Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes.

PubWeight™: 2.24‹?› | Rank: Top 2%

🔗 View Article (PMID 23788287)

Published in Chest on October 01, 2013

Authors

David R Williamson, Martin Albert, Diane Heels-Ansdell, Donald M Arnold, François Lauzier, Ryan Zarychanski, Mark Crowther, Theodore E Warkentin, Peter Dodek, John Cade, Olivier Lesur, Wendy Lim, Robert Fowler, Francois Lamontagne, Stephan Langevin, Andreas Freitag, John Muscedere, Jan O Friedrich, William Geerts, Lisa Burry, Jamal Alhashemi, Deborah Cook, PROTECT collaborators, Canadian Critical Care Trials Group, Australian and New Zealand Intensive Care Society Clinical Trials Group

Associated clinical trials:

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT) | NCT00182143

Articles citing this

Platelet Counts, Acute Kidney Injury, and Mortality after Coronary Artery Bypass Grafting Surgery. Anesthesiology (2016) 1.51

Repeated early hemofiltration filters clotting and heparin-induced thrombocytopenia in ICU. J Clin Monit Comput (2014) 1.36

Thrombocytopenia and thromboprophylaxis: a difficult combination? Chest (2013) 1.07

Severe Fever with Thrombocytopenia Syndrome in South Korea, 2013-2015. PLoS Negl Trop Dis (2016) 0.82

Platelet transfusions in cancer patients with hypoproliferative thrombocytopenia in the intensive care unit. Ann Intensive Care (2015) 0.79

Assessment of Haemostasis in Disseminated Intravascular Coagulation by Use of Point-of-Care Assays and Routine Coagulation Tests, in Critically Ill Patients; A Prospective Observational Study. PLoS One (2016) 0.78

The incidence and clinical characteristics by gender differences in patients with Kikuchi-Fujimoto disease. Medicine (Baltimore) (2017) 0.75

Deinagkistrodon acutus envenomation: a report of three cases. J Venom Anim Toxins Incl Trop Dis (2017) 0.75

Severe Thrombocytopenia after Zika Virus Infection, Guadeloupe, 2016. Emerg Infect Dis (2017) 0.75

Risk factors for and prediction of mortality in critically ill medical-surgical patients receiving heparin thromboprophylaxis. Ann Intensive Care (2016) 0.75

Safety and economic considerations of argatroban use in critically ill patients: a retrospective analysis. J Cardiothorac Surg (2015) 0.75

Response. Chest (2013) 0.75

The Incidence, Clinical Outcomes, and Risk Factors of Thrombocytopenia in Intra-Abdominal Infection Patients: A Retrospective Cohort Study. PLoS One (2016) 0.75

Cytopenias among ART-naive patients with advanced HIV disease on enrolment to care and treatment services at a tertiary hospital in Tanzania: A cross-sectional study. Malawi Med J (2017) 0.75

Articles by these authors

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med (2003) 28.68

Intensive versus conventional glucose control in critically ill patients. N Engl J Med (2009) 26.30

Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA (2009) 13.00

Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med (2005) 12.46

Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Engl J Med (2012) 11.83

One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med (2003) 11.77

Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med (2011) 11.69

Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 10.75

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med (2003) 10.39

Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med (2011) 9.96

A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med (2013) 8.94

Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med (2003) 8.55

Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest (2008) 7.94

Screening for Occult Cancer in Unprovoked Venous Thromboembolism. N Engl J Med (2015) 7.39

Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit. N Engl J Med (2003) 7.32

Transfusion strategies for patients in pediatric intensive care units. N Engl J Med (2007) 7.21

Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood (2008) 7.06

Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial. JAMA (2012) 6.69

A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome. N Engl J Med (2003) 6.57

High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56

The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood (2011) 6.50

Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomized trial. JAMA (2013) 6.25

Hypoglycemia and risk of death in critically ill patients. N Engl J Med (2012) 6.17

Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med (2006) 6.15

Aspirin in patients undergoing noncardiac surgery. N Engl J Med (2014) 6.10

Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med (2008) 6.00

Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr (2003) 5.90

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90

Perioperative fluid therapy with tetrastarch and gelatin in cardiac surgery--a prospective sequential analysis*. Crit Care Med (2013) 5.88

Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.88

Systematic overview of warfarin and its drug and food interactions. Arch Intern Med (2005) 5.86

A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med (2006) 5.74

What matters most in end-of-life care: perceptions of seriously ill patients and their family members. CMAJ (2006) 5.70

Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.57

A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. N Engl J Med (2015) 5.28

Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study. Crit Care Med (2014) 5.07

Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med (2008) 5.06

Prevention of VTE in nonsurgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.02

Variation in critical care services across North America and Western Europe. Crit Care Med (2008) 5.00

Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 4.82

Clinical presentation of patients with Ebola virus disease in Conakry, Guinea. N Engl J Med (2014) 4.79

Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA (2010) 4.64

Dalteparin versus unfractionated heparin in critically ill patients. N Engl J Med (2011) 4.59

Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA (2012) 4.58

Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest (2009) 4.51

Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med (2007) 4.42

Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2009) 4.41

Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis. Crit Care Med (2010) 4.39

Toothbrushing for critically ill mechanically ventilated patients: a systematic review and meta-analysis of randomized trials evaluating ventilator-associated pneumonia. Crit Care Med (2013) 4.29

Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis. Crit Care Med (2014) 4.11

Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96

Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res (2006) 3.81

Failure to engage hospitalized elderly patients and their families in advance care planning. JAMA Intern Med (2013) 3.77

Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates. Circulation (2012) 3.74

Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis. Circulation (2008) 3.63

Clinical consequences of red cell storage in the critically ill. Transfusion (2006) 3.57

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. N Engl J Med (2015) 3.57

Publication bias in editorial decision making. JAMA (2002) 3.52

The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med (2010) 3.47

Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial. Ann Intern Med (2013) 3.40

Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients. Ann Intern Med (2007) 3.33

The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study*. Crit Care Med (2014) 3.29

Methodology for the development of antithrombotic therapy and prevention of thrombosis guidelines: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 3.14

Acute kidney injury after cardiac surgery: focus on modifiable risk factors. Circulation (2009) 3.10

Impact of emergency colectomy on survival of patients with fulminant Clostridium difficile colitis during an epidemic caused by a hypervirulent strain. Ann Surg (2007) 3.08

Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ (2007) 3.06

Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med (2006) 3.06

Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. JAMA (2016) 3.06

Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura. Ann Intern Med (2007) 2.97

Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. Am J Respir Crit Care Med (2014) 2.90

Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med (2010) 2.88

The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis. Crit Care Med (2015) 2.85

Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 2.83

Fluids after cardiac surgery: a pilot study of the use of colloids versus crystalloids. Crit Care Med (2010) 2.82