Published in Epigenetics Chromatin on March 24, 2010
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Mol Cell (2012) 1.79
Breaking the histone code with quantitative mass spectrometry. Expert Rev Proteomics (2011) 1.39
H1 histones: current perspectives and challenges. Nucleic Acids Res (2013) 1.35
Quantitative proteomic analysis of histone modifications. Chem Rev (2015) 1.32
SET for life: biochemical activities and biological functions of SET domain-containing proteins. Trends Biochem Sci (2013) 1.22
Histone modifiers in cancer: friends or foes? Genes Cancer (2011) 1.10
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. J Am Chem Soc (2012) 1.09
Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One (2012) 1.06
Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. J Am Chem Soc (2012) 1.02
Basic concepts of epigenetics: impact of environmental signals on gene expression. Epigenetics (2012) 1.02
Mass spectrometry-based proteomics for the analysis of chromatin structure and dynamics. Int J Mol Sci (2013) 0.97
Mapping of six somatic linker histone H1 variants in human breast cancer cells uncovers specific features of H1.2. Nucleic Acids Res (2014) 0.93
Novel roles of Caenorhabditis elegans heterochromatin protein HP1 and linker histone in the regulation of innate immune gene expression. Mol Cell Biol (2011) 0.91
Emerging roles of lysine methylation on non-histone proteins. Cell Mol Life Sci (2015) 0.87
Genome distribution of replication-independent histone H1 variants shows H1.0 associated with nucleolar domains and H1X associated with RNA polymerase II-enriched regions. J Biol Chem (2015) 0.83
Anthrax SET protein: a potential virulence determinant that epigenetically represses NF-κB activation in infected macrophages. J Biol Chem (2013) 0.83
Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4. Epigenetics Chromatin (2013) 0.83
Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2. Antioxid Redox Signal (2014) 0.82
The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle. EMBO Rep (2015) 0.82
Human EHMT2/G9a activates p53 through methylation-independent mechanism. Oncogene (2016) 0.79
Substrate Specificity Profiling of Histone-Modifying Enzymes by Peptide Microarray. Methods Enzymol (2016) 0.78
EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos. Genome Res (2015) 0.77
A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. J Biol Chem (2015) 0.76
Genetically encoded molecular biosensors to image histone methylation in living animals. Anal Chem (2014) 0.76
Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. J Med Chem (2017) 0.75
The Lysine Methyltransferase G9a in Immune Cell Differentiation and Function. Front Immunol (2017) 0.75
Post-translational modifications of the intrinsically disordered terminal domains of histone H1: effects on secondary structure and chromatin dynamics. Chromosoma (2016) 0.75
Chromatin modifications and their function. Cell (2007) 55.98
Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell (2003) 11.33
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev (2002) 10.54
A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science (2002) 7.33
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J Biol Chem (2001) 7.21
Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation. Cell (2005) 6.17
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev (2005) 5.50
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol Cell (2004) 5.06
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc Natl Acad Sci U S A (2005) 4.57
Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem (2006) 3.84
Protein lysine methyltransferase G9a acts on non-histone targets. Nat Chem Biol (2008) 3.53
The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules. Nat Struct Mol Biol (2008) 3.20
In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases. J Biol Chem (2004) 2.86
Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. Mol Cell Biol (1989) 2.75
Histone H1 and its isoforms: contribution to chromatin structure and function. Gene (2008) 2.32
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell (2009) 2.27
Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase. J Biol Chem (2004) 2.09
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding. J Biol Chem (2005) 2.05
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. J Biol Chem (2009) 2.02
The histone H1 family: specific members, specific functions? Biol Chem (2008) 1.91
Mass spectrometric mapping of linker histone H1 variants reveals multiple acetylations, methylations, and phosphorylation as well as differences between cell culture and tissue. Mol Cell Proteomics (2006) 1.90
Chromatin condensation: does histone H1 dephosphorylation play a role? Trends Biochem Sci (1992) 1.85
H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain. J Biol Chem (2005) 1.59
Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype. Mol Cell Biol (2001) 1.52
Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth. PLoS Genet (2008) 1.45
Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. J Proteome Res (2004) 1.33
Histone H1 and the dynamic regulation of chromatin function. Biochem Cell Biol (2003) 1.33
Methods and tips for the purification of human histone methyltransferases. Methods (2003) 1.31
Histone H1 phosphorylation occurs site-specifically during interphase and mitosis: identification of a novel phosphorylation site on histone H1. J Biol Chem (2005) 1.22
Differential affinity of mammalian histone H1 somatic subtypes for DNA and chromatin. BMC Biol (2007) 1.18
Cracking the enigmatic linker histone code. J Biochem (2008) 1.01
Characterisation of human histone H1x. Biol Chem (2005) 0.97
Varied expression patterns of human H1 histone genes in different cell lines. DNA Cell Biol (1997) 0.97
The distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin: distribution in human fetal fibroblasts. Chromosome Res (2000) 0.95
Active genes are tri-methylated at K4 of histone H3. Nature (2002) 15.68
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med (2012) 11.14
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature (2005) 8.53
Methylation of histone H3 Lys 4 in coding regions of active genes. Proc Natl Acad Sci U S A (2002) 7.67
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet (2012) 5.28
Histone deimination antagonizes arginine methylation. Cell (2004) 5.19
Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes. J Biol Chem (2005) 4.78
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol (2007) 3.89
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med (2011) 3.82
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol (2006) 3.65
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol (2011) 3.60
Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. Mol Cell (2003) 3.47
Histone methylation: dynamic or static? Cell (2002) 3.12
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09
Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature (2012) 2.96
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development (2003) 2.91
Methylation at arginine 17 of histone H3 is linked to gene activation. EMBO Rep (2001) 2.83
Asymmetrically modified nucleosomes. Cell (2012) 2.79
Effects of a randomized controlled trial of transcendental meditation on components of the metabolic syndrome in subjects with coronary heart disease. Arch Intern Med (2006) 2.73
De novo formation of a subnuclear body. Science (2008) 2.66
High throughput characterization of combinatorial histone codes. Mol Cell Proteomics (2009) 2.52
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature (2010) 2.49
Carbon isotope constraints on the deglacial CO₂ rise from ice cores. Science (2012) 2.41
Nucleation of nuclear bodies by RNA. Nat Cell Biol (2011) 2.34
In vivo residue-specific histone methylation dynamics. J Biol Chem (2009) 2.33
Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Res (2004) 2.28
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell (2011) 2.27
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell (2009) 2.27
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature (2010) 2.20
One-pot shotgun quantitative mass spectrometry characterization of histones. J Proteome Res (2009) 2.13
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol (2010) 2.07
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding. J Biol Chem (2005) 2.05
Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster. Mol Cell Biol (2008) 2.01
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication. Nat Med (2004) 1.97
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Mol Cell (2011) 1.96
Retracted Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature (2010) 1.92
The histone H1 family: specific members, specific functions? Biol Chem (2008) 1.91
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Methods Enzymol (2012) 1.83
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81
The moving parts of the nucleolus. Histochem Cell Biol (2005) 1.81
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Mol Cell (2012) 1.79
Molecular mechanisms of gene silencing mediated by DNA methylation. Mol Cell Biol (2002) 1.73
A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev (2006) 1.70
A 3-year study of addiction mutual-help group participation following intensive outpatient treatment. Alcohol Clin Exp Res (2006) 1.61
Bone disease in thalassemia: a frequent and still unresolved problem. J Bone Miner Res (2009) 1.61
Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J (2007) 1.55
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development (2008) 1.54
The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol (2006) 1.52
A mixed integer linear optimization framework for the identification and quantification of targeted post-translational modifications of highly modified proteins using multiplexed electron transfer dissociation tandem mass spectrometry. Mol Cell Proteomics (2009) 1.51
The significance, development and progress of high-throughput combinatorial histone code analysis. Cell Mol Life Sci (2010) 1.51
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J Biol Chem (2006) 1.50
Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Mol Cell Biol (2009) 1.49
Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem (2002) 1.45
Comparison of the dimensional accuracy of injection-molded denture base materials to that of conventional pressure-pack acrylic resin. J Prosthodont (2004) 1.41
Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer. Cell (2013) 1.40
Breaking the histone code with quantitative mass spectrometry. Expert Rev Proteomics (2011) 1.39
Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Mol Cell Proteomics (2009) 1.39
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol (2010) 1.39
A structural link between inactivation and block of a K+ channel. Nat Struct Mol Biol (2008) 1.36
Targeting histone modifications--epigenetics in cancer. Curr Opin Cell Biol (2013) 1.36
Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator. J Virol (2004) 1.34
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nat Cell Biol (2013) 1.33
Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval. J Proteome Res (2009) 1.33
Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs. Mol Cell (2002) 1.30
JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress. EMBO J (2011) 1.28
Proton radiotherapy for orbital rhabdomyosarcoma: clinical outcome and a dosimetric comparison with photons. Int J Radiat Oncol Biol Phys (2005) 1.28
Nucleocytoplasmic shuttling of the retinoblastoma tumor suppressor protein via Cdk phosphorylation-dependent nuclear export. J Biol Chem (2006) 1.28
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proc Natl Acad Sci U S A (2012) 1.28
Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivity. EMBO J (2009) 1.26
Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nat Struct Mol Biol (2013) 1.26
Proteomic characterization of novel histone post-translational modifications. Epigenetics Chromatin (2013) 1.26
Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol (2006) 1.25
Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents. Cancer Res (2007) 1.24
Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy. J Am Chem Soc (2009) 1.23
Quantitative assessment of range fluctuations in charged particle lung irradiation. Int J Radiat Oncol Biol Phys (2007) 1.22
Global secretome analysis identifies novel mediators of bone metastasis. Cell Res (2012) 1.22
FBPs are calibrated molecular tools to adjust gene expression. Mol Cell Biol (2006) 1.21
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics (2012) 1.19
Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19
Quantitative dynamics of the link between cellular metabolism and histone acetylation. J Biol Chem (2013) 1.19
Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells. Nat Commun (2012) 1.18
The MRG domain mediates the functional integration of MSL3 into the dosage compensation complex. Mol Cell Biol (2005) 1.18