Published in J Biol Chem on October 16, 2006
Nuclear export of proteins and drug resistance in cancer. Biochem Pharmacol (2011) 2.43
Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer. Cancer Res (2010) 2.42
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med (2011) 1.74
A conserved G₁ regulatory circuit promotes asynchronous behavior of nuclei sharing a common cytoplasm. Cell Cycle (2010) 1.63
Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein. PLoS Pathog (2007) 1.29
The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes Dev (2013) 1.28
Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer. Annu Rev Pathol (2009) 1.20
Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation. J Cell Sci (2010) 1.18
Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver. Cell Metab (2016) 1.17
The chemokine CXCL12 promotes survival of postmitotic neurons by regulating Rb protein. Cell Death Differ (2008) 1.16
Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function. PLoS One (2010) 0.99
Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. Oncotarget (2016) 0.98
Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation. Genes Dev (2015) 0.98
Evidence for a mitochondrial localization of the retinoblastoma protein. BMC Cell Biol (2009) 0.95
AKT1 mediates bypass of the G1/S checkpoint after genotoxic stress in normal human cells. Cell Cycle (2009) 0.95
CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo. J Cancer (2013) 0.94
RB regulates pancreas development by stabilizing Pdx1. EMBO J (2011) 0.93
Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells. PLoS One (2012) 0.91
Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle. J Cell Biol (2008) 0.87
RB116: an RB1+ retinoblastoma cell line expressing primitive markers. Mol Vis (2012) 0.77
Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma. Skelet Muscle (2013) 0.77
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Mol Cell (2016) 0.77
Structural Basis of Targeting the Exportin CRM1 in Cancer. Cells (2015) 0.77
Protein mislocalization: mechanisms, functions and clinical applications in cancer. Biochim Biophys Acta (2014) 0.76
SENP1-modulated sumoylation regulates retinoblastoma protein (RB) and Lamin A/C interaction and stabilization. Oncogene (2016) 0.76
Ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein regulates neuroblastoma cell proliferation through p21. Mol Cells (2014) 0.76
Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun (2016) 0.75
Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene (2016) 0.75
Evolution of malignant plasmacytoma cell lines from K14E7 Fancd2-/- mouse long-term bone marrow cultures. Oncotarget (2016) 0.75
Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. Cell Metab (2011) 2.73
De novo formation of a subnuclear body. Science (2008) 2.66
Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice. Oncogene (2003) 2.64
Nucleation of nuclear bodies by RNA. Nat Cell Biol (2011) 2.34
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication. Nat Med (2004) 1.97
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
The moving parts of the nucleolus. Histochem Cell Biol (2005) 1.81
The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol (2006) 1.52
Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function. J Biol Chem (2009) 1.49
Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis. Cancer Res (2005) 1.46
Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem (2002) 1.45
Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator. J Virol (2004) 1.34
Cdk4 promotes adipogenesis through PPARgamma activation. Cell Metab (2005) 1.31
Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs. Mol Cell (2002) 1.30
JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress. EMBO J (2011) 1.28
Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J Biol Chem (2013) 1.25
Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol (2006) 1.25
FBPs are calibrated molecular tools to adjust gene expression. Mol Cell Biol (2006) 1.21
Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells. Nat Commun (2012) 1.18
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol (2008) 1.10
Transforming growth factor-beta pathway: role in pancreas development and pancreatic disease. Cytokine Growth Factor Rev (2005) 1.06
Histone H2A C-terminus regulates chromatin dynamics, remodeling, and histone H1 binding. PLoS Genet (2010) 1.04
Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D. Epigenetics Chromatin (2010) 1.03
SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles. Mol Biol Cell (2012) 0.97
A dual role of linker histone H1.4 Lys 34 acetylation in transcriptional activation. Genes Dev (2012) 0.97
Human T-cell leukemia virus type I p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit. J Biol Chem (2006) 0.95
Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B. J Cell Sci (2011) 0.93
RB regulates pancreas development by stabilizing Pdx1. EMBO J (2011) 0.93
TGF-β/Smad3 Signaling Regulates Brown Adipocyte Induction in White Adipose Tissue. Front Endocrinol (Lausanne) (2012) 0.92
Nonphosphorylated human La antigen interacts with nucleolin at nucleolar sites involved in rRNA biogenesis. Mol Cell Biol (2004) 0.92
Dendritic cell-based vaccines: barriers and opportunities. Future Oncol (2012) 0.91
The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors. Development (2011) 0.90
Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass. PLoS One (2010) 0.90
Conserved zinc fingers mediate multiple functions of ZFP100, a U7snRNP associated protein. RNA (2006) 0.89
Radiation as immunomodulator: implications for dendritic cell-based immunotherapy. Radiat Res (2014) 0.87
PA28γ is a novel corepressor of HTLV-1 replication and controls viral latency. Blood (2012) 0.84
Synchronous bone marrow metastasis from primary splenic angiosarcoma. Am Surg (2010) 0.84
The punctate localization of rat Eag1 K+ channels is conferred by the proximal post-CNBHD region. BMC Neurosci (2014) 0.82
E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation. Cancer Res (2005) 0.81
Mechanisms associated with IL-6-induced up-regulation of Jak3 and its role in monocytic differentiation. Blood (2004) 0.81
Transforming growth factor-β3 (TGF-β3) knock-in ameliorates inflammation due to TGF-β1 deficiency while promoting glucose tolerance. J Biol Chem (2013) 0.81
Type I-polarized BRAF-pulsed dendritic cells induce antigen-specific CD8+ T cells that impact BRAF-mutant murine melanoma. Melanoma Res (2016) 0.78
SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise. J Biol Chem (2015) 0.77
International students in United States' medical schools: does the medical community know they exist? Med Educ Online (2012) 0.75
Profound hyperacute cardiac allograft rejection rescue with biventricular mechanical circulatory support and plasmapheresis, intravenous immunoglobulin, and rituximab therapy. J Cardiothorac Surg (2013) 0.75
Prognosis of patients with melanoma and microsatellitosis undergoing sentinel lymph node biopsy. Ann Surg Oncol (2013) 0.75
From beagles to the bedside: Jonathan Rhoads and parenteral nutrition. South Med J (2012) 0.75
Comparing International and United States Undergraduate Medical Education and Surgical Outcomes Using a Refined Balance Matching Methodology. Ann Surg (2017) 0.75
Complications of alloderm and dermamatrix for parotidectomy reconstruction. Head Neck (2011) 0.75
Racial disparities in the use of outpatient mastectomy. J Surg Res (2013) 0.75
Multimodality treatment considerations in esophageal and gastric cancer: Are we making progress? Bull Am Coll Surg (2015) 0.75
Outcomes of 157 V-Patch(TM) Implants in the Repair of Umbilical, Epigastric, and Incisional Hernias. Am Surg (2016) 0.75