Published in Mol Biosyst on May 17, 2006
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High-throughput sequencing of peptoids and peptide-peptoid hybrids by partial edman degradation and mass spectrometry. J Comb Chem (2009) 1.11
Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex. Mol Cell Biol (2012) 0.96
TAp63 regulates oncogenic miR-155 to mediate migration and tumour growth. Oncotarget (2013) 0.84
Hepatitis B virus X protein enhances Myc stability by inhibiting SCF(Skp2) ubiquitin E3 ligase-mediated Myc ubiquitination and contributes to oncogenesis. Oncogene (2015) 0.81
Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity. Int J Nanomedicine (2014) 0.77
Preliminary study of a novel transfection modality for in vivo siRNA delivery to vocal fold fibroblasts. Laryngoscope (2016) 0.75
A rotamer library to enable modeling and design of peptoid foldamers. J Am Chem Soc (2014) 0.75
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Unlocking the secrets of the genome. Nature (2009) 11.80
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature (2002) 10.96
A genome-wide map of conserved microRNA targets in C. elegans. Curr Biol (2006) 10.14
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
The SCF ubiquitin ligase: insights into a molecular machine. Nat Rev Mol Cell Biol (2004) 8.21
Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors. Clin Cancer Res (2006) 6.91
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer (2008) 6.10
S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science (2006) 5.94
A compendium of RNA-binding motifs for decoding gene regulation. Nature (2013) 4.91
Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev (2004) 4.68
The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell (2008) 4.04
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature (2004) 3.73
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase. J Biol Chem (2003) 3.68
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature (2005) 3.62
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Dev Cell (2003) 3.62
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science (2007) 3.59
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature (2003) 3.54
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev (2008) 3.49
Caenorhabditis phylogeny predicts convergence of hermaphroditism and extensive intron loss. Proc Natl Acad Sci U S A (2004) 3.47
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest (2002) 3.36
The landscape of C. elegans 3'UTRs. Science (2010) 3.32
Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature (2006) 3.31
Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer. J Clin Invest (2009) 3.14
The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science (2007) 3.05
American Idol and NIH Grant Review. Cell (2006) 3.01
SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol Cell (2006) 2.75
Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase. Mol Cell (2005) 2.75
In vitro self-assembly of tailorable nanotubes from a simple protein building block. Proc Natl Acad Sci U S A (2008) 2.71
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell (2011) 2.64
Mechanisms and function of substrate recruitment by F-box proteins. Nat Rev Mol Cell Biol (2013) 2.56
Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation. Cell (2003) 2.54
ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res (2012) 2.51
Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Curr Biol (2002) 2.47
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature (2008) 2.46
APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Mol Cell (2007) 2.35
Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc Natl Acad Sci U S A (2008) 2.35
Specific small molecule inhibitors of Skp2-mediated p27 degradation. Chem Biol (2012) 2.34
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol (2008) 2.32
Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin Cancer Biol (2003) 2.27
A protein domain-based interactome network for C. elegans early embryogenesis. Cell (2008) 2.23
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes. Nature (2007) 2.20
SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature (2010) 2.15
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation. Nat Struct Mol Biol (2004) 2.11
Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. J Cell Biol (2008) 2.08
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome. Proc Natl Acad Sci U S A (2004) 2.05
Comparative analysis of algorithms for signal quantitation from oligonucleotide microarrays. Bioinformatics (2004) 2.04
Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair. Cell (2012) 1.98
Dual mode of degradation of Cdc25 A phosphatase. EMBO J (2002) 1.95
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. Cell Cycle (2009) 1.94
USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110. Nature (2013) 1.94
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans. J Clin Invest (2010) 1.93
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state. Cell Cycle (2008) 1.90
SnapShot: F Box Proteins II. Cell (2009) 1.88
Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions. Mol Cell Biol (2003) 1.85
Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression. Nat Methods (2009) 1.82
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature (2012) 1.79
EGG-4 and EGG-5 Link Events of the Oocyte-to-Embryo Transition with Meiotic Progression in C. elegans. Curr Biol (2009) 1.79
mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR. Mol Cell (2011) 1.78
Stimulation of prostate cancer cellular proliferation and invasion by the androgen receptor co-activator ARA70. Am J Pathol (2007) 1.77
betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. Mol Cell (2009) 1.77
RNAiDB and PhenoBlast: web tools for genome-wide phenotypic mapping projects. Nucleic Acids Res (2004) 1.74
Gold nanoparticle self-similar chain structure organized by DNA origami. J Am Chem Soc (2010) 1.67
Viral nanoparticles donning a paramagnetic coat: conjugation of MRI contrast agents to the MS2 capsid. Nano Lett (2006) 1.67
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase. Chem Biol (2010) 1.60
Sequence characteristics of functional siRNAs. RNA (2005) 1.59
Toward automatic phenotyping of developing embryos from videos. IEEE Trans Image Process (2005) 1.58
Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling. Nat Chem Biol (2013) 1.57
Control of cell growth by the SCF and APC/C ubiquitin ligases. Curr Opin Cell Biol (2009) 1.55
An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant. Mol Cell (2004) 1.55
Oncogenic aberrations of cullin-dependent ubiquitin ligases. Oncogene (2004) 1.51
Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates. J Am Chem Soc (2006) 1.50
Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nat Cell Biol (2012) 1.47
MEL-28 is downstream of the Ran cycle and is required for nuclear-envelope function and chromatin maintenance. Curr Biol (2006) 1.46
Stabilizers and destabilizers controlling cell cycle oscillators. Mol Cell (2006) 1.42
SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature (2013) 1.41
Structural and spectroscopic studies of peptoid oligomers with alpha-chiral aliphatic side chains. J Am Chem Soc (2003) 1.39
Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer. Clin Cancer Res (2007) 1.39
Oligo(N-aryl glycines): a new twist on structured peptoids. J Am Chem Soc (2008) 1.37
Free-floating ultrathin two-dimensional crystals from sequence-specific peptoid polymers. Nat Mater (2010) 1.37
The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer. Biochim Biophys Acta (2013) 1.34
Incorporation of unprotected heterocyclic side chains into peptoid oligomers via solid-phase submonomer synthesis. J Am Chem Soc (2003) 1.34
Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis. Mol Cell Biol (2004) 1.33
Involvement of the SCF complex in the control of Cdh1 degradation in S-phase. Cell Cycle (2005) 1.32
Caenorhabditis elegans decapping proteins: localization and functional analysis of Dcp1, Dcp2, and DcpS during embryogenesis. Mol Biol Cell (2005) 1.32
INTS3 controls the hSSB1-mediated DNA damage response. J Cell Biol (2009) 1.31
Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines. Proc Natl Acad Sci U S A (2011) 1.30
FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. J Cell Biol (2013) 1.28
Extreme stability of helices formed by water-soluble poly-N-substituted glycines (polypeptoids) with alpha-chiral side chains. Biopolymers (2002) 1.28
SnapShot: F box proteins I. Cell (2009) 1.27
Diverse roles of actin in C. elegans early embryogenesis. BMC Dev Biol (2007) 1.25
Two phases of astral microtubule activity during cytokinesis in C. elegans embryos. Dev Cell (2006) 1.24
Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med (2004) 1.24
Peptoid architectures: elaboration, actuation, and application. Curr Opin Chem Biol (2008) 1.24
Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Sci Signal (2012) 1.23
DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age. Dev Cell (2007) 1.22
Cell cycle, proteolysis and cancer. Curr Opin Cell Biol (2004) 1.22
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A (2012) 1.22
Experimental tests to definitively determine ubiquitylation of a substrate. Methods Enzymol (2005) 1.21