Barry Shane

Author PubWeight™ 37.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. J Biol Chem 2002 2.20
2 A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J Nutr 2006 1.82
3 Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor. Am J Physiol Endocrinol Metab 2003 1.44
4 Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr 2011 1.43
5 Biomarkers of folate status in NHANES: a roundtable summary. Am J Clin Nutr 2011 1.43
6 Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood 2002 1.34
7 Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr 2005 1.17
8 Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides. J Nutr 2005 1.17
9 Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis. J Biol Chem 2012 1.16
10 Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem 2008 1.14
11 Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes. PLoS One 2011 1.14
12 Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase. J Biol Chem 2006 1.13
13 In silico experimentation with a model of hepatic mitochondrial folate metabolism. Theor Biol Med Model 2006 1.10
14 Mathematical modeling of folate metabolism: predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis. Cancer Epidemiol Biomarkers Prev 2008 1.08
15 Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects. BMC Med Genet 2012 1.08
16 Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model. Carcinogenesis 2005 1.07
17 Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L. Am J Hum Genet 2002 1.02
18 Cerebral vascular dysfunction in methionine synthase-deficient mice. Circulation 2005 1.01
19 Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women. J Nutr 2005 0.98
20 Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population. Am J Med Genet A 2010 0.96
21 Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficiency or excess. Part I--Folate, Vitamin B12, Vitamin B6. J Matern Fetal Neonatal Med 2010 0.95
22 Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status? Am J Clin Nutr 2011 0.94
23 Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association. Mol Genet Metab 2005 0.93
24 Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficiency or excess. Part II--vitamin D, vitamin A, iron, zinc, iodine, essential fatty acids. J Matern Fetal Neonatal Med 2010 0.91
25 Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin Pharmacokinet 2010 0.90
26 Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers. Cancer Epidemiol Biomarkers Prev 2011 0.86
27 Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. J Nutr Biochem 2006 0.84
28 Folate fortification: enough already? Am J Clin Nutr 2003 0.81
29 Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation. J Nutr 2003 0.81
30 Is low iron status a risk factor for neural tube defects? Birth Defects Res A Clin Mol Teratol 2014 0.76
31 Folate-responsive birth defects: of mice and women. Am J Clin Nutr 2011 0.75
32 Glutamate carboxypeptidase II and folate deficiencies result in reciprocal protection against cognitive and social deficits in mice: implications for neurodevelopmental disorders. Dev Neurobiol 2012 0.75