Published in J Mol Biol on September 12, 2006
Crystallizing membrane proteins using lipidic mesophases. Nat Protoc (2009) 6.36
Colicin biology. Microbiol Mol Biol Rev (2007) 5.54
TonB-dependent transporters: regulation, structure, and function. Annu Rev Microbiol (2010) 2.72
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. J R Soc Interface (2009) 2.69
Influence of solubilizing environments on membrane protein structures. Trends Biochem Sci (2010) 1.74
Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes. Biochemistry (2012) 1.57
Overcoming the challenges of membrane protein crystallography. Curr Opin Struct Biol (2008) 1.57
The structural biology of β-barrel membrane proteins: a summary of recent reports. Curr Opin Struct Biol (2011) 1.25
A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes. Acta Crystallogr F Struct Biol Commun (2015) 1.19
Conversion of cobinamide into adenosylcobamide in bacteria and archaea. J Bacteriol (2007) 1.16
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler. Structure (2010) 1.09
Mobility of BtuB and OmpF in the Escherichia coli outer membrane: implications for dynamic formation of a translocon complex. Biophys J (2010) 1.08
LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Cryst Growth Des (2008) 1.08
Crystallizing membrane proteins for structure determination using lipidic mesophases. J Vis Exp (2010) 1.04
Redesign of a plugged beta-barrel membrane protein. J Biol Chem (2010) 1.04
Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes. Proc Natl Acad Sci U S A (2011) 1.00
Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Methods (2011) 0.98
Osmolytes modulate conformational exchange in solvent-exposed regions of membrane proteins. Protein Sci (2010) 0.97
Crystallizing membrane proteins for structure-function studies using lipidic mesophases. Biochem Soc Trans (2011) 0.97
Molecular origin of electron paramagnetic resonance line shapes on β-barrel membrane proteins: the local solvation environment modulates spin-label configuration. Biochemistry (2011) 0.96
Unlocking the eukaryotic membrane protein structural proteome. Curr Opin Struct Biol (2010) 0.95
ArsAB, a novel enzyme from Sporomusa ovata activates phenolic bases for adenosylcobamide biosynthesis. Mol Microbiol (2011) 0.95
Reconstitution of bacterial outer membrane TonB-dependent transporters in planar lipid bilayer membranes. Proc Natl Acad Sci U S A (2009) 0.92
Coupling of calcium and substrate binding through loop alignment in the outer-membrane transporter BtuB. J Mol Biol (2009) 0.88
The genome of Rhodobacter sphaeroides strain 2.4.1 encodes functional cobinamide salvaging systems of archaeal and bacterial origins. Mol Microbiol (2008) 0.87
The effect of calcium on the conformation of cobalamin transporter BtuB. Proteins (2010) 0.87
Structure refinement of the OpcA adhesin using molecular dynamics. Biophys J (2007) 0.86
Membrane thickness varies around the circumference of the transmembrane protein BtuB. Biophys J (2011) 0.82
Renaturing membrane proteins in the lipid cubic phase, a nanoporous membrane mimetic. Sci Rep (2014) 0.81
The N-terminal domain of a TonB-dependent transporter undergoes a reversible stepwise denaturation. Biochemistry (2012) 0.81
Celebrating structural biology. Nat Struct Mol Biol (2011) 0.80
Molecular basis for substrate-dependent transmembrane signaling in an outer-membrane transporter. J Mol Biol (2007) 0.79
The Colicin E1 TolC-Binding Conformer: Pillar or Pore Function of TolC in Colicin Import? Biochemistry (2016) 0.76
Membrane proteins in four acts: function precedes structure determination. Methods (2011) 0.76
Methods for studying interactions of detergents and lipids with α-helical and β-barrel integral membrane proteins. Curr Protoc Protein Sci (2013) 0.76
Allosteric Signaling Is Bidirectional in an Outer-Membrane Transport Protein. Biophys J (2016) 0.75
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers (1983) 99.69
Membrane protein folding and stability: physical principles. Annu Rev Biophys Biomol Struct (1999) 10.13
OPM: orientations of proteins in membranes database. Bioinformatics (2006) 5.87
Lipidic cubic phases: a novel concept for the crystallization of membrane proteins. Proc Natl Acad Sci U S A (1996) 5.79
Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics. Biochemistry (1996) 5.52
Structure of the light-driven chloride pump halorhodopsin at 1.8 A resolution. Science (2000) 3.93
A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases. Acta Crystallogr D Biol Crystallogr (2004) 3.49
A simple mechanical mixer for small viscous lipid-containing samples. Chem Phys Lipids (1998) 2.88
Membrane protein crystallization. J Struct Biol (2003) 2.77
Room to move: crystallizing membrane proteins in swollen lipidic mesophases. J Mol Biol (2006) 2.46
Substrate-induced transmembrane signaling in the cobalamin transporter BtuB. Nat Struct Biol (2003) 2.41
Outer membrane active transport: structure of the BtuB:TonB complex. Science (2006) 2.04
"...the tyranny of the lattice...". Proc Natl Acad Sci U S A (1994) 2.03
Structure of TonB in complex with FhuA, E. coli outer membrane receptor. Science (2006) 2.01
The structure of BtuB with bound colicin E3 R-domain implies a translocon. Nat Struct Biol (2003) 1.96
Membrane protein crystallization in lipidic mesophases with tailored bilayers. Structure (2004) 1.70
X-Ray structure determination of three mutants of the bacterial photosynthetic reaction centers from Rb. sphaeroides; altered proton transfer pathways. Structure (2004) 1.55
The Tol proteins of Escherichia coli and their involvement in the translocation of group A colicins. Biochimie (2002) 1.53
Detergents destabilize the cubic phase of monoolein: implications for membrane protein crystallization. Biophys J (2003) 1.49
Membrane protein dynamics versus environment: simulations of OmpA in a micelle and in a bilayer. J Mol Biol (2003) 1.47
Comparative structural analysis of TonB-dependent outer membrane transporters: implications for the transport cycle. Proteins (2005) 1.36
Substrate-induced conformational changes of the periplasmic N-terminus of an outer-membrane transporter by site-directed spin labeling. Biochemistry (2003) 1.31
Spectroscopic evidence that osmolytes used in crystallization buffers inhibit a conformation change in a membrane protein. Biochemistry (2003) 1.30
Purification and characterization of monomeric Escherichia coli vitamin B12 receptor with high affinity for colicin E3. J Biol Chem (1998) 1.21
Crystallization and initial X-ray diffraction of BtuB, the integral membrane cobalamin transporter of Escherichia coli. Acta Crystallogr D Biol Crystallogr (2003) 1.12
Gramicidin structure and disposition in highly curved membranes. J Struct Biol (2005) 1.12
Biophysical and transfection studies of the diC(14)-amidine/DNA complex. Biophys J (2002) 1.07
Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter. Proc Natl Acad Sci U S A (2003) 1.02
Rational design of lipid molecular structure: a case study involving the C19:1c10 monoacylglycerol. Biophys J (2001) 0.96
A requirement for calcium in the transport of cobalamin across the outer membrane of Escherichia coli. J Biol Chem (1986) 0.93
The temperature-composition phase diagram and mesophase structure characterization of monopentadecenoin in water. Biophys J (1994) 0.90
Controlling release from the lipidic cubic phase. Amino acids, peptides, proteins and nucleic acids. J Control Release (2005) 0.88
Ankylosing spondylitis and HL-A 27. Lancet (1973) 11.99
Highly pathogenic H5N1 influenza virus infection in migratory birds. Science (2005) 9.64
The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Science (1996) 9.32
Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal Biochem (1994) 7.30
7T vs. 4T: RF power, homogeneity, and signal-to-noise comparison in head images. Magn Reson Med (2001) 7.05
Structures of metal sites of oxidized bovine heart cytochrome c oxidase at 2.8 A. Science (1995) 5.43
Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science (1998) 5.01
Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry (2008) 4.14
Reiter's disease and HL-A 27. Lancet (1973) 4.10
Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature (2000) 3.83
Prevalence and genetic diversity of coronaviruses in bats from China. J Virol (2006) 3.37
Phases and phase transitions of the phosphatidylcholines. Biochim Biophys Acta (1998) 3.10
The phase diagram of the monoolein/water system: metastability and equilibrium aspects. Biomaterials (2000) 3.08
Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site. Proc Natl Acad Sci U S A (1989) 2.92
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem (1999) 2.89
A simple mechanical mixer for small viscous lipid-containing samples. Chem Phys Lipids (1998) 2.88
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med (2001) 2.87
Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat Struct Biol (1997) 2.81
Fluorescence quenching in model membranes. 3. Relationship between calcium adenosinetriphosphatase enzyme activity and the affinity of the protein for phosphatidylcholines with different acyl chain characteristics. Biochemistry (1981) 2.77
BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics. Hum Mol Genet (2001) 2.76
Acute anterior uveitis and HL-A 27. Lancet (1973) 2.74
Pharmacodynamics of fluconazole in a murine model of systemic candidiasis. Antimicrob Agents Chemother (1998) 2.59
Tenascin-X deficiency is associated with Ehlers-Danlos syndrome. Nat Genet (1997) 2.56
Cytokinin action is coupled to ethylene in its effects on the inhibition of root and hypocotyl elongation in Arabidopsis thaliana seedlings. Plant Physiol (1995) 2.52
Persistent genetic abnormalities in Barrett's esophagus after photodynamic therapy. Gastroenterology (2000) 2.50
Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol (1993) 2.46
Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience. Neurology (2009) 2.41
Kinetics and mechanism of the lamellar gel/lamellar liquid-crystal and lamellar/inverted hexagonal phase transition in phosphatidylethanolamine: a real-time X-ray diffraction study using synchrotron radiation. Biochemistry (1985) 2.37
Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity. Nat Med (2005) 2.28
Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infection. Antimicrob Agents Chemother (2001) 2.24
Large-scale concatenation cDNA sequencing. Genome Res (1997) 2.18
Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science (1999) 2.14
In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation. Clin Immunol (2005) 2.07
The Membrane Protein Data Bank. Cell Mol Life Sci (2006) 2.07
Outer membrane permeability and beta-lactamase stability of dipolar ionic cephalosporins containing methoxyimino substituents. Antimicrob Agents Chemother (1990) 2.03
Sequence homology and structural similarity between cytochrome b of mitochondrial complex III and the chloroplast b6-f complex: position of the cytochrome b hemes in the membrane. Proc Natl Acad Sci U S A (1984) 2.01
Autosomal dominant moyamoya disease maps to chromosome 17q25.3. Neurology (2008) 2.00
PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers. Oncogene (1998) 1.98
Multiple-locus departures from panmictic equilibrium within and between village gene pools of Amerindian tribes at different stages of agglomeration. Genetics (1983) 1.93
Effect of conjugated linoleic acid on body composition in mice. Lipids (1997) 1.92
Transgenic mouse model for skin malignant melanoma. Oncogene (1998) 1.90
Heterogeneous distribution of the two components of delayed rectifier K+ current: a potential mechanism of the proarrhythmic effects of methanesulfonanilideclass III agents. Cardiovasc Res (1999) 1.89
Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival. FASEB J (2001) 1.86
Pacing-induced heart failure causes a reduction of delayed rectifier potassium currents along with decreases in calcium and transient outward currents in rabbit ventricle. Cardiovasc Res (2000) 1.86
Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice. Proc Natl Acad Sci U S A (1992) 1.84
Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel. Nat Genet (1999) 1.83
A "double adaptor" method for improved shotgun library construction. Anal Biochem (1996) 1.81
Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms. Cancer Res (2001) 1.80
The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer. Cancer Res (2001) 1.80
Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB. RNA (1999) 1.78
Regulation of left-right asymmetry by thresholds of Pitx2c activity. Development (2001) 1.77
Crystallization screens: compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins. Biophys J (2001) 1.74
Prevalence of helminths in water buffaloes in Hunan Province, China. Trop Anim Health Prod (2008) 1.72
Visualization and mechanical manipulations of individual fibrin fibers suggest that fiber cross section has fractal dimension 1.3. Biophys J (2004) 1.71
Impact of drug-exposure intensity and duration of therapy on the emergence of Staphylococcus aureus resistance to a quinolone antimicrobial. J Infect Dis (2007) 1.70
Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation. J Biol Chem (2000) 1.70
The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences. Neuroscience (2003) 1.69
Platelet-derived endothelial cell growth factor in human colon cancer angiogenesis: role of infiltrating cells. J Natl Cancer Inst (1996) 1.69
Studies on the depolarization of the Escherichia coli cell membrane by colicin E1. J Biol Chem (1977) 1.68
HL-A 27 and arthropathies associated with ulcerative colitis and psoriasis. Lancet (1974) 1.68
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. J Biol Chem (1999) 1.68
Terahertz response and colossal Kerr rotation from the surface states of the topological insulator Bi2Se3. Phys Rev Lett (2012) 1.67
Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory. Mol Psychiatry (2010) 1.66
Widespread alterations of alpha-synuclein in multiple system atrophy. Am J Pathol (1999) 1.65
Expression of epidermal growth factor receptor and human papillomavirus E6/E7 proteins in cervical carcinoma cells. J Natl Cancer Inst (1997) 1.63
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading. J Cell Biol (2000) 1.63
Montelukast improves regional air-trapping due to small airways obstruction in asthma. Eur Respir J (2006) 1.61
The neuronal ceroid lipofuscinoses in human EPMR and mnd mutant mice are associated with mutations in CLN8. Nat Genet (1999) 1.61
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain. J Biol Chem (1997) 1.61
Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line. J Clin Invest (1985) 1.61
Aldosterone responsiveness of A6 cells is restored by cloned rat mineralocorticoid receptor. Am J Physiol (1998) 1.60
Pho signal transduction network reveals direct transcriptional regulation of one two-component system by another two-component regulator: Bacillus subtilis PhoP directly regulates production of ResD. Mol Microbiol (1998) 1.60
Ferredoxin:NADP+ oxidoreductase is a subunit of the chloroplast cytochrome b6f complex. J Biol Chem (2001) 1.59
Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases. Cancer (2000) 1.58
Membrane protein crystallization in lipidic mesophases: detergent effects. Biophys J (2000) 1.56
Cysteine substitutions in epidermal growth factor-like domains of fibrillin-1: distinct effects on biochemical and clinical phenotypes. Am J Hum Genet (1999) 1.56
Molecular mechanism for the crystallization of bacteriorhodopsin in lipidic cubic phases. FEBS Lett (2001) 1.55
Markedly elevated levels of vascular endothelial growth factor in malignant ascites. Ann Surg Oncol (1999) 1.54
Silent mutation induces exon skipping of fibrillin-1 gene in Marfan syndrome. Nat Genet (1997) 1.53
Cloning and functional expression of a cDNA encoding a pheromone gland-specific acyl-CoA Delta11-desaturase of the cabbage looper moth, Trichoplusia ni. Proc Natl Acad Sci U S A (1998) 1.52
Urethral seam formation and hypospadias. Cell Tissue Res (2001) 1.50
Marfan Database (third edition): new mutations and new routines for the software. Nucleic Acids Res (1998) 1.49
Detergents destabilize the cubic phase of monoolein: implications for membrane protein crystallization. Biophys J (2003) 1.49
The membrane channel-forming bacteriocidal protein, colicin El. Biochim Biophys Acta (1983) 1.49
Retinal prosthesis: an encouraging first decade with major challenges ahead. Ophthalmology (2001) 1.48
Structural similarities of the staphylococcin-like peptide Pep-5 to the peptide antibiotic nisin. Antimicrob Agents Chemother (1985) 1.48
Induction of nitric oxide synthase activity in human astrocytes by interleukin-1 beta and interferon-gamma. J Neuroimmunol (1993) 1.48
A comparison of the mechanical and structural properties of fibrin fibers with other protein fibers. Cell Biochem Biophys (2007) 1.48
Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance. Am J Transplant (2009) 1.48
Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors. Br J Cancer (2001) 1.47
Crystal structure of chloroplast cytochrome f reveals a novel cytochrome fold and unexpected heme ligation. Structure (1994) 1.47
Effects of combination anti-vascular endothelial growth factor receptor and anti-epidermal growth factor receptor therapies on the growth of gastric cancer in a nude mouse model. Eur J Cancer (2002) 1.47
Mechanism of action of Escherichia coli heat stable enterotoxin in a human colonic cell line. J Clin Invest (1988) 1.47
Evidence for an increase in microviscosity of plasma membranes from soybean hypocotyls induced by the plant hormone, indole-3-acetic Acid. Plant Physiol (1976) 1.47
Inhibition of neutrophil activation by ranitidine contributes to prevent stress-induced gastric mucosal injury in rats. Crit Care Med (2000) 1.46
Review of global regulations concerning biowaivers for immediate release solid oral dosage forms. Eur J Pharm Sci (2006) 1.46
Studies on the mechanism of action of channel-forming colicins using artificial membranes. J Membr Biol (1984) 1.45
Epigenetic interactions and the structure of phenotypic variation in the cranium. Evol Dev (2007) 1.45
Emerging HIV infections with distinct subtypes of HIV-1 infection among injection drug users from geographically separate locations in Guangxi Province, China. J Acquir Immune Defic Syndr (1999) 1.45