Published in Blood on February 15, 2012
Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells (2012) 1.03
Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood (2013) 0.97
Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility. Epigenetics Chromatin (2015) 0.97
Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver. Blood (2013) 0.97
TMEM14C is required for erythroid mitochondrial heme metabolism. J Clin Invest (2014) 0.96
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin. Science (2016) 0.89
MicroRNAs in hematopoietic development. BMC Immunol (2014) 0.87
Erythroid development in the mammalian embryo. Blood Cells Mol Dis (2013) 0.84
The erythroblastic island as an emerging paradigm in the anemia of inflammation. Immunol Res (2015) 0.80
Development and differentiation of the erythroid lineage in mammals. Dev Comp Immunol (2015) 0.80
Making Blood: The Haematopoietic Niche throughout Ontogeny. Stem Cells Int (2015) 0.80
Phylogenetic and Ontogenetic View of Erythroblastic Islands. Biomed Res Int (2015) 0.79
Concise review: stem cell-based approaches to red blood cell production for transfusion. Stem Cells Transl Med (2013) 0.79
The modern primitives: applying new technological approaches to explore the biology of the earliest red blood cells. ISRN Hematol (2013) 0.79
Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Proc Natl Acad Sci U S A (2015) 0.79
Concise Review: early embryonic erythropoiesis: not so primitive after all. Stem Cells (2013) 0.78
Manufacturing blood ex vivo: a futuristic approach to deal with the supply and safety concerns. Front Cell Dev Biol (2014) 0.78
Common developmental pathway for primitive erythrocytes and multipotent hematopoietic progenitors in early mouse development. Stem Cell Reports (2013) 0.77
Epigenetics of hematopoiesis and hematological malignancies. Genes Dev (2016) 0.77
Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil. Front Pediatr (2017) 0.76
Maternal exposure to diluted diesel engine exhaust alters placental function and induces intergenerational effects in rabbits. Part Fibre Toxicol (2016) 0.76
A System to Study Aneuploidy In Vivo. Cold Spring Harb Symp Quant Biol (2016) 0.76
Studies of Hematopoietic Cell Differentiation with a Ratiometric and Reversible Sensor of Mitochondrial Reactive Oxygen Species. Antioxid Redox Signal (2016) 0.76
The expression of embryonic globin mRNA in a severely anemic mouse model induced by treatment with nitrogen-containing bisphosphonate. BMC Hematol (2016) 0.76
Animal models of β-hemoglobinopathies: utility and limitations. J Blood Med (2016) 0.75
Generation of transgenic mouse fluorescent reporter lines for studying hematopoietic development. Methods Mol Biol (2014) 0.75
Regulation of the embryonic erythropoietic niche: a future perspective. Blood Res (2017) 0.75
What do we know about the participation of hematopoietic stem cells in hematopoiesis? F1000Res (2015) 0.75
Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice. Genesis (2013) 0.75
Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos. Development (2016) 0.75
Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation. Blood (2015) 0.75
Primitive erythrocytes are generated from hemogenic endothelial cells. Sci Rep (2017) 0.75
Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science (2009) 49.82
Hematopoiesis: an evolving paradigm for stem cell biology. Cell (2008) 11.95
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell (2008) 10.34
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell (1996) 9.74
A common precursor for hematopoietic and endothelial cells. Development (1998) 6.58
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science (2010) 6.38
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci U S A (1996) 6.29
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell (1991) 6.14
Forcing cells to change lineages. Nature (2009) 5.99
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell (2010) 5.05
Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature (1995) 4.97
Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development (1999) 4.93
Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system. Blood (2003) 4.91
Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature (1995) 4.80
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell (1995) 4.73
Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature (2009) 4.32
Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature (2004) 4.20
Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development (1995) 4.05
Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat Immunol (2008) 4.04
Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell (2009) 3.96
The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage. Nature (2009) 3.88
Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells. Nat Biotechnol (2004) 3.76
TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev Biol (1996) 3.29
Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice. EMBO J (2001) 3.24
CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development (2003) 3.09
Erythroblastic islands: niches for erythropoiesis. Blood (2008) 2.93
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development (2005) 2.91
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol (2009) 2.86
Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood. Cell Stem Cell (2008) 2.77
Ontogeny of the hematopoietic system. Annu Rev Immunol (2007) 2.55
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet (2010) 2.50
The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation. Genes Dev (2010) 2.47
The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo. Development (1999) 2.45
Hematopoietic cytokines. Blood (2008) 2.45
Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature (2005) 2.45
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands. Dev Cell (2006) 2.45
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood (2011) 2.42
KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching. Nat Genet (2010) 2.39
Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development (2001) 2.33
A global role for EKLF in definitive and primitive erythropoiesis. Blood (2005) 2.24
Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev (1996) 2.18
Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis. Blood (2004) 2.13
The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol (2005) 2.11
"Maturational" globin switching in primary primitive erythroid cells. Blood (2005) 2.04
Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. Blood (2000) 1.93
A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse. Anat Rec (1971) 1.93
The multifunctional role of EKLF/KLF1 during erythropoiesis. Blood (2011) 1.93
Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus. Blood (2010) 1.91
Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression. Blood (2006) 1.90
Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo. Blood (2011) 1.79
Three pathways to mature macrophages in the early mouse yolk sac. Blood (2005) 1.76
Advances in the understanding of haemoglobin switching. Br J Haematol (2010) 1.74
Circulation is established in a stepwise pattern in the mammalian embryo. Blood (2002) 1.73
Stress erythropoiesis: new signals and new stress progenitor cells. Curr Opin Hematol (2011) 1.68
Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus. Blood (2007) 1.68
Molecular changes in the membranes of mouse erythroid cells accompanying differentiation. Cell (1979) 1.66
Embryonic development of the human hematopoietic system. Int J Dev Biol (2005) 1.64
Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse. Genes Dev (2003) 1.62
Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells. Blood (2004) 1.62
Erythropoiesis: model systems, molecular regulators, and developmental programs. IUBMB Life (2009) 1.61
Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development. Arterioscler Thromb Vasc Biol (2005) 1.60
Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny. Dev Dyn (1996) 1.59
Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo. Blood (2006) 1.56
Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis. Proc Natl Acad Sci U S A (2001) 1.56
Novel role for EKLF in megakaryocyte lineage commitment. Blood (2007) 1.53
Transcriptional control of erythropoiesis: emerging mechanisms and principles. Oncogene (2007) 1.52
Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity. Blood (2003) 1.52
Intermolecular interactions of Sprouty proteins and their implications in development and disease. Mol Pharmacol (2009) 1.52
Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice. Nat Genet (1997) 1.51
The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood (2006) 1.48
Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood (2003) 1.45
Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development (1998) 1.45
Blood island formation: longstanding observations and modern interpretations. Exp Hematol (2005) 1.44
Hemoglobin switching during murine embryonic development: evidence for two populations of embryonic erythropoietic progenitor cells. Blood (1986) 1.39
Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development. Mol Cell Biol (2008) 1.36
A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo. Blood (2011) 1.34
Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast. Development (2008) 1.30
Transcription factor networks in erythroid cell and megakaryocyte development. Blood (2011) 1.29
Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region. J Exp Med (2011) 1.25
The fetal liver is a niche for maturation of primitive erythroid cells. Proc Natl Acad Sci U S A (2008) 1.24
Hypoxic stress underlies defects in erythroblast islands in the Rb-null mouse. Blood (2007) 1.15
HoxA3 is an apical regulator of haemogenic endothelium. Nat Cell Biol (2010) 1.13
Engraftment of embryonic hematopoietic cells in conditioned newborn recipients. Blood (1997) 1.11
Runx1 is involved in primitive erythropoiesis in the mouse. Blood (2008) 1.11
From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones. IUBMB Life (2010) 1.11
The first trimester human placenta is a site for terminal maturation of primitive erythroid cells. Blood (2010) 1.09
FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors. EMBO J (2011) 1.08
BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development. Dev Biol (2008) 1.07
Chromatin architecture and transcription factor binding regulate expression of erythrocyte membrane protein genes. Mol Cell Biol (2009) 1.06
Induction of embryonic hematopoietic and endothelial stem/progenitor cells by hedgehog-mediated signals. Differentiation (2001) 1.03
Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf. Blood (2010) 1.03
Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models. Curr Top Dev Biol (2004) 1.02
BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity. Dev Biol (2011) 1.01
Primitive erythropoiesis in the mammalian embryo. Int J Dev Biol (2010) 0.96
Early patterning of the mouse embryo: implications for hematopoietic commitment and differentiation. Exp Hematol (2005) 0.90
Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo. Development (2006) 0.90
Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression. Blood (2006) 1.90
Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo. Blood (2011) 1.79
Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis. Proc Natl Acad Sci U S A (2003) 1.45
Tg(Afp-GFP) expression marks primitive and definitive endoderm lineages during mouse development. Dev Dyn (2006) 1.30
The fetal liver is a niche for maturation of primitive erythroid cells. Proc Natl Acad Sci U S A (2008) 1.24
Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci U S A (2007) 1.19
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing. Mol Cell Biol (2013) 1.18
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J Exp Med (2012) 1.13
Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf. Blood (2010) 1.03
BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity. Dev Biol (2011) 1.01
The specification of early hematopoiesis in the mammal. Curr Opin Hematol (2005) 1.00
Neural crest and the origin of ectomesenchyme: neural fold heterogeneity suggests an alternative hypothesis. Dev Dyn (2004) 1.00
Bone morphogenetic proteins in vertebrate hematopoietic development. J Cell Biochem (2004) 0.96
Hemogenic endothelium: a vessel for blood production. Int J Biochem Cell Biol (2012) 0.95
The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo. Mol Cell Biol (2012) 0.93
The mammalian copper transporters CTR1 and CTR2 and their roles in development and disease. Int J Biochem Cell Biol (2013) 0.87
Use of transgenic fluorescent reporter mouse lines to monitor hematopoietic and erythroid development during embryogenesis. Methods Enzymol (2010) 0.85
Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis. PLoS One (2012) 0.85
Developmental niches for embryonic erythroid cells. Blood Cells Mol Dis (2010) 0.84
Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells (2014) 0.83
Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells. Stem Cells (2009) 0.81
Embryonic regulation of the mouse hematopoietic niche. ScientificWorldJournal (2011) 0.80
Mitochondrially targeted redox probe reveals the variations in oxidative capacity of the haematopoietic cells. Org Biomol Chem (2015) 0.77
Rapid detection of haemotropic mycoplasma infection of feline erythrocytes using a novel flow cytometric approach. Parasit Vectors (2013) 0.77
Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice. Genesis (2013) 0.75
Sex steroid regulation and identification of different transcription units of the SA gene in mouse kidney. J Endocrinol (2004) 0.75