Published in J Lipid Res on February 01, 2004
Quantification of the clinical modifiers impacting high-density lipoprotein cholesterol in the community: Personalized Medicine Research Project. Prev Cardiol (2010) 1.14
A genome-wide linkage scan identifies multiple chromosomal regions influencing serum lipid levels in the population on the Samoan islands. J Lipid Res (2008) 1.11
Comparison of linkage disequilibrium patterns between the HapMap CEPH samples and a family-based cohort of Northern European descent. Genomics (2006) 1.08
Genetic architecture of lipid traits changes over time and differs by race: Princeton Lipid Follow-up Study. J Lipid Res (2014) 1.02
Genome-wide linkage analysis of population variation in high-density lipoprotein cholesterol. Hum Genet (2006) 0.92
INSIG1 influences obesity-related hypertriglyceridemia in humans. J Lipid Res (2009) 0.92
Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index. Pharmacogenomics (2008) 0.91
Univariate and bivariate linkage analysis identifies pleiotropic loci underlying lipid levels and type 2 diabetes risk. Ann Hum Genet (2010) 0.89
Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels. Physiol Genomics (2010) 0.81
Detection of quantitative trait loci affecting serum cholesterol, LDL, HDL, and triglyceride in pigs. BMC Genet (2011) 0.81
Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arrays. Genomics Proteomics Bioinformatics (2007) 0.79
Accounting for a quantitative trait locus for plasma triglyceride levels: utilization of variants in multiple genes. PLoS One (2012) 0.78
A novel method, the Variant Impact On Linkage Effect Test (VIOLET), leads to improved identification of causal variants in linkage regions. Eur J Hum Genet (2013) 0.75
Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97
Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet (1994) 10.58
Multipoint analysis of human quantitative genetic variation. Am J Hum Genet (1990) 9.09
Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am J Hum Genet (1993) 8.05
Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet (1997) 7.78
Extensions to multivariate normal models for pedigree analysis. Ann Hum Genet (1982) 7.07
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev (2002) 6.05
Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I. Circulation (2003) 4.61
Multipoint interval mapping of quantitative trait loci, using sib pairs. Am J Hum Genet (1995) 4.29
"Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Arteriosclerosis (1990) 4.01
Regional adiposity and morbidity. Physiol Rev (1994) 3.85
An endothelial receptor for oxidized low-density lipoprotein. Nature (1997) 3.76
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci U S A (2000) 3.44
Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab (2000) 3.42
Multipoint oligogenic linkage analysis of quantitative traits. Genet Epidemiol (1997) 3.38
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. J Clin Invest (1998) 3.06
Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA (1988) 3.04
A gene for hereditary pancreatitis maps to chromosome 7q35. Gastroenterology (1996) 2.86
Variance component methods for detecting complex trait loci. Adv Genet (2001) 2.78
Nitric oxide as a signaling molecule in the vascular system: an overview. J Cardiovasc Pharmacol (1999) 2.66
Sibling-based tests of linkage and association for quantitative traits. Am J Hum Genet (1999) 2.64
Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev (2003) 2.58
Robust LOD scores for variance component-based linkage analysis. Genet Epidemiol (2000) 2.10
Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study. Hum Mol Genet (2000) 1.94
Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol (2001) 1.89
LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. Pharmacol Ther (2002) 1.74
Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families. Am J Hum Genet (2002) 1.45
Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis (1994) 1.40
Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Diabetes Metab Rev (1989) 1.37
Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease. Clin Chem (2003) 1.31
Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures. Arterioscler Thromb Vasc Biol (1996) 1.30
Central role of the adipocyte in the metabolic syndrome. J Investig Med (2001) 1.26
Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7. Am J Hum Genet (1996) 1.22
A major susceptibility locus influencing plasma triglyceride concentrations is located on chromosome 15q in Mexican Americans. Am J Hum Genet (2000) 1.22
Endothelial nitric oxide synthase polymorphisms are associated with type 2 diabetes and the insulin resistance syndrome. Diabetes (2003) 1.15
Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. Proc Natl Acad Sci U S A (1996) 1.13
Polymorphisms in endothelial nitric oxide synthase and atherogenesis: John French Lecture 2000. Atherosclerosis (2001) 1.12
A major locus influencing plasma high-density lipoprotein cholesterol levels in the San Antonio Family Heart Study. Segregation and linkage analyses. Arterioscler Thromb Vasc Biol (1995) 1.04
Genetic aspects of susceptibility to obesity and related dyslipidemias. Mol Cell Biochem (1992) 0.98
Genome scan for quantitative trait loci linked to high-density lipoprotein cholesterol: The NHLBI Family Heart Study. Arterioscler Thromb Vasc Biol (2001) 0.97
Circulating oxidized low-density lipoprotein (LDL) is associated with risk factors of the metabolic syndrome and LDL size in clinically healthy 58-year-old men (AIR study). J Intern Med (2002) 0.95
Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease. Arterioscler Thromb Vasc Biol (2001) 0.94
Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension resistant to conventional therapy. Biochem Biophys Res Commun (2001) 0.93
Obesity, metabolic syndrome X, and inflammation. Nutrition (2002) 0.92
Hyperinsulinemia, upper body adiposity, and cardiovascular risk factors in non-diabetics. Metabolism (1988) 0.91
Association of (-)786T-C mutation of endothelial nitric oxide synthase gene with insulin resistance. Diabetologia (2002) 0.91
Metabolic complications of visceral obesity: contribution to the aetiology of type 2 diabetes and implications for prevention and treatment. Diabete Metab (1995) 0.90
Apolipoprotein B mRNA editing: a key controlling element targeting fats to proper tissue. Ann Med (1993) 0.84
Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy. Am J Med Genet (2001) 0.83
Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A. Int J Obes Relat Metab Disord (2000) 0.81
Evidence for a major gene accounting for mild elevation in LDL cholesterol: the NHLBI Family Heart Study. Ann Hum Genet (1999) 0.77
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
Mammographic density and the risk and detection of breast cancer. N Engl J Med (2007) 14.32
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol (2013) 5.24
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation (2013) 5.02
The Rat Genome Database, update 2007--easing the path from disease to data and back again. Nucleic Acids Res (2006) 4.80
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage (2009) 3.66
Breast tissue composition and susceptibility to breast cancer. J Natl Cancer Inst (2010) 3.39
A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet (2002) 3.19
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Mammographic density and breast cancer risk: current understanding and future prospects. Breast Cancer Res (2011) 2.86
Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am J Psychiatry (2007) 2.84
Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Mol Genet (2002) 2.71
Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet (2010) 2.47
Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Res (2002) 2.45
Body size, mammographic density, and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2006) 2.44
Rat genetics: attaching physiology and pharmacology to the genome. Nat Rev Genet (2002) 2.44
Genetic and environmental factors influencing the human factor H plasma levels. Immunogenetics (2004) 2.43
Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function. Hum Brain Mapp (2007) 2.36
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum Mol Genet (2002) 2.27
Hypoplastic left heart syndrome is heritable. J Am Coll Cardiol (2007) 2.24
High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry (2011) 2.23
Bicuspid aortic valve is heritable. J Am Coll Cardiol (2004) 2.18
Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican-americans. Diabetes (2002) 2.06
Physiogenomic resources for rat models of heart, lung and blood disorders. Nat Genet (2006) 2.05
Genetic variation in selenoprotein S influences inflammatory response. Nat Genet (2005) 2.00
Viva la Familia Study: genetic and environmental contributions to childhood obesity and its comorbidities in the Hispanic population. Am J Clin Nutr (2006) 1.99
The quantitative trait linkage disequilibrium test: a more powerful alternative to the quantitative transmission disequilibrium test for use in the absence of population stratification. BMC Genet (2005) 1.98
Estimating the additive genetic effect of the X chromosome. Genet Epidemiol (2005) 1.95
Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays. Genome Biol (2003) 1.94
Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes (2009) 1.91
Mammographic density as a surrogate marker for the effects of hormone therapy on risk of breast cancer. Cancer Epidemiol Biomarkers Prev (2006) 1.91
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
Hypoplastic left heart syndrome links to chromosomes 10q and 6q and is genetically related to bicuspid aortic valve. J Am Coll Cardiol (2009) 1.88
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. J Immunol (2010) 1.85
Heritability of age at menarche in girls from the Fels Longitudinal Study. Am J Phys Anthropol (2005) 1.81
Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT project. Thromb Haemost (2003) 1.80
MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers. J Allergy Clin Immunol (2012) 1.79
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage (2013) 1.78
Common variants in ZNF365 are associated with both mammographic density and breast cancer risk. Nat Genet (2011) 1.77
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol (2010) 1.74
Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study. Diabetes (2005) 1.72
Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population. J Clin Endocrinol Metab (2009) 1.72
Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study. Atherosclerosis (2007) 1.68
Long-term changes in adiposity and glycemic control are associated with past adenovirus infection. Diabetes Care (2012) 1.63
Amygdalar and hippocampal substrates of anxious temperament differ in their heritability. Nature (2010) 1.63
A novel pathway to the manifestations of metabolic syndrome. Obes Res (2004) 1.62
On the genetic architecture of cortical folding and brain volume in primates. Neuroimage (2010) 1.62
A genomewide search finds major susceptibility loci for gallbladder disease on chromosome 1 in Mexican Americans. Am J Hum Genet (2006) 1.59
Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res (2012) 1.58
Risk factors for aortic valve disease in bicuspid aortic valve: a family-based study. Am J Med Genet A (2011) 1.55
Metabolic and behavioral predictors of weight gain in Hispanic children: the Viva la Familia Study. Am J Clin Nutr (2007) 1.53
A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. Diabetes (2005) 1.52
Genetic variants in SCN5A promoter are associated with arrhythmia phenotype severity in patients with heterozygous loss-of-function mutation. Heart Rhythm (2012) 1.51
Plasma lipidomic profile signature of hypertension in Mexican American families: specific role of diacylglycerols. Hypertension (2013) 1.51
Adjudicating neurocognitive endophenotypes for schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2007) 1.48
A quantitative trait locus influencing free plasma protein S levels on human chromosome 1q: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) project. Arterioscler Thromb Vasc Biol (2003) 1.48
Heritability of brain volume, surface area and shape: an MRI study in an extended pedigree of baboons. Hum Brain Mapp (2007) 1.47
Quality assessment of buccal versus blood genomic DNA using the Affymetrix 500 K GeneChip. BMC Genet (2007) 1.47
A genome search for genetic determinants that influence plasma fibrinogen levels. Arterioscler Thromb Vasc Biol (2005) 1.47
Quantitative trait nucleotide analysis using Bayesian model selection. 2005. Hum Biol (2009) 1.46
Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons. Proc Natl Acad Sci U S A (2009) 1.45
Variable expression of neurofibromatosis 1 in monozygotic twins. Am J Med Genet A (2011) 1.45
A quantitative trait locus on chromosome 18q for physical activity and dietary intake in Hispanic children. Obesity (Silver Spring) (2006) 1.44
Variance component methods for analysis of complex phenotypes. Cold Spring Harb Protoc (2010) 1.44
The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus. 2005. Hum Biol (2009) 1.43
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome (2012) 1.43
The functional connectivity of the human caudate: an application of meta-analytic connectivity modeling with behavioral filtering. Neuroimage (2011) 1.41
ZoomQuant: an application for the quantitation of stable isotope labeled peptides. J Am Soc Mass Spectrom (2005) 1.41
Quantitative loci regulating plasma levels of gamma glutamyl transferase and albumin and their genetic correlations with cardiovascular risk factors. Exp Biol Med (Maywood) (2009) 1.39
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet (2013) 1.39
Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol (2008) 1.37
Impact of genomics on research in the rat. Genome Res (2005) 1.37
High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders. J Allergy Clin Immunol (2013) 1.35
Plasma lipid profiling in a large population-based cohort. J Lipid Res (2013) 1.35
The baboon as a nonhuman primate model for the study of the genetics of obesity. Obes Res (2003) 1.34
Physiological and molecular determinants of insulin action in the baboon. Diabetes (2008) 1.34
Linkage and segregation analysis of black and brindle coat color in domestic dogs. Genetics (2007) 1.32
Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) (2007) 1.32
Gallstones: genetics versus environment. Ann Surg (2002) 1.32