Published in Biochemistry on August 01, 2006
Porphyrins affect the self-assembly of tubulin in solution. Biophys Chem (2009) 0.75
Quantitative analysis of tau-microtubule interaction using FRET. Int J Mol Sci (2014) 0.75
Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment. Oncotarget (2011) 1.54
Apo-Hsp90 coexists in two open conformational states in solution. Biol Cell (2008) 1.39
Thermodynamics of heme binding to the HasA(SM) hemophore: effect of mutations at three key residues for heme uptake. Biochemistry (2003) 1.30
The heme transfer from the soluble HasA hemophore to its membrane-bound receptor HasR is driven by protein-protein interaction from a high to a lower affinity binding site. J Biol Chem (2006) 1.26
Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells. Cancer Res (2006) 1.24
DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose. Biochemistry (2002) 1.20
Binding of ATP to heat shock protein 90: evidence for an ATP-binding site in the C-terminal domain. J Biol Chem (2002) 1.17
Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J Biol Chem (2010) 1.15
The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis. J Biol Chem (2004) 1.13
Nox1-dependent superoxide production controls colon adenocarcinoma cell migration. Biochim Biophys Acta (2007) 1.10
HIV-1 Tat protein enhances microtubule polymerization. Retrovirology (2005) 1.06
Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. J Med Chem (2003) 1.04
Mito-DEPMPO synthesized from a novel NH2-reactive DEPMPO spin trap: a new and improved trap for the detection of superoxide. Chem Commun (Camb) (2007) 1.03
Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules. FASEB J (2008) 1.02
Tat HIV-1 primary and tertiary structures critical to immune response against non-homologous variants. J Biol Chem (2002) 1.00
Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection. Pharmacol Biochem Behav (2006) 0.98
Minimal effect of MDR1 and CYP3A5 genetic polymorphisms on the pharmacokinetics of indinavir in HIV-infected patients. Br J Clin Pharmacol (2007) 0.98
Tau induces ring and microtubule formation from alphabeta-tubulin dimers under nonassembly conditions. Biochemistry (2004) 0.98
NMR investigation of the interaction between the neuronal protein tau and the microtubules. Biochemistry (2007) 0.96
A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivo glioblastoma models. BMC Cancer (2009) 0.92
Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells. Int J Cancer (2008) 0.92
Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease. J Biol Chem (2003) 0.91
Low concentrations of vinflunine induce apoptosis in human SK-N-SH neuroblastoma cells through a postmitotic G1 arrest and a mitochondrial pathway. Mol Pharmacol (2004) 0.91
Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat. Retrovirology (2008) 0.90
Oligomeric-induced activity by thienyl pyrimidine compounds traps prion infectivity. J Neurosci (2011) 0.88
Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites. Mol Cancer Ther (2008) 0.88
Bcl-2-enhanced efficacy of microtubule-targeting chemotherapy through Bim overexpression: implications for cancer treatment. Neoplasia (2013) 0.88
Synthesis and antiprotozoal activity of 4-arylcoumarins. Eur J Med Chem (2009) 0.87
Molecular mechanisms of Tau binding to microtubules and its role in microtubule dynamics in live cells. J Cell Sci (2013) 0.87
Specific binding of dehydroepiandrosterone to the N terminus of the microtubule-associated protein MAP2. J Biol Chem (2003) 0.86
New insights into the antibacterial mechanism of action of squalamine. J Antimicrob Chemother (2010) 0.86
Vinflunine, a novel microtubule inhibitor, suppresses calmodulin interaction with the microtubule-associated protein STOP. Biochemistry (2007) 0.84
ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents. Oncotarget (2014) 0.84
Alpha-phenyl-N-tert-butylnitrone-type derivatives bound to beta-cyclodextrins: syntheses, thermokinetics of self-inclusion and application to superoxide spin-trapping. Chemistry (2007) 0.84
Calorimetry and mass spectrometry study of oxidized calmodulin interaction with target and differential repair by methionine sulfoxide reductases. Biochimie (2005) 0.83
Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine. Mol Cancer Ther (2006) 0.83
First tau repeat domain binding to growing and taxol-stabilized microtubules, and serine 262 residue phosphorylation. FEBS Lett (2002) 0.83
The type I/type II cytochrome c3 complex: an electron transfer link in the hydrogen-sulfate reduction pathway. J Mol Biol (2005) 0.82
Diastereoselective synthesis and ESR study of 4-phenylDEPMPO spin traps. J Org Chem (2005) 0.82
Stathmin/Op18 is a novel mediator of vinblastine activity. FEBS Lett (2008) 0.82
Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: synthesis, structure-activity relationship, and action mechanism studies. Eur J Med Chem (2008) 0.81
Tau aggregation in Alzheimer's disease: what role for phosphorylation? Prion (2007) 0.81
Mechanism of Tau-promoted microtubule assembly as probed by NMR spectroscopy. J Am Chem Soc (2014) 0.81
New Ianthelliformisamine derivatives as antibiotic enhancers against resistant Gram-negative bacteria. J Med Chem (2014) 0.80
Persilylated phosphoranyl radicals: the first persistent noncyclic phosphoranyl radicals. Chemistry (2006) 0.80
Inclusion complexes of EMPO derivatives with 2,6-di-O-methyl-beta-cyclodextrin: synthesis, NMR and EPR investigations for enhanced superoxide detection. Org Biomol Chem (2006) 0.80
Improving the trapping of superoxide radical with a beta-cyclodextrin- 5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide (DEPMPO) conjugate. Chemistry (2009) 0.80
New insights into tau-microtubules interaction revealed by isothermal titration calorimetry. Biochimie (2011) 0.79
Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2. J Med Chem (2011) 0.79
Biochemical and biophysical characterization of the Mg2+-induced 90-kDa heat shock protein oligomers. J Biol Chem (2010) 0.79
Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine. Anticancer Drugs (2006) 0.79
Synthesis and spin-trapping behavior of 5-ChEPMPO, a cholesteryl ester analogue of the spin trap DEPMPO. J Org Chem (2005) 0.79
Inclusion complexes of PBN-type nitrone spin traps and their superoxide spin adducts with cyclodextrin derivatives: parallel determination of the association constants by NMR titrations and 2D-EPR simulations. J Phys Chem B (2005) 0.79
FRET and FRAP imaging: approaches to characterise tau and stathmin interactions with microtubules in cells. Biol Cell (2013) 0.78
Photo-inducible cytotoxic and clastogenic activities of 3,6-di-substituted acridines obtained by acylation of proflavine. Eur J Med Chem (2009) 0.78
Retinoids repress Ah receptor CYP1A1 induction pathway through the SMRT corepressor. Biochem Biophys Res Commun (2004) 0.78
Hydrodynamic properties and quaternary structure of the 90 kDa heat-shock protein: effects of divalent cations. Biochemistry (2002) 0.78
Nitroxide bound beta-cyclodextrin: is there an inclusion complex? J Org Chem (2006) 0.77
Biochemical and structural studies of the oligomerization domain of the Nipah virus phosphoprotein: evidence for an elongated coiled-coil homotrimer. Virology (2013) 0.77
Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor. Bioorg Med Chem (2008) 0.77
Identification by single-strand conformational polymorphism analysis of known and new mutations of the CYP3A5 gene in a French population. Toxicol Lett (2006) 0.77
4-arylcoumarin analogues of combretastatins stimulate apoptosis of leukemic cells from chronic lymphocytic leukemia patients. Exp Hematol (2008) 0.76
Sexual and relationship intimacy among women with provoked vestibulodynia and their partners: associations with sexual satisfaction, sexual function, and pain self-efficacy. J Sex Med (2013) 0.76
Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR. Methods Cell Biol (2010) 0.76
Tumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancer. PLoS One (2012) 0.75
Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent. Med Chem (2009) 0.75
The indolylcoumarin COUFIN exhibits potent activity against renal carcinoma cells without affecting hematopoietic system. Anticancer Agents Med Chem (2014) 0.75
Synthesis and biological activity of 8-azapurine and pyrazolo[4,3-d]pyrimidine analogues of myoseverin. Eur J Med Chem (2006) 0.75
Caulerpenyne-colchicine hybrid: synthesis and biological evaluation. Bioorg Med Chem (2006) 0.75
Synthesis and complete assignment of the 1H and 13C NMR signals of new acetamido and aminoflavonoid derivatives. Magn Reson Chem (2010) 0.75
A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor. Bioorg Med Chem Lett (2004) 0.75
Cascade synthesis of polyoxygenated 6H,11H-[2]benzopyrano-[4,3-c][1]benzopyran-11-ones. J Org Chem (2007) 0.75