocked by membrane sealant poloxamer. Nature (2005) 3.16

Poly[bis[aquaneodymium(III)]-mu2-oxalato-di-mu4-succinato]. Acta Crystallogr C (2007) 2.84

The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant (2013) 2.71

NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat Neurosci (2003) 2.70

Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet (2008) 2.63

RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. J Insect Physiol (2010) 2.47

A phase diagram for jammed matter. Nature (2008) 2.45

The effect of intraoperative rectal washout on local recurrence after rectal cancer surgery: a meta-analysis. Ann Surg Oncol (2012) 2.38

Relationship between neural, vascular, and BOLD signals in isoflurane-anesthetized rat somatosensory cortex. Cereb Cortex (2006) 2.28

Adenosine A2A receptor activation: another potential therapy for trauma and hemorrhagic shock. Crit Care Med (2006) 2.18

A heterozygous moth genome provides insights into herbivory and detoxification. Nat Genet (2013) 2.13

Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis. Circ Res (2006) 2.12

Endoscopic submucosal dissection for treatment of esophageal submucosal tumors originating from the muscularis propria layer. Gastrointest Endosc (2011) 2.08

A 70-year-old man with blue skin. Clin Chem (2014) 2.03

Structural insights into the YAP and TEAD complex. Genes Dev (2010) 2.00

Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology (2008) 1.97

Immune evasion versus recovery after acute hepatitis C virus infection from a shared source. J Exp Med (2005) 1.93

The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma. Crit Care Med (2006) 1.92

Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev (2013) 1.91

Cortical layer-dependent BOLD and CBV responses measured by spin-echo and gradient-echo fMRI: insights into hemodynamic regulation. Neuroimage (2006) 1.90

Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis. Proc Natl Acad Sci U S A (2005) 1.88

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice. Mamm Genome (2009) 1.87

Left ventricular assist device therapy improves utilization of donor hearts. J Am Coll Cardiol (2002) 1.85

Relationship between obesity and diabetes in a US adult population: findings from the National Health and Nutrition Examination Survey, 1999-2006. Obes Surg (2011) 1.85

Renal and hepatic function improve in advanced heart failure patients during continuous-flow support with the HeartMate II left ventricular assist device. Circulation (2009) 1.84

Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration. J Biol Chem (2003) 1.82

Covalent and noncovalent modification of thin filament action: the essential role of troponin in cardiac muscle regulation. Circ Res (2004) 1.80

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs. Nature (2008) 1.79

Antiangiogenic properties of gold nanoparticles. Clin Cancer Res (2005) 1.78

A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester. J Immunol Methods (2009) 1.78

Vitamin D deficiency, myositis-myalgia, and reversible statin intolerance. Curr Med Res Opin (2011) 1.77

Improved spatial localization of post-stimulus BOLD undershoot relative to positive BOLD. Neuroimage (2006) 1.76

PML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia. Cancer Cell (2010) 1.75

The immune protein CD3zeta is required for normal development of neural circuits in the retina. Neuron (2010) 1.74

Emergence of a new multidrug-resistant serotype X variant in an epidemic clone of Shigella flexneri. J Clin Microbiol (2009) 1.71

Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One (2010) 1.70

MR imaging of the amide-proton transfer effect and the pH-insensitive nuclear overhauser effect at 9.4 T. Magn Reson Med (2012) 1.67

Orexigenic hormone ghrelin ameliorates gut barrier dysfunction in sepsis in rats. Crit Care Med (2009) 1.67

Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway. Crit Care Med (2005) 1.66

Proinflammatory functions of vascular endothelial growth factor in alloimmunity. J Clin Invest (2003) 1.66

Prevention of sudden cardiac death with implantable cardioverter-defibrillators in children and adolescents with hypertrophic cardiomyopathy. J Am Coll Cardiol (2013) 1.65

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. Nucleic Acids Res (2013) 1.61

A review of statistical methods for expression quantitative trait loci mapping. Mamm Genome (2006) 1.60

A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol (2007) 1.60

Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera. Genetics (2011) 1.60

Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis. Crit Care Med (2002) 1.60

Decreased serum free testosterone in workers exposed to high levels of di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP): a cross-sectional study in China. Environ Health Perspect (2006) 1.60

Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities. Protein Sci (2008) 1.60

Evaluation of the human transmission risk of an atypical bovine spongiform encephalopathy prion strain. J Virol (2008) 1.59

Protective effect of milk fat globule-epidermal growth factor-factor VIII after renal ischemia-reperfusion injury in mice. Crit Care Med (2011) 1.58

Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa. Biochem J (2011) 1.57

Nonarteritic anterior ischemic optic neuropathy: associations with homozygosity for the C677T methylenetetrahydrofolate reductase mutation. J Lab Clin Med (2004) 1.57

C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I. Proc Natl Acad Sci U S A (2002) 1.56

Adipocyte extracellular matrix composition, dynamics and role in obesity. Cell Mol Life Sci (2010) 1.56

Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas. Histopathology (2011) 1.55

The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum Brain Mapp (2009) 1.55

Magnetic resonance imaging of the Amine-Proton EXchange (APEX) dependent contrast. Neuroimage (2011) 1.54

Procoagulants and osteonecrosis. J Rheumatol (2003) 1.54

Histidine button engineered into cardiac troponin I protects the ischemic and failing heart. Nat Med (2006) 1.53

Current trends in inflammatory and immunomodulatory mediators in sepsis. J Leukoc Biol (2012) 1.52

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity. J Clin Invest (2015) 1.52

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature (2016) 1.52

Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers. Mol Med (2009) 1.52

Specific role of tight junction proteins claudin-5, occludin, and ZO-1 of the blood-brain barrier in a focal cerebral ischemic insult. J Mol Neurosci (2011) 1.52

Modern analytical techniques in metabolomics analysis. Analyst (2011) 1.52

Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J Biol Chem (2007) 1.52

The physiologic effects of caloric restriction are reflected in the in vivo adipocyte-enriched proteome of overweight/obese subjects. J Proteome Res (2009) 1.51

Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks. PLoS One (2010) 1.51

Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equations. Pharmacogenomics (2008) 1.50

Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis. Shock (2006) 1.50

Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4. EMBO J (2008) 1.50

Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms. J Leukoc Biol (2004) 1.49

The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. J Biol Chem (2010) 1.48

Ghrelin down-regulates proinflammatory cytokines in sepsis through activation of the vagus nerve. Ann Surg (2007) 1.48

Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome. Metabolism (2003) 1.47

Quantitative vibrational imaging by hyperspectral stimulated Raman scattering microscopy and multivariate curve resolution analysis. Anal Chem (2012) 1.46

Retracted Triple reassortant swine influenza A (H3N2) virus in waterfowl. Emerg Infect Dis (2010) 1.46

The feasibility of using high resolution genome sequencing of influenza A viruses to detect mixed infections and quasispecies. PLoS One (2009) 1.46

Milk fat globule epidermal growth factor 8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion. Am J Respir Crit Care Med (2009) 1.45

Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95. J Mol Biol (2003) 1.45

Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis. J Lipid Res (2005) 1.43

Growth, motor, and social development in breast- and formula-fed infants of metformin-treated women with polycystic ovary syndrome. J Pediatr (2006) 1.43

Down-regulation of hepatic CYP1A2 plays an important role in inflammatory responses in sepsis. Crit Care Med (2004) 1.43

Differential alteration of two aminopeptidases N associated with resistance to Bacillus thuringiensis toxin Cry1Ac in cabbage looper. Proc Natl Acad Sci U S A (2011) 1.42

Correction of clinical manifestations of canine mucopolysaccharidosis I with neonatal retroviral vector gene therapy. Mol Ther (2007) 1.42

The child as proband for future parental cardiometabolic disease: the 26-year prospective Princeton Lipid Research Clinics Follow-up Study. J Pediatr (2012) 1.41

Oxidized and ubiquitinated proteins may predict recovery of postischemic cardiac function: essential role of the proteasome. Antioxid Redox Signal (2005) 1.40

Enhancement of proteasome function by PA28α overexpression protects against oxidative stress. FASEB J (2010) 1.40

Spatial specificity of cerebral blood volume-weighted fMRI responses at columnar resolution. Neuroimage (2005) 1.40

Function of small hydrophobic proteins of paramyxovirus. J Virol (2006) 1.39

Delayed electrocardiographic changes after percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy. J Electrocardiol (2007) 1.39

Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin. Hum Reprod (2002) 1.39