Published in J Gen Physiol on September 11, 2006
Peripheral chemoreceptors: function and plasticity of the carotid body. Compr Physiol (2012) 2.30
Interactions of multiple gas-transducing systems: hallmarks and uncertainties of CO, NO, and H2S gas biology. Antioxid Redox Signal (2010) 1.63
Protein kinase G-regulated production of H2S governs oxygen sensing. Sci Signal (2015) 1.61
Control of intracellular heme levels: heme transporters and heme oxygenases. Biochim Biophys Acta (2011) 1.48
Modulation of BKCa channel gating by endogenous signaling molecules. Physiology (Bethesda) (2009) 1.38
Sensing hypoxia: physiology, genetics and epigenetics. J Physiol (2013) 1.36
Carbon monoxide as an endogenous vascular modulator. Am J Physiol Heart Circ Physiol (2011) 1.23
The RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels. Proc Natl Acad Sci U S A (2008) 1.09
Developmental change of T-type Ca2+ channel expression and its role in rat chromaffin cell responsiveness to acute hypoxia. J Physiol (2009) 1.06
Carotid body chemosensory responses in mice deficient of TASK channels. J Gen Physiol (2010) 1.04
Hydrogen sulfide as an oxygen sensor. Antioxid Redox Signal (2014) 0.99
Hypoxic pulmonary vasoconstriction: mechanisms of oxygen-sensing. Curr Opin Anaesthesiol (2011) 0.96
Behavioral responses to hypoxia in Drosophila larvae are mediated by atypical soluble guanylyl cyclases. Genetics (2010) 0.96
Cellular properties and chemosensory responses of the human carotid body. J Physiol (2013) 0.94
Oxygen Sensing and Homeostasis. Physiology (Bethesda) (2015) 0.93
Heme oxygenase is necessary for the excitatory response of cultured neonatal rat rostral ventrolateral medulla neurons to hypoxia. Am J Physiol Regul Integr Comp Physiol (2008) 0.91
Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body. Respir Physiol Neurobiol (2012) 0.91
Gasotransmitter regulation of ion channels: a key step in O2 sensing by the carotid body. Physiology (Bethesda) (2014) 0.86
Mitochondrial complex III: an essential component of universal oxygen sensing machinery? Respir Physiol Neurobiol (2010) 0.83
Adenosine A₂a receptors and O₂ sensing in development. Am J Physiol Regul Integr Comp Physiol (2011) 0.81
K(+) channels in O(2) sensing and postnatal development of carotid body glomus cell response to hypoxia. Respir Physiol Neurobiol (2012) 0.81
The neurogenic niche in the carotid body and its applicability to antiparkinsonian cell therapy. J Neural Transm (Vienna) (2009) 0.78
Hypoxia reduces KCa channel activity by inducing Ca2+ spark uncoupling in cerebral artery smooth muscle cells. Am J Physiol Cell Physiol (2007) 0.78
Carotid chemoreceptor development in mice. Respir Physiol Neurobiol (2012) 0.76
Carotid body oxygen sensing and adaptation to hypoxia. Pflugers Arch (2015) 0.76
Interaction of Hydrogen Sulfide with Oxygen Sensing under Hypoxia. Oxid Med Cell Longev (2015) 0.76
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science (2000) 8.64
The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol (1997) 7.50
Acute oxygen-sensing mechanisms. N Engl J Med (2005) 4.80
Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science (2004) 3.28
Chemotransduction in the carotid body: K+ current modulated by PO2 in type I chemoreceptor cells. Science (1988) 3.24
Cellular mechanism of oxygen sensing. Annu Rev Physiol (2001) 2.84
Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury. Proc Natl Acad Sci U S A (1999) 2.84
Cloning and expression of cDNA for rat heme oxygenase. Proc Natl Acad Sci U S A (1985) 2.18
Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res (2000) 2.09
Oxygen sensing by the carotid body chemoreceptors. J Appl Physiol (1985) (2000) 1.85
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels. Nature (2003) 1.84
Low glucose-sensing cells in the carotid body. Nat Neurosci (2002) 1.76
O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. Proc Natl Acad Sci U S A (1999) 1.67
Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice. Neuron (1995) 1.63
Ca(2+)-activated K+ channels in isolated type I cells of the neonatal rat carotid body. J Physiol (1995) 1.54
Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells. J Physiol (1997) 1.44
The chemical modification of KCa channels by carbon monoxide in vascular smooth muscle cells. J Biol Chem (1997) 1.42
The mitochondrial SDHD gene is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to hypoxia. Mol Cell Biol (2004) 1.37
O2-sensitive K+ currents in carotid body chemoreceptor cells from normoxic and chronically hypoxic rats and their roles in hypoxic chemotransduction. Proc Natl Acad Sci U S A (1995) 1.34
Adrenomedullary function in the neonatal rat: responses to acute hypoxia. J Physiol (1985) 1.32
NADPH oxidase is an O2 sensor in airway chemoreceptors: evidence from K+ current modulation in wild-type and oxidase-deficient mice. Proc Natl Acad Sci U S A (2000) 1.26
Secretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammonium. Proc Natl Acad Sci U S A (2000) 1.19
Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia. Neuroscience (2000) 1.19
Decreased activity of the antioxidant heme oxygenase enzyme: implications in ischemia and in Alzheimer's disease. Free Radic Biol Med (2002) 1.04
Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing. J Physiol (2004) 0.98
Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2. Biochem Biophys Res Commun (2004) 0.95
Decreased expression of maxi-K+ channel beta1-subunit and altered vasoregulation in hypoxia. Circulation (2005) 0.89
Role of H2O2 and heme-containing O2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression. Am J Physiol (1998) 0.89
Cell biology. Oxygen sensing: it's a gas! Science (2004) 0.88
Oxygen-sensing by ion channels and mitochondrial function in carotid body glomus cells. Novartis Found Symp (2006) 0.79
Multiple facets of maxi-k+ channels: the heme connection. J Gen Physiol (2005) 0.78
Acute oxygen-sensing mechanisms. N Engl J Med (2005) 4.80
Absolute requirement of GDNF for adult catecholaminergic neuron survival. Nat Neurosci (2008) 2.93
Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body. Cell (2007) 2.63
Exclusive consolidated memory phases in Drosophila. Science (2004) 2.50
Low glucose-sensing cells in the carotid body. Nat Neurosci (2002) 1.76
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Mol Med (2012) 1.75
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice. Mol Cell Biol (2008) 1.62
Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction. Circ Res (2011) 1.60
Autotransplantation of human carotid body cell aggregates for treatment of Parkinson's disease. Neurosurgery (2003) 1.47
The mitochondrial SDHD gene is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to hypoxia. Mol Cell Biol (2004) 1.37
Induction of T-type calcium channel gene expression by chronic hypoxia. J Biol Chem (2003) 1.27
Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression. J Biol Chem (2007) 1.21
Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells. J Physiol (2003) 1.21
Mechanisms of low-glucose sensitivity in carotid body glomus cells. Diabetes (2007) 1.18
Developmental change of T-type Ca2+ channel expression and its role in rat chromaffin cell responsiveness to acute hypoxia. J Physiol (2009) 1.06
Carotid body chemosensory responses in mice deficient of TASK channels. J Gen Physiol (2010) 1.04
GDNF is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after injury of the nigrostriatal pathway. J Neurosci (2012) 1.01
Induction of the glucose-6-phosphate dehydrogenase gene expression by chronic hypoxia in PC12 cells. FEBS Lett (2004) 0.99
Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation. J Neurosci (2005) 0.99
Oxygen tension regulates mitochondrial DNA-encoded complex I gene expression. J Biol Chem (2005) 0.98
Ca2+ channel-sarcoplasmic reticulum coupling: a mechanism of arterial myocyte contraction without Ca2+ influx. EMBO J (2003) 0.96
Rat adrenal chromaffin cells are neonatal CO2 sensors. J Neurosci (2005) 0.95
Developmental changes of chromaffin cell secretory response to hypoxia studied in thin adrenal slices. Pflugers Arch (2006) 0.95
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2. J Physiol (2013) 0.94
Cellular properties and chemosensory responses of the human carotid body. J Physiol (2013) 0.94
Metabotropic Ca2+ channel-induced calcium release in vascular smooth muscle. Cell Calcium (2007) 0.94
Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α. PLoS One (2011) 0.92
Mechanisms of acute oxygen sensing by the carotid body: lessons from genetically modified animals. Respir Physiol Neurobiol (2007) 0.91
Decreased expression of maxi-K+ channel beta1-subunit and altered vasoregulation in hypoxia. Circulation (2005) 0.89
Higher seroprevalence of Trypanosoma cruzi infection in dogs than in humans in an urban area of Campeche, Mexico. Vector Borne Zoonotic Dis (2010) 0.89
Oxygen sensing in the carotid body. Ann N Y Acad Sci (2009) 0.89
Differential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunction. Mol Cell Biol (2012) 0.88
GDNF and protection of adult central catecholaminergic neurons. J Mol Endocrinol (2011) 0.87
Neuroprotection by transgenic expression of glucose-6-phosphate dehydrogenase in dopaminergic nigrostriatal neurons of mice. J Neurosci (2006) 0.87
Quantifiable diagnosis of muscular dystrophies and neurogenic atrophies through network analysis. BMC Med (2013) 0.86
Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia. J Biol Chem (2012) 0.86
GDNF is required for neural colonization of the pancreas. Development (2013) 0.85
Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries. Cardiovasc Res (2012) 0.85
Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats. J Neurosci (2003) 0.83
Direct confocal acquisition of fluorescence from X-gal staining on thick tissue sections. Sci Rep (2013) 0.83
Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study. J Neurol Neurosurg Psychiatry (2007) 0.82
Topological progression in proliferating epithelia is driven by a unique variation in polygon distribution. PLoS One (2013) 0.82
Carotid body thin slices: responses of glomus cells to hypoxia and K(+)-channel blockers. Respir Physiol Neurobiol (2002) 0.82
Differential functional properties of Ca2+ stores in pulmonary arterial conduit and resistance myocytes. Cell Calcium (2004) 0.82
Intermediate alleles at the FRAXA and FRAXE loci in Parkinson's disease. Parkinsonism Relat Disord (2011) 0.82
Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels. Trends Cardiovasc Med (2012) 0.81
Neuroprotective and reparative effects of carotid body grafts in a chronic MPTP model of Parkinson's disease. Neurobiol Aging (2012) 0.81
Hypoxia inducible factor-2alpha stabilization and maxi-K+ channel beta1-subunit gene repression by hypoxia in cardiac myocytes: role in preconditioning. Circ Res (2009) 0.81
Hypoxia inhibits vasoconstriction induced by metabotropic Ca2+ channel-induced Ca2+ release in mammalian coronary arteries. Cardiovasc Res (2009) 0.80
Age-mediated transcriptomic changes in adult mouse substantia nigra. PLoS One (2013) 0.80
CDase is a pan-ceramidase in Drosophila. Mol Biol Cell (2010) 0.80
Dopaminergic cells of the carotid body: physiological significance and possible therapeutic applications in Parkinson's disease. Brain Res Bull (2002) 0.79
T-type Ca2+ channels in mouse embryonic stem cells: modulation during cell cycle and contribution to self-renewal. Am J Physiol Cell Physiol (2011) 0.79
Tonic arterial contraction mediated by L-type Ca2+ channels requires sustained Ca2+ influx, G protein-associated Ca2+ release, and RhoA/ROCK activation. Eur J Pharmacol (2012) 0.79
Short communication: genetic ablation of L-type Ca2+ channels abolishes depolarization-induced Ca2+ release in arterial smooth muscle. Circ Res (2010) 0.79
Neural stem cells and transplantation studies in Parkinson's disease. Adv Exp Med Biol (2012) 0.79
α-Haemoglobin regulates sympathoadrenal cell metabolism to maintain a catecholaminergic phenotype. Biochem J (2012) 0.78
AQP1 mediates water transport in the carotid body. Pflugers Arch (2010) 0.77
Metabotropic Ca(2+) channel-induced Ca(2+) release and ATP-dependent facilitation of arterial myocyte contraction. Proc Natl Acad Sci U S A (2006) 0.77
Studies on glomus cell sensitivity to hypoxia in carotid body slices. Adv Exp Med Biol (2003) 0.77
Glucose sensing cells in the carotid body. Adv Exp Med Biol (2003) 0.77
Mesencephalic and striatal protein profiles in mice over-expressing glucose-6-phosphate dehydrogenase in dopaminergic neurons. J Proteomics (2010) 0.76
Glucose-6-phosphate dehydrogenase activity in Parkinson's disease. J Neurol (2008) 0.76
Tissue Dynamics of the Carotid Body Under Chronic Hypoxia: A Computational Study. Adv Exp Med Biol (2015) 0.75
Neurotrophic Properties, Chemosensory Responses and Neurogenic Niche of the Human Carotid Body. Adv Exp Med Biol (2015) 0.75
Maxi-K+ channel beta1 expression in sleep apnea patients and its modulation by CPAP treatment. Am J Hypertens (2008) 0.75
Mitochondrial complex II participates in normoxic and hypoxic regulation of α-keto acids in the murine heart. J Mol Cell Cardiol (2010) 0.75
A new metabotropic role for L-type Ca(2+) channels in vascular smooth muscle contraction. Curr Vasc Pharmacol (2013) 0.75