PubRank

C Jane McGlade

Author PubWeight™ 56.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol 2002 4.89
2 Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis. Nature 2002 3.22
3 Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B. Dev Cell 2002 2.99
4 Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J Biol Chem 2003 2.94
5 Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc Natl Acad Sci U S A 2003 2.89
6 The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. Curr Biol 2002 2.02
7 Numb regulates post-endocytic trafficking and degradation of Notch1. J Biol Chem 2009 1.89
8 aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb. EMBO J 2007 1.81
9 The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size. Dev Cell 2006 1.67
10 Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer. Mol Cell Biol 2010 1.53
11 A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling. Curr Biol 2002 1.49
12 Yurt, Coracle, Neurexin IV and the Na(+),K(+)-ATPase form a novel group of epithelial polarity proteins. Nature 2009 1.35
13 The cell fate determinant numb interacts with EHD/Rme-1 family proteins and has a role in endocytic recycling. Mol Biol Cell 2004 1.34
14 LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation. EMBO J 2002 1.31
15 Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition. Mol Cell 2003 1.24
16 The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo. Development 2007 1.21
17 A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas. J Exp Med 2011 1.13
18 PTP1B and TC-PTP: novel roles in immune-cell signaling. Can J Physiol Pharmacol 2006 1.11
19 The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascades. J Exp Med 2004 1.05
20 Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membrane. Mol Biol Cell 2006 1.04
21 T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation. Mol Cell Biol 2006 1.02
22 Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification. J Immunol 2002 0.98
23 Cluster analysis of protein array results via similarity of Gene Ontology annotation. BMC Bioinformatics 2006 0.98
24 Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif. EMBO J 2007 0.93
25 The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor. J Cell Sci 2013 0.92
26 Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb. Mol Cell Proteomics 2012 0.91
27 Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells. Mol Cell Biol 2003 0.90
28 Numb regulates Notch1, but not Notch3, during myogenesis. Mech Dev 2011 0.90
29 Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling. Mol Cell Biol 2002 0.88
30 LNX1 is a perisynaptic Schwann cell specific E3 ubiquitin ligase that interacts with ErbB2. Mol Cell Neurosci 2005 0.87
31 A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb. J Biol Chem 2004 0.87
32 Divergent lymphocyte signalling revealed by a powerful new tool for analysis of time-lapse microscopy. Immunol Cell Biol 2012 0.86
33 The Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation. J Biol Chem 2007 0.85
34 Phosphatidylinositol 3'-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells. Neuro Oncol 2002 0.85
35 The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. J Immunol 2011 0.84
36 Biochemical and computational analysis of LNX1 interacting proteins. PLoS One 2011 0.82
37 Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation. Exp Cell Res 2010 0.82
38 Overexpression of human CRB1 or related isoforms, CRB2 and CRB3, does not regulate the human presenilin complex in culture cells. Biochemistry 2007 0.80
39 Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through β-sheet formation. Cell Signal 2013 0.78
40 Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v. Oncogene 2003 0.77
41 Comprehensive identification of phosphorylation sites on the Numb endocytic adaptor protein. Proteomics 2015 0.77
42 Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest 2017 0.75