Published in Crit Care on January 01, 2006
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Activated protein C in sepsis: the promise of nonanticoagulant activated protein C. Curr Opin Hematol (2008) 0.86
Drotrecogin alfa (activated) in patients with severe sepsis and a high risk of death. Crit Care (2006) 0.76
Measuring inconsistency in meta-analyses. BMJ (2003) 128.20
Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med (2001) 27.70
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med (2005) 8.55
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med (2003) 3.18
Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis? Crit Care (2006) 1.61
Prescription of rh-APC differs substantially among western European countries. Intensive Care Med (2006) 0.98
Activated protein C in sepsis: down but not out, yet. Crit Care (2006) 0.88
Drotrecogin alfa (activated) administration: too many subgroups. Crit Care Med (2003) 0.84
Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA (2005) 23.44
Randomized trials stopped early for benefit: a systematic review. JAMA (2005) 8.43
A guide for the design and conduct of self-administered surveys of clinicians. CMAJ (2008) 6.72
High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med (2015) 6.06
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90
Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study. Crit Care Med (2014) 5.07
Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med (2008) 5.06
Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis. Crit Care Med (2014) 4.11
Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med (2007) 3.45
The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study*. Crit Care Med (2014) 3.29
A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial. JAMA (2011) 3.08
Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med (2006) 3.06
Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis. Ann Intern Med (2015) 2.95
A Systematic Review of Surgical Randomized Controlled Trials: Part I. Risk of Bias and Outcomes: Common Pitfalls Plastic Surgeons Can Overcome. Plast Reconstr Surg (2016) 2.89
Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med (2010) 2.88
Medical admission order sets to improve deep vein thrombosis prophylaxis rates and other outcomes. J Hosp Med (2009) 2.49
Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ (2007) 2.44
Use of non-invasive ventilation to wean critically ill adults off invasive ventilation: meta-analysis and systematic review. BMJ (2009) 2.44
The design and interpretation of pilot trials in clinical research in critical care. Crit Care Med (2009) 2.38
Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ (2007) 2.33
Mortality predictions in the intensive care unit: comparing physicians with scoring systems. Crit Care Med (2006) 2.29
Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest (2013) 2.24
Systematic reviewers neglect bias that results from trials stopped early for benefit. J Clin Epidemiol (2007) 2.20
Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*. Crit Care Med (2015) 2.16
Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials. Am J Respir Crit Care Med (2012) 2.15
High values of the pulmonary artery wedge pressure in patients with acute lung injury and acute respiratory distress syndrome. Intensive Care Med (2002) 2.15
Prophylactic magnesium for improving neurologic outcome after aneurysmal subarachnoid hemorrhage: systematic review and meta-analysis. J Crit Care (2012) 2.08
Recruitment maneuvers for acute lung injury: a systematic review. Am J Respir Crit Care Med (2008) 1.91
Sex-and age-based differences in the delivery and outcomes of critical care. CMAJ (2007) 1.91
Bilevel noninvasive positive pressure ventilation for acute respiratory failure: survey of Ontario practice. Crit Care Med (2005) 1.85
Noninvasive ventilation as a weaning strategy for mechanical ventilation in adults with respiratory failure: a Cochrane systematic review. CMAJ (2013) 1.82
Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis. Crit Care Med (2010) 1.78
High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis. Crit Care Med (2010) 1.77
Quality of professional society guidelines and consensus conference statements in critical care. Crit Care Med (2008) 1.74
Determination of neurologic prognosis and clinical decision making in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons, and neurologists. Crit Care Med (2013) 1.72
Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study. CMAJ (2011) 1.72
Pulmonary artery catheters: evolving rates and reasons for use. Crit Care Med (2011) 1.70
Noninvasive ventilation for acute respiratory failure near the end of life. Crit Care Med (2008) 1.65
Access to urban acute care services in high- vs. middle-income countries: an analysis of seven cities. Intensive Care Med (2013) 1.64
Enrollment of intensive care unit patients into clinical studies: a trinational survey of researchers' experiences, beliefs, and practices. Crit Care Med (2008) 1.63
A meta-analysis of noninvasive weaning to facilitate liberation from mechanical ventilation. Can J Anaesth (2006) 1.62
Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis? Crit Care (2006) 1.61
Abstract reporting in randomized clinical trials of acute lung injury: an audit and assessment of a quality of reporting score. Crit Care Med (2005) 1.61
The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: a randomized double-blind placebo controlled clinical trial. Intensive Care Med (2009) 1.61
Transfusion triggers for guiding RBC transfusion for cardiovascular surgery: a systematic review and meta-analysis*. Crit Care Med (2014) 1.61
Pay for performance in the intensive care unit--opportunity or threat? Crit Care Med (2009) 1.55
High-frequency oscillation in adults: a utilization review. Crit Care Med (2011) 1.55
Knowledge translation interventions for critically ill patients: a systematic review*. Crit Care Med (2013) 1.53
Quality of reporting of surveys in critical care journals: a methodologic review. Crit Care Med (2012) 1.53
Reliability of electrocardiogram interpretation in critically ill patients. Crit Care Med (2006) 1.51
Discordance between perception and treatment practices associated with intensive care unit-acquired bacteriuria and funguria: a Canadian physician survey. Crit Care Med (2008) 1.48
Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data. BMC Med Res Methodol (2007) 1.47
Thrombocytopenia in medical-surgical critically ill patients: prevalence, incidence, and risk factors. J Crit Care (2005) 1.46
The ratio of means method as an alternative to mean differences for analyzing continuous outcome variables in meta-analysis: a simulation study. BMC Med Res Methodol (2008) 1.46
Nonbeneficial treatment Canada: definitions, causes, and potential solutions from the perspective of healthcare practitioners*. Crit Care Med (2015) 1.45
Coenrollment in a randomized trial of high-frequency oscillation: prevalence, patterns, predictors, and outcomes*. Crit Care Med (2015) 1.41
Outcomes of interfacility critical care adult patient transport: a systematic review. Crit Care (2006) 1.40
The use of wireless e-mail to improve healthcare team communication. J Am Med Inform Assoc (2009) 1.39
Meta-analysis of randomized trials on first line and adjunctive levetiracetam. Can J Neurol Sci (2011) 1.38
Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials. Crit Care (2013) 1.36
An official American Thoracic Society systematic review: the association between health insurance status and access, care delivery, and outcomes for patients who are critically ill. Am J Respir Crit Care Med (2010) 1.32
Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis. Crit Care (2012) 1.28
Clinical review: critical care in the global context--disparities in burden of illness, access, and economics. Crit Care (2008) 1.26
Complications from recruitment maneuvers in patients with acute lung injury: secondary analysis from the lung open ventilation study. Respir Care (2012) 1.16
The effect of telemedicine in critically ill patients: systematic review and meta-analysis. Crit Care (2012) 1.15
Risk of chronic dialysis and death following acute kidney injury. Am J Med (2012) 1.12
Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11
Routine chest x-rays in intensive care units: a systematic review and meta-analysis. Crit Care (2012) 1.11
Pharmacologic treatments for acute respiratory distress syndrome and acute lung injury: systematic review and meta-analysis. Treat Respir Med (2004) 1.11
A Systematic Review of Surgical Randomized Controlled Trials: Part 2. Funding Source, Conflict of Interest, and Sample Size in Plastic Surgery. Plast Reconstr Surg (2016) 1.08
Deep venous thrombosis: clinically silent in the intensive care unit. J Crit Care (2005) 1.08