Published in J Nutr on October 01, 2006
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice. J Nutr (2008) 1.82
Impact of dietary polyphenols on carbohydrate metabolism. Int J Mol Sci (2010) 1.78
Beneficial effects of green tea: a literature review. Chin Med (2010) 1.44
Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase. J Biol Chem (2007) 1.43
Complementary and alternative medicine for the treatment of type 2 diabetes. Can Fam Physician (2009) 1.40
Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial. Br J Nutr (2008) 1.28
Diabetes mellitus and its correlates in an Iranian adult population. PLoS One (2011) 1.19
Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds. Evid Based Complement Alternat Med (2013) 1.16
Weight control and prevention of metabolic syndrome by green tea. Pharmacol Res (2010) 1.15
Green tea protects rats against autoimmune arthritis by modulating disease-related immune events. J Nutr (2008) 1.10
Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells. Cell Mol Immunol (2010) 1.08
Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice. J Agric Food Chem (2011) 1.08
Tea consumption and risk of type 2 diabetes: a meta-analysis of cohort studies. J Gen Intern Med (2009) 1.00
Health-promoting effects of green tea. Proc Jpn Acad Ser B Phys Biol Sci (2012) 0.96
20-Hydroxyecdysone decreases weight and hyperglycemia in a diet-induced obesity mice model. Am J Physiol Endocrinol Metab (2009) 0.95
Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice. Br J Nutr (2010) 0.94
Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice. Nutr Metab (Lond) (2012) 0.93
Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells. Nucleic Acids Res (2013) 0.92
Polyphenols and Glycemic Control. Nutrients (2016) 0.91
The effect of omega-3 on the serum visfatin concentration in patients with type II diabetes. J Res Med Sci (2011) 0.91
Green Tea (Camellia sinensis) Supplementation to Diabetic Rats Improves Serum and Hepatic Oxidative Stress Markers. Iran J Pharm Res (2013) 0.88
Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system. Pharmacol Rev (2014) 0.87
Encapsulated nanoepigallocatechin-3-gallate and elemental selenium nanoparticles as paradigms for nanochemoprevention. Int J Nanomedicine (2012) 0.86
Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases. J Med Chem (2014) 0.84
Inhibition of starch digestion by the green tea polyphenol, (-)-epigallocatechin-3-gallate. Mol Nutr Food Res (2012) 0.84
Considering maternal dietary modulators for epigenetic regulation and programming of the fetal epigenome. Nutrients (2015) 0.82
Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-κB-mediated mechanism. Mol Nutr Food Res (2012) 0.81
Green Tea Attenuates Oxidative Stress and Downregulates the Expression of Angiotensin II AT(1) Receptor in Renal and Hepatic Tissues of Streptozotocin-Induced Diabetic Rats. Evid Based Complement Alternat Med (2012) 0.80
A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins. Eur J Nutr (2011) 0.80
Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs. Clin Exp Metastasis (2010) 0.79
Vascular and metabolic actions of the green tea polyphenol epigallocatechin gallate. Curr Med Chem (2015) 0.79
Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins. Anal Chem (2011) 0.79
Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study. Sci Rep (2015) 0.78
Role of bioactive food components in diabetes prevention: effects on Beta-cell function and preservation. Nutr Metab Insights (2014) 0.78
Preventive role of green tea catechins from obesity and related disorders especially hypercholesterolemia and hyperglycemia. J Transl Med (2015) 0.77
Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration? Curr Neuropharmacol (2014) 0.76
Epigallocatechin gallate does not accelerate the early phase of liver regeneration after partial hepatectomy in rats. Dig Dis Sci (2013) 0.76
Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis. ScientificWorldJournal (2012) 0.75
The effects of omega-3 on blood pressure and the relationship between serum visfatin level and blood pressure in patients with type II diabetes. ARYA Atheroscler (2012) 0.75
Plant-Derived Compounds Targeting Pancreatic Beta Cells for the Treatment of Diabetes. Evid Based Complement Alternat Med (2015) 0.75
The Green Tea Polyphenol(-)-epigallocatechin-3-gallate and its beneficial roles in chronic kidney disease. J Transl Int Med (2016) 0.75
The effect of omega-3 supplements on antioxidant capacity in patients with type 2 diabetes. Int J Prev Med (2013) 0.75
In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state. Aging (Albany NY) (2016) 0.75
Therapeutic Potential of Epigallocatechin Gallate Nanodelivery Systems. Biomed Res Int (2017) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol (2005) 27.17
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Genomewide association study of leprosy. N Engl J Med (2009) 8.17
Mapping human genetic diversity in Asia. Science (2009) 7.40
In vivo genome editing using a high-efficiency TALEN system. Nature (2012) 7.11
Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006. Birth Defects Res A Clin Mol Teratol (2010) 7.00
Management of lung nodules detected by volume CT scanning. N Engl J Med (2009) 6.79
KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science (2003) 6.60
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A (2009) 4.25
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis (2002) 4.23
The SOL Genomics Network: a comparative resource for Solanaceae biology and beyond. Plant Physiol (2005) 3.65
Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. Ann Neurol (2003) 3.54
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography. Genome Res (2006) 3.53
Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats. Stroke (2004) 3.53
The value of resident presentations at scientific meetings. Laryngoscope (2013) 3.48
Draft genome sequence of chickpea (Cicer arietinum) provides a resource for trait improvement. Nat Biotechnol (2013) 3.41
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc Natl Acad Sci U S A (2004) 3.40
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One (2008) 3.25
Combined ultrasound and optoacoustic system for real-time high-contrast vascular imaging in vivo. IEEE Trans Med Imaging (2005) 3.19
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell (2005) 3.15
Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Am J Psychiatry (2007) 2.84
Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation. Blood (2009) 2.82
Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration. Proc Natl Acad Sci U S A (2008) 2.65
Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression. Nat Med (2006) 2.57
Experimental evidence for epitaxial silicene on diboride thin films. Phys Rev Lett (2012) 2.56
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses. N Engl J Med (2014) 2.53
Macrophage autophagy plays a protective role in advanced atherosclerosis. Cell Metab (2012) 2.48
Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects. Am J Physiol Lung Cell Mol Physiol (2002) 2.46
Exploration of gene-gene interaction effects using entropy-based methods. Eur J Hum Genet (2007) 2.42
Activated neural stem cells contribute to stroke-induced neurogenesis and neuroblast migration toward the infarct boundary in adult rats. J Cereb Blood Flow Metab (2004) 2.41
Retracted Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. Am J Respir Crit Care Med (2012) 2.39
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res (2008) 2.38
Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: results from a randomized, multicenter, double-blinded, controlled study. Cephalalgia (2012) 2.38
MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-β1 pathway. Circulation (2012) 2.36
P25-graphene composite as a high performance photocatalyst. ACS Nano (2010) 2.34
Murine B7-H3 is a negative regulator of T cells. J Immunol (2004) 2.33
Vitellogenin, juvenile hormone, insulin signaling, and queen honey bee longevity. Proc Natl Acad Sci U S A (2007) 2.31
Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes. Clin Cancer Res (2013) 2.30
Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors. Cell Res (2008) 2.29
Self-assembly of CdTe nanocrystals into free-floating sheets. Science (2006) 2.25
Cerebral sinus venous thrombosis in Swiss children. Dev Med Child Neurol (2010) 2.25
Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke (2002) 2.24
The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer. J Clin Invest (2006) 2.18
Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction. Am J Epidemiol (2012) 2.16
Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. J Hepatol (2007) 2.16
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity (2009) 2.13
Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. J Biol Chem (2003) 2.12
Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV. J Clin Invest (2005) 2.08
Elafin is a biomarker of graft-versus-host disease of the skin. Sci Transl Med (2010) 2.08
Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia. J Cereb Blood Flow Metab (2006) 2.06
PD-L1 expression in triple-negative breast cancer. Cancer Immunol Res (2014) 2.06
Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration. J Neurosci (2006) 2.06
Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice. J Immunol (2009) 2.03
Development of a EST dataset and characterization of EST-SSRs in a traditional Chinese medicinal plant, Epimedium sagittatum (Sieb. Et Zucc.) Maxim. BMC Genomics (2010) 2.01
Lactate dehydrogenase B is critical for hyperactive mTOR-mediated tumorigenesis. Cancer Res (2011) 2.00
Impact of visual field loss on health-related quality of life in glaucoma: the Los Angeles Latino Eye Study. Ophthalmology (2007) 2.00
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Nature (2004) 1.99
Features of resolving and nonresolving indeterminate pulmonary nodules at follow-up CT: the NELSON study. Radiology (2013) 1.98
CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα. Cell Stem Cell (2012) 1.97
Regulatory divergence modifies limb length between mammals. Genes Dev (2008) 1.96
The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potent antiviral defense by two cooperative argonautes in Arabidopsis thaliana. Plant Cell (2011) 1.95
T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J (2006) 1.92
Distribution and speciation of heavy metals in sediments from the mainstream, tributaries, and lakes of the Yangtze River catchment of Wuhan, China. J Hazard Mater (2008) 1.89
Chemical characteristics of PM2.5 and PM10 in haze-fog episodes in Beijing. Environ Sci Technol (2006) 1.86
Role of Toll-like receptor 4 in endotoxin-induced acute renal failure. J Immunol (2004) 1.82
Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor. Proc Natl Acad Sci U S A (2008) 1.81
IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration. J Immunol (2012) 1.81
MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells. Proc Natl Acad Sci U S A (2010) 1.80
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest (2009) 1.80
Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice. J Orthop Res (2009) 1.76
Copper resistance is essential for virulence of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2011) 1.76
Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer. J Biol Chem (2011) 1.73
Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus. J Immunol (2007) 1.73
CD4+CD25+ regulatory T cells protect against injury in an innate murine model of chronic kidney disease. J Am Soc Nephrol (2006) 1.72
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell (2009) 1.72
A mammalian homolog of Drosophila tumorous imaginal discs, Tid1, mediates agrin signaling at the neuromuscular junction. Neuron (2008) 1.72
Accommodation and related risk factors associated with myopia progression and their interaction with treatment in COMET children. Invest Ophthalmol Vis Sci (2004) 1.69
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Neddylation plays an important role in the regulation of murine and human dendritic cell function. Blood (2013) 1.69
Anti-obesity effects of green tea: from bedside to bench. Mol Nutr Food Res (2006) 1.69
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet (2013) 1.68
PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer Res (2010) 1.65
Activation of MAPK kinase 9 induces ethylene and camalexin biosynthesis and enhances sensitivity to salt stress in Arabidopsis. J Biol Chem (2008) 1.64
Identification of outer membrane proteins of Mycobacterium tuberculosis. Tuberculosis (Edinb) (2008) 1.63
Pulmonary nodules detected at lung cancer screening: interobserver variability of semiautomated volume measurements. Radiology (2006) 1.63
β-Catenin is essential for Müllerian duct regression during male sexual differentiation. Development (2011) 1.62
Dietary surveys indicate vitamin intakes below recommendations are common in representative Western countries. Br J Nutr (2012) 1.61
Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis. Immunol Cell Biol (2011) 1.61
Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol (2006) 1.61
Inhibitory effect of the antimalarial agent artesunate on collagen-induced arthritis in rats through nuclear factor kappa B and mitogen-activated protein kinase signaling pathway. Transl Res (2012) 1.61
A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans. PLoS Biol (2008) 1.61
Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue. Mol Cell Biol (2005) 1.61
Fine mapping and identification of a candidate gene SSH1 in disseminated superficial actinic porokeratosis. Hum Mutat (2004) 1.59
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells. PLoS Biol (2012) 1.57
(De)constructing the ryanodine receptor: modeling ion permeation and selectivity of the calcium release channel. J Phys Chem B (2005) 1.57