Published in Prostate on December 01, 2006
Role of chemokines in tumor growth. Cancer Lett (2007) 3.36
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis. J Clin Invest (2012) 1.73
CXCL5 promotes prostate cancer progression. Neoplasia (2008) 1.37
Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway. Endocr Relat Cancer (2012) 1.14
Chemokines and chemokine receptors as promoters of prostate cancer growth and progression. Crit Rev Eukaryot Gene Expr (2013) 1.05
CXC receptor-1 silencing inhibits androgen-independent prostate cancer. Cancer Res (2009) 1.00
Mesenchymal stem cells promote mammary cancer cell migration in vitro via the CXCR2 receptor. Cancer Lett (2011) 0.98
Formyl peptide receptor ligands promote wound closure in lung epithelial cells. Am J Respir Cell Mol Biol (2010) 0.90
CXCR2-driven ovarian cancer progression involves upregulation of proinflammatory chemokines by potentiating NF-κB activation via EGFR-transactivated Akt signaling. PLoS One (2013) 0.89
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis. Cancer Res (2011) 0.88
The Ron receptor promotes prostate tumor growth in the TRAMP mouse model. Oncogene (2011) 0.86
NF-κB-Mediated CCL20 Reigns Dominantly in CXCR2-Driven Ovarian Cancer Progression. PLoS One (2016) 0.78
The role of chemoattractant receptors in shaping the tumor microenvironment. Biomed Res Int (2014) 0.77
A New Combinatorial Optimization Approach for Integrated Feature Selection Using Different Datasets: A Prostate Cancer Transcriptomic Study. PLoS One (2015) 0.76
CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help. Nature (2009) 4.03
Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Mol Cell (2005) 2.89
The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc Natl Acad Sci U S A (2002) 2.24
Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med (2005) 2.23
Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med (2002) 2.17
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections. Immunity (2008) 2.13
Regulation of pulmonary fibrosis by chemokine receptor CXCR3. J Clin Invest (2004) 2.10
Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology (2008) 1.98
Chemokine expression during the development and resolution of a pulmonary leukocyte response to influenza A virus infection in mice. J Leukoc Biol (2004) 1.92
An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2. J Biol Chem (2005) 1.89
Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. Int Immunol (2004) 1.85
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol (2009) 1.85
CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. J Immunol (2007) 1.83
Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines. Eur J Immunol (2003) 1.74
The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. J Biol Chem (2009) 1.73
Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. J Neurosci (2004) 1.65
Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival. PLoS One (2007) 1.61
CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. J Immunol (2008) 1.61
Severe disease, unaltered leukocyte migration, and reduced IFN-gamma production in CXCR3-/- mice with experimental autoimmune encephalomyelitis. J Immunol (2006) 1.59
Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma. Crit Care Med (2009) 1.55
Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy. Cancer Res (2005) 1.54
Met-related receptor tyrosine kinase Ron in tumor growth and metastasis. Adv Cancer Res (2008) 1.54
Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member. Cancer Res (2006) 1.52
The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression. Cancer Res (2007) 1.47
Role of CXCR3-induced donor T-cell migration in acute GVHD. Exp Hematol (2003) 1.46
Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation. Cancer Res (2006) 1.43
Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J Immunol (2008) 1.42
Delayed and deficient dermal maturation in mice lacking the CXCR3 ELR-negative CXC chemokine receptor. Am J Pathol (2007) 1.38
Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice. Am J Physiol Gastrointest Liver Physiol (2008) 1.38
C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol (2013) 1.38
Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. J Neurosci (2009) 1.37
Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. Blood (2007) 1.37
Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice. Hepatology (2008) 1.36
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood (2008) 1.33
The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth. FASEB J (2006) 1.33
Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells. J Gastroenterol Hepatol (2012) 1.33
Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers. Cancer Res (2010) 1.31
Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion. Am J Pathol (2002) 1.31
Ron receptor signaling augments mammary tumor formation and metastasis in a murine model of breast cancer. Cancer Res (2005) 1.29
Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia. Am J Physiol Gastrointest Liver Physiol (2006) 1.28
CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am J Respir Crit Care Med (2012) 1.28
Divergent functions of CD4+ T lymphocytes in acute liver inflammation and injury after ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol (2005) 1.27
Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice. J Immunol (2010) 1.24
Lymphocyte function during hepatic ischemia/reperfusion injury. J Leukoc Biol (2007) 1.24
Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol (2009) 1.24
Blockade of CXCR3 receptor:ligand interactions reduces leukocyte recruitment to the lung and the severity of experimental idiopathic pneumonia syndrome. J Immunol (2004) 1.24
Ischemic and non-ischemic acute kidney injury cause hepatic damage. Kidney Int (2009) 1.23
Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody. Transplantation (2008) 1.22
Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor. Exp Cell Res (2003) 1.21
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice. Hepatology (2012) 1.21
Substance P signaling mediates BMP-dependent heterotopic ossification. J Cell Biochem (2011) 1.21
CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection. Eur J Immunol (2005) 1.20
IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. J Immunol (2006) 1.19
Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia. J Clin Invest (2005) 1.19
The cannabinoid receptor 2 is critical for the host response to sepsis. J Immunol (2009) 1.18
Ischemia/reperfusion injury. J Surg Res (2002) 1.16
CXC chemokines play a critical role in liver injury, recovery, and regeneration. Am J Surg (2009) 1.16
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response. PLoS One (2009) 1.16
CD4-expressing cells are early mediators of the innate immune system during sepsis. Shock (2008) 1.15
Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines. Neoplasia (2010) 1.15
Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia. J Immunol (2002) 1.15
Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. Neurosci Res (2002) 1.14
The roles of streptozotocin neurotoxicity and neutral endopeptidase in murine experimental diabetic neuropathy. Exp Diabetes Res (2010) 1.13
3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation. Mol Cell Biol (2006) 1.13
Efficient T-cell surveillance of the CNS requires expression of the CXC chemokine receptor 3. J Neurosci (2004) 1.13
Chemokine receptor deficiency is associated with increased chemokine expression in the peripheral and central nervous systems and increased resistance to herpetic encephalitis. J Neuroimmunol (2005) 1.12
Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation. J Am Coll Surg (2012) 1.10
Attenuation of acute lung inflammation induced by cigarette smoke in CXCR3 knockout mice. Respir Res (2008) 1.10
Ron receptor tyrosine kinase negatively regulates TNFalpha production in alveolar macrophages by inhibiting NF-kappaB activity and Adam17 production. Shock (2010) 1.09
Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. Hepatology (2008) 1.09
CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease. J Am Soc Nephrol (2008) 1.08
MCP-1 expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci (2002) 1.08
Endogenous regulation of the acute inflammatory response. Mol Cell Biochem (2002) 1.08
CXC chemokine signaling in the liver: impact on repair and regeneration. Hepatology (2011) 1.07
HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding. Diabetes (2013) 1.07
Distinct contributions of CD4+ T cell subsets in hepatic ischemia/reperfusion injury. Am J Physiol Gastrointest Liver Physiol (2009) 1.07
Gammadelta T cells mitigate the organ injury and mortality of sepsis. J Leukoc Biol (2007) 1.07
Activation of hepatocytes by extracellular heat shock protein 72. Am J Physiol Cell Physiol (2008) 1.07
CXCR3 ligands contribute to Th1-induced inflammation but not to homing of Th1 cells into the lung. Exp Lung Res (2008) 1.06
Age-dependent responses to hepatic ischemia/reperfusion injury. Shock (2005) 1.06
Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice. J Immunol (2005) 1.06
CCR5 chemokine receptor mediates recruitment of MHC class II-positive Langerhans cells in the mouse corneal epithelium. Invest Ophthalmol Vis Sci (2005) 1.06
Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure. Hepatology (2002) 1.05
Substance P modulates colitis-associated fibrosis. Am J Pathol (2010) 1.05
C3a and C5a promote renal ischemia-reperfusion injury. J Am Soc Nephrol (2012) 1.05
Impaired lung dendritic cell activation in CCR2 knockout mice. Am J Pathol (2004) 1.04
Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion. J Invest Surg (2003) 1.04
An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation. J Immunol (2008) 1.04