Published in Cancer Lett on September 25, 2006
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat Rev Cancer (2008) 4.71
Reciprocal influence of the p53 and the hypoxic pathways. Cell Death Dis (2011) 1.60
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Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. Mol Cell (2014) 1.21
A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer. J Pharmacol Exp Ther (2015) 0.80
A combined gene signature of hypoxia and notch pathway in human glioblastoma and its prognostic relevance. PLoS One (2015) 0.79
SOCS3 modulates interleukin-6R signaling preference in dermal fibroblasts. J Interferon Cytokine Res (2012) 0.78
The relationship of the angiogenesis regulators VEGF-A, VEGF-R1 and VEGF-R2 to p53 status and prognostic factors in epithelial ovarian carcinoma in FIGO-stages I-II. Int J Oncol (2016) 0.78
Identification of novel drugs to target dormant micrometastases. BMC Cancer (2015) 0.77
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Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation (2002) 6.26
Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients. Diabetes (2008) 4.05
Effects of long-term selenium supplementation on the incidence of type 2 diabetes: a randomized trial. Ann Intern Med (2007) 3.67
How do we define cure of diabetes? Diabetes Care (2009) 3.59
Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation. Diabetes (2003) 3.20
Effects of a Mediterranean-style diet on the need for antihyperglycemic drug therapy in patients with newly diagnosed type 2 diabetes: a randomized trial. Ann Intern Med (2009) 3.16
Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation (2008) 2.65
Clinical review 2: The "metabolic memory": is more than just tight glucose control necessary to prevent diabetic complications? J Clin Endocrinol Metab (2008) 2.21
Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells. Cancer Res (2010) 1.91
The effects of diet on inflammation: emphasis on the metabolic syndrome. J Am Coll Cardiol (2006) 1.83
Intermittent high glucose enhances ICAM-1, VCAM-1 and E-selectin expression in human umbilical vein endothelial cells in culture: the distinct role of protein kinase C and mitochondrial superoxide production. Atherosclerosis (2005) 1.66
Constant and intermittent high glucose enhances endothelial cell apoptosis through mitochondrial superoxide overproduction. Diabetes Metab Res Rev (2006) 1.63
Laparoscopic splenectomy: a single center experience. Unusual cases and expanded inclusion criteria for laparoscopic approach. Updates Surg (2013) 1.54
Cardiovascular health in migrants: current status and issues for prevention. A collaborative multidisciplinary task force report. J Cardiovasc Med (Hagerstown) (2014) 1.50
Post-meal glucose peaks at home associate with carotid intima-media thickness in type 2 diabetes. J Clin Endocrinol Metab (2008) 1.49
Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Environ Health Perspect (2009) 1.48
Postprandial hyperglycemia and glycemic variability: should we care? Diabetes Care (2011) 1.46
Addressing schemes of self-monitoring of blood glucose in type 2 diabetes: a European perspective and expert recommendation. Diabetes Technol Ther (2011) 1.43
Chemoenzymatic synthesis with distinct Pasteurella heparosan synthases: monodisperse polymers and unnatural structures. J Biol Chem (2007) 1.43
High fat intake leads to acute postprandial exposure to circulating endotoxin in type 2 diabetic subjects. Diabetes Care (2011) 1.43
Intraretinal leakage and oxidation of LDL in diabetic retinopathy. Invest Ophthalmol Vis Sci (2008) 1.42
Intensive structured self-monitoring of blood glucose and glycemic control in noninsulin-treated type 2 diabetes: the PRISMA randomized trial. Diabetes Care (2013) 1.42
Addition of neutral protamine lispro insulin or insulin glargine to oral type 2 diabetes regimens for patients with suboptimal glycemic control: a randomized trial. Ann Intern Med (2008) 1.40
Oxidative stress in diabetes. Clin Chem Lab Med (2003) 1.38
Arsenic stimulates angiogenesis and tumorigenesis in vivo. Toxicol Sci (2003) 1.35
Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung. Chem Biol Interact (2008) 1.34
Diabetes Interactive Diary: a new telemedicine system enabling flexible diet and insulin therapy while improving quality of life: an open-label, international, multicenter, randomized study. Diabetes Care (2009) 1.31
Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents. Bioorg Med Chem (2010) 1.30
Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring. BMC Genomics (2009) 1.29
Efficacy of insulin analogs in achieving the hemoglobin A1c target of <7% in type 2 diabetes: meta-analysis of randomized controlled trials. Diabetes Care (2011) 1.26
Glucose metabolism and hyperglycemia. Am J Clin Nutr (2008) 1.26
Postprandial glucose regulation: new data and new implications. Clin Ther (2005) 1.22
Enteral nutritional support and use of diabetes-specific formulas for patients with diabetes: a systematic review and meta-analysis. Diabetes Care (2005) 1.21
Role of HIF signaling on tumorigenesis in response to chronic low-dose arsenic administration. Toxicol Sci (2005) 1.19
Prevention and control of type 2 diabetes by Mediterranean diet: a systematic review. Diabetes Res Clin Pract (2010) 1.18
The ubiquitin-proteasome system and inflammatory activity in diabetic atherosclerotic plaques: effects of rosiglitazone treatment. Diabetes (2006) 1.16
Exposure to arsenic at levels found inU.S. drinking water modifies expression in the mouse lung. Toxicol Sci (2007) 1.13
Self-monitoring of blood glucose in type 2 diabetes: recent studies. J Diabetes Sci Technol (2013) 1.11
Does personalized diabetology overcome clinical uncertainty and therapeutic inertia in type 2 diabetes? Endocrine (2013) 1.09
Antiangiogenic and antitumor agents. Design, synthesis, and evaluation of novel 2-amino-4-(3-bromoanilino)-6-benzylsubstituted pyrrolo[2,3-d]pyrimidines as inhibitors of receptor tyrosine kinases. Bioorg Med Chem (2003) 1.09
Glucose variability: An emerging target for the treatment of diabetes mellitus. Diabetes Res Clin Pract (2013) 1.05
Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole. PLoS One (2011) 1.04
Cardiovascular risk assessment in low-resource settings: a consensus document of the European Society of Hypertension Working Group on Hypertension and Cardiovascular Risk in Low Resource Settings. J Hypertens (2014) 1.04
High-glycemic index carbohydrate increases nuclear factor-kappaB activation in mononuclear cells of young, lean healthy subjects. Am J Clin Nutr (2008) 1.04
The effect of glucose variability on the risk of microvascular complications in type 1 diabetes. Diabetes Care (2007) 1.03
Advanced glycation end products and antioxidant status in type 2 diabetic patients with and without peripheral artery disease. Diabetes Care (2007) 1.00
Effect of rosiglitazone on endothelial function and inflammatory markers in patients with the metabolic syndrome. Diabetes Care (2006) 0.98
The importance of glycated haemoglobin (HbA(1c)) and postprandial glucose (PPG) control on cardiovascular outcomes in patients with type 2 diabetes. Diabetes Res Clin Pract (2010) 0.96
Post hoc subgroup analysis of the HEART2D trial demonstrates lower cardiovascular risk in older patients targeting postprandial versus fasting/premeal glycemia. Diabetes Care (2011) 0.96
Are there specific treatments for the metabolic syndrome? Am J Clin Nutr (2008) 0.96
Docosahexaenoic acid inhibits superoxide dismutase 1 gene transcription in human cancer cells: the involvement of peroxisome proliferator-activated receptor alpha and hypoxia-inducible factor-2alpha signaling. Mol Pharmacol (2009) 0.95
Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism. Anesthesiology (2008) 0.95
Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin. Diabetes (2010) 0.94
Type 1 diabetes and cardiovascular disease. Cardiovasc Diabetol (2013) 0.94
Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes. Aging (Albany NY) (2013) 0.94
A novel multidrug resistance phenotype of bladder tumor cells grown on Matrigel or SIS gel. Cancer Lett (2005) 0.94
Chemoenzymatic synthesis of uridine diphosphate-GlcNAc and uridine diphosphate-GalNAc analogs for the preparation of unnatural glycosaminoglycans. J Org Chem (2012) 0.93
Regulatory network of inflammation downstream of proteinase-activated receptors. BMC Physiol (2007) 0.93
Antioxidant therapy in diabetic complications: what is new? Curr Vasc Pharmacol (2004) 0.92
Point: postprandial glucose levels are a clinically important treatment target. Diabetes Care (2010) 0.92
Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation. BMC Physiol (2007) 0.91
Postprandial hyperglycemia and cardiovascular disease: is the HEART2D study the answer? Diabetes Care (2009) 0.91
Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell proliferation. Biol Pharm Bull (2002) 0.91
Enhanced angiogenesis of modified porcine small intestinal submucosa with hyaluronic acid-poly(lactide-co-glycolide) nanoparticles: from fabrication to preclinical validation. J Biomed Mater Res A (2010) 0.90
Identifying patients with type 2 diabetes at high risk of microalbuminuria: results of the DEMAND (Developing Education on Microalbuminuria for Awareness of reNal and cardiovascular risk in Diabetes) Study. Nephrol Dial Transplant (2007) 0.89
A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function. J Biol Chem (2014) 0.89
GLP-1 analogue, Liraglutide protects human umbilical vein endothelial cells against high glucose induced endoplasmic reticulum stress. Regul Pept (2011) 0.88
Laparoscopic vs. open surgery for treating benign liver lesions: assessing quality of life in the first year after surgery. Updates Surg (2014) 0.88
The protective effect of rosuvastatin in human umbilical endothelial cells exposed to constant or intermittent high glucose. J Diabetes Complications (2008) 0.87
Primary role of superoxide anion generation in the cascade of events leading to endothelial dysfunction and damage in high glucose treated HUVEC. Nutr Metab Cardiovasc Dis (2006) 0.87
Molecular targets of diabetic vascular complications and potential new drugs. Curr Drug Targets (2005) 0.87
Structure/function analysis of Pasteurella multocida heparosan synthases: toward defining enzyme specificity and engineering novel catalysts. J Biol Chem (2012) 0.87
Prospective, randomized trial on intensive SMBG management added value in non-insulin-treated T2DM patients (PRISMA): a study to determine the effect of a structured SMBG intervention. Acta Diabetol (2011) 0.87
Segmentectomy: is minimally invasive surgery going to change a liver dogma? Updates Surg (2015) 0.86
Kidney dysfunction and related cardiovascular risk factors among patients with type 2 diabetes. Nephrol Dial Transplant (2014) 0.85
Management of hyperglycemia in type 2 diabetes: evidence and uncertainty. Cardiovasc Diabetol (2013) 0.85
Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation. BMC Immunol (2007) 0.85
Pathogenetic loop between diabetes and cell senescence. Diabetes Care (2007) 0.85
The role of self-monitoring of blood glucose in glucagon-like peptide-1-based treatment approaches: a European expert recommendation. J Diabetes Sci Technol (2012) 0.84
Diet and the metabolic syndrome. Metab Syndr Relat Disord (2007) 0.83
Design, synthesis and biological evaluation of substituted pyrrolo[2,3-d]pyrimidines as multiple receptor tyrosine kinase inhibitors and antiangiogenic agents. Bioorg Med Chem (2008) 0.83
Self-monitoring of blood glucose in type 2 diabetes: is the debate (finally) ending? Diabetes Res Clin Pract (2012) 0.82
N-sulfotestosteronan, a novel substrate for heparan sulfate 6-o-sulfotransferases and its analysis by oxidative degradation. Biopolymers (2013) 0.82
Remission of type 2 diabetes after Roux-en-Y gastric bypass or sleeve gastrectomy is associated with a distinct glycemic profile. Ann Surg (2015) 0.82
Suppression and activation of the malignant phenotype by extracellular matrix in xenograft models of bladder cancer: a model for tumor cell "dormancy". PLoS One (2013) 0.82
Time is glucose, can't miss gestational diabetes. Diabetes Technol Ther (2012) 0.81
Effect of a single high-fat meal on endothelial function in patients with the metabolic syndrome: role of tumor necrosis factor-alpha. Nutr Metab Cardiovasc Dis (2006) 0.81
Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro. J Nutr Biochem (2011) 0.81