Published in Mol Pharmacol on October 06, 2006
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Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals. Nucleic Acids Res (2006) 1.98
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Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells. Nucleic Acids Res (2007) 1.23
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Parental beliefs and worries regarding adolescent chronic pain. Clin J Pain (2009) 1.05
Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site. Angew Chem Int Ed Engl (2004) 1.04
Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease. J Neurosci Res (2006) 1.04
Pharmacologic management of acute pediatric pain. Anesthesiol Clin (2009) 1.03
Human Dicer binds short single-strand and double-strand RNA with high affinity and interacts with different regions of the nucleic acids. J Biol Chem (2008) 1.02
Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate. J Biol Chem (2003) 1.02
Adolescent self-perception: associations with chronic musculoskeletal pain and functional disability. J Pain (2007) 0.99
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The positional influence of the helical geometry of the heteroduplex substrate on human RNase H1 catalysis. Mol Pharmacol (2006) 0.94
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice. Nucleic Acids Res (2010) 0.93
Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: a synergistic hydrophobic effect against resistant bacteria. Bioorg Med Chem Lett (2010) 0.93
Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animals. ACS Chem Biol (2013) 0.93
Adolescent-parent relationships in the context of adolescent chronic pain conditions. Clin J Pain (2006) 0.92
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A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing the Nuss procedure. Anesth Analg (2006) 0.90
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid. J Med Chem (2005) 0.90
Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids. J Med Chem (2006) 0.89
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An evaluation of the efficacy and tolerability of oral tramadol hydrochloride tablets for the treatment of postsurgical pain in children. Anesth Analg (2002) 0.86
Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycin. J Med Chem (2007) 0.86
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Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue. J Med Chem (2010) 0.86
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Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. PLoS One (2013) 0.84
Pain beliefs and readiness to change among adolescents with chronic musculoskeletal pain and their parents before an initial pain clinic evaluation. Clin J Pain (2014) 0.83
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Treatment expectations among adolescents with chronic musculoskeletal pain and their parents before an initial pain clinic evaluation. Clin J Pain (2014) 0.82
RNA helicase A is not required for RISC activity. Biochim Biophys Acta (2013) 0.81
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Gender differences in post-operative pain and patient controlled analgesia use among adolescent surgical patients. Pain (2004) 0.80
siRNAs targeted to certain polyadenylation sites promote specific, RISC-independent degradation of messenger RNAs. Nucleic Acids Res (2012) 0.79
Protracted pain following partial splenic embolization in an adolescent female with hypersplenism. Paediatr Anaesth (2005) 0.78
The synthesis and 16S A-site rRNA recognition of carbohydrate-free aminoglycosides. Bioorg Med Chem Lett (2005) 0.76
Health security preparedness and industry trends. Health Secur (2015) 0.75
Alternative syntheses of (S)-cEt-BNA: a key constrained nucleoside component of bioactive antisense gapmer sequences. J Org Chem (2014) 0.75
Synthesis of DNA using a new two-step cycle. Methods Mol Biol (2005) 0.75
Does the use of fentanyl in epidural solutions for postthoracotomy pain management in neonates affect surgical outcome? J Pediatr Surg (2005) 0.75
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Efficient and selective knockdown of small non-coding RNAs. Methods Mol Biol (2015) 0.75
Poster 466 Inpatient Pain Rehabilitation Outcomes for Adolescents with Chronic Pain and Pain-Associated Disability Secondary to Sickle Cell Disease. PM R (2016) 0.75