Mechanisms of endotoxin neutralization by synthetic cationic compounds.

PubWeight™: 0.91‹?›

🔗 View Article (PMID 17059690)

Published in J Endotoxin Res on January 01, 2006

Authors

Jörg Andrä1, Thomas Gutsmann, Patrick Garidel, Klaus Brandenburg

Author Affiliations

1: Forschungszentrum Borstel, Biophysics Division, Leibniz-Zentrum für Medizin und Biowissenschaften, Borstel, Germany.

Articles by these authors

The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II. Mol Microbiol (2006) 2.53

Sacrificial bonds and hidden length: unraveling molecular mesostructures in tough materials. Biophys J (2005) 1.61

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. J Biol Chem (2008) 1.56

Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation. Mol Microbiol (2008) 1.56

Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses. Biochem J (2004) 1.52

Strategies for the assessment of protein aggregates in pharmaceutical biotech product development. Pharm Res (2010) 1.35

Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem J (2005) 1.28

The lipopolysaccharide of Brucella abortus BvrS/BvrR mutants contains lipid A modifications and has higher affinity for bactericidal cationic peptides. J Bacteriol (2005) 1.17

The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition. PLoS Pathog (2012) 1.17

New antiseptic peptides to protect against endotoxin-mediated shock. Antimicrob Agents Chemother (2010) 1.14

Biophysical characterization of endotoxin inactivation by NK-2, an antimicrobial peptide derived from mammalian NK-lysin. Antimicrob Agents Chemother (2004) 1.11

Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT. Eur J Biochem (2002) 1.11

Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors. Antimicrob Agents Chemother (2013) 1.06

A new class of synthetic peptide inhibitors blocks attachment and entry of human pathogenic viruses. J Infect Dis (2012) 1.05

Cyclic antimicrobial peptides based on Limulus anti-lipopolysaccharide factor for neutralization of lipopolysaccharide. Biochem Pharmacol (2004) 1.05

Physicochemical properties of bacterial glycopolymers in relation to bioactivity. Carbohydr Res (2003) 1.04

Biophysical mechanisms of endotoxin neutralization by cationic amphiphilic peptides. Biophys J (2011) 1.03

Phospholipids inhibit lipopolysaccharide (LPS)-induced cell activation: a role for LPS-binding protein. J Immunol (2005) 1.03

Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins. Eur J Biochem (2002) 1.03

Mechanism of interaction of optimized Limulus-derived cyclic peptides with endotoxins: thermodynamic, biophysical and microbiological analysis. Biochem J (2007) 1.02

Antimicrobial peptides and their potential application in inflammation and sepsis. Crit Care (2012) 1.02

Investigation into the interaction of recombinant human serum albumin with Re-lipopolysaccharide and lipid A. J Endotoxin Res (2002) 1.02

Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra. J Biol Chem (2008) 1.00

Cell membrane array fabrication and assay technology. BMC Biotechnol (2005) 1.00

Structural requirements of the Pseudomonas quinolone signal for membrane vesicle stimulation. J Bacteriol (2009) 1.00

Correlation of AFM and SFA measurements concerning the stability of supported lipid bilayers. Biophys J (2004) 0.99

Temperature dependence of the binding of endotoxins to the polycationic peptides polymyxin B and its nonapeptide. Biophys J (2004) 0.99

Divalent cations affect chain mobility and aggregate structure of lipopolysaccharide from Salmonella minnesota reflected in a decrease of its biological activity. Biochim Biophys Acta (2005) 0.99

The acyl group as the central element of the structural organization of antimicrobial lipopeptide. J Am Chem Soc (2007) 0.98

Chemical synthesis of a glycolipid library by a solid-phase strategy allows elucidation of the structural specificity of immunostimulation by rhamnolipids. Chemistry (2006) 0.98

Quantitative determination of ion distributions in bacterial lipopolysaccharide membranes by grazing-incidence X-ray fluorescence. Proc Natl Acad Sci U S A (2010) 0.98

Multiple peptide resistance factor (MprF)-mediated Resistance of Staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol. J Biol Chem (2011) 0.97

Structural rearrangement of model membranes by the peptide antibiotic NK-2. Biochim Biophys Acta (2005) 0.97

Innate recognition of bacteria: engagement of multiple receptors. Crit Rev Immunol (2002) 0.96

Localization of the lipopolysaccharide-binding protein in phospholipid membranes by atomic force microscopy. J Biol Chem (2005) 0.94

Structural features governing the activity of lactoferricin-derived peptides that act in synergy with antibiotics against Pseudomonas aeruginosa in vitro and in vivo. Antimicrob Agents Chemother (2010) 0.94

Endotoxin-like properties of a rhamnolipid exotoxin from Burkholderia (Pseudomonas) plantarii: immune cell stimulation and biophysical characterization. Biol Chem (2006) 0.94

Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat. J Biol Chem (2012) 0.94

Investigations into the polymorphism of rat tail tendon fibrils using atomic force microscopy. Biochem Biophys Res Commun (2003) 0.94

Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens. J Biol Chem (2007) 0.93

Biophysical characterization of the interaction of Limulus polyphemus endotoxin neutralizing protein with lipopolysaccharide. Eur J Biochem (2004) 0.93

The physicochemistry of endotoxins in relation to bioactivity. Int J Med Microbiol (2007) 0.92

Structure and mode of action of the antimicrobial peptide arenicin. Biochem J (2008) 0.92

Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus. Antimicrob Agents Chemother (2009) 0.92

Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Microbiol (2008) 0.92

Cross-linked hemoglobin converts endotoxically inactive pentaacyl endotoxins into a physiologically active conformation. J Biol Chem (2003) 0.91

Transfection efficiency and cytotoxicity of nonviral gene transfer reagents in human smooth muscle and endothelial cells. Pharm Res (2004) 0.91

Surface acoustic wave biosensor as a tool to study the interaction of antimicrobial peptides with phospholipid and lipopolysaccharide model membranes. Langmuir (2008) 0.91

Thermodynamic analysis of the lipopolysaccharide-dependent resistance of gram-negative bacteria against polymyxin B. Biophys J (2007) 0.91

Molecular basis for membrane selectivity of NK-2, a potent peptide antibiotic derived from NK-lysin. Biochim Biophys Acta (2003) 0.91

Surfactant protein a inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide-binding protein. Am J Respir Cell Mol Biol (2002) 0.91

Towards antibacterial strategies: studies on the mechanisms of interaction between antibacterial peptides and model membranes. J Endotoxin Res (2003) 0.90

The anti-inflammatory effect of the synthetic antimicrobial peptide 19-2.5 in a murine sepsis model: a prospective randomized study. Crit Care (2013) 0.89

Temperature-induced changes in the lipopolysaccharide of Yersinia pestis affect plasminogen activation by the pla surface protease. Infect Immun (2010) 0.89

Physicochemical and biological analysis of synthetic bacterial lipopeptides: validity of the concept of endotoxic conformation. J Biol Chem (2007) 0.89

Calcium adsorption and displacement: characterization of lipid monolayers and their interaction with membrane-active peptides/proteins. BMC Biochem (2006) 0.88

Giant bent-core mesogens in the thread forming process of marine mussels. Biomacromolecules (2004) 0.88

Crucial roles of charged saccharide moieties in survival of gram negative bacteria against protamine revealed by combination of grazing incidence x-ray structural characterizations and Monte Carlo simulations. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 0.88

Biophysical analysis of the interaction of granulysin-derived peptides with enterobacterial endotoxins. Biochim Biophys Acta (2007) 0.88

Lipopolysaccharide interaction is decisive for the activity of the antimicrobial peptide NK-2 against Escherichia coli and Proteus mirabilis. Biochem J (2010) 0.87

Lysozyme-lysozyme self-interactions as assessed by the osmotic second virial coefficient: impact for physical protein stabilization. Biotechnol J (2009) 0.86

Effects of specific versus nonspecific ionic interactions on the structure and lateral organization of lipopolysaccharides. Biophys J (2011) 0.86

Lipid-specific membrane activity of human beta-defensin-3. Biochemistry (2006) 0.86

The generalized endotoxic principle. Eur J Immunol (2003) 0.86

Insights into protein-polysorbate interactions analysed by means of isothermal titration and differential scanning calorimetry. Eur Biophys J (2009) 0.86

Peptide-based treatment of sepsis. Appl Microbiol Biotechnol (2011) 0.85

Effect of matrix elasticity on the maintenance of the chondrogenic phenotype. Tissue Eng Part A (2010) 0.85

A critical evaluation of self-interaction chromatography as a predictive tool for the assessment of protein-protein interactions in protein formulation development: a case study of a therapeutic monoclonal antibody. Eur J Pharm Biopharm (2010) 0.85

Physicochemical characterization of the endotoxins from Coxiella burnetii strain Priscilla in relation to their bioactivities. BMC Biochem (2004) 0.84

Boosting antibody developability through rational sequence optimization. MAbs (2015) 0.84

Biophysical characterization of synthetic rhamnolipids. FEBS J (2006) 0.84

Conformational analysis of protein secondary structure during spray-drying of antibody/mannitol formulations. Eur J Pharm Biopharm (2006) 0.83

Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins. Innate Immun (2008) 0.83

Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes. Eur Biophys J (2004) 0.83

Investigations into the mechanisms used by the C-terminal anchors of Escherichia coli penicillin-binding proteins 4, 5, 6 and 6b for membrane interaction. Eur J Biochem (2002) 0.82

Significance of the cyclic structure and of arginine residues for the antibacterial activity of arenicin-1 and its interaction with phospholipid and lipopolysaccharide model membranes. Biol Chem (2009) 0.82

Probing the properties of lipopolysaccharide monolayers and their interaction with the antimicrobial peptide polymyxin B by atomic force microscopy. Langmuir (2005) 0.82

Bacterial cell wall compounds as promising targets of antimicrobial agents I. Antimicrobial peptides and lipopolyamines. Curr Drug Targets (2012) 0.82

Morphology, size distribution, and aggregate structure of lipopolysaccharide and lipid A dispersions from enterobacterial origin. Innate Immun (2010) 0.82

Interaction of lipopolysaccharide and phospholipid in mixed membranes: solid-state 31P-NMR spectroscopic and microscopic investigations. Biophys J (2008) 0.82

Stabilized nonviral formulations for the delivery of MCP-1 gene into cells of the vasculoendothelial system. Pharm Res (2004) 0.82