Published in RNA on January 24, 2008
Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle (2009) 3.60
Engineering RNA for targeted siRNA delivery and medical application. Adv Drug Deliv Rev (2010) 1.32
Targeted delivery systems for oligonucleotide therapeutics. AAPS J (2009) 1.19
Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple tumor cells. Mol Biosyst (2009) 0.96
Site-specific antibody-polymer conjugates for siRNA delivery. J Am Chem Soc (2013) 0.87
Vasopressin V2R-targeting peptide carrier mediates siRNA delivery into collecting duct cells. PLoS One (2012) 0.77
New type of BACE1 siRNA delivery to cells. Med Sci Monit (2014) 0.75
Activation of the interferon system by short-interfering RNAs. Nat Cell Biol (2003) 8.63
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol (2005) 6.40
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat Biotechnol (2006) 6.30
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal Biochem (2005) 4.65
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res (2005) 3.81
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res (2004) 3.03
Aptamer mediated siRNA delivery. Nucleic Acids Res (2006) 2.77
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3. J Immunol (2004) 2.42
RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature. Drug Resist Updat (2005) 1.98
Integrin alpha v beta 3 as a therapeutic target for blocking tumor-induced angiogenesis. Curr Drug Targets (2003) 1.70
Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging. Proc Natl Acad Sci U S A (2006) 1.65
Construction of folate-conjugated pRNA of bacteriophage phi29 DNA packaging motor for delivery of chimeric siRNA to nasopharyngeal carcinoma cells. Gene Ther (2006) 1.48
Folate-mediated targeting: from diagnostics to drug and gene delivery. Drug Discov Today (2001) 1.36
Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma. Cancer Lett (2004) 1.28
Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies. Bioconjug Chem (2003) 1.13
Arg-Gly-Asp peptide increases endothelial hydraulic conductivity: comparison with thrombin response. Am J Physiol (1995) 1.09
Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis. Arthritis Res Ther (2006) 1.05
Combination of integrin siRNA and irradiation for breast cancer therapy. Biochem Biophys Res Commun (2006) 0.85
The inhibitor of apoptosis (IAP) survivin is expressed in human testicular germ cell tumors and normal testes. Cancer Lett (2004) 0.84
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med (2011) 7.82
Diagnostic markers for early detection of ovarian cancer. Clin Cancer Res (2008) 6.47
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal Biochem (2005) 4.65
Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data. Bioinformatics (2003) 3.78
In vitro and in vivo two-photon luminescence imaging of single gold nanorods. Proc Natl Acad Sci U S A (2005) 3.66
Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle (2009) 3.60
A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells. Science (2008) 3.52
Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prev Res (Phila) (2011) 3.33
The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell (2013) 3.27
TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. Cancer Res (2006) 3.21
A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer. Cancer Prev Res (Phila) (2011) 3.03
In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry. Proc Natl Acad Sci U S A (2007) 2.70
Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev (2002) 2.56
Folate receptor-mediated drug targeting: from therapeutics to diagnostics. J Pharm Sci (2005) 2.46
Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane. Proc Natl Acad Sci U S A (2005) 2.44
Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA (2009) 2.30
Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays. Proc Natl Acad Sci U S A (2007) 2.22
Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy. Am J Physiol Cell Physiol (2004) 2.16
Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol (2008) 2.01
Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Res (2009) 1.93
Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells (2011) 1.90
Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo forster resonance energy transfer imaging. Langmuir (2008) 1.88
Stem-like ovarian cancer cells can serve as tumor vascular progenitors. Stem Cells (2009) 1.84
Uterine DCs are crucial for decidua formation during embryo implantation in mice. J Clin Invest (2008) 1.82
A novel immortalized human endometrial stromal cell line with normal progestational response. Endocrinology (2004) 1.76
Folate-targeted therapies for cancer. J Med Chem (2010) 1.73
Low-grade endometrial stromal sarcoma: hormonal aspects. Gynecol Oncol (2003) 1.65
Inflammation, cancer and chemoresistance: taking advantage of the toll-like receptor signaling pathway. Am J Reprod Immunol (2007) 1.65
Phenoxodiol--an isoflavone analog--induces apoptosis in chemoresistant ovarian cancer cells. Oncogene (2003) 1.65
Folate receptor overexpression is associated with poor outcome in breast cancer. Int J Cancer (2007) 1.65
Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging. Proc Natl Acad Sci U S A (2006) 1.65
Divergent trophoblast responses to bacterial products mediated by TLRs. J Immunol (2004) 1.64
Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors. Cancer Immunol Immunother (2002) 1.63
Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Proc Natl Acad Sci U S A (2011) 1.60
Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential. Adv Drug Deliv Rev (2004) 1.59
Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis. Adv Drug Deliv Rev (2004) 1.58
Tumor detection using folate receptor-targeted imaging agents. Cancer Metastasis Rev (2008) 1.58
Epithelial ovarian cancer cells secrete functional Fas ligand. Cancer Res (2003) 1.52
Macrophages and apoptotic cell clearance during pregnancy. Am J Reprod Immunol (2004) 1.51
A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages. Blood (2008) 1.49
Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis. Am J Obstet Gynecol (2004) 1.49
7-(O)-Carboxymethyl daidzein conjugated to N-t-Boc-hexylenediamine: a novel compound capable of inducing cell death in epithelial ovarian cancer stem cells. Cancer Biol Ther (2009) 1.48
Local injury of the endometrium induces an inflammatory response that promotes successful implantation. Fertil Steril (2010) 1.46
Safe conception for HIV-discordant couples: insemination with processed semen from the HIV-infected partner. Am J Obstet Gynecol (2013) 1.45
ERβ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. Cancer Biol Ther (2011) 1.45
Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion. Blood (2009) 1.42
A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis. J Biol Chem (2008) 1.41
Inflammation and implantation. Am J Reprod Immunol (2010) 1.41
Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages. Am J Reprod Immunol (2014) 1.40
Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor. J Immunol (2010) 1.39
The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy. Endocr Rev (2005) 1.37
Prostate-specific membrane antigen targeted imaging and therapy of prostate cancer using a PSMA inhibitor as a homing ligand. Mol Pharm (2009) 1.36
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery. Mol Pharmacol (2004) 1.35
Quantitation of circulating tumor cells in blood samples from ovarian and prostate cancer patients using tumor-specific fluorescent ligands. Int J Cancer (2008) 1.34
Design, synthesis, and preclinical evaluation of prostate-specific membrane antigen targeted (99m)Tc-radioimaging agents. Mol Pharm (2009) 1.31
Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element. Nucleic Acids Res (2009) 1.31
Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis. Arthritis Rheum (2002) 1.30
Regulation of membrane-cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3. Blood (2011) 1.29
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proc Natl Acad Sci U S A (2011) 1.29
Activation of TLR3 in the trophoblast is associated with preterm delivery. Am J Reprod Immunol (2009) 1.29
Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells. Mol Cancer Ther (2011) 1.28
Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma. Cancer Lett (2004) 1.28
Molecular mechanism of phenoxodiol-induced apoptosis in ovarian carcinoma cells. Cancer (2006) 1.27
A role for TLRs in the regulation of immune cell migration by first trimester trophoblast cells. J Immunol (2005) 1.27
Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Blood (2003) 1.26
Optical imaging of metastatic tumors using a folate-targeted fluorescent probe. J Biomed Opt (2003) 1.26
Headpiece domain of dematin is required for the stability of the erythrocyte membrane. Proc Natl Acad Sci U S A (2002) 1.26
Toll-like receptor 4: a potential link between "danger signals," the innate immune system, and preeclampsia? Am J Obstet Gynecol (2005) 1.26
First trimester trophoblast cells secrete Fas ligand which induces immune cell apoptosis. Mol Hum Reprod (2004) 1.25
Placental apoptosis in health and disease. Am J Reprod Immunol (2010) 1.25
Toll-like receptors at the maternal-fetal interface in normal pregnancy and pregnancy disorders. Am J Reprod Immunol (2010) 1.25
T-cell immunity to the folate receptor alpha is prevalent in women with breast or ovarian cancer. J Clin Oncol (2006) 1.24
Mapping of glycolytic enzyme-binding sites on human erythrocyte band 3. Biochem J (2006) 1.23
Modulation of red cell glycolysis: interactions between vertebrate hemoglobins and cytoplasmic domains of band 3 red cell membrane proteins. Am J Physiol Regul Integr Comp Physiol (2004) 1.23
Identification of a critical ankyrin-binding loop on the cytoplasmic domain of erythrocyte membrane band 3 by crystal structure analysis and site-directed mutagenesis. J Biol Chem (2002) 1.23
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice. Blood (2008) 1.23
An osmotically induced cytosolic Ca2+ transient activates calcineurin signaling to mediate ion homeostasis and salt tolerance of Saccharomyces cerevisiae. J Biol Chem (2002) 1.22
Placental viral infection sensitizes to endotoxin-induced pre-term labor: a double hit hypothesis. Am J Reprod Immunol (2010) 1.21
The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization. J Transl Med (2007) 1.21
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes. Nucleic Acids Res (2011) 1.20
Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer. Am J Pathol (2009) 1.20
Resistance of ovarian carcinoma cells to docetaxel is XIAP dependent and reversible by phenoxodiol. Oncol Res (2004) 1.20
A novel three-dimensional in vitro system to study trophoblast-endothelium cell interactions. Am J Reprod Immunol (2007) 1.20
Lin28 regulates HER2 and promotes malignancy through multiple mechanisms. Cell Cycle (2012) 1.17
Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents. Arch Pathol Lab Med (2012) 1.17
Viral infections during pregnancy. Am J Reprod Immunol (2015) 1.17
Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts. J Biol Chem (2008) 1.16
Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells. Proc Natl Acad Sci U S A (2007) 1.15
Prevalence of epithelial ovarian cancer stem cells correlates with recurrence in early-stage ovarian cancer. J Oncol (2011) 1.15
Immunohistochemical expression of folate receptor alpha in colorectal carcinoma: patterns and biological significance. Hum Pathol (2008) 1.14
Characterization of the deoxyhemoglobin binding site on human erythrocyte band 3: implications for O2 regulation of erythrocyte properties. Blood (2007) 1.13
Biological significance of prolactin in gynecologic cancers. Cancer Res (2009) 1.13
Synthesis and activity of a folate peptide camptothecin prodrug. Bioorg Med Chem Lett (2006) 1.12
TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence. Cell Cycle (2013) 1.12
Imaging of the diffusion of single band 3 molecules on normal and mutant erythrocytes. Blood (2009) 1.12
Inhibition of Aurora-A kinase induces cell cycle arrest in epithelial ovarian cancer stem cells by affecting NFĸB pathway. Cell Cycle (2011) 1.11
The effect of chemotherapy on expression of folate receptor-alpha in ovarian cancer. Cell Oncol (Dordr) (2011) 1.10
ERCC1 genotype and phenotype in epithelial ovarian cancer identify patients likely to benefit from paclitaxel treatment in addition to platinum-based therapy. J Clin Oncol (2007) 1.10