Published in Am J Physiol Regul Integr Comp Physiol on September 14, 2006
Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal. Circ Res (2008) 1.42
Anemia and red blood cell transfusion in neurocritical care. Crit Care (2009) 1.23
Hypoxia inducible factor-1: its potential role in cerebral ischemia. Cell Mol Neurobiol (2012) 1.05
Low nitric oxide synthases (NOSs) in eyes with age-related macular degeneration (AMD). Exp Eye Res (2009) 1.03
CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin. Am J Pathol (2011) 0.97
HIF-1 and ventilatory acclimatization to chronic hypoxia. Respir Physiol Neurobiol (2008) 0.94
Intermittent pneumatic leg compressions acutely upregulate VEGF and MCP-1 expression in skeletal muscle. Am J Physiol Heart Circ Physiol (2010) 0.91
Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia. Proc Natl Acad Sci U S A (2011) 0.85
Sumoylation of hypoxia-inducible factor-1α ameliorates failure of brain stem cardiovascular regulation in experimental brain death. PLoS One (2011) 0.84
Heme oxygenase-1 plays a pro-life role in experimental brain stem death via nitric oxide synthase I/protein kinase G signaling at rostral ventrolateral medulla. J Biomed Sci (2010) 0.83
Is methemoglobin an inert bystander, biomarker or a mediator of oxidative stress--The example of anemia? Redox Biol (2013) 0.82
Expression of pigment epithelium-derived factor and thrombospondin-1 regulate proliferation and migration of retinal pigment epithelial cells. Physiol Rep (2015) 0.81
Acute anemia elicits cognitive dysfunction and evidence of cerebral cellular hypoxia in older rats with systemic hypertension. Anesthesiology (2010) 0.80
HIF-1α SUMOylation affects the stability and transcriptional activity of HIF-1α in human lens epithelial cells. Graefes Arch Clin Exp Ophthalmol (2015) 0.77
Metoprolol impairs resistance artery function in mice. J Appl Physiol (1985) (2011) 0.76
Impact of Hemoglobin Levels and Anemia on Mortality in Acute Stroke: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis. J Am Heart Assoc (2016) 0.75
Anemia management after acute brain injury. Crit Care (2016) 0.75
Evaluation of neuronal apoptosis precursors in an experimental model of acute normovolemic hemodilution. PLoS One (2014) 0.75
Perioperative stroke. Can J Anaesth (2015) 0.75
Experimental assessment of oxygen homeostasis during acute hemodilution: the integrated role of hemoglobin concentration and blood pressure. Intensive Care Med Exp (2017) 0.75
Functional and anatomical evidence of cerebral tissue hypoxia in young sickle cell anemia mice. J Cereb Blood Flow Metab (2016) 0.75
One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med (2003) 11.77
Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med (2011) 9.96
Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. Ann Thorac Surg (2007) 5.32
A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA (2004) 5.20
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med (2008) 5.20
2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines. Ann Thorac Surg (2011) 4.84
Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med (2010) 3.83
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med (2007) 3.64
Acute kidney injury after cardiac surgery: focus on modifiable risk factors. Circulation (2009) 3.10
A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation (2002) 2.76
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One (2012) 2.75
Selective β1-antagonism with bisoprolol is associated with fewer postoperative strokes than atenolol or metoprolol: a single-center cohort study of 44,092 consecutive patients. Anesthesiology (2013) 2.69
Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat Med (2006) 2.65
Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation. Circulation (2007) 2.60
Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive. Nat Med (2003) 2.40
Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med (2006) 2.39
Improving the diagnosis of acute heart failure using a validated prediction model. J Am Coll Cardiol (2009) 2.18
Therapeutic arteriogenesis by ultrasound-mediated VEGF165 plasmid gene delivery to chronically ischemic skeletal muscle. Circ Res (2007) 2.14
Treatment with a highly selective β₁ antagonist causes dose-dependent impairment of cerebral perfusion after hemodilution in rats. Anesth Analg (2013) 2.04
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail. Mol Cell Biol (2006) 2.03
The future of decision-making in critical care after Cuthbertson v. Rasouli. Can J Anaesth (2014) 2.02
Regulation of endocytosis via the oxygen-sensing pathway. Nat Med (2009) 2.00
Protective role of angiopoietin-1 in experimental pulmonary hypertension. Circ Res (2003) 1.98
C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation (2004) 1.94
Endothelial progenitor cells: new hope for a broken heart. Circulation (2003) 1.93
Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury. Neurocrit Care (2006) 1.87
Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia? Circ Res (2004) 1.83
Simulation-based training improves physicians' performance in patient care in high-stakes clinical setting of cardiac surgery. Anesthesiology (2010) 1.83
Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions. Proc Natl Acad Sci U S A (2007) 1.82
Breastfeeding of newborns by mothers carrying hepatitis B virus: a meta-analysis and systematic review. Arch Pediatr Adolesc Med (2011) 1.76
Organ donor management in Canada: recommendations of the forum on Medical Management to Optimize Donor Organ Potential. CMAJ (2006) 1.73
Overexpression of endothelial NO synthase induces angiogenesis in a co-culture model. Cardiovasc Res (2002) 1.71
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. J Clin Invest (2002) 1.70
National recommendations for donation after cardiocirculatory death in Canada: Donation after cardiocirculatory death in Canada. CMAJ (2006) 1.68
Meta-analysis of the effects of endothelin receptor blockade on survival in experimental heart failure. J Card Fail (2003) 1.64
Transfusion triggers for guiding RBC transfusion for cardiovascular surgery: a systematic review and meta-analysis*. Crit Care Med (2014) 1.61
Traumatic brain injury: can the consequences be stopped? CMAJ (2008) 1.58
The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation. J Biol Chem (2004) 1.56
Pharmacokinetic parameters and tissue distribution of magnetic Fe(3)O(4) nanoparticles in mice. Int J Nanomedicine (2010) 1.51
The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2009) 1.51
Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. J Immunol (2005) 1.49
Sternal plating for primary and secondary sternal closure; can it improve sternal stability? J Cardiothorac Surg (2009) 1.49
Angiogenic actions of angiopoietin-1 require endothelium-derived nitric oxide. Am J Pathol (2003) 1.48
A median sternotomy approach to right extrapleural pneumonectomy for mesothelioma. Ann Thorac Surg (2005) 1.45
Update on blood conservation for cardiac surgery. J Cardiothorac Vasc Anesth (2011) 1.45
The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code. J Biol Chem (2005) 1.44
Acute surgical anemia influences the cardioprotective effects of beta-blockade: a single-center, propensity-matched cohort study. Anesthesiology (2010) 1.44
The Janus faces of iNOS. Circ Res (2003) 1.43
Pro: Aprotinin has a good efficacy and safety profile relative to other alternatives for prevention of bleeding in cardiac surgery. Anesth Analg (2006) 1.42
Abnormalities in villin gene expression and canalicular microvillus structure in progressive cholestatic liver disease of childhood. Lancet (2003) 1.41
Trauma and tribulation: the experiences and attitudes of operating room nurses working with organ donors. J Clin Nurs (2004) 1.41
Pathology and new players in the pathogenesis of brain edema. Acta Neuropathol (2009) 1.39
MicroRNA-145 targeted therapy reduces atherosclerosis. Circulation (2012) 1.39
Time of day modulates low-temperature Ca signals in Arabidopsis. Plant J (2006) 1.39
A first-in-man study of percutaneous myocardial cryotreatment in nonrevascularizable patients with refractory angina. Catheter Cardiovasc Interv (2009) 1.38
Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma. Am J Physiol Lung Cell Mol Physiol (2009) 1.37
Endothelial nitric oxide synthase: a new paradigm for gene regulation in the injured blood vessel. Arterioscler Thromb Vasc Biol (2003) 1.35
CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules. J Immunol (2004) 1.33
Cell-based angiopoietin-1 gene therapy for acute lung injury. Am J Respir Crit Care Med (2007) 1.33
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am J Physiol Heart Circ Physiol (2008) 1.32
Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown. Acta Neuropathol (2007) 1.31
Phospho-akt expression is associated with a favorable outcome in non-small cell lung cancer. Clin Cancer Res (2005) 1.30
Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow. Am J Pathol (2007) 1.28
The application of Fe3O4 nanoparticles in cancer research: a new strategy to inhibit drug resistance. J Biomed Mater Res A (2007) 1.27
Increased body lead burden--cause or consequence of chronic renal insufficiency? N Engl J Med (2003) 1.27
Adiponectin and cardiovascular disease: state of the art? Am J Physiol Heart Circ Physiol (2006) 1.27
Epigenetic regulation of vascular endothelial gene expression. Circ Res (2008) 1.26
GAL4 GFP enhancer trap lines for analysis of stomatal guard cell development and gene expression. J Exp Bot (2008) 1.25
Lamivudine in late pregnancy to interrupt in utero transmission of hepatitis B virus: a systematic review and meta-analysis. Obstet Gynecol (2010) 1.25
Temporal response and localization of integrins beta1 and beta3 in the heart after myocardial infarction: regulation by cytokines. Circulation (2003) 1.23
Post-transcriptional regulation of endothelial nitric-oxide synthase by an overlapping antisense mRNA transcript. J Biol Chem (2004) 1.22
A model of low-level primary blast brain trauma results in cytoskeletal proteolysis and chronic functional impairment in the absence of lung barotrauma. J Neurotrauma (2011) 1.22
Hypoxia-inducible expression of a natural cis-antisense transcript inhibits endothelial nitric-oxide synthase. J Biol Chem (2007) 1.22
Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice. Circulation (2004) 1.22
Reciprocal regulation of angiopoietin-1 and angiopoietin-2 following myocardial infarction in the rat. Cardiovasc Res (2004) 1.21
Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. J Biol Chem (2009) 1.20
The effect of the perioperative blood transfusion and blood conservation in cardiac surgery Clinical Practice Guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices. J Extra Corpor Technol (2010) 1.19
The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest (2012) 1.18
Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. Am J Pathol (2011) 1.17
Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells. Int J Nanomedicine (2009) 1.17
Functional importance of Dicer protein in the adaptive cellular response to hypoxia. J Biol Chem (2012) 1.15
2012 update to the Society of Thoracic Surgeons guideline on use of antiplatelet drugs in patients having cardiac and noncardiac operations. Ann Thorac Surg (2012) 1.15
Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant. J Clin Invest (2005) 1.15
Increased angiopoietin2 expression is associated with endothelial apoptosis and blood-brain barrier breakdown. Lab Invest (2005) 1.15
Endothelial progenitor cells promote fracture healing in a segmental bone defect model. J Orthop Res (2010) 1.14
Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism. PLoS One (2010) 1.13