Nox proteins in signal transduction.

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Published in Free Radic Biol Med on July 21, 2009

Authors

David I Brown1, Kathy K Griendling

Author Affiliations

1: Department of Medicine, Division of Cardiology, Emory University, 1639 Pierce Drive, 319 WMB Atlanta, GA 30322, USA.

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NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor. Free Radic Biol Med (2010) 1.18

Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells. Circ Res (2007) 1.17

C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils. Hypertension (2004) 1.12

Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. J Biol Chem (2003) 1.12

Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products. Free Radic Biol Med (2007) 1.10

Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species. J Biol Chem (2003) 1.08

Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol Pharmacol (2002) 1.07

Redox control of vascular smooth muscle migration. Antioxid Redox Signal (2010) 1.06

Mechanism of hydrogen peroxide-induced cell cycle arrest in vascular smooth muscle. Antioxid Redox Signal (2002) 1.06

Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: comparison of sensitivity and specificity. Methods Mol Med (2007) 1.03

NADPH oxidases: new regulators of old functions. Antioxid Redox Signal (2006) 1.01

Differential effects of AT1 receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species. Atherosclerosis (2007) 0.99

Oxidative stress and diabetic vascular complications. Curr Diab Rep (2004) 0.96

Differential roles of NADPH oxidases in vascular physiology and pathophysiology. Front Biosci (Schol Ed) (2012) 0.95

NADPH oxidases: molecular understanding finally reaching the clinical level? Antioxid Redox Signal (2009) 0.93

Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2. Mol Pharmacol (2005) 0.91

Functional evaluation of nonphagocytic NAD(P)H oxidases. Methods Enzymol (2002) 0.91

Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. J Biol Chem (2011) 0.88

The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease. Antioxid Redox Signal (2002) 0.88

Polymerase delta interacting protein 2 sustains vascular structure and function. Arterioscler Thromb Vasc Biol (2013) 0.87

Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2009) 0.87

Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9. J Vasc Res (2012) 0.87

Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. Mol Pharmacol (2003) 0.85

Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. J Biol Chem (2003) 0.84

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor. Exp Cell Res (2011) 0.83

Transforming growth factor β inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation. PLoS One (2013) 0.83

Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association. Circ Res (2016) 0.83

NADPH oxidases: progress and opportunities. Antioxid Redox Signal (2014) 0.81

Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK. Am J Physiol Cell Physiol (2011) 0.81

Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways. J Biol Chem (2013) 0.81

The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice. Am J Physiol Heart Circ Physiol (2013) 0.79

Nox is playing with a full deck in vascular smooth muscle, a commentary on "Noxa1 is a central component of the smooth muscle NADPH oxidase in mice". Free Radic Biol Med (2006) 0.79

The yin/yang of superoxide dismutase mimetics: potential cardiovascular therapies? Br J Pharmacol (2003) 0.77

Mycophenolic acid is a new Nox2 inhibitor. Hypertension (2006) 0.77

Out phoxing the endothelium: what's left without p47? Circ Res (2002) 0.77

Redox control of growth factor signaling in heart, lung, and circulation. Antioxid Redox Signal (2003) 0.76

Angiotensin II, from vasoconstrictor to growth factor: a paradigm shift. Circ Res (2014) 0.75

Notice of retraction. Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2001;21:489-95. Arterioscler Thromb Vasc Biol (2013) 0.75

Polymerase δ-interacting Protein 2: A Multifunctional Protein. J Cardiovasc Pharmacol (2017) 0.75

Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. Circ Res (2017) 0.75