Published in Bioorg Med Chem Lett on August 09, 2006
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Prodrugs for improving tumor targetability and efficiency. Adv Drug Deliv Rev (2011) 1.00
Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers. J Am Chem Soc (2011) 0.96
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Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles. Chem Commun (Camb) (2014) 0.80
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Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide. J Am Chem Soc (2016) 0.78
Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer Cells. Theranostics (2016) 0.77
Development of a folate receptor (FR)-targeted indenoisoquinoline using a pH-sensitive N-ethoxybenzylimidazole (NEBI) bifunctional cross-linker. Bioconjug Chem (2014) 0.75
Bio-mimicking of proline-rich motif applied to carbon nanotube reveals unexpected subtleties underlying nanoparticle functionalization. Sci Rep (2014) 0.75
Brain Delivery of Drug and MRI Contrast Agent: Detection and Quantitative Determination of Brain Deposition of CPT-Glu Using LC-MS/MS and Gd-DTPA Using Magnetic Resonance Imaging. Mol Pharm (2016) 0.75
Design of new acid-activated cell-penetrating peptides for tumor drug delivery. PeerJ (2017) 0.75
PSMA-Targeted Theranostic Nanocarrier for Prostate Cancer. Theranostics (2017) 0.75
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med (2011) 7.82
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal Biochem (2005) 4.65
In vitro and in vivo two-photon luminescence imaging of single gold nanorods. Proc Natl Acad Sci U S A (2005) 3.66
Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases. Acc Chem Res (2007) 3.03
In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry. Proc Natl Acad Sci U S A (2007) 2.70
Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev (2002) 2.56
Folate receptor-mediated drug targeting: from therapeutics to diagnostics. J Pharm Sci (2005) 2.46
Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane. Proc Natl Acad Sci U S A (2005) 2.44
Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy. Am J Physiol Cell Physiol (2004) 2.16
Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol (2008) 2.01
Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo forster resonance energy transfer imaging. Langmuir (2008) 1.88
Folate-targeted therapies for cancer. J Med Chem (2010) 1.73
Folate receptor overexpression is associated with poor outcome in breast cancer. Int J Cancer (2007) 1.65
Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging. Proc Natl Acad Sci U S A (2006) 1.65
Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors. Cancer Immunol Immunother (2002) 1.63
Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential. Adv Drug Deliv Rev (2004) 1.59
Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis. Adv Drug Deliv Rev (2004) 1.58
Tumor detection using folate receptor-targeted imaging agents. Cancer Metastasis Rev (2008) 1.58
A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages. Blood (2008) 1.49
Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion. Blood (2009) 1.42
A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis. J Biol Chem (2008) 1.41
Prostate-specific membrane antigen targeted imaging and therapy of prostate cancer using a PSMA inhibitor as a homing ligand. Mol Pharm (2009) 1.36
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery. Mol Pharmacol (2004) 1.35
Quantitation of circulating tumor cells in blood samples from ovarian and prostate cancer patients using tumor-specific fluorescent ligands. Int J Cancer (2008) 1.34
Design, synthesis, and preclinical evaluation of prostate-specific membrane antigen targeted (99m)Tc-radioimaging agents. Mol Pharm (2009) 1.31
Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis. Arthritis Rheum (2002) 1.30
Regulation of membrane-cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3. Blood (2011) 1.29
Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma. Cancer Lett (2004) 1.28
Headpiece domain of dematin is required for the stability of the erythrocyte membrane. Proc Natl Acad Sci U S A (2002) 1.26
Optical imaging of metastatic tumors using a folate-targeted fluorescent probe. J Biomed Opt (2003) 1.26
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
CXCR4 expression in prostate cancer progenitor cells. PLoS One (2012) 1.25
T-cell immunity to the folate receptor alpha is prevalent in women with breast or ovarian cancer. J Clin Oncol (2006) 1.24
Mapping of glycolytic enzyme-binding sites on human erythrocyte band 3. Biochem J (2006) 1.23
Modulation of red cell glycolysis: interactions between vertebrate hemoglobins and cytoplasmic domains of band 3 red cell membrane proteins. Am J Physiol Regul Integr Comp Physiol (2004) 1.23
Identification of a critical ankyrin-binding loop on the cytoplasmic domain of erythrocyte membrane band 3 by crystal structure analysis and site-directed mutagenesis. J Biol Chem (2002) 1.23
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice. Blood (2008) 1.23
An osmotically induced cytosolic Ca2+ transient activates calcineurin signaling to mediate ion homeostasis and salt tolerance of Saccharomyces cerevisiae. J Biol Chem (2002) 1.22
Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents. Arch Pathol Lab Med (2012) 1.17
Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts. J Biol Chem (2008) 1.16
Immunohistochemical expression of folate receptor alpha in colorectal carcinoma: patterns and biological significance. Hum Pathol (2008) 1.14
Characterization of the deoxyhemoglobin binding site on human erythrocyte band 3: implications for O2 regulation of erythrocyte properties. Blood (2007) 1.13
Imaging of the diffusion of single band 3 molecules on normal and mutant erythrocytes. Blood (2009) 1.12
The effect of chemotherapy on expression of folate receptor-alpha in ovarian cancer. Cell Oncol (Dordr) (2011) 1.10
Role of band 3 in regulating metabolic flux of red blood cells. Proc Natl Acad Sci U S A (2009) 1.10
Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma. Nat Commun (2013) 1.06
Peroxiredoxin-2 expression is increased in beta-thalassemic mouse red cells but is displaced from the membrane as a marker of oxidative stress. Free Radic Biol Med (2010) 1.06
LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy. J Cell Sci (2012) 1.05
Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis. Arthritis Res Ther (2006) 1.05
Cholesterol level regulates endosome motility via Rab proteins. Biophys J (2007) 1.04
Folate receptor-targeted immunotherapy: induction of humoral and cellular immunity against hapten-decorated cancer cells. Int J Cancer (2005) 1.04
Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate. Arthritis Res Ther (2011) 1.03
Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals. Nucl Med Biol (2003) 1.03
Immunotherapy of folate receptor-expressing tumors: review of recent advances and future prospects. J Control Release (2003) 1.03
Detection of Bacillus subtilis spores using peptide-functionalized cantilever arrays. J Am Chem Soc (2006) 1.03
Strategy to prevent drug-related hypersensitivity in folate-targeted hapten immunotherapy of cancer. AAPS J (2009) 1.02
An 11-amino acid beta-hairpin loop in the cytoplasmic domain of band 3 is responsible for ankyrin binding in mouse erythrocytes. Proc Natl Acad Sci U S A (2007) 1.02
Characterization of the pH of folate receptor-containing endosomes and the rate of hydrolysis of internalized acid-labile folate-drug conjugates. J Pharmacol Exp Ther (2007) 1.01
Development of tumor-targeted near infrared probes for fluorescence guided surgery. Bioconjug Chem (2013) 1.00
Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis. Blood (2003) 1.00
Deep-tissue imaging of intramolecular fluorescence resonance energy-transfer parameters. Opt Lett (2010) 1.00
Changes in the properties of normal human red blood cells during in vivo aging. Am J Hematol (2012) 1.00
Effector-induced Syk-mediated phosphorylation in human erythrocytes. Biochim Biophys Acta (2005) 0.99
Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs. Biochim Biophys Acta (2002) 0.99
Synthesis and biological analysis of prostate-specific membrane antigen-targeted anticancer prodrugs. J Med Chem (2010) 0.98
Imaging of atherosclerosis in apoliprotein e knockout mice: targeting of a folate-conjugated radiopharmaceutical to activated macrophages. J Nucl Med (2010) 0.97
Functional folate receptor alpha is elevated in the blood of ovarian cancer patients. PLoS One (2009) 0.96
Expression of the folate receptor genes FOLR1 and FOLR3 differentiates ovarian carcinoma from breast carcinoma and malignant mesothelioma in serous effusions. Hum Pathol (2009) 0.95
Evaluation of folate conjugate uptake and transport by the choroid plexus of mice. Pharm Res (2003) 0.95
A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity. Arthritis Res Ther (2011) 0.95
Folate receptor-mediated targeting of liposomal drugs to cancer cells. Methods Enzymol (2004) 0.95
Folate receptor-α expression in resectable hepatic colorectal cancer metastases: patterns and significance. Mod Pathol (2011) 0.95
Identification of the components of a glycolytic enzyme metabolon on the human red blood cell membrane. J Biol Chem (2012) 0.93
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells. Blood (2002) 0.93
Targeting folate receptors to treat invasive urinary bladder cancer. Cancer Res (2012) 0.92
Receptor-mediated delivery of siRNAs by tethered nucleic acid base-paired interactions. RNA (2008) 0.92
Targeting of nanoparticles: folate receptor. Methods Mol Biol (2010) 0.90
Folate-targeted dinitrophenyl hapten immunotherapy: effect of linker chemistry on antitumor activity and allergic potential. Mol Pharm (2007) 0.90
Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes. J Biol Chem (2011) 0.90
Identification of contact sites between ankyrin and band 3 in the human erythrocyte membrane. Biochemistry (2012) 0.90
Immunomagnetic diffractometry for detection of diagnostic serum markers. J Am Chem Soc (2007) 0.90
Ligand-targeted delivery of small interfering RNAs to malignant cells and tissues. Ann N Y Acad Sci (2009) 0.90
Increased uptake of folate conjugates by activated macrophages in experimental hyperlipemia. Cell Tissue Res (2005) 0.89
Effect of folate-targeted nanoparticle size on their rates of penetration into solid tumors. ACS Nano (2013) 0.89
Use of folate-conjugated imaging agents to target alternatively activated macrophages in a murine model of asthma. Mol Pharm (2013) 0.89
Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate-targeted immunotherapy in hapten-immunized mice. Mol Cancer Ther (2006) 0.89
Protein kinase C activation induces phosphatidylserine exposure on red blood cells. Biochemistry (2002) 0.89
Depletion of folate-receptor-positive macrophages leads to alleviation of symptoms and prolonged survival in two murine models of systemic lupus erythematosus. Mol Pharm (2007) 0.88
Bishydrazide glycoconjugates for lectin recognition and capture of bacterial pathogens. Bioconjug Chem (2010) 0.87
Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis. Arthritis Res Ther (2013) 0.87
Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte membrane. Biochem J (2013) 0.87
Detection of folate binding protein with enhanced sensitivity using a functionalized quartz crystal microbalance sensor. Anal Chem (2006) 0.87