Published in Am J Physiol Heart Circ Physiol on November 03, 2006
Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci (2010) 2.24
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. Circulation (2009) 2.03
The role of liver-derived insulin-like growth factor-I. Endocr Rev (2009) 1.87
Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res (2008) 1.75
The intersection between aging and cardiovascular disease. Circ Res (2012) 1.61
Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol (2008) 1.55
Mitochondria and cardiovascular aging. Circ Res (2012) 1.46
The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. J Gerontol A Biol Sci Med Sci (2012) 1.14
AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction. Aging Cell (2010) 1.14
Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction. J Mol Cell Cardiol (2010) 1.12
Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med (2012) 1.12
Deficiency of insulin-like growth factor 1 reduces sensitivity to aging-associated cardiomyocyte dysfunction. Rejuvenation Res (2008) 1.06
Chronic treatment with insulin-like growth factor I enhances myocyte contraction by upregulation of Akt-SERCA2a signaling pathway. Am J Physiol Heart Circ Physiol (2008) 1.05
Hydrogen peroxide-mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart. J Am Heart Assoc (2013) 1.04
Effects of myostatin deletion in aging mice. Aging Cell (2009) 1.02
Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3beta, and PTEN. Free Radic Biol Med (2010) 1.01
Modulation of sarcoplasmic reticulum Ca(2+) cycling in systolic and diastolic heart failure associated with aging. Heart Fail Rev (2010) 0.98
Electromechanical and structural alterations in the aging rabbit heart and aorta. Am J Physiol Heart Circ Physiol (2012) 0.97
Growth factors, nutrient signaling, and cardiovascular aging. Circ Res (2012) 0.91
Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function. Free Radic Biol Med (2014) 0.86
Effects of short-term treadmill exercise training or growth hormone supplementation on diastolic function and exercise tolerance in old rats. J Gerontol A Biol Sci Med Sci (2008) 0.86
Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats. J Transl Med (2011) 0.84
IGF-IR in neuroprotection and brain tumors. Front Biosci (Landmark Ed) (2009) 0.83
The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase. Exp Physiol (2009) 0.83
Oxidative stress and autonomic dysregulation contribute to the acute time-dependent myocardial depressant effect of ethanol in conscious female rats. Alcohol Clin Exp Res (2014) 0.82
NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? Clin Sci (Lond) (2016) 0.82
Activation of proteasome by insulin-like growth factor-I may enhance clearance of oxidized proteins in the brain. Mech Ageing Dev (2009) 0.79
Predicting the future with stem cells. Circulation (2013) 0.79
A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci (2013) 0.76
Cardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target? Curr Pharm Des (2013) 0.75
Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation. Aging Cell (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell (2003) 18.09
Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med (2011) 13.18
Concern Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet (2011) 11.45
Chimerism of the transplanted heart. N Engl J Med (2002) 8.69
Human cardiac stem cells. Proc Natl Acad Sci U S A (2007) 7.76
Evidence for human lung stem cells. N Engl J Med (2011) 5.67
Nosocomial transmission of human granulocytic anaplasmosis in China. JAMA (2008) 5.01
Stem cell niches in the adult mouse heart. Proc Natl Acad Sci U S A (2006) 4.58
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc Natl Acad Sci U S A (2005) 4.13
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression. Circ Res (2004) 4.13
Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival. Circ Res (2005) 3.93
Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure. Proc Natl Acad Sci U S A (2005) 3.93
An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China. Virol J (2010) 3.90
Person-to-person transmission of severe fever with thrombocytopenia syndrome virus. Vector Borne Zoonotic Dis (2011) 3.73
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function. Proc Natl Acad Sci U S A (2005) 3.64
Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation (2010) 3.42
Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res (2004) 3.39
Cardiac stem cells and mechanisms of myocardial regeneration. Physiol Rev (2005) 3.30
Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. Cell (2003) 3.19
Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function. Circ Res (2008) 3.07
Bone marrow cells adopt the cardiomyogenic fate in vivo. Proc Natl Acad Sci U S A (2007) 3.06
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc Natl Acad Sci U S A (2003) 2.95
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res (2004) 2.91
Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance. Circulation (2012) 2.83
Cardiomyogenesis in the adult human heart. Circ Res (2010) 2.79
Myocyte turnover in the aging human heart. Circ Res (2010) 2.77
Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology. Circ Res (2011) 2.76
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A (2006) 2.75
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene. Circ Res (2006) 2.71
Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol (2006) 2.68
Chronic kidney disease is associated with the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study. Circulation (2011) 2.64
Clonality of mouse and human cardiomyogenesis in vivo. Proc Natl Acad Sci U S A (2009) 2.60
Life and death of cardiac stem cells: a paradigm shift in cardiac biology. Circulation (2006) 2.56
Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ Res (2003) 2.45
Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med (2007) 2.39
Human cardiac stem cell differentiation is regulated by a mircrine mechanism. Circulation (2011) 2.38
Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties. Circ Res (2007) 2.38
PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury. J Clin Invest (2005) 2.36
Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population. Circ Res (2006) 2.34
Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation. Circ Res (2005) 2.32
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ Res (2008) 2.31
Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction. Circulation (2009) 2.30
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci U S A (2003) 2.28
Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ Res (2003) 2.26
Identification of a coronary vascular progenitor cell in the human heart. Proc Natl Acad Sci U S A (2009) 2.23
Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron (2009) 2.23
Notch1 regulates the fate of cardiac progenitor cells. Proc Natl Acad Sci U S A (2008) 2.22
The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility. J Biol Chem (2007) 2.20
Growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery. Circulation (2013) 2.19
How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes. Acta Biochim Biophys Sin (Shanghai) (2008) 2.19
Retracted Cardiomyogenesis in the aging and failing human heart. Circulation (2012) 2.16
A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome. Hum Mol Genet (2008) 2.13
Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice. Circ Res (2002) 2.11
Cardiac overexpression of alcohol dehydrogenase exacerbates chronic ethanol ingestion-induced myocardial dysfunction and hypertrophy: role of insulin signaling and ER stress. J Mol Cell Cardiol (2008) 2.11
Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia. Blood (2003) 2.06
Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci U S A (2008) 2.05
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias. Blood (2004) 2.03
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. Circulation (2009) 2.03
Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies. Circ Res (2011) 1.98
Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function. Circ Res (2006) 1.98
Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circ Res (2008) 1.97