Published in Cancer Res on October 15, 2006
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene (2009) 8.01
Interdependence of hypoxic and innate immune responses. Nat Rev Immunol (2009) 3.29
The ubiquitin system, disease, and drug discovery. BMC Biochem (2008) 1.73
The microenvironment of AIDS-related diffuse large B-cell lymphoma provides insight into the pathophysiology and indicates possible therapeutic strategies. Blood (2013) 1.62
HIF transcription factors, inflammation, and immunity. Immunity (2014) 1.55
Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma. Br J Cancer (2011) 1.22
Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes. Oncogene (2014) 1.14
Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1alpha/VEGF signaling pathways in human breast cancer cells. Int J Cancer (2010) 1.06
Targeting Epstein-Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy. Oncogene (2014) 1.04
IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells. J Immunol (2008) 1.02
Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells. Cell Death Dis (2013) 1.01
MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling. J Virol (2006) 0.99
Phosphorylated ezrin is associated with EBV latent membrane protein 1 in nasopharyngeal carcinoma and induces cell migration. Oncogene (2009) 0.98
Retracted Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells. Biochem J (2007) 0.96
Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect. PLoS One (2012) 0.94
SIAH-1 interacts with the Kaposi's sarcoma-associated herpesvirus-encoded ORF45 protein and promotes its ubiquitylation and proteasomal degradation. J Virol (2007) 0.91
Upregulation of special AT-rich-binding protein 1 by Epstein-Barr virus latent membrane protein 1 in human nasopharyngeal cells and nasopharyngeal cancer. J Gen Virol (2012) 0.89
Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome. J Biomed Sci (2009) 0.89
X-box binding protein 1 contributes to induction of the Kaposi's sarcoma-associated herpesvirus lytic cycle under hypoxic conditions. J Virol (2009) 0.88
Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter. Cancer Gene Ther (2010) 0.87
miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis. Mol Cancer (2014) 0.86
A mechanism for induction of a hypoxic response by vaccinia virus. Proc Natl Acad Sci U S A (2013) 0.84
Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1alpha protein accumulation and vascular endothelial growth factor expression in human breast cancer cells. Acta Pharmacol Sin (2009) 0.83
Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation. Invest New Drugs (2009) 0.82
Hypoxia-Inducible Factor (HIF) as a Pharmacological Target for Prevention and Treatment of Infectious Diseases. Infect Dis Ther (2014) 0.82
Role of the ubiquitin system and tumor viruses in AIDS-related cancer. BMC Biochem (2007) 0.80
Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol (2009) 0.79
Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity. J Immunol Res (2016) 0.78
Understanding the interplay between host immunity and Epstein-Barr virus in NPC patients. Emerg Microbes Infect (2015) 0.78
The role of the tumor microenvironment in HIV-associated lymphomas. Biomark Med (2015) 0.77
EBV reactivation as a target of luteolin to repress NPC tumorigenesis. Oncotarget (2016) 0.77
Epstein-Barr virus latent membrane protein 1 is not associated with vessel density nor with hypoxia inducible factor 1 alpha expression in nasopharyngeal carcinoma tissue. Head Neck Pathol (2009) 0.76
Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells. Oncotarget (2016) 0.75
Progression of understanding for the role of Epstein-Barr virus and management of nasopharyngeal carcinoma. Cancer Metastasis Rev (2017) 0.75
Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration. J Biol Chem (2003) 2.08
Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma. Cancer Res (2007) 1.69
Structure and function of IRF-7. J Interferon Cytokine Res (2002) 1.53
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors. Cancer Res (2004) 1.50
Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling. J Biol Chem (2005) 1.45
Interferon regulatory factor 7 regulates expression of Epstein-Barr virus latent membrane protein 1: a regulatory circuit. J Virol (2003) 1.42
Malignant myoepithelioma arising from recurrent pleomorphic adenoma of minor salivary gland. Auris Nasus Larynx (2002) 1.39
Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1. Oncogene (2005) 1.34
Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha. Mol Cell Biol (2004) 1.33
Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity factor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94. J Virol (2002) 1.30
Expression of DNA methyltransferase 1 is activated by hepatitis B virus X protein via a regulatory circuit involving the p16INK4a-cyclin D1-CDK 4/6-pRb-E2F1 pathway. Cancer Res (2007) 1.26
TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1. Mol Cell Biol (2008) 1.25
Epstein-Barr virus-encoded protein kinase (BGLF4) is involved in production of infectious virus. J Virol (2007) 1.23
Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination. Mol Cell Biol (2007) 1.23
Current understanding and management of nasopharyngeal carcinoma. Auris Nasus Larynx (2011) 1.20
Conserved herpesvirus protein kinases. Biochim Biophys Acta (2007) 1.17
Malignant phosphaturic mesenchymal tumor, mixed connective tissue variant of the tongue. Auris Nasus Larynx (2008) 1.17
Bilateral vocal cord paralysis caused by laryngeal mask airway. Am J Otolaryngol (2007) 1.16
Hyperphosphorylation of EBNA2 by Epstein-Barr virus protein kinase suppresses transactivation of the LMP1 promoter. J Virol (2005) 1.15
Targeting of host-cell ubiquitin pathways by viruses. Essays Biochem (2005) 1.14
The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production. J Virol (2010) 1.12
Epstein-Barr virus latent membrane protein 1 induces cancer stem/progenitor-like cells in nasopharyngeal epithelial cell lines. J Virol (2011) 1.11
Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells. Mol Biol Cell (2002) 1.09
Nationwide groundwater surveillance of noroviruses in South Korea, 2008. Appl Environ Microbiol (2010) 1.09
Epstein-Barr virus activates beta-catenin in type III latently infected B lymphocyte lines: association with deubiquitinating enzymes. Proc Natl Acad Sci U S A (2003) 1.08
Epstein-Barr virus infections: prospects for treatment. J Antimicrob Chemother (2005) 1.08
The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity. J Virol (2009) 1.06
Positive reciprocal regulation of ubiquitin C-terminal hydrolase L1 and beta-catenin/TCF signaling. PLoS One (2009) 1.06
Interferon regulatory factor 7 is associated with Epstein-Barr virus-transformed central nervous system lymphoma and has oncogenic properties. J Virol (2004) 1.05
Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b. Cancer Lett (2007) 1.04
New associations of human papillomavirus, Simian virus 40, and Epstein-Barr virus with human cancer. J Natl Cancer Inst (2002) 1.03
A solitary fibrous tumor arising in the parapharyngeal space, with MRI and FDG-PET findings. Auris Nasus Larynx (2008) 1.02
Expression and functional studies of ubiquitin C-terminal hydrolase L1 regulated genes. PLoS One (2009) 1.02
Tumor viruses and cell signaling pathways: deubiquitination versus ubiquitination. Mol Cell Biol (2004) 1.02
Prognostic factors for squamous cell carcinoma of the temporal bone: extensive bone involvement or extensive soft tissue involvement? Acta Otolaryngol (2009) 1.02
Multiple signal transducers and activators of transcription are induced by EBV LMP-1. Virology (2004) 1.01
Up-regulation of beta-catenin by a viral oncogene correlates with inhibition of the seven in absentia homolog 1 in B lymphoma cells. Proc Natl Acad Sci U S A (2005) 1.00
Pathogenic role of Epstein-Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma. Cancer Lett (2013) 1.00
Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma. Int J Cancer (2005) 1.00
Recent advances in the regulation of matrix metalloproteinase 2 activation: from basic research to clinical implication (Review). Oncol Rep (2002) 0.99
MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling. J Virol (2006) 0.99
Warthin's tumor associated with IgG4-related disease. Auris Nasus Larynx (2012) 0.99
Impact of MDM2 single nucleotide polymorphism on tumor onset in head and neck squamous cell carcinoma. Acta Otolaryngol (2008) 0.98
Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit. J Virol (2005) 0.98
Epstein-barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2. Cancer Res (2002) 0.98
Epstein-Barr virus latent membrane protein 1 promotes concentration in multivesicular bodies of fibroblast growth factor 2 and its release through exosomes. Int J Cancer (2007) 0.98
Maribavir inhibits epstein-barr virus transcription in addition to viral DNA replication. J Virol (2009) 0.97
Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation. Cancer Lett (2012) 0.97
Cooperative repression of cyclin-dependent kinase inhibitor p21 gene expression by hepatitis B virus X protein and hepatitis C virus core protein. FEBS Lett (2002) 0.97
Aberrant internal carotid artery as a cause of objective pulsatile tinnitus. Auris Nasus Larynx (2006) 0.97
Interferon regulatory factor 7 is negatively regulated by the Epstein-Barr virus immediate-early gene, BZLF-1. J Virol (2005) 0.96
Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene. Nucleic Acids Res (2004) 0.96
Herpes-virus infection in patients with Langerhans cell histiocytosis: a case-controlled sero-epidemiological study, and in situ analysis. PLoS One (2008) 0.96
Ubiquitin editing enzyme UCH L1 and microtubule dynamics: implication in mitosis. Cell Cycle (2010) 0.96
The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7. J Virol (2010) 0.96
Endoscopic nasopharyngectomy for patients with recurrent nasopharyngeal carcinoma at the primary site. Laryngoscope (2005) 0.95
Epstein-Barr virus latent membrane protein 1 suppresses the growth-inhibitory effect of retinoic acid by inhibiting retinoic acid receptor-beta2 expression via DNA methylation. Cancer Lett (2008) 0.94
Epstein-Barr virus BPLF1 deubiquitinates PCNA and attenuates polymerase η recruitment to DNA damage sites. J Virol (2012) 0.94
Epstein-Barr virus (EBV) latent membrane protein 1 induces interleukin-8 through the nuclear factor-kappa B signaling pathway in EBV-infected nasopharyngeal carcinoma cell line. Laryngoscope (2004) 0.94
Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter. Mol Cell Biol (2004) 0.93
Activation of the human endogenous retrovirus W long terminal repeat by herpes simplex virus type 1 immediate early protein 1. Mol Cells (2003) 0.93
Neuroprotective effects of TJ-23 (Tokishakuyakusan) on adult rat motoneurons following peripheral facial nerve axotomy. Otolaryngol Head Neck Surg (2007) 0.92
Prevalence of human papillomavirus in oropharyngeal cancer: a multicenter study in Japan. Oncology (2014) 0.92
Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner. J Immunol (2007) 0.91
PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts. Blood (2008) 0.90
Epstein-Barr virus latent membrane protein 1 (LMP1) C-terminal-activating region 3 contributes to LMP1-mediated cellular migration via its interaction with Ubc9. J Virol (2011) 0.90
Effects of maribavir and selected indolocarbazoles on Epstein-Barr virus protein kinase BGLF4 and on viral lytic replication. Antimicrob Agents Chemother (2004) 0.90
Epstein-Barr virus induces invasion and metastasis factors. Anticancer Res (2003) 0.90
Risk factors for adjacent segment disease after posterior lumbar interbody fusion and efficacy of simultaneous decompression surgery for symptomatic adjacent segment disease. J Spinal Disord Tech (2014) 0.90
MR findings of nine cases of palatal tumor. Magn Reson Med Sci (2005) 0.89
A single nucleotide polymorphism in the matrix metalloproteinase-1 and interleukin-8 gene promoter predicts poor prognosis in tongue cancer. Auris Nasus Larynx (2008) 0.89