Published in Clin Infect Dis on October 13, 2006
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Interventions to curb the overuse of Acid-suppressive medications on an inpatient general medicine service. P T (2010) 0.80
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Clostridium difficile-associated diarrhea in a tertiary care medical center. Proc (Bayl Univ Med Cent) (2010) 0.77
Absence of gastrointestinal infections in a cohort of patients with Zollinger-Ellison syndrome and other acid hypersecretors receiving long-term acid suppression with lansoprazole. BMC Gastroenterol (2008) 0.77
Inappropriate Use of Intravenous PPI for Stress Ulcer Prophylaxis in an Inner City Community Hospital. J Clin Med Res (2010) 0.77
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Identification of severe acute respiratory syndrome in Canada. N Engl J Med (2003) 14.29
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. N Engl J Med (2004) 11.44
Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone. CMAJ (2009) 9.83
Unintended medication discrepancies at the time of hospital admission. Arch Intern Med (2005) 8.94
Outpatient gatifloxacin therapy and dysglycemia in older adults. N Engl J Med (2006) 7.01
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. N Engl J Med (2002) 6.22
A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ (2009) 6.21
Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA (2009) 6.06
Hyperbaric oxygen for carbon monoxide poisoning : a systematic review and critical analysis of the evidence. Toxicol Rev (2005) 5.75
Risk of incident diabetes among patients treated with statins: population based study. BMJ (2013) 5.40
Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. Clin Infect Dis (2007) 5.39
Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study. Ann Intern Med (2013) 5.34
Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA (2011) 5.33
Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study. BMJ (2010) 4.73
Neisseria gonorrhoeae treatment failure and susceptibility to cefixime in Toronto, Canada. JAMA (2013) 4.69
A substantial and confusing variation exists in handling of baseline covariates in randomized controlled trials: a review of trials published in leading medical journals. J Clin Epidemiol (2009) 4.48
Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort study. BMJ (2009) 4.44
Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. Ann Intern Med (2013) 4.35
Thiazolidinediones and cardiovascular outcomes in older patients with diabetes. JAMA (2007) 4.25
Clustering of opioid prescribing and opioid-related mortality among family physicians in Ontario. Can Fam Physician (2011) 4.13
Opioid dose and drug-related mortality in patients with nonmalignant pain. Arch Intern Med (2011) 4.11
Drug-drug interactions among elderly patients hospitalized for drug toxicity. JAMA (2003) 4.00
A comparison of propensity score methods: a case-study estimating the effectiveness of post-AMI statin use. Stat Med (2006) 3.87
Long-term analgesic use after low-risk surgery: a retrospective cohort study. Arch Intern Med (2012) 3.52
Antipsychotic drugs and hyperglycemia in older patients with diabetes. Arch Intern Med (2009) 3.43
An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections. Nat Med (2002) 3.39
Drugs and the QT interval - caveat doctor. N Engl J Med (2004) 3.29
Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA (2004) 3.14
Drug-induced lithium toxicity in the elderly: a population-based study. J Am Geriatr Soc (2004) 3.12
Medical illness and the risk of suicide in the elderly. Arch Intern Med (2004) 3.09
Triple reassortant H3N2 influenza A viruses, Canada, 2005. Emerg Infect Dis (2006) 3.05
Risk-treatment mismatch in the pharmacotherapy of heart failure. JAMA (2005) 3.05
West Nile virus infection in 2002: morbidity and mortality among patients admitted to hospital in southcentral Ontario. CMAJ (2003) 3.03
Capitation and enhanced fee-for-service models for primary care reform: a population-based evaluation. CMAJ (2009) 2.90
Statins and the risk of herpes zoster: a population-based cohort study. Clin Infect Dis (2013) 2.74
The risk of suicide with selective serotonin reuptake inhibitors in the elderly. Am J Psychiatry (2006) 2.74
At the threshold: defining clinically meaningful resistance thresholds for antibiotic choice in community-acquired pneumonia. Clin Infect Dis (2008) 2.71
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. Proc Natl Acad Sci U S A (2014) 2.63
Predicting antimicrobial resistance in invasive pneumococcal infections. Clin Infect Dis (2005) 2.59
Trends in opioid use and dosing among socio-economically disadvantaged patients. Open Med (2011) 2.51
Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics. Proc Natl Acad Sci U S A (2010) 2.43
Facing up to the prescription opioid crisis. BMJ (2011) 2.43
The burden of premature opioid-related mortality. Addiction (2014) 2.42
Managing skin and soft tissue infections: expert panel recommendations on key decision points. J Antimicrob Chemother (2003) 2.41
Testing multiple statistical hypotheses resulted in spurious associations: a study of astrological signs and health. J Clin Epidemiol (2006) 2.35
Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections. Proc Natl Acad Sci U S A (2004) 2.32
The use of the propensity score for estimating treatment effects: administrative versus clinical data. Stat Med (2005) 2.31
Variation in nursing home antipsychotic prescribing rates. Arch Intern Med (2007) 2.30
Genetic variability of human respiratory syncytial virus A strains circulating in Ontario: a novel genotype with a 72 nucleotide G gene duplication. PLoS One (2012) 2.21
Trimethoprim-sulfamethoxazole induced hyperkalaemia in elderly patients receiving spironolactone: nested case-control study. BMJ (2011) 2.20
Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly. Arch Intern Med (2003) 2.18
Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units. J Infect Dis (2005) 2.03
Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB. Mol Microbiol (2004) 1.99
Outcomes assessment of the surgical management of esophageal cancer in younger and older patients. Ann Thorac Surg (2012) 1.96
Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. PLoS Med (2009) 1.94
The striking effect of the Heart Outcomes Prevention Evaluation (HOPE) on ramipril prescribing in Ontario. CMAJ (2003) 1.94
Severe group a streptococcal soft-tissue infections in Ontario: 1992-1996. Clin Infect Dis (2002) 1.93
New fibrate use and acute renal outcomes in elderly adults: a population-based study. Ann Intern Med (2012) 1.91
Sex-and age-based differences in the delivery and outcomes of critical care. CMAJ (2007) 1.91
Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes. J Bacteriol (2005) 1.90
Hemorrhage during warfarin therapy associated with cotrimoxazole and other urinary tract anti-infective agents: a population-based study. Arch Intern Med (2010) 1.87
New Delhi metallo-beta-lactamase, Ontario, Canada. Emerg Infect Dis (2011) 1.81
Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. nov. within the human pathogenic fungus Blastomyces dermatitidis. PLoS One (2013) 1.79
Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia. Clin Infect Dis (2010) 1.78
Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous polyspecific immunoglobulin together with a conservative surgical approach. Scand J Infect Dis (2005) 1.75
Clostridium difficile infection in hospitals: a brewing storm. CMAJ (2004) 1.74
New Delhi metallo-β-lactamase-1: local acquisition in Ontario, Canada, and challenges in detection. CMAJ (2011) 1.73
Use of other opioids during methadone therapy: a population-based study. Addiction (2012) 1.72
Modulation of bacterial growth by tumor necrosis factor-alpha in vitro and in vivo. Am J Respir Crit Care Med (2003) 1.70
Treatment of Barrett's esophagus with early neoplasia: a comparison of endoscopic therapy and esophagectomy. Gastrointest Endosc (2008) 1.69
Rates of hemorrhage during warfarin therapy for atrial fibrillation. CMAJ (2012) 1.68
Clinical and epidemiologic features of group a streptococcal pneumonia in Ontario, Canada. Arch Intern Med (2003) 1.67
FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother (2011) 1.66
The risk of postpartum hemorrhage with selective serotonin reuptake inhibitors and other antidepressants. J Clin Psychopharmacol (2008) 1.66
Persistence with therapy among patients treated with warfarin for atrial fibrillation. Arch Intern Med (2012) 1.65