Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

PubWeight™: 2.17‹?› | Rank: Top 2%

🔗 View Article (PMID 17099894)

Published in J Comp Neurol on January 01, 2007

Authors

Lee J Martin1, Zhiping Liu, Kevin Chen, Ann C Price, Yan Pan, Jason A Swaby, W Christopher Golden

Author Affiliations

1: Department of Pathology, Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, USA. martinl@jhmi.edu

Articles citing this

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci (2008) 5.89

Lithium delays progression of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2008) 5.37

Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1. Neuron (2009) 2.48

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain (2008) 1.92

Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice. Hum Mol Genet (2010) 1.70

Epigenetic regulation of motor neuron cell death through DNA methylation. J Neurosci (2011) 1.61

DNA repair deficiency in neurodegeneration. Prog Neurobiol (2011) 1.55

The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice. Exp Neurol (2009) 1.50

Neuronal cell death in neonatal hypoxia-ischemia. Ann Neurol (2011) 1.47

Mitochondrial DNA damage and repair in neurodegenerative disorders. DNA Repair (Amst) (2008) 1.31

Mitochondrial dysfunction and intracellular calcium dysregulation in ALS. Mech Ageing Dev (2010) 1.30

Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities. Hum Mol Genet (2009) 1.30

Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. PLoS One (2009) 1.29

DNA damage and repair: relevance to mechanisms of neurodegeneration. J Neuropathol Exp Neurol (2008) 1.25

SOD1 and mitochondria in ALS: a dangerous liaison. J Bioenerg Biomembr (2011) 1.24

Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain. Neuroscience (2007) 1.23

Biology of mitochondria in neurodegenerative diseases. Prog Mol Biol Transl Sci (2012) 1.22

Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease. PLoS One (2010) 1.18

The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis. Neurobiol Dis (2009) 1.15

Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases. Pharmaceuticals (Basel) (2010) 1.13

The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation. J Neurosci (2011) 1.13

Nitration of Hsp90 induces cell death. Proc Natl Acad Sci U S A (2013) 1.13

Glycinergic innervation of motoneurons is deficient in amyotrophic lateral sclerosis mice: a quantitative confocal analysis. Am J Pathol (2008) 1.11

Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis. PLoS One (2009) 1.10

The complex molecular biology of amyotrophic lateral sclerosis (ALS). Prog Mol Biol Transl Sci (2012) 1.05

Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice. Brain Struct Funct (2009) 1.03

Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci (2011) 1.02

The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis. Front Cell Neurosci (2014) 1.02

Motor neuron trophic factors: therapeutic use in ALS? Brain Res Rev (2010) 0.98

The mitochondrial permeability transition pore: a molecular target for amyotrophic lateral sclerosis therapy. Biochim Biophys Acta (2009) 0.98

α-synuclein assemblies sequester neuronal α3-Na+/K+-ATPase and impair Na+ gradient. EMBO J (2015) 0.98

Inhibitory synaptic regulation of motoneurons: a new target of disease mechanisms in amyotrophic lateral sclerosis. Mol Neurobiol (2011) 0.96

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model. J Biol Chem (2011) 0.96

The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS. Exp Neurol (2007) 0.96

The neuromediator glutamate, through specific substrate interactions, enhances mitochondrial ATP production and reactive oxygen species generation in nonsynaptic brain mitochondria. J Biol Chem (2009) 0.95

Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis. Curr Stem Cell Res Ther (2009) 0.95

Glial-derived prodegenerative signaling in the Drosophila neuromuscular system. Neuron (2011) 0.94

Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein. J Biol Chem (2008) 0.94

ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics. Amyotroph Lateral Scler Frontotemporal Degener (2014) 0.94

Nuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice. J Neuropathol Exp Neurol (2012) 0.94

Motor neuron-immune interactions: the vicious circle of ALS. J Neural Transm (Vienna) (2010) 0.93

Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis. IDrugs (2010) 0.93

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis. J Cell Biochem (2012) 0.92

Mitochondrial DNMT3A and DNA methylation in skeletal muscle and CNS of transgenic mouse models of ALS. Front Cell Neurosci (2013) 0.92

A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neurons. Exp Neurol (2011) 0.91

Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo. Neurobiol Dis (2009) 0.91

Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics. Proc Natl Acad Sci U S A (2012) 0.88

Seeking homeostasis: temporal trends in respiration, oxidation, and calcium in SOD1 G93A Amyotrophic Lateral Sclerosis mice. Front Cell Neurosci (2015) 0.87

Adherent monomer-misfolded SOD1. PLoS One (2008) 0.87

Redox regulation in amyotrophic lateral sclerosis. Oxid Med Cell Longev (2013) 0.86

Aberrant regulation of DNA methylation in amyotrophic lateral sclerosis: a new target of disease mechanisms. Neurotherapeutics (2013) 0.86

The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease. J Biol Chem (2010) 0.86

Mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice. Neurobiol Aging (2013) 0.86

Mitochondrial pathobiology in ALS. J Bioenerg Biomembr (2011) 0.86

GNX-4728, a novel small molecule drug inhibitor of mitochondrial permeability transition, is therapeutic in a mouse model of amyotrophic lateral sclerosis. Front Cell Neurosci (2014) 0.84

An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons. Toxicol Pathol (2010) 0.83

Clathrin assembly proteins AP180 and CALM in the embryonic rat brain. J Comp Neurol (2010) 0.83

Motor neuron death in ALS: programmed by astrocytes? Neuron (2014) 0.83

Neuroprotective Effect of Bexarotene in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis. Front Cell Neurosci (2015) 0.82

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration. Nat Neurosci (2014) 0.82

Specific electron transport chain abnormalities in amyotrophic lateral sclerosis. J Neurol (2009) 0.82

Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases. Neurotherapeutics (2013) 0.81

Species-dependent neuropathology in transgenic SOD1 pigs. Cell Res (2014) 0.80

An overview of DNA repair in amyotrophic lateral sclerosis. ScientificWorldJournal (2011) 0.80

Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Front Cell Neurosci (2015) 0.79

TDP-43/FUS in motor neuron disease: Complexity and challenges. Prog Neurobiol (2016) 0.79

Oscillating gradient diffusion MRI reveals unique microstructural information in normal and hypoxia-ischemia injured mouse brains. Magn Reson Med (2014) 0.79

c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis. PLoS One (2012) 0.79

Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology. Am J Physiol Regul Integr Comp Physiol (2011) 0.79

Intraspinal stem cell transplantation for amyotrophic lateral sclerosis. Ann Neurol (2016) 0.79

Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis. Front Cell Neurosci (2015) 0.77

Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis. Mol Neurodegener (2011) 0.77

Motoneuron subtypes show specificity in glycine receptor channel abnormalities in a transgenic mouse model of amyotrophic lateral sclerosis. Channels (Austin) (2011) 0.77

Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration. Mech Ageing Dev (2016) 0.76

Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis. Front Cell Neurosci (2015) 0.76

Motor neuron degeneration in a mouse model of seipinopathy. Cell Death Dis (2013) 0.76

Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging. Nat Commun (2016) 0.76

Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS. Neurobiol Dis (2016) 0.76

A method to immunolabel rodent spinal cord neurons and glia for molecular study in specific laser microdissected cells involved in neurodegenerative disorders. J Mol Histol (2009) 0.76

Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration. Cell Mol Neurobiol (2009) 0.76

αCAR IGF-1 vector targeting of motor neurons ameliorates disease progression in ALS mice. Ann Clin Transl Neurol (2016) 0.75

Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo. Stem Cell Reports (2017) 0.75

Cortical hierarchy governs rat claustrocortical circuit organization. J Comp Neurol (2016) 0.75

Prion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage response. World J Virol (2015) 0.75

Chronic EMGs in treadmill running SOD1 mice reveal early changes in muscle activation. J Physiol (2017) 0.75

DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro. PLoS One (2017) 0.75

Sodium pump regulation of locomotor control circuits. J Neurophysiol (2017) 0.75

The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches. Front Aging Neurosci (2017) 0.75

Articles by these authors

Comparative metagenomics of microbial communities. Science (2005) 25.88

A genome-wide map of conserved microRNA targets in C. elegans. Curr Biol (2006) 10.14

The landscape of C. elegans 3'UTRs. Science (2010) 3.32

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci (2006) 2.85

Early pottery at 20,000 years ago in Xianrendong Cave, China. Science (2012) 2.73

A transient placental source of serotonin for the fetal forebrain. Nature (2011) 2.71

Use of qigong therapy in the detoxification of heroin addicts. Altern Ther Health Med (2002) 2.28

Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection. J Med Chem (2006) 2.09

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem (2012) 2.04

Systemic dissemination of Clostridium difficile toxins A and B is associated with severe, fatal disease in animal models. J Infect Dis (2011) 1.98

Hyperoxic resuscitation improves survival but worsens neurologic outcome in a rat polytrauma model of traumatic brain injury plus hemorrhagic shock. J Trauma Acute Care Surg (2015) 1.97

Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma. Clin Cancer Res (2008) 1.94

Human neural stem cells induce functional myelination in mice with severe dysmyelination. Sci Transl Med (2012) 1.82

MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2. Biochem Biophys Res Commun (2010) 1.80

Herpes simplex virus infections in preterm infants. Pediatrics (2006) 1.69

Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease. Exp Neurol (2006) 1.64

GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein. J Biol Chem (2009) 1.56

Monoamine oxidase inactivation: from pathophysiology to therapeutics. Adv Drug Deliv Rev (2008) 1.56

The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice. Exp Neurol (2009) 1.50

Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches. J Mass Spectrom (2008) 1.49

Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway. Proc Natl Acad Sci U S A (2006) 1.46

Cardiovascular actions and therapeutic potential of tanshinone IIA. Atherosclerosis (2011) 1.45

Proteome dynamics during C2C12 myoblast differentiation. Mol Cell Proteomics (2005) 1.36

Mouse relapse model of Clostridium difficile infection. Infect Immun (2011) 1.36

Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload. Circ Res (2009) 1.32

TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells. Am J Physiol Gastrointest Liver Physiol (2008) 1.31

Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation. J Neurosci (2005) 1.26

Non-equilibrium allele frequency spectra via spectral methods. Theor Popul Biol (2011) 1.26

Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function. Toxicol Sci (2005) 1.25

Rapid CT diagnosis of acute appendicitis with IV contrast material. Emerg Radiol (2005) 1.22

A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection. Infect Immun (2012) 1.22

Novel monoamine oxidase A knock out mice with human-like spontaneous mutation. Neuroreport (2008) 1.21

Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization. J Med Chem (2007) 1.21

Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1. J Biol Chem (2006) 1.20

Helicobacter bilis triggers persistent immune reactivity to antigens derived from the commensal bacteria in gnotobiotic C3H/HeN mice. Gut (2006) 1.20

De novo transcriptome sequencing of radish (Raphanus sativus L.) and analysis of major genes involved in glucosinolate metabolism. BMC Genomics (2013) 1.19

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage. Autophagy (2012) 1.18

Mass spectrometry combined with oxidative labeling for exploring protein structure and folding. Mass Spectrom Rev (2010) 1.17

Histopathological correlates of magnetic resonance imaging-defined chronic perinatal white matter injury. Ann Neurol (2011) 1.15

Monoamine oxidase A knockout mice exhibit impaired nicotine preference but normal responses to novel stimuli. Hum Mol Genet (2006) 1.15

International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers. J Magn Reson Imaging (2010) 1.14

The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation. J Neurosci (2011) 1.13

Dual functions of transcription factors, transforming growth factor-beta-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B gene. J Biol Chem (2004) 1.13

Mutations in TRIOBP, which encodes a putative cytoskeletal-organizing protein, are associated with nonsyndromic recessive deafness. Am J Hum Genet (2005) 1.10

Radiocarbon dating of charcoal and bone collagen associated with early pottery at Yuchanyan Cave, Hunan Province, China. Proc Natl Acad Sci U S A (2009) 1.10

Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction. Proc Natl Acad Sci U S A (2006) 1.08

Molecular regulation of DNA damage-induced apoptosis in neurons of cerebral cortex. Cereb Cortex (2008) 1.08

Large-area compliant tactile sensors using printed carbon nanotube active-matrix backplanes. Adv Mater (2015) 1.07

Correlating gene expression variation with cis-regulatory polymorphism in Saccharomyces cerevisiae. Genome Biol Evol (2010) 1.06

Molecular epidemiology of rabies in Guangxi Province, south of China. J Clin Virol (2007) 1.05

Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins. J Neurochem (2003) 1.05

Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts. Antioxid Redox Signal (2013) 1.04

Glyceraldehyde-3-phosphate dehydrogenase-monoamine oxidase B-mediated cell death-induced by ethanol is prevented by rasagiline and 1-R-aminoindan. Neurotox Res (2009) 1.04

Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation. Transl Res (2012) 1.02

Regulation of monoamine oxidase A by the SRY gene on the Y chromosome. FASEB J (2009) 1.00

Tobacco use and dependence in Asian American and Pacific Islander adolescents: a review of the literature. J Ethn Subst Abuse (2007) 1.00

Behavioral disinhibition and reduced anxiety-like behaviors in monoamine oxidase B-deficient mice. Neuropsychopharmacology (2009) 0.99

Development of viral nanoparticles for efficient intracellular delivery. Nanoscale (2012) 0.99

Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent. J Neurobiol (2002) 0.99

Activation of human monoamine oxidase B gene expression by a protein kinase C MAPK signal transduction pathway involves c-Jun and Egr-1. J Biol Chem (2002) 0.98

The mitochondrial permeability transition pore: a molecular target for amyotrophic lateral sclerosis therapy. Biochim Biophys Acta (2009) 0.98

Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation. J Biol Chem (2003) 0.97

Integrating graph partitioning and matching for trajectory analysis in video surveillance. IEEE Trans Image Process (2012) 0.97

High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature. Sci Rep (2013) 0.97

A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. Biol Psychiatry (2009) 0.97

Monoamine oxidase A and A/B knockout mice display autistic-like features. Int J Neuropsychopharmacol (2012) 0.97

Atorvastatin reduces vascular endothelial growth factor (VEGF) expression in human non-small cell lung carcinomas (NSCLCs) via inhibition of reactive oxygen species (ROS) production. Mol Oncol (2011) 0.96

Relationship between self-reported task persistence and history of quitting smoking, plans for quitting smoking, and current smoking status in adolescents. Addict Behav (2006) 0.96

Functional role of Ile264 in CYP2C8: mutations affect haem incorporation and catalytic activity. Drug Metab Pharmacokinet (2008) 0.95

Trying to understand why horrible things happen: attribution, shame, and symptom development following sexual abuse. Child Maltreat (2002) 0.95

Adult olfactory bulb neural precursor cell grafts provide temporary protection from motor neuron degeneration, improve motor function, and extend survival in amyotrophic lateral sclerosis mice. J Neuropathol Exp Neurol (2007) 0.94

Direct, complex effects of estrogens on basal forebrain cholinergic neurons. Exp Neurol (2005) 0.94

Biomimetic entry to the sarpagan family of indole alkaloids: total synthesis of +-geissoschizine and +-N-methylvellosimine. J Am Chem Soc (2003) 0.94

Social deficits and perseverative behaviors, but not overt aggression, in MAO-A hypomorphic mice. Neuropsychopharmacology (2011) 0.94

Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors. Mol Endocrinol (2006) 0.94

Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells. Eur J Pharmacol (2012) 0.94

Retinoic acid activates monoamine oxidase B promoter in human neuronal cells. J Biol Chem (2009) 0.94

Analysis of conserved active site residues in monoamine oxidase A and B and their three-dimensional molecular modeling. J Biol Chem (2002) 0.93

A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene. Drug Metab Dispos (2003) 0.93

Fenofibrate ameliorates cardiac hypertrophy by activation of peroxisome proliferator-activated receptor-α partly via preventing p65-NFκB binding to NFATc4. Mol Cell Endocrinol (2013) 0.93

Monoamine oxidases regulate telencephalic neural progenitors in late embryonic and early postnatal development. J Neurosci (2010) 0.92

Increased CYP4B1 mRNA is associated with the inhibition of dextran sulfate sodium-induced colitis by caffeic acid in mice. Exp Biol Med (Maywood) (2009) 0.92

Water channels and zymogen granules in salivary glands. J Pharmacol Sci (2006) 0.92

Human piRNAs are under selection in Africans and repress transposable elements. Mol Biol Evol (2011) 0.92

Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol (2012) 0.90

Simple conversion of enamines to 2H-azirines and their rearrangements under thermal conditions. Org Lett (2009) 0.90

Maladaptive defensive behaviours in monoamine oxidase A-deficient mice. Int J Neuropsychopharmacol (2010) 0.89

Infusion of imaging and therapeutic molecules into the plant virus-based carrier cowpea mosaic virus: cargo-loading and delivery. J Control Release (2013) 0.89

Dopamine receptor modulation of hypoxic-ischemic neuronal injury in striatum of newborn piglets. J Cereb Blood Flow Metab (2007) 0.89

Developmental expression pattern of monoamine oxidases in sensory organs and neural crest derivatives. J Comp Neurol (2003) 0.88

Striatal damage and oxidative stress induced by the mitochondrial toxin malonate are reduced in clorgyline-treated rats and MAO-A deficient mice. Neurochem Res (2004) 0.88

A novel modified soft probe for identifying the distal cut end in single canalicular laceration. Br J Ophthalmol (2013) 0.88

Induction of differential immune reactivity to members of the flora of gnotobiotic mice following colonization with Helicobacter bilis or Brachyspira hyodysenteriae. Microbes Infect (2006) 0.88

Kinetics of activity-evoked pH transients and extracellular pH buffering in rat hippocampal slices. J Neurophysiol (2006) 0.87

Pulsed hydrogen/deuterium exchange mass spectrometry for time-resolved membrane protein folding studies. J Mass Spectrom (2012) 0.87

Curcumin inhibits tumor proliferation induced by neutrophil elastase through the upregulation of α1-antitrypsin in lung cancer. Mol Oncol (2012) 0.87

Effects of Baicalin and Octreotide on the serum TNF-alpha level and apoptosis in multiple organs of rats with severe acute pancreatitis. Inflammation (2009) 0.87