Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression.

PubWeight™: 1.90‹?› | Rank: Top 3%

🔗 View Article (PMC 1785074)

Published in Blood on August 29, 2006

Authors

Stuart T Fraser1, Joan Isern, Margaret H Baron

Author Affiliations

1: Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.

Articles citing this

Developmental and species-divergent globin switching are driven by BCL11A. Nature (2009) 3.49

Biologic properties and enucleation of red blood cells from human embryonic stem cells. Blood (2008) 3.01

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells. Genome Res (2010) 2.02

Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus. Blood (2010) 1.91

Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo. Blood (2011) 1.79

Advances in the understanding of haemoglobin switching. Br J Haematol (2010) 1.74

Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus. Blood (2007) 1.68

Ontogenetic regulation of leukocyte recruitment in mouse yolk sac vessels. Blood (2013) 1.45

Primitive and definitive erythropoiesis in mammals. Front Physiol (2014) 1.34

The erythroblastic island. Curr Top Dev Biol (2008) 1.32

The fetal liver is a niche for maturation of primitive erythroid cells. Proc Natl Acad Sci U S A (2008) 1.24

Erythroblast enucleation. Stem Cells Int (2011) 1.21

EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis. Blood (2007) 1.11

Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells. Blood Cells Mol Dis (2013) 1.11

The embryonic origins of erythropoiesis in mammals. Blood (2012) 1.09

The first trimester human placenta is a site for terminal maturation of primitive erythroid cells. Blood (2010) 1.09

Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150. Stem Cells (2009) 1.06

Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf. Blood (2010) 1.03

Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells (2012) 1.03

Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding. J Biol Chem (2011) 1.01

The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo. Cell Death Differ (2012) 0.99

Erythropoiesis: development and differentiation. Cold Spring Harb Perspect Med (2013) 0.98

The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood (2013) 0.96

Erythropoietin critically regulates the terminal maturation of murine and human primitive erythroblasts. Haematologica (2013) 0.96

A critical role for endoglin in the emergence of blood during embryonic development. Blood (2012) 0.95

Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis. Mol Cell Biol (2012) 0.93

Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Mol Ther (2013) 0.90

Lymphoid progenitor emergence in the murine embryo and yolk sac precedes stem cell detection. Stem Cells Dev (2014) 0.89

Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun (2015) 0.87

Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development. Adv Hematol (2011) 0.86

RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. Blood (2010) 0.84

Developmental niches for embryonic erythroid cells. Blood Cells Mol Dis (2010) 0.84

Erythroid development in the mammalian embryo. Blood Cells Mol Dis (2013) 0.84

Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ mice. Stem Cells Int (2011) 0.82

Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins. Br J Haematol (2014) 0.81

Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality. J Immunol (2015) 0.81

The erythroblastic island as an emerging paradigm in the anemia of inflammation. Immunol Res (2015) 0.80

Development of membrane mechanical function during terminal stages of primitive erythropoiesis in mice. Exp Hematol (2012) 0.80

Embryonic regulation of the mouse hematopoietic niche. ScientificWorldJournal (2011) 0.80

Making Blood: The Haematopoietic Niche throughout Ontogeny. Stem Cells Int (2015) 0.80

Development and differentiation of the erythroid lineage in mammals. Dev Comp Immunol (2015) 0.80

Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Proc Natl Acad Sci U S A (2015) 0.79

Vasculogenic and hematopoietic cellular progenitors are scattered within the prenatal mouse heart. Histochem Cell Biol (2014) 0.79

The modern primitives: applying new technological approaches to explore the biology of the earliest red blood cells. ISRN Hematol (2013) 0.79

Evidence for a bigenic chromatin subdomain in regulation of the fetal-to-adult hemoglobin switch. Mol Cell Biol (2008) 0.78

A dual reporter mouse model of the human β-globin locus: applications and limitations. PLoS One (2012) 0.78

Concise Review: early embryonic erythropoiesis: not so primitive after all. Stem Cells (2013) 0.78

FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis. Arterioscler Thromb Vasc Biol (2015) 0.78

Rapid detection of haemotropic mycoplasma infection of feline erythrocytes using a novel flow cytometric approach. Parasit Vectors (2013) 0.77

Cells with surface expression of CD133(high)CD71(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. Stem Cell Res (2015) 0.77

Pregnancy-secreted Acid phosphatase, uteroferrin, enhances fetal erythropoiesis. Endocrinology (2014) 0.76

Studies of Hematopoietic Cell Differentiation with a Ratiometric and Reversible Sensor of Mitochondrial Reactive Oxygen Species. Antioxid Redox Signal (2016) 0.76

Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice. Genesis (2013) 0.75

Interaction of the Macrophage and Primitive Erythroid Lineages in the Mammalian Embryo. Front Immunol (2017) 0.75

Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation. Blood (2015) 0.75

Generation of transgenic mouse fluorescent reporter lines for studying hematopoietic development. Methods Mol Biol (2014) 0.75

Animal models of β-hemoglobinopathies: utility and limitations. J Blood Med (2016) 0.75

Regulation of the embryonic erythropoietic niche: a future perspective. Blood Res (2017) 0.75

Delayed hemoglobin switching and perinatal neocytolysis in mice with gain-of-function erythropoietin receptor. J Mol Med (Berl) (2015) 0.75

The Ets2 repressor factor (Erf) is required for effective primitive and definitive hematopoiesis. Mol Cell Biol (2017) 0.75

Primitive erythrocytes are generated from hemogenic endothelial cells. Sci Rep (2017) 0.75

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating. Sci Rep (2017) 0.75

Articles cited by this

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature (1995) 15.15

A common precursor for hematopoietic and endothelial cells. Development (1998) 6.58

Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development (1999) 4.93

Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system. Blood (2003) 4.91

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell (1999) 4.69

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell (1996) 4.35

Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature (2004) 4.20

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc Natl Acad Sci U S A (1995) 3.47

The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. Br J Haematol (2000) 3.31

Molecular analysis of the human beta-globin locus activation region. Proc Natl Acad Sci U S A (1989) 3.17

CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development (2003) 3.09

Rapid reprogramming of globin gene expression in transient heterokaryons. Cell (1986) 2.90

Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature (2005) 2.45

Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development (2001) 2.33

The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins. J Cell Biol (1990) 2.32

Molecular mechanisms of vasculogenesis and embryonic angiogenesis. J Cell Physiol (1997) 2.27

Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis. Blood (2004) 2.13

"Maturational" globin switching in primary primitive erythroid cells. Blood (2005) 2.04

Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture. Genesis (2002) 1.99

Measuring hemodynamic changes during mammalian development. Am J Physiol Heart Circ Physiol (2004) 1.98

A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1. Development (2000) 1.86

Yolk-sac hematopoiesis: the first blood cells of mouse and man. Exp Hematol (2001) 1.83

Circulation is established in a stepwise pattern in the mammalian embryo. Blood (2002) 1.73

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro. Blood (2002) 1.72

Development of the mouse hematopoietic system. I. Types of hemoglobin produced in embryonic yolk sac and liver. Dev Biol (1968) 1.72

New insights into erythropoiesis. Curr Opin Hematol (2002) 1.69

Using a histone yellow fluorescent protein fusion for tagging and tracking endothelial cells in ES cells and mice. Genesis (2005) 1.69

Molecular changes in the membranes of mouse erythroid cells accompanying differentiation. Cell (1979) 1.66

Expression cloning of a cDNA encoding M1/69-J11d heat-stable antigens. J Immunol (1990) 1.64

Hematopoiesis in the yolk sac: more than meets the eye. Exp Hematol (2005) 1.63

Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis. Proc Natl Acad Sci U S A (2001) 1.56

Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity. Blood (2003) 1.52

Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo. Immunity (1999) 1.51

PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors. Blood (2004) 1.47

Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development (1998) 1.45

Blood island formation: longstanding observations and modern interpretations. Exp Hematol (2005) 1.44

Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proc Natl Acad Sci U S A (1999) 1.42

The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation. Blood (2001) 1.39

Embryonic origins of mammalian hematopoiesis. Exp Hematol (2003) 1.36

Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans. Blood (1990) 1.27

AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation. Blood (2005) 1.25

Characterization of the murine heat-stable antigen: an hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies. Eur J Immunol (1990) 1.21

Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins. Blood (2005) 1.15

Integrin expression profiles during erythroid differentiation. Blood (1992) 1.14

Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo. Proc Natl Acad Sci U S A (2005) 1.12

Expression and function of c-Kit in fetal hemopoietic progenitor cells: transition from the early c-Kit-independent to the late c-Kit-dependent wave of hemopoiesis in the murine embryo. Development (1993) 1.07

Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements. Mol Cell Biol (1993) 1.04

Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor. Blood (2002) 1.02

Ultrastructural changes in mouse yolk sac associated with the initiation of vitelline circulation. Anat Rec (1971) 1.01

K-Ras is essential for normal fetal liver erythropoiesis. Blood (2005) 1.01

Changes in erythroid membrane proteins during erythropoietin-mediated terminal differentiation. J Cell Physiol (1987) 1.00

The Rb tumor suppressor in stress responses and hematopoietic homeostasis. Cell Cycle (2005) 0.97

Dynamic in vivo imaging of mammalian hematovascular development using whole embryo culture. Methods Mol Med (2005) 0.95

A novel cell permeant and far red-fluorescing DNA probe, DRAQ5, for blood cell discrimination by flow cytometry. J Immunol Methods (1999) 0.95

Expression and function of integrins on hematopoietic progenitor cells. Acta Haematol (1997) 0.95

Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. Blood (2001) 0.95

A complex linkage in the developmental pathway of endothelial and hematopoietic cells. Curr Opin Cell Biol (2001) 0.94

DRAQ5-based DNA content analysis of hematolymphoid cell subpopulations discriminated by surface antigens and light scatter properties. Cytometry B Clin Cytom (2004) 0.94

Red blood cell surface adhesion molecules: their possible roles in normal human physiology and disease. Semin Hematol (2000) 0.91

Early patterning of the mouse embryo: implications for hematopoietic commitment and differentiation. Exp Hematol (2005) 0.90

Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia. Blood (1995) 0.90

CD44 isoforms in normal and leukemic hematopoiesis. Exp Hematol (1999) 0.89

Developmental relationship between hematopoietic and endothelial cells. Immunol Res (2005) 0.87

Distribution of actin, myosin, and spectrin during enucleation in erythroid cells of hamster embryo. Cell Motil Cytoskeleton (1996) 0.85

Enucleation eliminates a differentiation-specific surface marker from normal and leukemic murine erythroid cells. Exp Cell Res (1982) 0.83

On the kinetics of erythroid cell differentiation in fetal mice. II. DNA and hemoglobin measurements of individual erythroblasts during gestation. J Cell Physiol (1973) 0.78

Hemoglobin switching and modulation: genes, cells, and signals. Curr Opin Hematol (2002) 0.77

Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation. Endocrinology (1995) 0.77

Articles by these authors

Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo. Blood (2011) 1.79

Using a histone yellow fluorescent protein fusion for tagging and tracking endothelial cells in ES cells and mice. Genesis (2005) 1.69

Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells. Proc Natl Acad Sci U S A (2007) 1.42

A membrane associated mCherry fluorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development. Anat Rec (Hoboken) (2009) 1.33

Tg(Afp-GFP) expression marks primitive and definitive endoderm lineages during mouse development. Dev Dyn (2006) 1.30

The fetal liver is a niche for maturation of primitive erythroid cells. Proc Natl Acad Sci U S A (2008) 1.24

Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci U S A (2007) 1.19

The embryonic origins of erythropoiesis in mammals. Blood (2012) 1.09

Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf. Blood (2010) 1.03

BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity. Dev Biol (2011) 1.01

Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood (2006) 0.98

Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Dev Dyn (2003) 0.97

Bone morphogenetic proteins in vertebrate hematopoietic development. J Cell Biochem (2004) 0.96

Dynamic in vivo imaging of mammalian hematovascular development using whole embryo culture. Methods Mol Med (2005) 0.95

Use of transgenic fluorescent reporter mouse lines to monitor hematopoietic and erythroid development during embryogenesis. Methods Enzymol (2010) 0.85

FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis. Am J Hematol (2014) 0.85

Embryonic fates for extraembryonic lineages: New perspectives. J Cell Biochem (2009) 0.84

Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene (2002) 0.84

Developmental niches for embryonic erythroid cells. Blood Cells Mol Dis (2010) 0.84

Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells (2014) 0.83

Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells. Stem Cells (2009) 0.81

A conditional mutant allele for analysis of Mixl1 function in the mouse. Genesis (2014) 0.75

Generation of transgenic mouse fluorescent reporter lines for studying hematopoietic development. Methods Mol Biol (2014) 0.75

Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice. Genesis (2013) 0.75

Sex steroid regulation and identification of different transcription units of the SA gene in mouse kidney. J Endocrinol (2004) 0.75