The tree of one percent.

PubWeight™: 2.23‹?› | Rank: Top 2%

🔗 View Article (PMC 1794558)

Published in Genome Biol on November 01, 2006

Authors

Tal Dagan1, William Martin

Author Affiliations

1: Institute of Botany, University of Düsseldorf, D-40225 Düsseldorf, Germany. tal.dagan@uni-duesseldorf.de

Articles citing this

The human phylome. Genome Biol (2007) 3.81

Pattern pluralism and the Tree of Life hypothesis. Proc Natl Acad Sci U S A (2007) 3.56

Search for a 'Tree of Life' in the thicket of the phylogenetic forest. J Biol (2009) 2.66

Clusters of orthologous genes for 41 archaeal genomes and implications for evolutionary genomics of archaea. Biol Direct (2007) 2.53

An archaeal origin of eukaryotes supports only two primary domains of life. Nature (2013) 2.31

Prokaryotic evolution and the tree of life are two different things. Biol Direct (2009) 2.17

Darwinian evolution in the light of genomics. Nucleic Acids Res (2009) 1.92

On the chimeric nature, thermophilic origin, and phylogenetic placement of the Thermotogales. Proc Natl Acad Sci U S A (2009) 1.78

Phylogenetic modeling of lateral gene transfer reconstructs the pattern and relative timing of speciations. Proc Natl Acad Sci U S A (2012) 1.66

Dealing with incongruence in phylogenomic analyses. Philos Trans R Soc Lond B Biol Sci (2008) 1.64

Genomic and Genetic Diversity within the Pseudomonas fluorescens Complex. PLoS One (2016) 1.58

The tree versus the forest: the fungal tree of life and the topological diversity within the yeast phylome. PLoS One (2009) 1.53

The dynamic nature of genomes across the tree of life. Genome Biol Evol (2014) 1.47

Similarity and differences in the Lactobacillus acidophilus group identified by polyphasic analysis and comparative genomics. J Bacteriol (2006) 1.46

Networks of gene sharing among 329 proteobacterial genomes reveal differences in lateral gene transfer frequency at different phylogenetic depths. Mol Biol Evol (2010) 1.42

The origin of eukaryotes and their relationship with the Archaea: are we at a phylogenomic impasse? Nat Rev Microbiol (2010) 1.40

Lateral gene transfer as a support for the tree of life. Proc Natl Acad Sci U S A (2012) 1.40

Bacterial genome instability. Microbiol Mol Biol Rev (2014) 1.31

On the origin of cells and viruses: primordial virus world scenario. Ann N Y Acad Sci (2009) 1.29

Eukaryogenesis, how special really? Proc Natl Acad Sci U S A (2015) 1.28

L-form bacteria, cell walls and the origins of life. Open Biol (2013) 1.26

Universally distributed single-copy genes indicate a constant rate of horizontal transfer. PLoS One (2011) 1.25

Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes. BMC Biol (2014) 1.21

Early bioenergetic evolution. Philos Trans R Soc Lond B Biol Sci (2013) 1.20

An evolutionary network of genes present in the eukaryote common ancestor polls genomes on eukaryotic and mitochondrial origin. Genome Biol Evol (2012) 1.14

The practice of classification and the theory of evolution, and what the demise of Charles Darwin's tree of life hypothesis means for both of them. Philos Trans R Soc Lond B Biol Sci (2009) 1.12

Statistics and truth in phylogenomics. Mol Biol Evol (2011) 1.12

Evolution of microbes and viruses: a paradigm shift in evolutionary biology? Front Cell Infect Microbiol (2012) 1.11

Abstract profiles of structural stability point to universal tendencies, family-specific factors, and ancient connections between languages. PLoS One (2012) 1.10

Genome beginnings: rooting the tree of life. Philos Trans R Soc Lond B Biol Sci (2009) 1.08

Analysis of rare genomic changes does not support the unikont-bikont phylogeny and suggests cyanobacterial symbiosis as the point of primary radiation of eukaryotes. Genome Biol Evol (2009) 1.05

The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life. PLoS One (2011) 1.05

Early evolution without a tree of life. Biol Direct (2011) 1.05

Global phylogenomic analysis disentangles the complex evolutionary history of DNA replication in archaea. Genome Biol Evol (2014) 1.03

Informational gene phylogenies do not support a fourth domain of life for nucleocytoplasmic large DNA viruses. PLoS One (2011) 1.03

Evolutionary history of bacteriophages with double-stranded DNA genomes. Biol Direct (2007) 1.02

Telling the whole story in a 10,000-genome world. Biol Direct (2011) 1.01

Trees in the web of life. J Biol (2009) 1.00

The origin of plastids. Philos Trans R Soc Lond B Biol Sci (2008) 1.00

The Public Goods Hypothesis for the evolution of life on Earth. Biol Direct (2011) 0.96

How reticulated are species? Bioessays (2015) 0.96

A rooted net of life. Biol Direct (2011) 0.96

Compelling reasons why viruses are relevant for the origin of cells. Nat Rev Microbiol (2009) 0.95

How stands the Tree of Life a century and a half after The Origin? Biol Direct (2011) 0.95

Archaeal Clusters of Orthologous Genes (arCOGs): An Update and Application for Analysis of Shared Features between Thermococcales, Methanococcales, and Methanobacteriales. Life (Basel) (2015) 0.95

The tree of genomes: an empirical comparison of genome-phylogeny reconstruction methods. BMC Evol Biol (2008) 0.93

A novel taxonomic marker that discriminates between morphologically complex actinomycetes. Open Biol (2013) 0.93

On the need for widespread horizontal gene transfers under genome size constraint. Biol Direct (2009) 0.92

Gene and genome trees conflict at many levels. Philos Trans R Soc Lond B Biol Sci (2009) 0.92

BranchClust: a phylogenetic algorithm for selecting gene families. BMC Bioinformatics (2007) 0.92

Reconstructing the fungal tree of life using phylogenomics and a preliminary investigation of the distribution of yeast prion-like proteins in the fungal kingdom. J Mol Evol (2011) 0.90

Horizontal gene transfer: essentiality and evolvability in prokaryotes, and roles in evolutionary transitions. F1000Res (2016) 0.90

The advantages and disadvantages of horizontal gene transfer and the emergence of the first species. Biol Direct (2011) 0.90

Of woods and webs: possible alternatives to the tree of life for studying genomic fluidity in E. coli. Biol Direct (2011) 0.90

Pandoraviruses are highly derived phycodnaviruses. Biol Direct (2013) 0.89

A late origin of the extant eukaryotic diversity: divergence time estimates using rare genomic changes. Biol Direct (2011) 0.89

Molecular Data are Transforming Hypotheses on the Origin and Diversification of Eukaryotes. Bioscience (2009) 0.89

Bacterial gene import and mesophilic adaptation in archaea. Nat Rev Microbiol (2015) 0.89

Darwin's goldmine is still open: variation and selection run the world. Front Cell Infect Microbiol (2012) 0.88

A natural barrier to lateral gene transfer from prokaryotes to eukaryotes revealed from genomes: the 70 % rule. BMC Biol (2016) 0.86

The phylogenetic forest and the quest for the elusive tree of life. Cold Spring Harb Symp Quant Biol (2009) 0.85

Minimization of extracellular space as a driving force in prokaryote association and the origin of eukaryotes. Biol Direct (2014) 0.85

The eocyte hypothesis and the origin of eukaryotic cells. Proc Natl Acad Sci U S A (2008) 0.85

Which Phylogenetic Networks are Merely Trees with Additional Arcs? Syst Biol (2015) 0.84

Carl Woese's vision of cellular evolution and the domains of life. RNA Biol (2014) 0.84

Rhizome of life, catastrophes, sequence exchanges, gene creations, and giant viruses: how microbial genomics challenges Darwin. Front Cell Infect Microbiol (2012) 0.83

Evaluating phylogenetic congruence in the post-genomic era. Genome Biol Evol (2011) 0.83

Recovering the treelike trend of evolution despite extensive lateral genetic transfer: a probabilistic analysis. J Comput Biol (2013) 0.83

Archaea: the first domain of diversified life. Archaea (2014) 0.82

What Is Speciation? PLoS Genet (2016) 0.82

The bacterial pangenome as a new tool for analysing pathogenic bacteria. New Microbes New Infect (2015) 0.81

Protein based molecular markers provide reliable means to understand prokaryotic phylogeny and support Darwinian mode of evolution. Front Cell Infect Microbiol (2012) 0.80

Towards a processual microbial ontology. Biol Philos (2012) 0.80

The Turbulent Network Dynamics of Microbial Evolution and the Statistical Tree of Life. J Mol Evol (2015) 0.80

Save the tree of life or get lost in the woods. Biol Direct (2010) 0.79

Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria. Genome Biol Evol (2015) 0.79

Primal eukaryogenesis: on the communal nature of precellular States, ancestral to modern life. Life (Basel) (2012) 0.78

Horizontal gene flow from Eubacteria to Archaebacteria and what it means for our understanding of eukaryogenesis. Philos Trans R Soc Lond B Biol Sci (2015) 0.78

Phylogenomics-based reconstruction of protozoan species tree. Evol Bioinform Online (2011) 0.78

Proteome-wide analysis of functional divergence in bacteria: exploring a host of ecological adaptations. PLoS One (2012) 0.78

Bayesian analysis of congruence of core genes in Prochlorococcus and Synechococcus and implications on horizontal gene transfer. PLoS One (2014) 0.78

One step beyond a ribosome: The ancient anaerobic core. Biochim Biophys Acta (2016) 0.78

Evolution of protein families: is it possible to distinguish between domains of life? Gene (2007) 0.77

Complex patterns of gene fission in the eukaryotic folate biosynthesis pathway. Genome Biol Evol (2014) 0.76

Modularized evolution in archaeal methanogens phylogenetic forest. Genome Biol Evol (2014) 0.76

Assessing parallel gene histories in viral genomes. BMC Evol Biol (2016) 0.76

Recent advances in the expression, evolution, and dynamics of prokaryotic genomes. J Bacteriol (2007) 0.76

Molecular musings in microbial ecology and evolution. Biol Direct (2011) 0.75

Ordered orthology as a tool in prokaryotic evolutionary inference. Mob Genet Elements (2015) 0.75

Recapitulating phylogenies using k-mers: from trees to networks. F1000Res (2016) 0.75

Comparative Genomics of Burkholderia singularis sp. nov., a Low G+C Content, Free-Living Bacterium That Defies Taxonomic Dissection of the Genus Burkholderia. Front Microbiol (2017) 0.75

Cultural macroevolution matters. Proc Natl Acad Sci U S A (2017) 0.75

Articles cited by this

Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. Proc Natl Acad Sci U S A (1990) 50.63

NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res (2005) 37.39

Application of phylogenetic networks in evolutionary studies. Mol Biol Evol (2005) 31.72

Toward automatic reconstruction of a highly resolved tree of life. Science (2006) 14.96

Phylogenetic classification and the universal tree. Science (1999) 14.28

Evolutionary relationship of archaebacteria, eubacteria, and eukaryotes inferred from phylogenetic trees of duplicated genes. Proc Natl Acad Sci U S A (1989) 8.45

Endosymbiotic gene transfer: organelle genomes forge eukaryotic chromosomes. Nat Rev Genet (2004) 5.51

Horizontal gene transfer, genome innovation and evolution. Nat Rev Microbiol (2005) 5.21

Eukaryotic evolution, changes and challenges. Nature (2006) 5.10

Evolution of the vacuolar H+-ATPase: implications for the origin of eukaryotes. Proc Natl Acad Sci U S A (1989) 4.92

Genomes in flux: the evolution of archaeal and proteobacterial gene content. Genome Res (2002) 4.85

Algorithms for computing parsimonious evolutionary scenarios for genome evolution, the last universal common ancestor and dominance of horizontal gene transfer in the evolution of prokaryotes. BMC Evol Biol (2003) 4.70

The universal ancestor. Proc Natl Acad Sci U S A (1998) 4.51

On the origin of mitosing cells J Theor Biol (1967) 4.36

Adaptive evolution of bacterial metabolic networks by horizontal gene transfer. Nat Genet (2005) 4.19

Interpreting the universal phylogenetic tree. Proc Natl Acad Sci U S A (2000) 4.09

Determining divergence times with a protein clock: update and reevaluation. Proc Natl Acad Sci U S A (1997) 4.05

Time for a change. Nature (2006) 3.92

The phagotrophic origin of eukaryotes and phylogenetic classification of Protozoa. Int J Syst Evol Microbiol (2002) 3.84

Genomic evidence for two functionally distinct gene classes. Proc Natl Acad Sci U S A (1998) 3.72

Phylogenetics and the cohesion of bacterial genomes. Science (2003) 3.61

On the prokaryotic nature of red algal chloroplasts. Proc Natl Acad Sci U S A (1975) 3.52

On the evolution of cells. Proc Natl Acad Sci U S A (2002) 3.47

Evolutionary origins of genomic repertoires in bacteria. PLoS Biol (2005) 3.43

Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation. Nature (2003) 3.38

The ring of life provides evidence for a genome fusion origin of eukaryotes. Nature (2004) 3.35

Horizontal gene transfer: a critical view. Proc Natl Acad Sci U S A (2003) 3.27

Introns and the origin of nucleus-cytosol compartmentalization. Nature (2006) 3.16

A mitochondrial remnant in the microsporidian Trachipleistophora hominis. Nature (2002) 2.98

Protein phylogenies and signature sequences: A reappraisal of evolutionary relationships among archaebacteria, eubacteria, and eukaryotes. Microbiol Mol Biol Rev (1998) 2.96

Testing the exon theory of genes: the evidence from protein structure. Science (1994) 2.71

Genomics and the irreducible nature of eukaryote cells. Science (2006) 2.60

A genome phylogeny for mitochondria among alpha-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes. Mol Biol Evol (2004) 2.32

The net of life: reconstructing the microbial phylogenetic network. Genome Res (2005) 2.31

Ancient horizontal gene transfer. Nat Rev Genet (2003) 2.29

Evolution of intraflagellar transport from coated vesicles and autogenous origin of the eukaryotic cilium. Bioessays (2006) 2.26

The hydrogenosome. J Gen Microbiol (1993) 2.23

The biology of intron gain and loss. Trends Genet (2005) 2.07

How big is the iceberg of which organellar genes in nuclear genomes are but the tip? Philos Trans R Soc Lond B Biol Sci (2003) 1.95

The cobweb of life revealed by genome-scale estimates of horizontal gene transfer. PLoS Biol (2005) 1.79

The origin of eukaryotic and archaebacterial cells. Ann N Y Acad Sci (1987) 1.78

The mitosome, a novel organelle related to mitochondria in the amitochondrial parasite Entamoeba histolytica. Mol Microbiol (1999) 1.75

The simultaneous symbiotic origin of mitochondria, chloroplasts, and microbodies. Ann N Y Acad Sci (1987) 1.70

Using consensus networks to visualize contradictory evidence for species phylogeny. Mol Biol Evol (2004) 1.65

Cell evolution and Earth history: stasis and revolution. Philos Trans R Soc Lond B Biol Sci (2006) 1.59

Relics from the RNA world. J Mol Evol (1998) 1.57

Phylogenetic super-networks from partial trees. IEEE/ACM Trans Comput Biol Bioinform (2006) 1.55

Origin and evolution of the peroxisomal proteome. Biol Direct (2006) 1.55

Where is the root of the universal tree of life? Bioessays (1999) 1.53

Visualizing and assessing phylogenetic congruence of core gene sets: a case study of the gamma-proteobacteria. Mol Biol Evol (2006) 1.50

Was the nucleus the first endosymbiont? Proc Natl Acad Sci U S A (1994) 1.41

Mitochondrion-derived organelles in protists and fungi. Int Rev Cytol (2005) 1.36

The origin of nuclei and of eukaryotic cells. Nature (1975) 1.35

Early evolution: prokaryotes, the new kids on the block. Bioessays (1999) 1.27

The chimeric eukaryote: origin of the nucleus from the karyomastigont in amitochondriate protists. Proc Natl Acad Sci U S A (2000) 1.23

Patterns of bacterial gene movement. Mol Biol Evol (2004) 1.20

The origin of eukaryotes is suggested as the symbiosis of pyrococcus into gamma-proteobacteria by phylogenetic tree based on gene content. J Mol Evol (2004) 1.10

The nature of the last universal common ancestor. Curr Opin Genet Dev (1999) 1.05

Archaebacteria (Archaea) and the origin of the eukaryotic nucleus. Curr Opin Microbiol (2005) 1.00

Thermoreduction, a hypothesis for the origin of prokaryotes. C R Acad Sci III (1995) 0.98

Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Improved consensus network techniques for genome-scale phylogeny. Mol Biol Evol (2005) 0.92

Fun with genealogy. Proc Natl Acad Sci U S A (1997) 0.80

Articles by these authors

(truncated to the top 100)

Reading the entrails of chickens: molecular timescales of evolution and the illusion of precision. Trends Genet (2004) 17.22

Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements. PLoS Biol (2004) 7.95

Endosymbiotic gene transfer: organelle genomes forge eukaryotic chromosomes. Nat Rev Genet (2004) 5.51

Eukaryotic evolution, changes and challenges. Nature (2006) 5.10

The energetics of genome complexity. Nature (2010) 4.58

Genetics and geography of wild cereal domestication in the near east. Nat Rev Genet (2002) 3.30

Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution. Proc Natl Acad Sci U S A (2008) 2.97

Molecular poltergeists: mitochondrial DNA copies (numts) in sequenced nuclear genomes. PLoS Genet (2010) 2.70

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes". Blood (2008) 2.50

The evolutionary root of flowering plants. Syst Biol (2012) 2.46

A genome phylogeny for mitochondria among alpha-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes. Mol Biol Evol (2004) 2.32

Prokaryotic evolution and the tree of life are two different things. Biol Direct (2009) 2.17

On the origin of genomes and cells within inorganic compartments. Trends Genet (2005) 2.04

Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution. Proc Natl Acad Sci U S A (2007) 1.96

The rocky roots of the acetyl-CoA pathway. Trends Biochem Sci (2004) 1.92

Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants (2004) 1.84

Acceleration of genomic evolution caused by enhanced mutation rate in endocellular symbionts. Proc Natl Acad Sci U S A (2002) 1.79

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics. Clin Immunol (2009) 1.73

Genes of cyanobacterial origin in plant nuclear genomes point to a heterocyst-forming plastid ancestor. Mol Biol Evol (2008) 1.62

Directed networks reveal genomic barriers and DNA repair bypasses to lateral gene transfer among prokaryotes. Genome Res (2011) 1.58

HIV vaccine development by computer assisted design: the GAIA vaccine. Vaccine (2005) 1.56

Radiofrequency ablation for persistent atrial fibrillation in patients with advanced heart failure and severe left ventricular systolic dysfunction: a randomised controlled trial. Heart (2010) 1.54

Mitochondria as we don't know them. Trends Biochem Sci (2002) 1.49

Haplotype structure at seven barley genes: relevance to gene pool bottlenecks, phylogeny of ear type and site of barley domestication. Mol Genet Genomics (2006) 1.49

Testing hypotheses without considering predictions. Bioessays (2007) 1.48

A unique set of 11,008 onion expressed sequence tags reveals expressed sequence and genomic differences between the monocot orders Asparagales and Poales. Plant Cell (2003) 1.46

Immuno-informatics: Mining genomes for vaccine components. Immunol Cell Biol (2002) 1.46

Utility of the neutrophil to lymphocyte ratio in predicting long-term outcomes in acute decompensated heart failure. Am J Cardiol (2011) 1.44

Networks of gene sharing among 329 proteobacterial genomes reveal differences in lateral gene transfer frequency at different phylogenetic depths. Mol Biol Evol (2010) 1.42

A proteomic survey of Chlamydomonas reinhardtii mitochondria sheds new light on the metabolic plasticity of the organelle and on the nature of the alpha-proteobacterial mitochondrial ancestor. Mol Biol Evol (2009) 1.41

Prognosis of endodontically treated teeth? Point. Quintessence Int (2003) 1.39

Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design. Hum Vaccin Immunother (2013) 1.38

Single eubacterial origin of eukaryotic sulfide:quinone oxidoreductase, a mitochondrial enzyme conserved from the early evolution of eukaryotes during anoxic and sulfidic times. Mol Biol Evol (2003) 1.37

How did LUCA make a living? Chemiosmosis in the origin of life. Bioessays (2010) 1.33

A positive definition of prokaryotes. Nature (2006) 1.29

Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides. Proc Natl Acad Sci U S A (2004) 1.28

Mutational decay and age of chloroplast and mitochondrial genomes transferred recently to angiosperm nuclear chromosomes. Plant Physiol (2005) 1.27

Evolutionary biology: essence of mitochondria. Nature (2003) 1.25

The origin of mitochondria in light of a fluid prokaryotic chromosome model. Biol Lett (2007) 1.25

Transcriptomic evidence that longevity of acquired plastids in the photosynthetic slugs Elysia timida and Plakobranchus ocellatus does not entail lateral transfer of algal nuclear genes. Mol Biol Evol (2010) 1.24

Pyruvate formate-lyase and a novel route of eukaryotic ATP synthesis in Chlamydomonas mitochondria. J Biol Chem (2006) 1.22

Networks uncover hidden lexical borrowing in Indo-European language evolution. Proc Biol Sci (2010) 1.18

Getting a better picture of microbial evolution en route to a network of genomes. Philos Trans R Soc Lond B Biol Sci (2009) 1.15

Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4(+) T cells against the swine-origin H1N1 influenza virus. Vaccine (2011) 1.14

166Ho-DOTMP radiation-absorbed dose estimation for skeletal targeted radiotherapy. J Nucl Med (2006) 1.14

Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants. A case study of endosymbiotic gene transfer. Eur J Biochem (2002) 1.12

Acetate formation in the energy metabolism of parasitic helminths and protists. Int J Parasitol (2010) 1.11

Energy metabolism among eukaryotic anaerobes in light of Proterozoic ocean chemistry. Philos Trans R Soc Lond B Biol Sci (2008) 1.11

HelicoVax: epitope-based therapeutic Helicobacter pylori vaccination in a mouse model. Vaccine (2011) 1.09

Evolutionary biology: out of thin air. Nature (2007) 1.09

Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach. Vaccine (2003) 1.07

Utility of FDG-PET/CT in follow-up of children treated for Hodgkin and non-Hodgkin lymphoma. J Pediatr Hematol Oncol (2006) 1.07

Epitope-based vaccination against pneumonic tularemia. Vaccine (2009) 1.05

Difficulties in testing for covarion-like properties of sequences under the confounding influence of changing proportions of variable sites. Mol Biol Evol (2008) 1.04

The difference between organelles and endosymbionts. Curr Biol (2006) 1.03

Genome networks root the tree of life between prokaryotic domains. Genome Biol Evol (2010) 1.02

Carvedilol alone or in combination with digoxin for the management of atrial fibrillation in patients with heart failure? J Am Coll Cardiol (2003) 1.02

Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice. Curr Mol Med (2007) 1.02

Sulfide : quinone oxidoreductase (SQR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity. FEBS J (2008) 1.00

Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine. Methods (2004) 1.00

Making vaccines "on demand": a potential solution for emerging pathogens and biodefense? Hum Vaccin Immunother (2013) 1.00

Novel function of complement C3d as an autologous helper T-cell target. Immunol Cell Biol (2008) 0.99

Acetate:succinate CoA-transferase in the hydrogenosomes of Trichomonas vaginalis: identification and characterization. J Biol Chem (2007) 0.98

Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis. J Biol Chem (2004) 0.98

Interspecific evolution: microbial symbiosis, endosymbiosis and gene transfer. Environ Microbiol (2003) 0.97

ERAD components in organisms with complex red plastids suggest recruitment of a preexisting protein transport pathway for the periplastid membrane. Genome Biol Evol (2010) 0.97

Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV. Vaccine (2007) 0.96

Euglena gracilis rhodoquinone:ubiquinone ratio and mitochondrial proteome differ under aerobic and anaerobic conditions. J Biol Chem (2004) 0.96

Ascorbate blocks endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation in the bovine ciliary vascular bed and rat mesentery. Br J Pharmacol (2002) 0.96

Bifunctional aldehyde/alcohol dehydrogenase (ADHE) in chlorophyte algal mitochondria. Plant Mol Biol (2003) 0.94

The evolution of eukaryotes. Science (2007) 0.93

VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone. Vaccine (2010) 0.92

Dietary protein intake impacts human skeletal muscle protein fractional synthetic rates after endurance exercise. Am J Physiol Endocrinol Metab (2005) 0.92

A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM). J Biomed Biotechnol (2010) 0.92

Euglena gracilis ribonucleotide reductase: the eukaryote class II enzyme and the possible antiquity of eukaryote B12 dependence. J Biol Chem (2005) 0.91

Thyrotropin receptor epitopes and their relation to histocompatibility leukocyte antigen-DR molecules in Graves' disease. J Clin Endocrinol Metab (2006) 0.91

Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics. Expert Rev Clin Pharmacol (2013) 0.91

The neglected genome. EMBO Rep (2012) 0.90

The effect of progesterone on myometrial contractility, potassium channels, and tocolytic efficacy. Reprod Sci (2009) 0.89

Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes. J Diabetes Res (2013) 0.89

A novel prokaryotic trans-2-enoyl-CoA reductase from the spirochete Treponema denticola. FEBS Lett (2007) 0.89

Evolutionary dynamics of introns in plastid-derived genes in plants: saturation nearly reached but slow intron gain continues. Mol Biol Evol (2007) 0.89

Evolutionary deimmunization: an ancillary mechanism for self-tolerance? Cell Immunol (2007) 0.89

Evolutionary biology: Early evolution comes full circle. Nature (2004) 0.89

Differential effects of ascorbate on endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation in the bovine ciliary vascular bed and coronary artery. Br J Pharmacol (2003) 0.88

Protein import into hydrogenosomes of Trichomonas vaginalis involves both N-terminal and internal targeting signals: a case study of thioredoxin reductases. Eukaryot Cell (2008) 0.88

Immune response of mice transgenic for human histocompatibility leukocyte Antigen-DR to human thyrotropin receptor-extracellular domain. Thyroid (2009) 0.87

Genome history in the symbiotic hybrid Euglena gracilis. Gene (2007) 0.87

Sodium nitrite mitigates ventilator-induced lung injury in rats. Anesthesiology (2012) 0.87

Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease. Hum Vaccin Immunother (2012) 0.87

An audit of outcome in intravascular transfusions using the intrahepatic portion of the fetal umbilical vein compared to cordocentesis. Fetal Diagn Ther (2006) 0.87

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses. PLoS One (2012) 0.87

Effects of a cementing technique in addition to luting agent on the uniaxial retention force of a single-tooth implant-supported restoration: an in vitro study. Int J Oral Maxillofac Implants (2011) 0.86

From immunome to vaccine: epitope mapping and vaccine design tools. Novartis Found Symp (2003) 0.85

Networks of lexical borrowing and lateral gene transfer in language and genome evolution. Bioessays (2013) 0.85

Variability of wax ester fermentation in natural and bleached Euglena gracilis Strains in response to oxygen and the elongase inhibitor flufenacet. J Eukaryot Microbiol (2009) 0.84

Rate and polarity of gene fusion and fission in Oryza sativa and Arabidopsis thaliana. Mol Biol Evol (2006) 0.84

Supertrees and symbiosis in eukaryote genome evolution. Trends Microbiol (2007) 0.83

Identification of prokaryotic homologues indicates an endosymbiotic origin for the alternative oxidases of mitochondria (AOX) and chloroplasts (PTOX). Gene (2004) 0.83

Restoration of disk height through non-surgical spinal decompression is associated with decreased discogenic low back pain: a retrospective cohort study. BMC Musculoskelet Disord (2010) 0.82