Published in FASEB J on October 11, 2011
Physiological and molecular determinants of embryo implantation. Mol Aspects Med (2013) 1.33
Advances in the pathophysiology of pre-eclampsia and related podocyte injury. Kidney Int (2014) 1.03
Notch1 is regulated by chorionic gonadotropin and progesterone in endometrial stromal cells and modulates decidualization in primates. Endocrinology (2012) 0.94
Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization. J Clin Endocrinol Metab (2014) 0.91
Notch signaling pathway and human placenta. Int J Med Sci (2012) 0.88
Leukocyte driven-decidual angiogenesis in early pregnancy. Cell Mol Immunol (2014) 0.88
Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer. Cancer Res (2013) 0.86
17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells. PLoS One (2013) 0.83
Delta-like ligand (DLL)1 expression in early mouse decidua and its localization to uterine natural killer cells. PLoS One (2012) 0.83
Notch2 controls prolactin and insulin-like growth factor binding protein-1 expression in decidualizing human stromal cells of early pregnancy. PLoS One (2014) 0.81
Notch Signaling in Inflammation-Induced Preterm Labor. Sci Rep (2015) 0.78
Aberrant expression of Notch1/numb/snail signaling, an epithelial mesenchymal transition related pathway, in adenomyosis. Reprod Biol Endocrinol (2015) 0.77
The Krüppel-like factors in female reproductive system pathologies. J Mol Endocrinol (2015) 0.77
Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility. Proc Natl Acad Sci U S A (2016) 0.76
Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus. Vasc Cell (2015) 0.75
Intrauterine human chorionic gonadotropin infusion in oocyte donors promotes endometrial synchrony and induction of early decidual markers for stromal survival: a randomized clinical trial. Hum Reprod (2016) 0.75
Localisation of the Notch family in the human endometrium of fertile and infertile women. J Mol Histol (2014) 0.75
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A (2001) 68.44
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59
Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res (2003) 52.74
Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83
The canonical Notch signaling pathway: unfolding the activation mechanism. Cell (2009) 14.72
Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol (2006) 13.12
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature (1998) 10.58
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature (1999) 10.36
Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity (1999) 8.33
Notch signaling. Science (1995) 7.22
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol Cell (2000) 5.53
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29
The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. Development (1994) 3.99
The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc Natl Acad Sci U S A (1998) 3.99
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev (2004) 3.95
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell (1997) 3.47
Rational targeting of Notch signaling in cancer. Oncogene (2008) 3.02
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature (2000) 2.85
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol (2005) 2.81
Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis (2005) 2.67
The ins and outs of notch signaling. Mol Cell Neurosci (1997) 2.61
Targeting Notch to target cancer stem cells. Clin Cancer Res (2010) 2.46
Essential role of endothelial Notch1 in angiogenesis. Circulation (2005) 2.28
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res (2008) 2.19
p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev (2005) 2.17
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet (2006) 2.11
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res (2004) 2.10
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
Turning it up a Notch: cross-talk between TGF beta and Notch signaling. Bioessays (2005) 1.95
A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis. Proc Natl Acad Sci U S A (2003) 1.92
Bone morphogenetic protein 2 functions via a conserved signaling pathway involving Wnt4 to regulate uterine decidualization in the mouse and the human. J Biol Chem (2007) 1.91
Smooth Muscle alpha-actin is a direct target of Notch/CSL. Circ Res (2006) 1.90
Emerging role of Notch in stem cells and cancer. Cancer Lett (2008) 1.88
Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood (2008) 1.69
Progesterone inhibits estrogen-induced cyclin D1 and cdk4 nuclear translocation, cyclin E- and cyclin A-cdk2 kinase activation, and cell proliferation in uterine epithelial cells in mice. Mol Cell Biol (1999) 1.69
Endocrine control of the timing of endometrial sensitivity to a decidual stimulus. Biol Reprod (1972) 1.67
Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt. Virology (2001) 1.63
Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor. Endocrinology (2005) 1.59
Uterine Wnt/beta-catenin signaling is required for implantation. Proc Natl Acad Sci U S A (2005) 1.57
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members. Proc Natl Acad Sci U S A (2001) 1.54
Control of E2F activity by p21Waf1/Cip1. Oncogene (1999) 1.41
Death or survival--progesterone-dependent cell fate decisions in the human endometrial stroma. J Mol Endocrinol (2006) 1.41
FOXO1A differentially regulates genes of decidualization. Endocrinology (2006) 1.39
In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol (2008) 1.34
The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila. Trends Genet (1988) 1.29
Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene (2009) 1.29
Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A (2009) 1.28
Cyclin D3 in the mouse uterus is associated with the decidualization process during early pregnancy. J Mol Endocrinol (1999) 1.16
Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis. Oncogene (1999) 1.15
Inactivation of nuclear Wnt-beta-catenin signaling limits blastocyst competency for implantation. Development (2008) 1.14
Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways. J Cell Physiol (2004) 1.13
Regulating the Notch pathway in embryonic, adult and old stem cells. Curr Opin Pharmacol (2007) 1.10
Modulation of the baboon (Papio anubis) uterine endometrium by chorionic gonadotrophin during the period of uterine receptivity. Proc Natl Acad Sci U S A (1999) 1.10
Mechanisms of trophoblast invasiveness and their control: the role of proteases and protease inhibitors. Cancer Metastasis Rev (1990) 1.07
The biology of decidual cells. Adv Reprod Physiol (1971) 1.03
Expression and distribution of notch protein members in human placenta throughout pregnancy. Placenta (2006) 1.01
Epithelial-stromal interaction and progesterone receptors in the mouse uterus. Semin Reprod Med (2010) 1.01
The interaction of the Wnt and Notch pathways modulates natural killer versus T cell differentiation. Stem Cells (2007) 0.99
Effect of decidualization on the expression of bax and bcl-2 in the rat uterine endometrium. Endocrinology (1996) 0.96
Apoptosis and apoptosis-related proteins in human endometrium. Mol Cell Endocrinol (2000) 0.95
Potential roles of decidual prolactin in early pregnancy. Reproduction (2001) 0.94
Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer. Adv Enzyme Regul (2009) 0.94
Molecular mechanisms involved in progesterone receptor regulation of uterine function. J Steroid Biochem Mol Biol (2006) 0.92
Involvement of cyclin-dependent kinase inhibitor p27Kip1 in growth inhibition of endometrium in the secretory phase and of hyperplastic endometrium treated with progesterone. Mol Hum Reprod (1998) 0.91
Human chorionic gonadotropin and decidualization in vitro inhibits cytochalasin-D-induced apoptosis in cultured endometrial stromal fibroblasts. Endocrinology (2006) 0.89
Modulation of the action of chorionic gonadotropin in the baboon (Papio anubis) uterus by a progesterone receptor antagonist (ZK 137. 316). Biol Reprod (2000) 0.88
Notch and NOXA-related pathways in melanoma cells. J Investig Dermatol Symp Proc (2005) 0.87
Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. J Steroid Biochem Mol Biol (2006) 0.85
Regulation of insulin-like growth factor-binding proteins in the baboon (Papio anubis) uterus during early pregnancy. Endocrinology (1992) 0.84
Relationship between luteinizing hormone and decidual luteotropin in the maintenance of luteal steroidogenesis. Biol Reprod (1984) 0.80
Myosin heavy chain degradation during apoptosis in endothelial cells. Cell Prolif (2000) 0.78
[The expression of chemokine receptors in CD56(bright) CD16- natural killer cells and the mechanism of their recruitment in decidua]. Zhonghua Yi Xue Za Zhi (2004) 0.76
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature (2005) 11.49
Notch1 functions as a tumor suppressor in mouse skin. Nat Genet (2003) 6.76
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med (2002) 4.04
Transcription factor RORα is critical for nuocyte development. Nat Immunol (2012) 3.72
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity (2007) 3.19
Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med (2004) 3.16
Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell (2008) 3.08
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep (2008) 3.03
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells. Gastroenterology (2011) 2.94
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity (2002) 2.83
Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study. Am J Obstet Gynecol (2008) 2.82
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol (2005) 2.81
Targeting Notch to target cancer stem cells. Clin Cancer Res (2010) 2.46
Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood (2004) 2.44
Contribution of Notch signaling activation to human glioblastoma multiforme. J Neurosurg (2007) 2.43
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. Nat Med (2006) 2.35
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31
Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. Immunity (2010) 2.29
Essential role of endothelial Notch1 in angiogenesis. Circulation (2005) 2.28
Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Res (2005) 2.27
Notch signaling is required for exocrine regeneration after acute pancreatitis. Gastroenterology (2007) 2.26
Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett (2011) 2.24
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology (2008) 2.21
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res (2008) 2.19
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J Exp Med (2008) 2.17
Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene (2003) 2.16
Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation. J Exp Med (2005) 2.15
Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Lett (2006) 2.14
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature (2012) 2.13
Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol (2007) 2.09
Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis. Blood (2007) 2.06
Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity (2008) 2.05
Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. J Cell Biochem (2011) 1.94
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. PLoS One (2010) 1.92
Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res (2006) 1.91
Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria. Dev Cell (2010) 1.90
Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab (2011) 1.89
Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Res (2007) 1.88
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A (2010) 1.84
Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell (2009) 1.84
Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke. Nat Med (2006) 1.82
WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J (2010) 1.79
Notch inhibits osteoblast differentiation and causes osteopenia. Endocrinology (2008) 1.78
Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development (2010) 1.78
Involvement of Notch signaling in hippocampal synaptic plasticity. Proc Natl Acad Sci U S A (2004) 1.77
Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling. Circ Res (2006) 1.75
Investigating socio-economic disparities in preterm birth: evidence for selective study participation and selection bias. Paediatr Perinat Epidemiol (2009) 1.75
TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J Immunol (2003) 1.75
Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. Hepatology (2005) 1.73
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med (2007) 1.73
Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells. J Neurosci (2010) 1.72
Stress pathways to spontaneous preterm birth: the role of stressors, psychological distress, and stress hormones. Am J Epidemiol (2009) 1.72
Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood (2008) 1.69
Notch1 is required for neuronal and glial differentiation in the cerebellum. Development (2002) 1.69
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68
Notch-induced T cell development requires phosphoinositide-dependent kinase 1. EMBO J (2007) 1.67
Notch signaling in solid tumors. Curr Top Dev Biol (2010) 1.66
Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol (2002) 1.65
Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene (2005) 1.63
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood (2010) 1.60
Smooth muscle Notch1 mediates neointimal formation after vascular injury. Circulation (2009) 1.58
Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell (2008) 1.58
Loss of cutaneous TSLP-dependent immune responses skews the balance of inflammation from tumor protective to tumor promoting. Cancer Cell (2012) 1.56
Notch inhibitors for cancer treatment. Pharmacol Ther (2013) 1.55
Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation. Dev Biol (2005) 1.54
Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Dev Cell (2007) 1.49
Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. J Neurosci (2004) 1.48
Stem cells living with a Notch. Development (2013) 1.48
Notch1 is essential for postnatal hair follicle development and homeostasis. Dev Biol (2005) 1.48
DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. J Clin Invest (2015) 1.45
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol Cancer Ther (2004) 1.40
Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn (2007) 1.40
Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines. Blood (2004) 1.38
Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. Anticancer Res (2010) 1.37
Notch signaling in lymphopoiesis. Semin Immunol (2003) 1.37
Transendothelial function of human metastatic melanoma cells: role of the microenvironment in cell-fate determination. Cancer Res (2002) 1.36
Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A (2002) 1.35
Involvement of notch signaling in wound healing. PLoS One (2007) 1.35
Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity (2010) 1.35
Notch in T-ALL: new players in a complex disease. Trends Immunol (2011) 1.35
In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol (2008) 1.34
Mechanisms of T cell development and transformation. Annu Rev Cell Dev Biol (2011) 1.33
The notch regulator MAML1 interacts with p53 and functions as a coactivator. J Biol Chem (2007) 1.33
IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J (2011) 1.33
γ-Secretase inhibitors and modulators. Biochim Biophys Acta (2013) 1.32
The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development. J Exp Med (2008) 1.31
Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J Immunol (2004) 1.31
The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells. J Immunol (2002) 1.30
Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway. Cancer Res (2008) 1.30
Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells. J Clin Invest (2011) 1.29
Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells. Cancer Lett (2013) 1.28
Notch signaling is necessary but not sufficient for differentiation of dendritic cells. Blood (2003) 1.27
Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity. Dev Cell (2011) 1.26
Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene (2003) 1.25
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity (2012) 1.24
Control of the adaptive response of the heart to stress via the Notch1 receptor pathway. J Exp Med (2008) 1.24
Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells. Lab Invest (2006) 1.24
Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition. Onco Targets Ther (2013) 1.23