Published in J Biol Chem on October 03, 2006
Physiology and function of the tight junction. Cold Spring Harb Perspect Biol (2009) 3.06
Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex. J Clin Invest (2008) 2.24
Biology of claudins. Am J Physiol Renal Physiol (2008) 2.17
Claudins and the modulation of tight junction permeability. Physiol Rev (2013) 2.05
Renal salt wasting and chronic dehydration in claudin-7-deficient mice. Am J Physiol Renal Physiol (2009) 1.90
Claudin-4 augments alveolar epithelial barrier function and is induced in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2009) 1.56
Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol Biol Cell (2008) 1.53
Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine. Proc Natl Acad Sci U S A (2010) 1.52
Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization. Proc Natl Acad Sci U S A (2010) 1.36
CLDN16 genotype predicts renal decline in familial hypomagnesemia with hypercalciuria and nephrocalcinosis. J Am Soc Nephrol (2007) 1.35
A claudin-9-based ion permeability barrier is essential for hearing. PLoS Genet (2009) 1.29
Claudin-1 is a p63 target gene with a crucial role in epithelial development. PLoS One (2008) 1.20
Regulation of transport in the connecting tubule and cortical collecting duct. Compr Physiol (2012) 1.16
Claudins and the kidney. Annu Rev Physiol (2012) 1.11
A key claudin extracellular loop domain is critical for epithelial barrier integrity. Am J Pathol (2008) 1.09
Symplekin promotes tumorigenicity by up-regulating claudin-2 expression. Proc Natl Acad Sci U S A (2010) 1.08
Changes in mucosal homeostasis predispose NHE3 knockout mice to increased susceptibility to DSS-induced epithelial injury. Gastroenterology (2009) 1.08
Cell adhesion molecules in chemically-induced renal injury. Pharmacol Ther (2007) 1.06
Minimal effects of VEGF and anti-VEGF drugs on the permeability or selectivity of RPE tight junctions. Invest Ophthalmol Vis Sci (2009) 1.04
Regulation of tight junction assembly and epithelial polarity by a resident protein of apical endosomes. Traffic (2010) 1.02
The blood-brain barrier. Cold Spring Harb Perspect Biol (2015) 1.00
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
The level of claudin-7 is reduced as an early event in colorectal carcinogenesis. BMC Cancer (2011) 0.96
Diabetic macular edema: new concepts in patho-physiology and treatment. Cell Biosci (2014) 0.95
KLHL3 regulates paracellular chloride transport in the kidney by ubiquitination of claudin-8. Proc Natl Acad Sci U S A (2015) 0.95
Tight junction composition is altered in the epithelium of polycystic kidneys. J Pathol (2008) 0.95
Tight junctions in salivary epithelium. J Biomed Biotechnol (2010) 0.93
Acute oxidative stress affects IL-8 and TNF-α expression in IPEC-J2 porcine epithelial cells. Inflammation (2012) 0.91
Claudins in renal physiology and disease. Pediatr Nephrol (2011) 0.89
Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome. Reprod Biol Endocrinol (2009) 0.89
ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape. PLoS One (2014) 0.88
Rab25 regulates integrin expression in polarized colonic epithelial cells. Mol Biol Cell (2013) 0.87
Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells. Am J Physiol Regul Integr Comp Physiol (2008) 0.87
Claudins and the kidney. J Am Soc Nephrol (2014) 0.87
Scanning ion conductance microscopy measurement of paracellular channel conductance in tight junctions. Anal Chem (2013) 0.86
Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury. Am J Physiol Lung Cell Mol Physiol (2014) 0.86
The tight junction protein claudin-b regulates epithelial permeability and sodium handling in larval zebrafish, Danio rerio. Am J Physiol Regul Integr Comp Physiol (2013) 0.86
Biochemical and biophysical analyses of tight junction permeability made of claudin-16 and claudin-19 dimerization. Mol Biol Cell (2015) 0.84
Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS One (2015) 0.84
Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells. Histochem Cell Biol (2008) 0.84
Freeze-fracture electron microscopic study of tight junction strands in HEK293 cells and MDCK II cells expressing claudin-1 mutants in the second extracellular loop. Histochem Cell Biol (2009) 0.83
Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions. Am J Physiol Cell Physiol (2015) 0.82
Functional characterization and localization of a gill-specific claudin isoform in Atlantic salmon. Am J Physiol Regul Integr Comp Physiol (2011) 0.82
Pulmonary epithelial barrier function: some new players and mechanisms. Am J Physiol Lung Cell Mol Physiol (2015) 0.82
Arsenic compromises conducting airway epithelial barrier properties in primary mouse and immortalized human cell cultures. PLoS One (2013) 0.81
Claudins and renal salt transport. Clin Exp Nephrol (2011) 0.81
Build them up and break them down: Tight junctions of cell lines expressing typical hepatocyte polarity with a varied repertoire of claudins. Tissue Barriers (2013) 0.80
Rab14 regulation of claudin-2 trafficking modulates epithelial permeability and lumen morphogenesis. Mol Biol Cell (2014) 0.80
Formation of aberrant TJ strands by overexpression of claudin-15 in MDCK II cells. Histochem Cell Biol (2007) 0.80
Active and passive involvement of claudins in the pathophysiology of intestinal inflammatory diseases. Pflugers Arch (2016) 0.79
Detection of tight junction barrier function in vivo by biotin. Methods Mol Biol (2011) 0.79
Comparative characterization of mouse rectum CMT93-I and -II cells by expression of claudin isoforms and tight junction morphology and function. Histochem Cell Biol (2007) 0.79
Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1β-TNFα Signaling. PLoS One (2015) 0.79
Tight junction physiology of pleural mesothelium. Front Physiol (2014) 0.78
Transcriptional regulators of claudins in epithelial tight junctions. Mediators Inflamm (2015) 0.78
Trends in drug delivery through tissue barriers containing tight junctions. Tissue Barriers (2013) 0.78
HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation. Am J Pathol (2015) 0.78
Claudin-4 forms a paracellular barrier, revealing the interdependence of claudin expression in the loose epithelial cell culture model opossum kidney cells. Am J Physiol Cell Physiol (2012) 0.78
Chloride secretion by renal collecting ducts. Curr Opin Nephrol Hypertens (2015) 0.77
Necrotizing enterocolitis in a mouse model leads to widespread renal inflammation, acute kidney injury, and disruption of renal tight junction proteins. Pediatr Res (2015) 0.77
Emerging multifunctional roles of Claudin tight junction proteins in bone. Endocrinology (2014) 0.77
Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem (2016) 0.77
Claudins in barrier and transport function-the kidney. Pflugers Arch (2016) 0.76
Tight junctions in pulmonary epithelia during lung inflammation. Pflugers Arch (2016) 0.75
Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Mol Cell Biol (2016) 0.75
Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS One (2017) 0.75
Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation. Ann N Y Acad Sci (2017) 0.75
Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer's Disease. Int J Mol Sci (2017) 0.75
Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets. Sci Rep (2017) 0.75
Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron (2002) 3.81
Beyond the gap: functions of unpaired connexon channels. Nat Rev Mol Cell Biol (2003) 3.75
Electrical synapses in the thalamic reticular nucleus. J Neurosci (2002) 2.47
Gap junctions. Cold Spring Harb Perspect Biol (2009) 2.27
Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex. J Clin Invest (2008) 2.24
Cooperation between snail and LEF-1 transcription factors is essential for TGF-beta1-induced epithelial-mesenchymal transition. Mol Biol Cell (2006) 2.06
Rhythmicity without synchrony in the electrically uncoupled inferior olive. J Neurosci (2002) 1.95
Paracellin-1 and the modulation of ion selectivity of tight junctions. J Cell Sci (2005) 1.90
Connexin37 protects against atherosclerosis by regulating monocyte adhesion. Nat Med (2006) 1.70
Convergence and segregation of the multiple rod pathways in mammalian retina. J Neurosci (2004) 1.69
Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes. J Mol Cell Cardiol (2003) 1.67
Transgenic RNAi depletion of claudin-16 and the renal handling of magnesium. J Biol Chem (2007) 1.64
Paracellular ion channel at the tight junction. Biophys J (2003) 1.63
Connexins are critical for normal myelination in the CNS. J Neurosci (2003) 1.63
Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium. Proc Natl Acad Sci U S A (2009) 1.60
Connexins: functions without junctions. Curr Opin Cell Biol (2004) 1.47
Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems. J Neurosci (2002) 1.45
Central role of connexin40 in the propagation of electrically activated vasodilation in mouse cremasteric arterioles in vivo. Circ Res (2003) 1.45
Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption. Development (2008) 1.44
Genetic dissection of rod and cone pathways in the dark-adapted mouse retina. J Neurophysiol (2009) 1.35
CLDN16 genotype predicts renal decline in familial hypomagnesemia with hypercalciuria and nephrocalcinosis. J Am Soc Nephrol (2007) 1.35
Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Mol Biol Cell (2002) 1.32
Four classes of intercellular channels between glial cells in the CNS. J Neurosci (2004) 1.32
Relative contributions of rod and cone bipolar cell inputs to AII amacrine cell light responses in the mouse retina. J Physiol (2007) 1.30
Morphology and tracer coupling pattern of alpha ganglion cells in the mouse retina. J Comp Neurol (2005) 1.22
The extracellular matrix controls gap junction protein expression and function in postnatal hippocampal neural progenitor cells. BMC Neurosci (2009) 1.18
Genetic and physiological evidence that oligodendrocyte gap junctions contribute to spatial buffering of potassium released during neuronal activity. J Neurosci (2006) 1.18
Unique distributions of the gap junction proteins connexin29, connexin32, and connexin47 in oligodendrocytes. Glia (2004) 1.13
Claudin-16 and claudin-19 function in the thick ascending limb. Curr Opin Nephrol Hypertens (2010) 1.09
Direct rod input to cone BCs and direct cone input to rod BCs challenge the traditional view of mammalian BC circuitry. Proc Natl Acad Sci U S A (2009) 1.08
Connexin36 is required for gap junctional coupling of most ganglion cell subtypes in the mouse retina. J Comp Neurol (2010) 1.03
Lens gap junctional coupling is modulated by connexin identity and the locus of gene expression. Invest Ophthalmol Vis Sci (2004) 1.03
Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct. J Neurosci Res (2008) 1.01
Connexin43 is required for production of the aqueous humor in the murine eye. J Cell Sci (2006) 0.99
Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice. J Neurosci (2006) 0.99
Neuronal coupling via connexin36 contributes to spontaneous synaptic currents of striatal medium-sized spiny neurons. J Neurosci Res (2008) 0.97
Salt and acid-base metabolism in claudin-16 knockdown mice: impact for the pathophysiology of FHHNC patients. Am J Physiol Renal Physiol (2008) 0.95
Functional heterotypic interactions between astrocyte and oligodendrocyte connexins. Glia (2011) 0.94
Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum. Mol Cell Biol (2005) 0.93
Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels. Mol Biol Cell (2011) 0.93
Rod, M-cone and M/S-cone inputs to hyperpolarizing bipolar cells in the mouse retina. J Physiol (2012) 0.92
Deletion of oligodendrocyte Cx32 and astrocyte Cx43 causes white matter vacuolation, astrocyte loss and early mortality. Glia (2011) 0.89
Visual responses in the lateral geniculate evoked by Cx36-independent rod pathways. Vision Res (2010) 0.89
Gap junctions are essential for generating the correlated spike activity of neighboring retinal ganglion cells. PLoS One (2013) 0.87
Oligodendrocyte progenitor enrichment in the connexin32 null-mutant mouse. J Neurosci (2003) 0.86
Depression of intraocular pressure following inactivation of connexin43 in the nonpigmented epithelium of the ciliary body. Invest Ophthalmol Vis Sci (2009) 0.85
Survey on amacrine cells coupling to retrograde-identified ganglion cells in the mouse retina. Invest Ophthalmol Vis Sci (2013) 0.85
Insights into driving forces and paracellular permeability from claudin-16 knockdown mouse. Ann N Y Acad Sci (2009) 0.84
Atrioventricular nodal reverse facilitation in connexin40-deficient mice. Heart Rhythm (2005) 0.81
A novel, highly sensitive method for assessing gap junctional coupling. J Neurosci Methods (2013) 0.79
Multiple connexins contribute to intercellular communication in the Xenopus embryo. J Cell Sci (2003) 0.78
Amphetamine withdrawal produces region-specific and time-dependent changes in connexin36 expression in rat brain. Synapse (2005) 0.78
Global issues in medical education. Lancet (2002) 0.75
Xwnt-2 (Xwnt-2b) is maternally expressed in Xenopus oocytes and embryos. Biochim Biophys Acta (2002) 0.75
Thyroid disease in children: part 1: State-of-the-art imaging in pediatric hypothyroidism. Pediatr Radiol (2013) 0.75