PubRank

Pierre Lebon

Author PubWeight™ 118.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus. Nat Genet 2006 6.15
2 TLR3 deficiency in patients with herpes simplex encephalitis. Science 2007 5.86
3 Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response. Nat Genet 2009 5.84
4 Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection. Nat Genet 2006 5.26
5 Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 2006 4.26
6 Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J Clin Invest 2009 3.89
7 Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages. J Clin Invest 2010 2.92
8 Clinical and molecular phenotype of Aicardi-Goutieres syndrome. Am J Hum Genet 2007 2.81
9 Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis 2002 2.71
10 Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature. Nat Genet 2012 2.63
11 Protein kinase cδ deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation. Arthritis Rheum 2013 2.60
12 Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome. Arthritis Rheum 2010 2.50
13 Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity 2010 2.47
14 Antigen crosspresentation by human plasmacytoid dendritic cells. Immunity 2007 2.42
15 Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study. Lancet Neurol 2013 2.36
16 Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Immunity 2005 2.16
17 Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression. Blood 2008 1.99
18 Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J Clin Invest 2011 1.88
19 Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature. Nat Genet 2011 1.84
20 Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity. J Exp Med 2011 1.71
21 Plasmacytoid dendritic cell dynamics and alpha interferon production during Simian immunodeficiency virus infection with a nonpathogenic outcome. J Virol 2008 1.62
22 Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease. Arthritis Rheum 2011 1.59
23 Coronavirus 229E-related pneumonia in immunocompromised patients. Clin Infect Dis 2003 1.58
24 Type I interferon production is profoundly and transiently impaired in primary HIV-1 infection. J Infect Dis 2005 1.54
25 Limits of early diagnosis of herpes simplex encephalitis in children: a retrospective study of 38 cases. Clin Infect Dis 2003 1.44
26 Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection. PLoS One 2012 1.39
27 Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood. J Exp Med 2012 1.35
28 HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes. AIDS Res Hum Retroviruses 2004 1.31
29 Type I interferon production in HIV-infected patients. J Leukoc Biol 2006 1.29
30 Evaluation of the one-step multiplex real-time reverse transcription-PCR ProFlu-1 assay for detection of influenza A and influenza B viruses and respiratory syncytial viruses in children. J Clin Microbiol 2007 1.28
31 Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways. Eur J Immunol 2008 1.27
32 Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood. J Pediatr 2010 1.21
33 The expanding spectrum of renal diseases associated with antiphospholipid syndrome. Am J Kidney Dis 2003 1.21
34 Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome. Glia 2008 1.18
35 Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1. Am J Med Genet A 2015 1.17
36 Type I interferon production by plasmacytoid dendritic cells and monocytes is triggered by viruses, but the level of production is controlled by distinct cytokines. J Interferon Cytokine Res 2002 1.09
37 The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome. Arthritis Rheum 2009 1.05
38 Guillain-Barré syndrome and influenza virus infection. Clin Infect Dis 2009 1.05
39 Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. N Engl J Med 2015 1.02
40 Incorporation of green fluorescent protein into the essential envelope glycoprotein B of herpes simplex virus type 1. J Virol Methods 2002 1.00
41 Hepatitis delta virus proteins repress hepatitis B virus enhancers and activate the alpha/beta interferon-inducible MxA gene. J Gen Virol 2009 0.98
42 Replication of respiratory viruses, particularly influenza virus, rhinovirus, and coronavirus in HuH7 hepatocarcinoma cell line. J Med Virol 2005 0.97
43 Reporter gene assay for the quantification of the activity and neutralizing antibody response to TNFα antagonists. J Immunol Methods 2011 0.96
44 Stimulation of the primary anti-HIV antibody response by IFN-alpha in patients with acute HIV-1 infection. J Leukoc Biol 2008 0.95
45 Serum procalcitonin and other biologic markers to distinguish between bacterial and aseptic meningitis. J Pediatr 2006 0.95
46 Type I interferon subtypes produced by human peripheral mononuclear cells from one normal donor stimulated by viral and non-viral inducing factors. Eur Cytokine Netw 2007 0.94
47 Active immunisation of human interferon α transgenic mice with a human interferon α Kinoid induces antibodies that neutralise interferon α in sera from patients with systemic lupus erythematosus. Ann Rheum Dis 2011 0.93
48 Pertussis and respiratory syncytial virus infections. Eur J Pediatr 2007 0.93
49 Severe herpes virus (HSV-2) infection in two patients with myelodysplasia and undetectable NK cells and plasmacytoid dendritic cells in the blood. J Clin Virol 2004 0.92
50 Procalcitonin is useful in identifying bacteraemia among children with pneumonia. Scand J Infect Dis 2010 0.89
51 Aicardi-Goutières syndrome: description of a late onset case. Dev Med Child Neurol 2008 0.87
52 IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells. Proc Natl Acad Sci U S A 2011 0.87
53 Elevated interferon-alpha in fetal blood in the prenatal diagnosis of Aicardi-Goutières syndrome. Fetal Diagn Ther 2006 0.86
54 Human bocavirus in children with acute asthma. Clin Infect Dis 2007 0.86
55 Human bocavirus infection in hospitalized children during winter. Pediatr Infect Dis J 2007 0.85
56 Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses. PLoS One 2013 0.85
57 Human bocavirus: a cause of severe asthma exacerbation in children. J Pediatr 2009 0.84
58 [Respiratory syncytial virus in hospitalized children. A 3-year study]. Presse Med 2007 0.83
59 Plasmacytoid dendritic cell reconstitution following bone marrow transplantation: subnormal recovery and functional deficit of IFN-alpha/beta production in response to herpes simplex virus. J Interferon Cytokine Res 2005 0.82
60 A cohort study of enfuvirtide immunological and virological efficacy in clinical practice. J Med Virol 2006 0.82
61 Synthetic scrapie infectivity: interaction between recombinant PrP and scrapie brain-derived RNA. Virulence 2015 0.81
62 Induction of B cell-activating factor by viral infection is a general phenomenon, but the types of viruses and mechanisms depend on cell type. J Innate Immun 2010 0.81
63 Risks versus benefits of NSAIDs including aspirin in myocarditis: a review of the evidence from animal studies. Drug Saf 2003 0.80
64 Guillain-Barré syndrome, greater Paris area. Emerg Infect Dis 2006 0.80
65 Effect of sublingual administration of interferon-alpha on the immune response to influenza vaccination in institutionalized elderly individuals. Vaccine 2008 0.80
66 One-step assay for quantification of neutralizing antibodies to biopharmaceuticals. J Immunol Methods 2010 0.80
67 Underestimation of influenza viral infection in childhood asthma exacerbations. J Pediatr 2010 0.80
68 Alpha-interferon secreting blastic plasmacytoid dendritic cells neoplasm: a case report with histological, molecular genetics and long-term tumor cells culture studies. Am J Dermatopathol 2012 0.79
69 Interferon-related transcriptome alterations in the cerebrospinal fluid cells of Aicardi-Goutières patients. Brain Pathol 2008 0.79
70 Prevalence of viral infection markers by polymerase chain reaction amplification and interferon-alpha measurements among patients undergoing lumbar puncture in an emergency department. J Med Virol 2004 0.78
71 Humoral immunity of dTap-IPV vaccine (REPEVAX®) administered one month after dT-IPV vaccine (REVAXIS®) in adults with unknown vaccination history. Hum Vaccin 2010 0.78
72 Elevation of proinflammatory cytokines in patients with Aicardi-Goutières syndrome. Neurology 2013 0.78
73 Acute myocarditis due to Chikungunya virus assessed by contrast-enhanced MRI. Int J Cardiol 2007 0.78
74 The burden of respiratory viral disease in hospitalized children in Paris. Eur J Pediatr 2007 0.77
75 Control of humoral immunity and auto-immunity by the CXCR4/CXCL12 axis in lupus patients following influenza vaccine. Vaccine 2013 0.77
76 Etiology and outcome of fetal echogenic bowel. Ten years of experience. Fetal Diagn Ther 2003 0.76
77 Late-onset neonatal infections caused by group B Streptococcus associated with viral infection. Pediatr Infect Dis J 2007 0.76
78 Delay in diagnosis of influenza virus in an elderly hospitalized patient: a fatal outcome. Clin Med Insights Case Rep 2012 0.75
79 Patients with systemic inflammatory and autoimmune diseases are at risk of vaccine-preventable illnesses. Rheumatology (Oxford) 2011 0.75
80 Atypical case of Aicardi-Goutières syndrome with late-onset myoclonic status. Epileptic Disord 2007 0.75
81 [Lower respiratory tract infections with influenza and respiratory syncytial viruses in hospitalized elderly patients during the 2005-2006 winter season]. Presse Med 2008 0.75