William Martin

Author PubWeight™ 183.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Reading the entrails of chickens: molecular timescales of evolution and the illusion of precision. Trends Genet 2004 17.22
2 Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements. PLoS Biol 2004 7.95
3 Endosymbiotic gene transfer: organelle genomes forge eukaryotic chromosomes. Nat Rev Genet 2004 5.51
4 Eukaryotic evolution, changes and challenges. Nature 2006 5.10
5 The energetics of genome complexity. Nature 2010 4.58
6 Genetics and geography of wild cereal domestication in the near east. Nat Rev Genet 2002 3.30
7 Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution. Proc Natl Acad Sci U S A 2008 2.97
8 Molecular poltergeists: mitochondrial DNA copies (numts) in sequenced nuclear genomes. PLoS Genet 2010 2.70
9 Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes". Blood 2008 2.50
10 The evolutionary root of flowering plants. Syst Biol 2012 2.46
11 A genome phylogeny for mitochondria among alpha-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes. Mol Biol Evol 2004 2.32
12 The tree of one percent. Genome Biol 2006 2.23
13 Prokaryotic evolution and the tree of life are two different things. Biol Direct 2009 2.17
14 On the origin of genomes and cells within inorganic compartments. Trends Genet 2005 2.04
15 Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution. Proc Natl Acad Sci U S A 2007 1.96
16 The rocky roots of the acetyl-CoA pathway. Trends Biochem Sci 2004 1.92
17 Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants 2004 1.84
18 Acceleration of genomic evolution caused by enhanced mutation rate in endocellular symbionts. Proc Natl Acad Sci U S A 2002 1.79
19 Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics. Clin Immunol 2009 1.73
20 Genes of cyanobacterial origin in plant nuclear genomes point to a heterocyst-forming plastid ancestor. Mol Biol Evol 2008 1.62
21 Directed networks reveal genomic barriers and DNA repair bypasses to lateral gene transfer among prokaryotes. Genome Res 2011 1.58
22 HIV vaccine development by computer assisted design: the GAIA vaccine. Vaccine 2005 1.56
23 Radiofrequency ablation for persistent atrial fibrillation in patients with advanced heart failure and severe left ventricular systolic dysfunction: a randomised controlled trial. Heart 2010 1.54
24 Mitochondria as we don't know them. Trends Biochem Sci 2002 1.49
25 Haplotype structure at seven barley genes: relevance to gene pool bottlenecks, phylogeny of ear type and site of barley domestication. Mol Genet Genomics 2006 1.49
26 Testing hypotheses without considering predictions. Bioessays 2007 1.48
27 A unique set of 11,008 onion expressed sequence tags reveals expressed sequence and genomic differences between the monocot orders Asparagales and Poales. Plant Cell 2003 1.46
28 Immuno-informatics: Mining genomes for vaccine components. Immunol Cell Biol 2002 1.46
29 Utility of the neutrophil to lymphocyte ratio in predicting long-term outcomes in acute decompensated heart failure. Am J Cardiol 2011 1.44
30 Networks of gene sharing among 329 proteobacterial genomes reveal differences in lateral gene transfer frequency at different phylogenetic depths. Mol Biol Evol 2010 1.42
31 A proteomic survey of Chlamydomonas reinhardtii mitochondria sheds new light on the metabolic plasticity of the organelle and on the nature of the alpha-proteobacterial mitochondrial ancestor. Mol Biol Evol 2009 1.41
32 Prognosis of endodontically treated teeth? Point. Quintessence Int 2003 1.39
33 Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design. Hum Vaccin Immunother 2013 1.38
34 Single eubacterial origin of eukaryotic sulfide:quinone oxidoreductase, a mitochondrial enzyme conserved from the early evolution of eukaryotes during anoxic and sulfidic times. Mol Biol Evol 2003 1.37
35 How did LUCA make a living? Chemiosmosis in the origin of life. Bioessays 2010 1.33
36 A positive definition of prokaryotes. Nature 2006 1.29
37 Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides. Proc Natl Acad Sci U S A 2004 1.28
38 Mutational decay and age of chloroplast and mitochondrial genomes transferred recently to angiosperm nuclear chromosomes. Plant Physiol 2005 1.27
39 Evolutionary biology: essence of mitochondria. Nature 2003 1.25
40 The origin of mitochondria in light of a fluid prokaryotic chromosome model. Biol Lett 2007 1.25
41 Transcriptomic evidence that longevity of acquired plastids in the photosynthetic slugs Elysia timida and Plakobranchus ocellatus does not entail lateral transfer of algal nuclear genes. Mol Biol Evol 2010 1.24
42 Pyruvate formate-lyase and a novel route of eukaryotic ATP synthesis in Chlamydomonas mitochondria. J Biol Chem 2006 1.22
43 Networks uncover hidden lexical borrowing in Indo-European language evolution. Proc Biol Sci 2010 1.18
44 Getting a better picture of microbial evolution en route to a network of genomes. Philos Trans R Soc Lond B Biol Sci 2009 1.15
45 Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4(+) T cells against the swine-origin H1N1 influenza virus. Vaccine 2011 1.14
46 166Ho-DOTMP radiation-absorbed dose estimation for skeletal targeted radiotherapy. J Nucl Med 2006 1.14
47 Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants. A case study of endosymbiotic gene transfer. Eur J Biochem 2002 1.12
48 Acetate formation in the energy metabolism of parasitic helminths and protists. Int J Parasitol 2010 1.11
49 Energy metabolism among eukaryotic anaerobes in light of Proterozoic ocean chemistry. Philos Trans R Soc Lond B Biol Sci 2008 1.11
50 HelicoVax: epitope-based therapeutic Helicobacter pylori vaccination in a mouse model. Vaccine 2011 1.09
51 Evolutionary biology: out of thin air. Nature 2007 1.09
52 Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach. Vaccine 2003 1.07
53 Utility of FDG-PET/CT in follow-up of children treated for Hodgkin and non-Hodgkin lymphoma. J Pediatr Hematol Oncol 2006 1.07
54 Epitope-based vaccination against pneumonic tularemia. Vaccine 2009 1.05
55 Difficulties in testing for covarion-like properties of sequences under the confounding influence of changing proportions of variable sites. Mol Biol Evol 2008 1.04
56 The difference between organelles and endosymbionts. Curr Biol 2006 1.03
57 Genome networks root the tree of life between prokaryotic domains. Genome Biol Evol 2010 1.02
58 Carvedilol alone or in combination with digoxin for the management of atrial fibrillation in patients with heart failure? J Am Coll Cardiol 2003 1.02
59 Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice. Curr Mol Med 2007 1.02
60 Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine. Methods 2004 1.00
61 Making vaccines "on demand": a potential solution for emerging pathogens and biodefense? Hum Vaccin Immunother 2013 1.00
62 Sulfide : quinone oxidoreductase (SQR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity. FEBS J 2008 1.00
63 Novel function of complement C3d as an autologous helper T-cell target. Immunol Cell Biol 2008 0.99
64 Acetate:succinate CoA-transferase in the hydrogenosomes of Trichomonas vaginalis: identification and characterization. J Biol Chem 2007 0.98
65 Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis. J Biol Chem 2004 0.98
66 Interspecific evolution: microbial symbiosis, endosymbiosis and gene transfer. Environ Microbiol 2003 0.97
67 ERAD components in organisms with complex red plastids suggest recruitment of a preexisting protein transport pathway for the periplastid membrane. Genome Biol Evol 2010 0.97
68 Euglena gracilis rhodoquinone:ubiquinone ratio and mitochondrial proteome differ under aerobic and anaerobic conditions. J Biol Chem 2004 0.96
69 Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV. Vaccine 2007 0.96
70 Ascorbate blocks endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation in the bovine ciliary vascular bed and rat mesentery. Br J Pharmacol 2002 0.96
71 Bifunctional aldehyde/alcohol dehydrogenase (ADHE) in chlorophyte algal mitochondria. Plant Mol Biol 2003 0.94
72 The evolution of eukaryotes. Science 2007 0.93
73 VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone. Vaccine 2010 0.92
74 A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM). J Biomed Biotechnol 2010 0.92
75 Dietary protein intake impacts human skeletal muscle protein fractional synthetic rates after endurance exercise. Am J Physiol Endocrinol Metab 2005 0.92
76 Euglena gracilis ribonucleotide reductase: the eukaryote class II enzyme and the possible antiquity of eukaryote B12 dependence. J Biol Chem 2005 0.91
77 Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease. J Clin Endocrinol Metab 2006 0.91
78 Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics. Expert Rev Clin Pharmacol 2013 0.91
79 The neglected genome. EMBO Rep 2012 0.90
80 The effect of progesterone on myometrial contractility, potassium channels, and tocolytic efficacy. Reprod Sci 2009 0.89
81 Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes. J Diabetes Res 2013 0.89
82 Evolutionary dynamics of introns in plastid-derived genes in plants: saturation nearly reached but slow intron gain continues. Mol Biol Evol 2007 0.89
83 Evolutionary deimmunization: an ancillary mechanism for self-tolerance? Cell Immunol 2007 0.89
84 A novel prokaryotic trans-2-enoyl-CoA reductase from the spirochete Treponema denticola. FEBS Lett 2007 0.89
85 Evolutionary biology: Early evolution comes full circle. Nature 2004 0.89
86 Protein import into hydrogenosomes of Trichomonas vaginalis involves both N-terminal and internal targeting signals: a case study of thioredoxin reductases. Eukaryot Cell 2008 0.88
87 Differential effects of ascorbate on endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation in the bovine ciliary vascular bed and coronary artery. Br J Pharmacol 2003 0.88
88 Immune response of mice transgenic for human histocompatibility leukocyte Antigen-DR to human thyrotropin receptor-extracellular domain. Thyroid 2009 0.87
89 Genome history in the symbiotic hybrid Euglena gracilis. Gene 2007 0.87
90 Sodium nitrite mitigates ventilator-induced lung injury in rats. Anesthesiology 2012 0.87
91 Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease. Hum Vaccin Immunother 2012 0.87
92 An audit of outcome in intravascular transfusions using the intrahepatic portion of the fetal umbilical vein compared to cordocentesis. Fetal Diagn Ther 2006 0.87
93 A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses. PLoS One 2012 0.87
94 Effects of a cementing technique in addition to luting agent on the uniaxial retention force of a single-tooth implant-supported restoration: an in vitro study. Int J Oral Maxillofac Implants 2011 0.86
95 Networks of lexical borrowing and lateral gene transfer in language and genome evolution. Bioessays 2013 0.85
96 From immunome to vaccine: epitope mapping and vaccine design tools. Novartis Found Symp 2003 0.85
97 Variability of wax ester fermentation in natural and bleached Euglena gracilis Strains in response to oxygen and the elongase inhibitor flufenacet. J Eukaryot Microbiol 2009 0.84
98 Rate and polarity of gene fusion and fission in Oryza sativa and Arabidopsis thaliana. Mol Biol Evol 2006 0.84
99 Supertrees and symbiosis in eukaryote genome evolution. Trends Microbiol 2007 0.83
100 Identification of prokaryotic homologues indicates an endosymbiotic origin for the alternative oxidases of mitochondria (AOX) and chloroplasts (PTOX). Gene 2004 0.83
101 A machine-learning approach reveals that alignment properties alone can accurately predict inference of lateral gene transfer from discordant phylogenies. Mol Biol Evol 2009 0.82
102 Pathogenic archaebacteria: do they not exist because archaebacteria use different vitamins? Bioessays 2004 0.82
103 Microbiology. Seeing green and red in diatom genomes. Science 2009 0.82
104 Restoration of disk height through non-surgical spinal decompression is associated with decreased discogenic low back pain: a retrospective cohort study. BMC Musculoskelet Disord 2010 0.82
105 Quantitative gated SPECT: the effect of reconstruction filter on calculated left ventricular ejection fractions and volumes. Phys Med Biol 2002 0.82
106 Progression of periacetabular osteolytic lesions. J Bone Joint Surg Am 2012 0.82
107 Chloroplast phosphoglycerate kinase from Euglena gracilis: endosymbiotic gene replacement going against the tide. Eur J Biochem 2004 0.81
108 Anaerobic animals from an ancient, anoxic ecological niche. BMC Biol 2010 0.81
109 Evolution of spliceosomal introns following endosymbiotic gene transfer. BMC Evol Biol 2010 0.81
110 Requirement for flow in the blockade of endothelium-derived hyperpolarizing factor (EDHF) by ascorbate in the bovine ciliary artery. Br J Pharmacol 2004 0.81
111 Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine in the rat aorta. Br J Pharmacol 2010 0.80
112 New imaging tools for the diagnosis of infection. Future Microbiol 2007 0.80
113 Evaluation of potassium ion as the endothelium-derived hyperpolarizing factor (EDHF) in the bovine coronary artery. Br J Pharmacol 2003 0.80
114 T cell epitope identification for bovine vaccines: an epitope mapping method for BoLA A-11. Int J Parasitol 2003 0.80
115 Ascorbate elevates perfusion pressure in the bovine extraocular long posterior ciliary artery: role of endothelium-derived hyperpolarizing factor (EDHF). Eur J Pharmacol 2006 0.79
116 Immune camouflage: relevance to vaccines and human immunology. Hum Vaccin Immunother 2014 0.79
117 Managing unmanageable physicians: leadership, stewardship and disruptive behavior. Physician Exec 2004 0.79
118 Comparing pink and white esthetic scores to layperson perception in the single-tooth implant patient. Int J Oral Maxillofac Implants 2014 0.79
119 The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease. J Clin Endocrinol Metab 2010 0.79
120 Stimulus-specific blockade of nitric oxide-mediated dilatation by asymmetric dimethylarginine (ADMA) and monomethylarginine (L-NMMA) in rat aorta and carotid artery. Eur J Pharmacol 2011 0.78
121 Dominance of flow-mediated constriction over flow-mediated dilatation in the rat carotid artery. Br J Pharmacol 2012 0.78
122 Detection of circular polarization in light scattered from photosynthetic microbes. Proc Natl Acad Sci U S A 2009 0.78
123 Multiples clinic: a model for antenatal care. Semin Fetal Neonatal Med 2010 0.78
124 Purification, microsequencing and cloning of spinach ATP-dependent phosphofructokinase link sequence and function for the plant enzyme. FEBS J 2007 0.78
125 Biphasic neurogenic vasodilatation in the bovine intraocular long posterior ciliary artery: involvement of nitric oxide and an additional unidentified neurotransmitter. Br J Pharmacol 2005 0.78
126 Analysis of ChimeriVax Japanese Encephalitis Virus envelope for T-cell epitopes and comparison to circulating strain sequences. Vaccine 2007 0.78
127 Oxidation by trace Cu2+ ions underlies the ability of ascorbate to induce vascular dysfunction in the rat perfused mesentery. Eur J Pharmacol 2009 0.78
128 Maternal obesity and its relationship with spontaneous and oxytocin-induced contractility of human myometrium in vitro. Reprod Sci 2009 0.78
129 Expression of nucleus-encoded genes for chloroplast proteins in the flagellate Euglena gracilis. J Eukaryot Microbiol 2009 0.77
130 Time for T?: Thoughts about the 2009 novel H1N1 influenza outbreak and the role of T cell epitopes in the next generation of influenza vaccines. Hum Vaccin 2010 0.77
131 Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides. Endocrinology 2013 0.77
132 Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide. Eur J Pharmacol 2002 0.77
133 New quinoline NK3 receptor antagonists with CNS activity. Bioorg Med Chem Lett 2008 0.77
134 A randomized, double-blind trial of pre-emptive local anesthesia in day-case knee arthroscopy. Arthroscopy 2003 0.77
135 I-123 MIBG cardiac uptake measurements: limitations of collimator choice and scatter correction in the clinical context. Nucl Med Commun 2010 0.76
136 Preoperative lymphoscintigraphy and internal mammary sentinel lymph node biopsy do not enhance the accuracy of lymphatic mapping for breast cancer. Am Surg 2004 0.76
137 Robert F. Furchgott, Nobel laureate (1916-2009)--a personal reflection. Br J Pharmacol 2009 0.76
138 Building better biotherapeutics and vaccines by design: EpiVax, Inc., an immunology company. R I Med J (2013) 2013 0.75
139 R-E-S-P-E-C-T: bedrock of satisfaction and effectiveness for organizations and individuals. Physician Exec 2004 0.75
140 On teaching governance. J Health Adm Educ 2006 0.75
141 Welcome to Genome Biology and Evolution. Genome Biol Evol 2009 0.75
142 Transketolase from Cyanophora paradoxa: in vitro import into cyanelles and pea chloroplasts and a complex history of a gene often, but not always, transferred in the context of secondary endosymbiosis. J Eukaryot Microbiol 2009 0.75
143 123I- Metaiodobenzylguanidine in chronic heart failure: Is there a clinical use? Nucl Med Commun 2006 0.75
144 Analysis of fine-mode aerosol retrieval capabilities by different passive remote sensing instrument designs. Opt Express 2012 0.75
145 The smoking gun of gene transfer. Nat Genet 2003 0.75