Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.

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Published in PLoS One on September 05, 2007

Authors

Manfred Thiel1, Charles C Caldwell, Simone Kreth, Satoshi Kuboki, P Chen, Patrick Smith, Akio Ohta, Alex B Lentsch, Dmitry Lukashev, Michail V Sitkovsky

Author Affiliations

1: Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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