Published in J Physiol on August 01, 1990
Block of native Ca(2+)-permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification. J Physiol (1995) 2.26
Neuronal nicotinic acetylcholine receptor currents in phaeochromocytoma (PC12) cells: dual mechanisms of rectification. J Physiol (1992) 1.37
The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. J Physiol (1997) 1.36
Mechanism of cGMP-gated channel block by intracellular polyamines. J Gen Physiol (2000) 1.34
Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones. J Physiol (1991) 1.33
On the excitatory effects of ATP and its role as a neurotransmitter in coeliac neurons of the guinea-pig. J Physiol (1993) 1.29
Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. J Physiol (1994) 1.27
5-HT3 receptor channels in dissociated rat superior cervical ganglion neurons. J Physiol (1992) 1.24
Comparison of quantitative calcium flux through NMDA, ATP, and ACh receptor channels. Biophys J (1995) 1.20
Calcium entry through nicotinic receptor channels and calcium channels in cultured rat superior cervical ganglion cells. J Physiol (1993) 1.18
Non-additive interaction between nicotinic cholinergic and P2X purine receptors in guinea-pig enteric neurons in culture. J Physiol (1998) 1.17
Ca2+ permeability of mouse and chick nicotinic acetylcholine receptors expressed in transiently transfected human cells. J Physiol (1998) 1.06
Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry. J Neurosci (2013) 1.02
Inward rectification of acetylcholine-elicited currents in rat phaeochromocytoma cells. J Physiol (1992) 1.02
Two distinct classes of functional 7-containing nicotinic receptor on rat superior cervical ganglion neurons. J Physiol (2000) 1.02
Nicotinic acetylcholine currents of cultured Kkenyon cells from the mushroom bodies of the honey bee Aapis mellifera. J Physiol (1999) 1.02
Effects of divalent cations on muscarinic receptor cationic current in smooth muscle from guinea-pig small intestine. J Physiol (1995) 1.01
Cognitive deficits in schizophrenia: focus on neuronal nicotinic acetylcholine receptors and smoking. Cell Mol Neurobiol (2007) 0.99
Actions of general anaesthetics on a neuronal nicotinic acetylcholine receptor in isolated identified neurones of Lymnaea stagnalis. Br J Pharmacol (1995) 0.98
Free intracellular Mg(2+) concentration and inhibition of NMDA responses in cultured rat neurons. J Physiol (2001) 0.97
A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture. J Physiol (1992) 0.96
Voltage-dependent block by magnesium of neuronal nicotinic acetylcholine receptor channels in rat phaeochromocytoma cells. J Physiol (1991) 0.95
Pharmacological and kinetic properties of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Physiol (1992) 0.94
Voltage-jump relaxation kinetics for wild-type and chimeric beta subunits of neuronal nicotinic receptors. J Gen Physiol (1996) 0.92
Heterogeneity of neuronal nicotinic acetylcholine receptors in thin slices of rat medial habenula. J Physiol (1995) 0.91
Activation and cooperative multi-ion block of single nicotinic-acetylcholine channel currents of Ascaris muscle by the tetrahydropyrimidine anthelmintic, morantel. Br J Pharmacol (1996) 0.88
Dequalinium: a novel, high-affinity blocker of CNGA1 channels. J Gen Physiol (2003) 0.86
An alpha3beta4 subunit combination acts as a major functional nicotinic acetylcholine receptor in male rat pelvic ganglion neurons. Pflugers Arch (2006) 0.85
Multiple modes of α7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents. Mol Pharmacol (2013) 0.82
Modulation of acetylcholine-elicited currents in clonal rat phaeochromocytoma (PC12) cells by internal polyphosphates. J Physiol (1993) 0.82
Nicotinic acetylcholine receptors in attention circuitry: the role of layer VI neurons of prefrontal cortex. Cell Mol Life Sci (2014) 0.82
Inhibition by cyclothiazide of neuronal nicotinic responses in bovine chromaffin cells. Br J Pharmacol (1995) 0.80
An electrophysiological study of muscarinic and nicotinic receptors of rat paratracheal ganglion neurons and their inhibition by Z-338. Br J Pharmacol (2002) 0.79
Regulation of the sensitivity of acetylcholine receptors to nicotine in rat habenula neurons. J Physiol (2000) 0.79
Modeling study of mecamylamine block of muscle type acetylcholine receptors. Eur Biophys J (2007) 0.77
Nicotinic effects on excitatory field potentials recorded from the immature CA3 area of rat hippocampal slices. Exp Brain Res (2003) 0.75
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch (1981) 134.60
A study of the desensitization produced by acetylcholine at the motor end-plate. J Physiol (1957) 15.07
A quantitative description of end-plate currents. J Physiol (1972) 11.27
A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine. J Physiol (1982) 10.42
Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. J Physiol (1985) 9.25
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones. Nature (1984) 9.22
Active phase of frog's end-plate potential. J Neurophysiol (1959) 9.13
The effect of voltage on the time course of end-plate currents. J Physiol (1972) 8.24
Fluctuations in the microsecond time range of the current through single acetylcholine receptor ion channels. Nature (1981) 7.16
Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature (1980) 6.83
Paralysis of autonomic ganglia by methonium salts. Br J Pharmacol Chemother (1951) 6.21
Ohmic conductance through the inwardly rectifying K channel and blocking by internal Mg2+. Nature (1987) 5.44
Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions. Proc Natl Acad Sci U S A (1987) 5.12
Voltage dependence of agonist effectiveness at the frog neuromuscular junction: resolution of a paradox. J Physiol (1975) 5.09
The actions of tubocurarine at the frog neuromuscular junction. J Physiol (1979) 3.69
The effect of membrane polarization on the time course of the end-plate current in frog sartorius muscle. J Physiol (1969) 3.49
Activation of ion channels in the frog end-plate by high concentrations of acetylcholine. J Physiol (1988) 3.19
Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques: a study of neurally evoked postsynaptic currents and of voltage-jump relaxations. J Gen Physiol (1977) 2.86
Desensitization at the frog neuromuscular junction: a biphasic process. J Physiol (1982) 2.31
Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques. J Gen Physiol (1975) 2.19
Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit. Nature (1986) 2.13
Substance P reduces acetylcholine-induced currents in isolated bovine chromaffin cells. J Physiol (1984) 2.09
How many kinds of nicotinic acetylcholine receptor are there? Trends Neurosci (1989) 1.92
Developmental regulation of nicotinic acetylcholine receptors. Annu Rev Neurosci (1987) 1.80
Inhibitory post-synaptic currents in rat hippocampal CA1 neurones. J Physiol (1984) 1.79
Characteristics of fast excitatory postsynaptic current in bullfrog sympathetic ganglion cells. Effects of membrane potential, temperature and Ca ions. Pflugers Arch (1979) 1.70
Role of acetylcholine receptor subunits in gating of the channel. Nature (1986) 1.63
Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. J Physiol (1989) 1.48
Effect of acetylcholine on postjunctional membrane permeability in eel electroplaque. J Gen Physiol (1977) 1.46
The action of ganglionic blocking drugs on the synaptic responses of rat submandibular ganglion cells. Br J Pharmacol (1982) 1.46
Acetylcholine-induced current fluctuations and fast excitatory post-synaptic currents in rabbit sympathetic neurones. J Physiol (1983) 1.41
Single-channel and whole-cell currents evoked by acetylcholine in dissociated sympathetic neurons of the rat. Proc R Soc Lond B Biol Sci (1987) 1.40
A comparison of current-voltage relations for full and partial agonists. J Physiol (1978) 1.32
Monitoring cytosolic free magnesium in cultured chicken heart cells by use of the fluorescent indicator Furaptra. Proc Natl Acad Sci U S A (1989) 1.28
Acetylcholine dose-response relation and the effect of cesium ions in the rat adrenal chromaffin cell under voltage clamp. Pflugers Arch (1987) 1.21
An analysis of the inhibitory post-synaptic current in the voltage-clamped crayfish muscle. J Physiol (1979) 1.21
Synaptic electrogenesis in eel electroplaques. J Gen Physiol (1971) 1.20
Post-natal development of ganglia in the lower lumbar sympathetic chain of the rat. J Physiol (1984) 1.17
Molecular studies of the neuronal nicotinic acetylcholine receptor family. Mol Neurobiol (1987) 1.16
The properties and regulation of functional acetylcholine receptors on chick ciliary ganglion neurons. J Neurosci (1987) 1.10
Single channels activated by acetylcholine in rat superior cervical ganglion. J Physiol (1987) 1.09
Membrane potential modulates the activation of GABA-gated channels. J Neurophysiol (1988) 1.07
Fast excitatory postsynaptic currents in voltage-clamped mammalian sympathetic ganglion neurones. J Auton Nerv Syst (1979) 1.04
Junctional and extrajunctional membrane channels activated by GABA in locust muscle fibres. Proc R Soc Lond B Biol Sci (1981) 1.01
Acetylcholine receptor channels and their block by clonidine in cultured bovine chromaffin cells. J Physiol (1988) 0.96
Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum. Nature (1984) 0.95
Ion channels activated by acetylcholine and gamma-aminobutyric acid in freshly dissociated sympathetic neurones of the rat. Neurosci Lett (1986) 0.91
Actions of snake venom toxins on neuronal nicotinic receptors and other neuronal receptors. Pharmacol Ther (1985) 0.87
The ultrastructural distribution of putative nicotinic receptors on cultured neurons from the rat superior cervical ganglion. Neuroscience (1988) 0.87
Changes in intracellular free magnesium during hypoglycaemia and hypoxia in cerebral tissue as calculated from 31P-nuclear magnetic resonance spectra. J Neurochem (1989) 0.85
[The potential dependence of acetylcholine-activated membrane conductance in sympathetic ganglion neurons]. Neirofiziologiia (1988) 0.82
Acetylcholine receptor: channel-opening kinetics evaluated by rapid chemical kinetic and single-channel current measurements. Biophys J (1987) 0.81
Nicotinic acetylcholine receptors in the neurones of autonomic ganglia. J Auton Nerv Syst (1987) 0.80
On the stochastic properties of single ion channels. Proc R Soc Lond B Biol Sci (1981) 11.30
Relaxation and fluctuations of membrane currents that flow through drug-operated channels. Proc R Soc Lond B Biol Sci (1977) 10.37
Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. J Physiol (1985) 9.25
On the stochastic properties of bursts of single ion channel openings and of clusters of bursts. Philos Trans R Soc Lond B Biol Sci (1982) 7.45
Fluctuations in the microsecond time range of the current through single acetylcholine receptor ion channels. Nature (1981) 7.16
Inward current channels activated by intracellular Ca in cultured cardiac cells. Nature (1981) 6.62
A P2X purinoceptor expressed by a subset of sensory neurons. Nature (1995) 4.86
ATP receptor-mediated synaptic currents in the central nervous system. Nature (1992) 4.57
Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature (2001) 4.32
The actions of tubocurarine at the frog neuromuscular junction. J Physiol (1979) 3.69
Conductance of channels opened by acetylcholine-like drugs in muscle end-plate. Nature (1975) 3.64
Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors. J Physiol (1996) 3.60
The binding of labelled tetrodotoxin to non-myelinated nerve fibres. J Physiol (1972) 3.60
Multiple-conductance channels activated by excitatory amino acids in cerebellar neurons. Nature (1987) 3.55
Acetylcholine receptors: too many channels, too few functions. Science (1995) 3.55
Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype. Nature (2000) 3.27
Single-channel properties of recombinant AMPA receptors depend on RNA editing, splice variation, and subunit composition. J Neurosci (1997) 2.80
Intracellular spermine confers rectification on rat calcium-permeable AMPA and kainate receptors. J Physiol (1995) 2.64
Ion channel block by acetylcholine, carbachol and suberyldicholine at the frog neuromuscular junction. Proc R Soc Lond B Biol Sci (1985) 2.64
Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proc Biol Sci (1992) 2.49
Non-NMDA glutamate receptor occupancy and open probability at a rat cerebellar synapse with single and multiple release sites. J Physiol (1996) 2.34
Rapid kinetics of single glutamate-receptor channels. Nature (1982) 2.33
Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons. Nature (1990) 2.33
Asymptotic distributions of apparent open times and shut times in a single channel record allowing for the omission of brief events. Philos Trans R Soc Lond B Biol Sci (1992) 2.32
An analysis of the action of a false transmitter at the neuromuscular junction. J Physiol (1977) 2.29
A note on correlations in single ion channel records. Proc R Soc Lond B Biol Sci (1987) 2.26
Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. J Physiol (1998) 2.26
Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature (1992) 2.26
Locus of frequency-dependent depression identified with multiple-probability fluctuation analysis at rat climbing fibre-Purkinje cell synapses. J Physiol (1998) 2.24
Activation of N-methyl-D-aspartate receptors by L-glutamate in cells dissociated from adult rat hippocampus. J Physiol (1992) 2.24
Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse. Neuron (1993) 2.08
Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits. J Physiol (2003) 1.99
Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum. J Physiol (1995) 1.81
Re-analysis of clinical trial of homoeopathic treatment in fibrositis. Lancet (1990) 1.81
Two types of extrajunctional L-glutamate receptors in locust muscle fibres. J Physiol (1976) 1.80
Effects of botulinum toxin on neuromuscular transmission in the rat. J Physiol (1976) 1.78
Complementary medicine in the medical curriculum. J R Soc Med (1997) 1.75
The binding of tetrodotoxin and alpha-bungarotoxin to normal and denervated mammalian muscle. J Physiol (1974) 1.73
Single-channel properties of synaptic and extrasynaptic GABAA receptors suggest differential targeting of receptor subtypes. J Neurosci (1999) 1.73
On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat. J Physiol (1992) 1.65
Identification of a native low-conductance NMDA channel with reduced sensitivity to Mg2+ in rat central neurones. J Physiol (1996) 1.65
Single-channel currents from recombinant NMDA NR1a/NR2D receptors expressed in Xenopus oocytes. Proc Biol Sci (1996) 1.65
Single glutamate-activated channels recorded from locust muscle fibres with perfused patch-clamp electrodes. J Physiol (1981) 1.62
Pharmacological properties and H+ sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones. J Physiol (1991) 1.60
Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour. J Physiol (1997) 1.60
The interaction at equilibrium between tetrodotoxin and mammalian non-myelinated nerve fibres. J Physiol (1972) 1.58
Ion channels activated by L-glutamate and GABA in cultured cerebellar neurons of the rat. Proc R Soc Lond B Biol Sci (1985) 1.57
NMDA-receptor channel diversity in the developing cerebellum. Nature (1994) 1.57
Effects of pravastatin in 3260 patients with unstable angina: results from the LIPID study. Lancet (2000) 1.56
Mechanisms of activation of muscle nicotinic acetylcholine receptors and the time course of endplate currents. Annu Rev Physiol (1995) 1.55
On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons. Proc R Soc Lond B Biol Sci (1988) 1.52
Mechanisms of activation of glutamate receptors and the time course of excitatory synaptic currents. Annu Rev Physiol (1995) 1.51
Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells. J Physiol (1991) 1.51
Conductances of single ion channels opened by nicotinic agonists are indistinguishable. Nature (1984) 1.50
Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors. J Physiol (1996) 1.49
Mechanisms of drug action at the voluntary muscle endplate. Annu Rev Pharmacol (1975) 1.49
Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. J Physiol (1989) 1.48
Block of acetylcholine-activated ion channels by an uncharged local anaesthetic. Nature (1981) 1.47
The action of ganglionic blocking drugs on the synaptic responses of rat submandibular ganglion cells. Br J Pharmacol (1982) 1.46
The modes of action of gallamine. Proc R Soc Lond B Biol Sci (1981) 1.45
End-plate currents and acetylcholine noise at normal and myasthenic human end-plates. J Physiol (1979) 1.42
Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum. J Neurosci (1996) 1.41
Single-channel and whole-cell currents evoked by acetylcholine in dissociated sympathetic neurons of the rat. Proc R Soc Lond B Biol Sci (1987) 1.40
The kinetics of the interaction between tetrodotoxin and mammalian nonmyelinated nerve fibers. Mol Pharmacol (1972) 1.39
Glutamate current noise: post-synaptic channel kinetics investigated under voltage clamp. J Physiol (1978) 1.38
Identification of subunits contributing to synaptic and extrasynaptic NMDA receptors in Golgi cells of the rat cerebellum. J Physiol (2000) 1.37
The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. J Physiol (1997) 1.36
Effects of inhibitors of the binding of iodinated alpha-bungarotoxin to acetylcholine receptors in rat muscle. Mol Pharmacol (1976) 1.36
Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors. Proc Biol Sci (1995) 1.35
On the release of transmitter at normal, myasthenia gravis and myasthenic syndrome affected human end-plates. J Physiol (1980) 1.34
Glutamate activation of a single NMDA receptor-channel produces a cluster of channel openings. Proc Biol Sci (1991) 1.34
Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones. J Physiol (1991) 1.33
Multiple conductance channels in type-2 cerebellar astrocytes activated by excitatory amino acids. Nature (1989) 1.33
Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. J Neurosci (1998) 1.32
Two populations of L-glutamate receptors on locust muscle fibres. Nat New Biol (1973) 1.32
Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells. J Physiol (2000) 1.31
Glutamate and quisqualate noise in voltage-clamped locust muscle fibres. Nature (1976) 1.29
A direct comparison of the single-channel properties of synaptic and extrasynaptic NMDA receptors. J Neurosci (1997) 1.27
Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. J Physiol (1994) 1.27
Deactivation and desensitization of non-NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells. J Physiol (1996) 1.26
The efficacy of agonists at the frog neuromuscular junction studied with single channel recording. Pflugers Arch (1983) 1.23
Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices. Proc Biol Sci (1991) 1.23
Expression of cloned receptor subunits produces multiple receptors. Proc Biol Sci (1990) 1.21
A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor. J Biol Chem (1998) 1.21
Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes. J Physiol (1998) 1.20
Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat. J Physiol (1991) 1.17
Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures. J Physiol (1991) 1.17
Rapid decay of averaged single-channel NMDA receptor activations recorded at low agonist concentration. Proc Biol Sci (1992) 1.17
Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum. Neuroscience (2009) 1.14
Rapid histamine assays: a method and some theoretical considerations. Br J Pharmacol (1970) 1.14
Single channel properties of cloned NMDA receptors in a human cell line: comparison with results from Xenopus oocytes. J Physiol (1994) 1.14
Long-term risk stratification for survivors of acute coronary syndromes. Results from the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study. LIPID Study Investigators. J Am Coll Cardiol (2001) 1.14
Passive sensitization of skin and lung by guinea-pig immunoglobulins. Immunology (1965) 1.13
Adsorption and diffusion of gamma-globulin during passive sensitization of chopped guinea-pig lung. J Physiol (1965) 1.12