Published in J Biol Chem on July 31, 2006
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The effects of the histone deacetylase inhibitor romidepsin (FK228) are enhanced by aspirin (ASA) in COX-1 positive ovarian cancer cells through augmentation of p21. Cancer Biol Ther (2010) 0.86
Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells. Am J Pathol (2008) 0.85
Aspirin-induced Bcl-2 translocation and its phosphorylation in the nucleus trigger apoptosis in breast cancer cells. Exp Mol Med (2013) 0.84
Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. Int J Colorectal Dis (2010) 0.82
Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition. Lab Invest (2015) 0.81
The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells. Oxid Med Cell Longev (2013) 0.80
Aspirin delimits platelet life span by proteasomal inhibition. PLoS One (2014) 0.78
Effects of 2-bromoethanamine on TonEBP expression and its possible role in induction of renal papillary necrosis in mice. Toxicol Sci (2010) 0.77
Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol (2016) 0.75
Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin. Breast Cancer Res Treat (2016) 0.75
Does aspirin-induced oxidative stress cause asthma exacerbation? Arch Med Sci (2015) 0.75
Aspirin induces cell death by directly modulating mitochondrial voltage-dependent anion channel (VDAC). Sci Rep (2017) 0.75
Mitochondrial Malfunctioning, Proteasome Arrest and Apoptosis in Cancer Cells by Focused Intracellular Generation of Oxygen Radicals. Int J Mol Sci (2015) 0.75
Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions. J Neurochem (2004) 1.98
Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes. J Biol Chem (2005) 1.88
Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein. Nat Biotechnol (2010) 1.38
Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J Biol Chem (2003) 1.26
Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism. Hum Mol Genet (2008) 1.14
Inhibition of Rho kinases enhances the degradation of mutant huntingtin. J Biol Chem (2009) 1.10
UBE3A/E6-AP regulates cell proliferation by promoting proteasomal degradation of p27. Neurobiol Dis (2009) 1.04
The ubiquitin ligase E6-AP promotes degradation of alpha-synuclein. J Neurochem (2009) 1.01
The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins. J Biol Chem (2009) 1.00
Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction. Biochem Biophys Res Commun (2006) 1.00
Large-angle strabismus and primary true muscle transplantation. J Pediatr Ophthalmol Strabismus (2005) 0.99
E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity. J Biol Chem (2008) 0.99
Co-chaperone CHIP stabilizes aggregate-prone malin, a ubiquitin ligase mutated in Lafora disease. J Biol Chem (2009) 0.99
Loss of dopaminergic neurons and resulting behavioural deficits in mouse model of Angelman syndrome. Neurobiol Dis (2010) 0.98
Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin. Hum Mol Genet (2010) 0.93
The co-chaperone CHIP is induced in various stresses and confers protection to cells. Biochem Biophys Res Commun (2007) 0.91
Curcumin induces stress response, neurite outgrowth and prevent NF-kappaB activation by inhibiting the proteasome function. Neurotox Res (2006) 0.91
Myopathy in Marinesco-Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology. Acta Neuropathol (2013) 0.89
Malin regulates Wnt signaling pathway through degradation of dishevelled2. J Biol Chem (2012) 0.89
Defective glucocorticoid hormone receptor signaling leads to increased stress and anxiety in a mouse model of Angelman syndrome. Hum Mol Genet (2012) 0.88
Non-technical skills assessment in surgery. Surg Oncol (2010) 0.88
Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction. Biochem Biophys Res Commun (2006) 0.87
Lafora disease ubiquitin ligase malin promotes proteasomal degradation of neuronatin and regulates glycogen synthesis. Neurobiol Dis (2011) 0.87
E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. Neurobiol Aging (2012) 0.86
PLGA nanoparticle formulations of risperidone: preparation and neuropharmacological evaluation. Nanomedicine (2009) 0.86
Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochondria in tumor drug resistance? Tumour Biol (2011) 0.85
Capsaicin induces apoptosis through ubiquitin-proteasome system dysfunction. J Cell Biochem (2010) 0.84
Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease. Hum Mol Genet (2013) 0.83
Bayesian estimates of the prevalence of β-thalassemia trait in voluntary blood donors of central India: a survey. Hemoglobin (2010) 0.83
Reversal of reduced parvalbumin neurons in hippocampus and amygdala of Angelman syndrome model mice by chronic treatment of fluoxetine. J Neurochem (2014) 0.82
Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction. J Neurochem (2009) 0.82
MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdh(Q111)/Hdh(Q111) cells. Biochem Biophys Res Commun (2013) 0.82
Dysfunction of the ubiquitin ligase Ube3a may be associated with synaptic pathophysiology in a mouse model of Huntington disease. J Biol Chem (2012) 0.82
Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease. J Biol Chem (2013) 0.81
Stimulus-responsive targeted nanomicelles for effective cancer therapy. Nanomedicine (Lond) (2009) 0.79
Misfolded proteins recognition strategies of E3 ubiquitin ligases and neurodegenerative diseases. Mol Neurobiol (2012) 0.79
Pharmacological profile of AW-814141, a novel, potent, selective and orally active inhibitor of p38 MAP kinase. Int Immunopharmacol (2010) 0.79
Functional screening of adrenergic receptors by measuring intracellular calcium using the FlexStation scanning fluorimeter. Biotechnol J (2009) 0.79
E3 ubiquitin ligases in protein quality control mechanism. Mol Neurobiol (2012) 0.78
A novel C-terminal region within the multicargo type III secretion chaperone CesT contributes to effector secretion. J Bacteriol (2012) 0.78
Radiologic bone remodeling pattern around DCPD-coated, metaphyseal-loading cementless short stems in elderly patients. Orthopedics (2014) 0.78
Ratiometric Ca+2 measurement in human recombinant muscarinic receptor subtypes using the Flexstation scanning fluorometer. J Recept Signal Transduct Res (2009) 0.78
Protein quality control system in neurodegeneration: a healing company hard to beat but failure is fatal. Mol Neurobiol (2013) 0.78
Delayed Cell Cycle Progression in STHdh(Q111)/Hdh(Q111) Cells, a Cell Model for Huntington's Disease Mediated by microRNA-19a, microRNA-146a and microRNA-432. Microrna (2015) 0.77
Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity. Sci Rep (2013) 0.77
Role of ubiquitin protein ligases in the pathogenesis of polyglutamine diseases. Neurochem Res (2007) 0.77
Expression of expanded polyglutamine proteins suppresses the activation of transcription factor NFkappaB. J Biol Chem (2006) 0.77
Autophagy coupling interplay: can improve cellular repair and aging? Mol Neurobiol (2014) 0.76
ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT. Mol Neurodegener (2012) 0.76
Optimization and validation of a reporter gene assay for screening of phosphodiesterase inhibitors in a high throughput system. Biotechnol J (2008) 0.75
Myricetin reduces toxic level of CAG repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs). ACS Chem Biol (2017) 0.75
Development of polymeric nanoparticles with highly entrapped herbal hydrophilic drug using nanoprecipitation technique: an approach of quality by design. Pharm Dev Technol (2014) 0.75
Measurement techniques and instruments for airborne nanoparticles. J Biomed Nanotechnol (2011) 0.75
Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease. Hum Mol Genet (2017) 0.75
An improved zinc cocktail-mediated fluorescence polarization-based kinase assay for high-throughput screening of kinase inhibitors. Anal Biochem (2008) 0.75
Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. Ther Deliv (2010) 0.75