Published in Transplantation on August 15, 2006
Coagulation dysregulation as a barrier to xenotransplantation in the primate. Transpl Immunol (2008) 1.17
Clinical lung xenotransplantation--what donor genetic modifications may be necessary? Xenotransplantation (2012) 1.16
Current status of xenotransplantation and prospects for clinical application. Xenotransplantation (2009) 1.15
Pig-to-monkey islet xenotransplantation using multi-transgenic pigs. Am J Transplant (2014) 0.96
Controlling coagulation dysregulation in xenotransplantation. Curr Opin Organ Transplant (2011) 0.93
Inflammatory response in islet transplantation. Int J Endocrinol (2014) 0.91
Chemoselective immobilization of peptides on abiotic and cell surfaces at controlled densities. Langmuir (2010) 0.87
Xenotransplantation as a model of integrated, multidisciplinary research. Organogenesis (2009) 0.86
The protective effects of CD39 overexpression in multiple low-dose streptozotocin-induced diabetes in mice. Diabetes (2013) 0.84
Glucose metabolism in pigs expressing human genes under an insulin promoter. Xenotransplantation (2014) 0.82
Thrombosis and inflammation in intraportal islet transplantation: a review of pathophysiology and emerging therapeutics. J Diabetes Sci Technol (2008) 0.82
Immunobiology of liver xenotransplantation. Expert Rev Clin Immunol (2012) 0.81
The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes. J Biomed Biotechnol (2012) 0.78
Unlocking the Potential of Purinergic Signaling in Transplantation. Am J Transplant (2016) 0.77
Immune modulation in xenotransplantation. Arch Immunol Ther Exp (Warsz) (2014) 0.76
CD39 overexpression does not attenuate renal fibrosis in the unilateral ureteric obstructive model of chronic kidney disease. Purinergic Signal (2016) 0.75
Use of genetically-engineered pig donors in islet transplantation. World J Transplant (2015) 0.75
Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro. PLoS One (2015) 0.75
Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas. J Diabetes Res (2015) 0.75
Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes. Transgenic Res (2016) 0.75
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 10.00
Purinergic signaling during inflammation. N Engl J Med (2012) 4.08
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med (2003) 3.71
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med (2004) 3.58
CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness. Nat Med (2002) 3.18
Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood (2004) 2.80
Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis. Hepatology (2014) 2.29
ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res (2006) 2.23
CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury. Circulation (2007) 2.09
Coagulopathy in cirrhosis - the role of the platelet in hemostasis. J Hepatol (2013) 2.01
Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein. J Immunol (2005) 1.92
Effective treatment of Waldenström macroglobulinemia associated pure red cell aplasia with standard antilymphomatous chemotherapy. Leuk Lymphoma (2013) 1.92
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury. FASEB J (2007) 1.84
Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity (2012) 1.82
Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts. J Am Soc Nephrol (2005) 1.79
Central role of Sp1-regulated CD39 in hypoxia/ischemia protection. Blood (2008) 1.79
From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease. Proc Natl Acad Sci U S A (2009) 1.75
The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells. Cancer Res (2008) 1.71
CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice. Gastroenterology (2010) 1.69
CD39 and control of cellular immune responses. Purinergic Signal (2007) 1.68
Promotion of liver regeneration by natural killer cells in a murine model is dependent on extracellular adenosine triphosphate phosphohydrolysis. Hepatology (2013) 1.66
Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut (2012) 1.65
High incidence of Pneumocystis jirovecii pneumonia in patients receiving biweekly rituximab and cyclophosphamide, adriamycin, vincristine, and prednisone. Leuk Lymphoma (2010) 1.64
First quantification of alpha-Gal epitope in current glutaraldehyde-fixed heart valve bioprostheses. Xenotransplantation (2013) 1.62
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation. J Clin Invest (2004) 1.61
Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma. Hepatology (2013) 1.59
alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation (2005) 1.56
Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway. FASEB J (2013) 1.51
IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol (2013) 1.50
Carbon monoxide orchestrates a protective response through PPARgamma. Immunity (2006) 1.47
Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity. Adv Pharmacol (2011) 1.45
HGF and SDF-1-mediated mobilization of CD133+ BMSC for hepatic regeneration following extensive liver resection. Liver Int (2013) 1.42
Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation. Development (2006) 1.41
Gal mismatch alone causes skin graft rejection in mice. Transplantation (2002) 1.40
A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis. Leuk Lymphoma (2012) 1.39
Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways. Thromb Haemost (2005) 1.38
Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8. Biochemistry (2004) 1.36
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol (2008) 1.36
The ecto-nucleoside triphosphate diphosphohydrolase NTPDase2/CD39L1 is expressed in a novel functional compartment within the liver. Hepatology (2002) 1.34
Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate. Neoplasia (2011) 1.34
Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice. Am J Pathol (2007) 1.32
Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. Eur J Neurosci (2003) 1.31
SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning. J Immunol (2010) 1.31
Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine. J Biol Chem (2008) 1.31
Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury. Thromb Haemost (2004) 1.31
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis. Hepatology (2008) 1.27
Predictors of endoscopic inflammation in patients with ulcerative colitis in clinical remission. Inflamm Bowel Dis (2013) 1.27
Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol (2004) 1.27
Ecto-nucleotidases of the CD39/NTPDase family modulate platelet activation and thrombus formation: Potential as therapeutic targets. Blood Cells Mol Dis (2006) 1.24
The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism. Front Biosci (2008) 1.24
Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease. Am J Physiol Gastrointest Liver Physiol (2006) 1.19
The symptom burden of patients with hematological malignancy: a cross-sectional observational study. J Pain Symptom Manage (2011) 1.18
Deletion of cd39/entpd1 results in hepatic insulin resistance. Diabetes (2008) 1.18
Purinergic signaling during inflammation. N Engl J Med (2013) 1.17
A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila. Cell Microbiol (2007) 1.17
Clinical lung xenotransplantation--what donor genetic modifications may be necessary? Xenotransplantation (2012) 1.16
Regulated catalysis of extracellular nucleotides by vascular CD39/ENTPD1 is required for liver regeneration. Gastroenterology (2008) 1.15
Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling. Am J Physiol Renal Physiol (2005) 1.14
Association of the ecto-ATPase NTPDase2 with glial cells of the peripheral nervous system. Glia (2004) 1.12
Overexpression of glutathione peroxidase with two isoforms of superoxide dismutase protects mouse islets from oxidative injury and improves islet graft function. Diabetes (2005) 1.11
P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice. Am J Physiol Gastrointest Liver Physiol (2012) 1.10
NTPDase1 governs P2X7-dependent functions in murine macrophages. Eur J Immunol (2010) 1.09
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death. Blood (2011) 1.09
Deletion of CD39 on natural killer cells attenuates hepatic ischemia/reperfusion injury in mice. Hepatology (2010) 1.09
The ectonucleotidase cd39/ENTPDase1 modulates purinergic-mediated microglial migration. Glia (2008) 1.08
Expression and distribution of ectonucleotidases in mouse urinary bladder. PLoS One (2011) 1.08
Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity. Transplantation (2004) 1.07
Extracellular nucleotides as negative modulators of immunity. Curr Opin Pharmacol (2009) 1.07
Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on host-pathogen interactions. Microbiol Mol Biol Rev (2008) 1.07
Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states. J Mol Med (Berl) (2013) 1.06
TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood (2013) 1.06
Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer. Purinergic Signal (2011) 1.06
RanBPM associates with CD39 and modulates ecto-nucleotidase activity. Biochem J (2006) 1.05
P2X7 integrates PI3K/AKT and AMPK-PRAS40-mTOR signaling pathways to mediate tumor cell death. PLoS One (2013) 1.03
Role of the ectonucleotidase NTPDase2 in taste bud function. Proc Natl Acad Sci U S A (2013) 1.03
The vascular ectonucleotidase ENTPD1 is a novel renoprotective factor in diabetic nephropathy. Diabetes (2007) 1.02
Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis. Inflamm Bowel Dis (2005) 1.02
Production of homozygous alpha-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer. Xenotransplantation (2007) 1.02
Transgenic swine: expression of human CD39 protects against myocardial injury. J Mol Cell Cardiol (2012) 1.02
CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation. Br J Haematol (2008) 1.00
Disordered pancreatic inflammatory responses and inhibition of fibrosis in CD39-null mice. Gastroenterology (2007) 1.00
Making sense of regulatory T cell suppressive function. Semin Immunol (2011) 1.00
Inhibition of interleukin-17 promotes differentiation of CD25⁻ cells into stable T regulatory cells in patients with autoimmune hepatitis. Gastroenterology (2012) 0.99
GalT-KO pigs: is the cup half empty or half full? Transplantation (2007) 0.99
O-linked glycosylation and functional incompatibility of porcine von Willebrand factor for human platelet GPIb receptors. Xenotransplantation (2005) 0.99
Building on the GalKO platform. Transplantation (2007) 0.97
Enhanced expression of glutathione peroxidase protects islet beta cells from hypoxia-reoxygenation. Xenotransplantation (2004) 0.96
Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury. J Mol Cell Cardiol (2011) 0.95
The impact of purinergic signaling on renal ischemia-reperfusion injury. Transplantation (2008) 0.95