Fully-automated white matter hyperintensity detection with anatomical prior knowledge and without FLAIR.

PubWeight™: 1.51‹?› | Rank: Top 4%

🔗 View Article (PMC 2864489)

Published in Inf Process Med Imaging on January 01, 2009

Authors

Christopher Schwarz1, Evan Fletcher, Charles DeCarli, Owen Carmichael

Author Affiliations

1: Computer Science Department, University of California, Davis, CA 95618, USA.

Articles citing this

Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative. Arch Neurol (2010) 1.94

A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment. Brain Imaging Behav (2012) 1.88

Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition. Brain (2011) 1.41

White matter lesions and brain gray matter volume in cognitively normal elders. Neurobiol Aging (2011) 1.26

Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism. JAMA Neurol (2013) 1.09

Subtypes based on cerebrospinal fluid and magnetic resonance imaging markers in normal elderly predict cognitive decline. Neurobiol Aging (2010) 1.09

Biological heterogeneity in ADNI amnestic mild cognitive impairment. Alzheimers Dement (2014) 1.01

Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls. Neurobiol Aging (2013) 0.95

Subgroup of ADNI normal controls characterized by atrophy and cognitive decline associated with vascular damage. Psychol Aging (2013) 0.94

Emerging β-amyloid pathology and accelerated cortical atrophy. JAMA Neurol (2014) 0.93

White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment. Alzheimers Dement (2013) 0.92

Automatic Detection of White Matter Hyperintensities in Healthy Aging and Pathology Using Magnetic Resonance Imaging: A Review. Neuroinformatics (2015) 0.88

Genetic architecture of resilience of executive functioning. Brain Imaging Behav (2012) 0.87

Predicting aggressive decline in mild cognitive impairment: the importance of white matter hyperintensities. JAMA Neurol (2014) 0.87

The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment. Alzheimers Dement (2015) 0.85

Mapping creatinine- and cystatin C-related white matter brain deficits in the elderly. Neurobiol Aging (2012) 0.85

White matter hyperintensities segmentation: a new semi-automated method. Front Aging Neurosci (2013) 0.84

An Automated Method for Segmenting White Matter Lesions through Multi-Level Morphometric Feature Classification with Application to Lupus. Front Hum Neurosci (2010) 0.83

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease. EMBO Mol Med (2016) 0.82

White matter signal abnormality quality differentiates mild cognitive impairment that converts to Alzheimer's disease from nonconverters. Neurobiol Aging (2015) 0.81

Suspected non-AD pathology in mild cognitive impairment. Neurobiol Aging (2015) 0.80

Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. PLoS One (2015) 0.79

Predicting Alzheimer's disease development: a comparison of cognitive criteria and associated neuroimaging biomarkers. Alzheimers Res Ther (2015) 0.79

Amyloid negativity in patients with clinically diagnosed Alzheimer disease and MCI. Neurology (2016) 0.79

Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement (2015) 0.79

Dysexecutive and amnesic AD subtypes defined by single indicator and modern psychometric approaches: relationships with SNPs in ADNI. Brain Imaging Behav (2012) 0.78

Application of variable threshold intensity to segmentation for white matter hyperintensities in fluid attenuated inversion recovery magnetic resonance images. Neuroradiology (2014) 0.78

Structural Neuroimaging Genetics Interactions in Alzheimer's Disease. J Alzheimers Dis (2015) 0.76

Automated Detection of Lupus White Matter Lesions in MRI. Front Neuroinform (2016) 0.75

White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy. Hippocampus (2016) 0.75

Memory is preserved in older adults taking AT1 receptor blockers. Alzheimers Res Ther (2017) 0.75

Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant. J Cereb Blood Flow Metab (2016) 0.75

Most edges in Markov random fields for white matter hyperintensity segmentation are worthless. Conf Proc IEEE Eng Med Biol Soc (2012) 0.75

Articles cited by this

Multimodality image registration by maximization of mutual information. IEEE Trans Med Imaging (1997) 16.80

Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI). Alzheimers Dement (2005) 7.90

Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. Stroke (1996) 7.81

Design of the Chicago Health and Aging Project (CHAP). J Alzheimers Dis (2003) 3.36

Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD. Neurology (2006) 3.22

Automated segmentation of multiple sclerosis lesions by model outlier detection. IEEE Trans Med Imaging (2001) 3.00

Regional spatial normalization: toward an optimal target. J Comput Assist Tomogr (2001) 2.74

Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study. Arch Neurol (2006) 2.46

Longitudinal study of blood pressure and white matter hyperintensities: the EVA MRI Cohort. Neurology (2001) 2.18

A fully automated method for quantifying and localizing white matter hyperintensities on MR images. Psychiatry Res (2006) 2.08

Fully automatic segmentation of white matter hyperintensities in MR images of the elderly. Neuroimage (2005) 1.91

Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study. Stroke (2006) 1.88

White matter hyperintensity progression and late-life depression outcomes. Arch Gen Psychiatry (2003) 1.46

An automated procedure for the assessment of white matter hyperintensities by multispectral (T1, T2, PD) MRI and an evaluation of its between-centre reproducibility based on two large community databases. Neuroradiology (2007) 1.20

Current concepts of analysis of cerebral white matter hyperintensities on magnetic resonance imaging. Top Magn Reson Imaging (2005) 1.05

Elastic registration of fMRI data using Bézier-spline transformations. IEEE Trans Med Imaging (2001) 1.01

Adaboost and Support Vector Machines for White Matter Lesion Segmentation in MR Images. Conf Proc IEEE Eng Med Biol Soc (2005) 0.99

Articles by these authors

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07

National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards. Stroke (2006) 6.94

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52

The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test battery. Alzheimer Dis Assoc Disord (2009) 5.50

Genomewide association studies of stroke. N Engl J Med (2009) 5.29

Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study. Stroke (2004) 4.56

Anatomical mapping of white matter hyperintensities (WMH): exploring the relationships between periventricular WMH, deep WMH, and total WMH burden. Stroke (2004) 3.80

Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol (2003) 3.75

Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study. Stroke (2010) 3.75

Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73

Vascular cognitive impairment. Lancet Neurol (2003) 3.73

Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA (2009) 3.62

Genetic variation in white matter hyperintensity volume in the Framingham Study. Stroke (2004) 3.13

Prevalence and correlates of silent cerebral infarcts in the Framingham offspring study. Stroke (2008) 2.84

Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition. Arch Neurol (2006) 2.79

Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol (2008) 2.71

Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol (2008) 2.69

Earlier onset of Alzheimer disease symptoms in latino individuals compared with anglo individuals. Arch Neurol (2005) 2.54

Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study. Arch Neurol (2006) 2.46

Framingham stroke risk profile and lowered cognitive performance. Stroke (2004) 2.46

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol (2011) 2.37

Progression of mild cognitive impairment to dementia in clinic- vs community-based cohorts. Arch Neurol (2009) 2.26

Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness. Proc Natl Acad Sci U S A (2002) 2.24

Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study. Lancet Neurol (2012) 2.17

Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08

White matter changes compromise prefrontal cortex function in healthy elderly individuals. J Cogn Neurosci (2006) 2.06

Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites. Arch Neurol (2009) 2.05

Chronic kidney disease is associated with white matter hyperintensity volume: the Northern Manhattan Study (NOMAS). Stroke (2007) 1.96

Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham Study. Stroke (2004) 1.96

Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative. Arch Neurol (2010) 1.94

Intensity non-uniformity correction using N3 on 3-T scanners with multichannel phased array coils. Neuroimage (2007) 1.93

The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life. Ann Neurol (2008) 1.92

Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke (2005) 1.91

Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Arch Neurol (2005) 1.91

White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibility. Stroke (2008) 1.84

Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol (2010) 1.80

Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet (2012) 1.79

White matter hyperintensity penumbra. Stroke (2011) 1.78

Brain MRI hippocampal volume and prediction of clinical status in a mild cognitive impairment trial. J Mol Neurosci (2002) 1.69

Radial width of the temporal horn: a sensitive measure in Alzheimer disease. AJNR Am J Neuroradiol (2002) 1.66

Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study. Stroke (2009) 1.66

Subclinical left ventricular dysfunction and silent cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Circulation (2013) 1.61

Cardiac index is associated with brain aging: the Framingham Heart Study. Circulation (2010) 1.57

Quantitative comparison of AIR, SPM, and the fully deformable model for atlas-based segmentation of functional and structural MR images. Hum Brain Mapp (2006) 1.57

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. J Neurosci (2004) 1.57

White matter hyperintensities and cognition: testing the reserve hypothesis. Neurobiol Aging (2009) 1.52

Patent foramen ovale, subclinical cerebrovascular disease, and ischemic stroke in a population-based cohort. J Am Coll Cardiol (2013) 1.52

Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet (2012) 1.51

Criterion-referenced validity of a neuropsychological test battery: equivalent performance in elderly Hispanics and non-Hispanic Whites. J Int Neuropsychol Soc (2005) 1.50

Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Arch Neurol (2008) 1.50

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke (2009) 1.47

Heterogeneity of cognitive trajectories in diverse older persons. Psychol Aging (2010) 1.44

Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition. Brain (2011) 1.41

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. J Alzheimers Dis (2008) 1.40

Computer-based cognitive training for mild cognitive impairment: results from a pilot randomized, controlled trial. Alzheimer Dis Assoc Disord (2009) 1.39

Different mechanisms of episodic memory failure in mild cognitive impairment. Neuropsychologia (2005) 1.37

Amylin deposition in the brain: A second amyloid in Alzheimer disease? Ann Neurol (2013) 1.35

Measuring cognitive reserve based on the decomposition of episodic memory variance. Brain (2010) 1.35

Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study. Stroke (2014) 1.32

Inflammatory biomarkers of vascular risk as correlates of leukoariosis. Stroke (2009) 1.32

Coevolution of white matter hyperintensities and cognition in the elderly. Neurology (2012) 1.28

Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimers Dement (2012) 1.27

Quantitative genetic modeling of regional brain volumes and cognitive performance in older male twins. Biol Psychol (2002) 1.27

Recruitment of a community-based cohort for research on diversity and risk of dementia. Alzheimer Dis Assoc Disord (2010) 1.25

The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction. JAMA Neurol (2013) 1.25

Hippocampal volume is associated with memory but not monmemory cognitive performance in patients with mild cognitive impairment. J Mol Neurosci (2003) 1.22

Periventricular white matter hyperintensities increase the likelihood of progression from amnestic mild cognitive impairment to dementia. J Neurol (2008) 1.18

Linking hippocampal structure and function to memory performance in an aging population. Arch Neurol (2009) 1.17

Association of serum soluble receptor for advanced glycation end-products with subclinical cerebrovascular disease: the Northern Manhattan Study (NOMAS). Atherosclerosis (2011) 1.17

Genome-wide scan for white matter hyperintensity: the Framingham Heart Study. Stroke (2005) 1.16

Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease. Arch Neurol (2008) 1.16

Vascular and degenerative processes differentially affect regional interhemispheric connections in normal aging, mild cognitive impairment, and Alzheimer disease. Stroke (2010) 1.15

A pilot study of vitamins to lower plasma homocysteine levels in Alzheimer disease. Am J Geriatr Psychiatry (2003) 1.14

Olfactory identification deficits and MCI in a multi-ethnic elderly community sample. Neurobiol Aging (2008) 1.10

Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism. JAMA Neurol (2013) 1.09

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol (2014) 1.08

Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study. Stroke (2013) 1.07

Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume. Neurobiol Aging (2011) 1.07

Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals. JAMA Neurol (2013) 1.06

Maximal brain size remains an important predictor of cognition in old age, independent of current brain pathology. Neurobiol Aging (2011) 1.06

Brain structure and cerebrovascular risk in cognitively impaired patients: Shanghai Community Brain Health Initiative-pilot phase. Arch Neurol (2010) 1.06

Current concepts of analysis of cerebral white matter hyperintensities on magnetic resonance imaging. Top Magn Reson Imaging (2005) 1.05

The association of magnetic resonance imaging measures with cognitive function in a biracial population sample. Arch Neurol (2010) 1.05

Managing and analysing data from a large-scale study on Framingham Offspring relating brain structure to cognitive function. Stat Med (2004) 1.04