Published in Physiology (Bethesda) on August 01, 2006
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell (2008) 6.16
Nox proteins in signal transduction. Free Radic Biol Med (2009) 3.47
Vascular actions of estrogens: functional implications. Pharmacol Rev (2008) 2.52
Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells. Free Radic Biol Med (2008) 2.35
Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int (2011) 2.15
Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J Biol Chem (2009) 2.08
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol (2009) 2.01
Arsenic and cardiovascular disease. Toxicol Sci (2008) 1.90
Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72
CaMKII in the cardiovascular system: sensing redox states. Physiol Rev (2011) 1.67
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The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells. Kidney Int (2012) 1.58
Aiding and abetting roles of NOX oxidases in cellular transformation. Nat Rev Cancer (2012) 1.57
Reactive oxygen species and the control of vascular function. Am J Physiol Heart Circ Physiol (2009) 1.50
The role of oxidative stress and NADPH oxidase in cerebrovascular disease. Trends Mol Med (2008) 1.46
Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. Mol Biol Cell (2007) 1.41
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. Nat Commun (2015) 1.37
Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase-generated superoxide. J Clin Invest (2008) 1.33
Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species. Mol Biol Cell (2010) 1.25
NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets. Am J Physiol Lung Cell Mol Physiol (2009) 1.20
Targeting NADPH oxidases in vascular pharmacology. Vascul Pharmacol (2012) 1.20
Oxidant and redox signaling in vascular oxygen sensing: implications for systemic and pulmonary hypertension. Antioxid Redox Signal (2008) 1.18
Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone. J Biol Chem (2011) 1.17
20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol (2008) 1.15
Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers. Mol Pharmacol (2008) 1.13
Sudden cardio arrest: oxidative stress irritates the heart. Nat Med (2010) 1.12
An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation. Arterioscler Thromb Vasc Biol (2010) 1.10
Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2008) 1.09
Regulation of NAD(P)H oxidases by AMPK in cardiovascular systems. Free Radic Biol Med (2012) 1.07
Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction. Am J Physiol Heart Circ Physiol (2009) 1.06
Differential regulation of EHD3 in human and mammalian heart failure. J Mol Cell Cardiol (2012) 1.02
Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration. J Pharmacol Exp Ther (2012) 0.99
Cyclosporine up-regulates Krüppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo. J Pharmacol Exp Ther (2010) 0.99
Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome. Am J Physiol Heart Circ Physiol (2009) 0.97
Age-related changes in redox signaling and VSMC function. Antioxid Redox Signal (2010) 0.97
Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration. Am J Physiol Heart Circ Physiol (2008) 0.97
Differential roles of NADPH oxidases in vascular physiology and pathophysiology. Front Biosci (Schol Ed) (2012) 0.95
NADPH oxidase expression and production of superoxide by human corneal stromal cells. Mol Vis (2009) 0.95
Sex differences in protection against angiotensin II-induced endothelial dysfunction by manganese superoxide dismutase in the cerebral circulation. Hypertension (2010) 0.93
Vascular smooth muscle modulates endothelial control of vasoreactivity via reactive oxygen species production through myoendothelial communications. PLoS One (2009) 0.91
Overexpression of catalase in myeloid cells causes impaired postischemic neovascularization. Arterioscler Thromb Vasc Biol (2011) 0.89
Activation-dependent stabilization of the human thromboxane receptor: role of reactive oxygen species. J Lipid Res (2009) 0.89
Dysfunction of endothelial and smooth muscle cells in small arteries of a mouse model of Marfan syndrome. Br J Pharmacol (2009) 0.88
Effects of N-acetylcysteine on nicotinamide dinucleotide phosphate oxidase activation and antioxidant status in heart, lung, liver and kidney in streptozotocin-induced diabetic rats. Yonsei Med J (2012) 0.88
Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension. Free Radic Biol Med (2015) 0.88
Functional pseudogenes inhibit the superoxide production. Precis Med (2015) 0.85
Estrogen receptor-α but not -β or GPER inhibits high glucose-induced human VSMC proliferation: potential role of ROS and ERK. J Clin Endocrinol Metab (2010) 0.84
The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure. J Cell Mol Med (2008) 0.83
Nitroglycerine-induced nitrate tolerance compromises propofol protection of the endothelial cells against TNF-α: the role of PKC-β2 and NADPH oxidase. Oxid Med Cell Longev (2013) 0.83
Cellular mechanisms underlying nitric oxide-induced vasodilation of descending vasa recta. Am J Physiol Renal Physiol (2010) 0.83
Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice. J Cell Mol Med (2011) 0.82
Hypertension and chronic ethanol consumption: What do we know after a century of study? World J Cardiol (2014) 0.82
Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells. Exp Mol Med (2009) 0.82
Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1. Cardiovasc Res (2010) 0.82
The small GTPase Rac1 is required for smooth muscle contraction. J Physiol (2013) 0.81
NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress. Antioxid Redox Signal (2014) 0.81
Small interfering peptide (siP) for in vivo examination of the developing lung interactonome. Dev Dyn (2009) 0.81
Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways. J Biol Chem (2013) 0.81
Artemisinin attenuates platelet-derived growth factor BB-induced migration of vascular smooth muscle cells. Nutr Res Pract (2014) 0.80
Pulmonary arterial responses to reactive oxygen species are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension. Pediatr Res (2011) 0.80
TRAIL promotes caspase-dependent pro-inflammatory responses via PKCδ activation by vascular smooth muscle cells. Cell Death Dis (2011) 0.80
Reactive oxygen species effect PASMCs apoptosis via regulation of dynamin-related protein 1 in hypoxic pulmonary hypertension. Histochem Cell Biol (2016) 0.79
Mechanical stretch-induced vascular hypertrophy occurs through modulation of leptin synthesis-mediated ROS formation and GATA-4 nuclear translocation. Front Pharmacol (2015) 0.79
Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis. Atherosclerosis (2014) 0.79
NADPH oxidase: recent evidence for its role in erectile dysfunction. Asian J Androl (2008) 0.78
Expression of NADPH oxidase (NOX) 5 in rabbit corneal stromal cells. PLoS One (2012) 0.78
Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury. Sci Rep (2016) 0.78
Function and design of the Nox1 system in vascular smooth muscle cells. BMC Syst Biol (2013) 0.78
The role of Nox-mediated oxidation in the regulation of cytoskeletal dynamics. Curr Pharm Des (2015) 0.77
Nox4-dependent activation of cofilin mediates VSMC reorientation in response to cyclic stretching. Free Radic Biol Med (2015) 0.77
Smooth muscle specific overexpression of p22phox potentiates carotid artery wall thickening in response to injury. Oxid Med Cell Longev (2015) 0.77
Vasotrophic regulation of age-dependent hypoxic cerebrovascular remodeling. Curr Vasc Pharmacol (2013) 0.76
Upregulation of intermediate-conductance Ca2+-activated K+ channels (KCNN4) in porcine coronary smooth muscle requires NADPH oxidase 5 (NOX5). PLoS One (2014) 0.76
Coronary endothelial function and vascular smooth muscle proliferation are programmed by early-gestation dexamethasone exposure in sheep. Am J Physiol Regul Integr Comp Physiol (2010) 0.76
An updated concept for left ventricular hypertrophy risk in hypertension. Ochsner J (2009) 0.76
Protein Kinase C as Regulator of Vascular Smooth Muscle Function and Potential Target in Vascular Disorders. Adv Pharmacol (2016) 0.75
Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells. Sci Rep (2016) 0.75
Circadian influences on myocardial infarction. Front Physiol (2014) 0.75
Killing Me Unsoftly: Causes and Mechanisms of Arterial Stiffness. Arterioscler Thromb Vasc Biol (2017) 0.75
NOX1-induced accumulation of reactive oxygen species in abdominal fat-derived mesenchymal stromal cells impinges on long-term proliferation. Cell Death Dis (2015) 0.75
The orphan nuclear receptor Nur77 inhibits low shear stress-induced carotid artery remodeling in mice. Int J Mol Med (2015) 0.75
Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness. Hypertension (2016) 0.75
Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth. Open Cardiovasc Med J (2017) 0.75
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol (2006) 7.84
Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2003) 4.56
Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation (2002) 3.95
Role of oxidative stress in atherosclerosis. Am J Cardiol (2003) 3.66
Nox proteins in signal transduction. Free Radic Biol Med (2009) 3.47
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase. J Biol Chem (2004) 3.37
Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ Res (2002) 3.32
Measurement of reactive oxygen species in cardiovascular studies. Hypertension (2007) 3.17
Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension (2003) 3.15
Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2006) 3.13
The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci (2003) 3.13
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation (2005) 3.12
Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury. Arterioscler Thromb Vasc Biol (2002) 3.10
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov (2011) 3.08
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res (2012) 3.02
Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circ Res (2009) 2.83
NADPH oxidases: functions and pathologies in the vasculature. Arterioscler Thromb Vasc Biol (2009) 2.83
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. Free Radic Biol Med (2008) 2.68
NADPH oxidases and angiotensin II receptor signaling. Mol Cell Endocrinol (2008) 2.22
Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. Congest Heart Fail (2002) 2.18
Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. J Biol Chem (2003) 2.09
Oxidative stress and diabetic cardiovascular complications. Free Radic Biol Med (2005) 2.05
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol (2009) 2.01
Reactive oxygen species signaling in vascular smooth muscle cells. Cardiovasc Res (2006) 1.89
Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury. Trends Cardiovasc Med (2007) 1.81
Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease. J Renin Angiotensin Aldosterone Syst (2003) 1.73
NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling. Antioxid Redox Signal (2002) 1.64
Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. Am J Physiol Heart Circ Physiol (2007) 1.57
Peroxisome proliferator-activated receptor-gamma ligands regulate endothelial membrane superoxide production. Am J Physiol Cell Physiol (2004) 1.57
Reactive oxygen species in hypertension; An update. Am J Hypertens (2004) 1.56
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med (2011) 1.56
Redox signaling, vascular function, and hypertension. Antioxid Redox Signal (2008) 1.52
Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2. Hypertension (2005) 1.49
Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arterioscler Thromb Vasc Biol (2007) 1.47
NADPH oxidase inhibitors: new antihypertensive agents? J Cardiovasc Pharmacol (2007) 1.44
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression. J Biol Chem (2008) 1.43
RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response. Hypertension (2006) 1.41
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. Free Radic Biol Med (2005) 1.36
Functional association of nox1 with p22phox in vascular smooth muscle cells. Free Radic Biol Med (2004) 1.34
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. Am J Physiol Heart Circ Physiol (2010) 1.31
Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle. Am J Physiol Heart Circ Physiol (2004) 1.29
Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells. Free Radic Biol Med (2008) 1.27
Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice. Am J Physiol Heart Circ Physiol (2004) 1.26
Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. Antioxid Redox Signal (2013) 1.26
Career development of physician scientists: a survey of leaders in academic medicine. Am J Med (2011) 1.26
Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells. Am J Physiol Cell Physiol (2004) 1.26
Reactive oxygen species, NADPH oxidases, and hypertension. Hypertension (2010) 1.24
Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions. Mol Cell Biol (2003) 1.23
Mechanisms of reactive oxygen species-dependent downregulation of insulin receptor substrate-1 by angiotensin II. Arterioscler Thromb Vasc Biol (2005) 1.22
NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor. Free Radic Biol Med (2010) 1.18
Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells. Circ Res (2007) 1.17
C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils. Hypertension (2004) 1.12
Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. J Biol Chem (2003) 1.12
Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products. Free Radic Biol Med (2007) 1.10
Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species. J Biol Chem (2003) 1.08
Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol Pharmacol (2002) 1.07
Redox control of vascular smooth muscle migration. Antioxid Redox Signal (2010) 1.06
Mechanism of hydrogen peroxide-induced cell cycle arrest in vascular smooth muscle. Antioxid Redox Signal (2002) 1.06
Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: comparison of sensitivity and specificity. Methods Mol Med (2007) 1.03
NADPH oxidases: new regulators of old functions. Antioxid Redox Signal (2006) 1.01
Differential effects of AT1 receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species. Atherosclerosis (2007) 0.99
Oxidative stress and diabetic vascular complications. Curr Diab Rep (2004) 0.96
Differential roles of NADPH oxidases in vascular physiology and pathophysiology. Front Biosci (Schol Ed) (2012) 0.95
NADPH oxidases: molecular understanding finally reaching the clinical level? Antioxid Redox Signal (2009) 0.93
Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2. Mol Pharmacol (2005) 0.91
Functional evaluation of nonphagocytic NAD(P)H oxidases. Methods Enzymol (2002) 0.91
Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. J Biol Chem (2011) 0.88
The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease. Antioxid Redox Signal (2002) 0.88
Polymerase delta interacting protein 2 sustains vascular structure and function. Arterioscler Thromb Vasc Biol (2013) 0.87
Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2009) 0.87
Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9. J Vasc Res (2012) 0.87
Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. Mol Pharmacol (2003) 0.85
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. J Biol Chem (2003) 0.84
Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor. Exp Cell Res (2011) 0.83
Transforming growth factor β inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation. PLoS One (2013) 0.83
Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association. Circ Res (2016) 0.83
NADPH oxidases: progress and opportunities. Antioxid Redox Signal (2014) 0.81
Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK. Am J Physiol Cell Physiol (2011) 0.81
Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways. J Biol Chem (2013) 0.81
The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice. Am J Physiol Heart Circ Physiol (2013) 0.79
Nox is playing with a full deck in vascular smooth muscle, a commentary on "Noxa1 is a central component of the smooth muscle NADPH oxidase in mice". Free Radic Biol Med (2006) 0.79
The yin/yang of superoxide dismutase mimetics: potential cardiovascular therapies? Br J Pharmacol (2003) 0.77
Mycophenolic acid is a new Nox2 inhibitor. Hypertension (2006) 0.77
Out phoxing the endothelium: what's left without p47? Circ Res (2002) 0.77
Redox control of growth factor signaling in heart, lung, and circulation. Antioxid Redox Signal (2003) 0.76
Angiotensin II, from vasoconstrictor to growth factor: a paradigm shift. Circ Res (2014) 0.75
Notice of retraction. Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2001;21:489-95. Arterioscler Thromb Vasc Biol (2013) 0.75
Polymerase δ-interacting Protein 2: A Multifunctional Protein. J Cardiovasc Pharmacol (2017) 0.75
Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. Circ Res (2017) 0.75