Published in Ann N Y Acad Sci on August 01, 2006
Endogenous opiates and behavior: 2006. Peptides (2007) 0.92
Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci (2013) 0.83
Identification and Characterization of RNA Aptamers: A Long Aptamer Blocks the AMPA Receptor and a Short Aptamer Blocks Both AMPA and Kainate Receptors. J Biol Chem (2017) 0.75
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity. J Neurochem (2004) 1.58
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness? Exp Neurol (2012) 1.50
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochem Res (2003) 1.34
Insulin in central nervous system: more than just a peripheral hormone. J Aging Res (2012) 1.33
Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice. J Neurochem (2007) 1.32
Cytochrome c oxidase is decreased in Alzheimer's disease platelets. Neurobiol Aging (2004) 1.30
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J Neurosci (2005) 1.29
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway. J Neurosci (2009) 1.23
Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures. J Neurosci (2005) 1.19
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors. J Neurosci (2006) 1.19
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis (2007) 1.19
Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol (2007) 1.18
An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity. Neurobiol Dis (2006) 1.17
CXCL12/CXCR4 promotes motility and proliferation of glioma cells. Cancer Biol Ther (2010) 1.17
Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets (2008) 1.15
Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy (2007) 1.14
Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship. Chem Res Toxicol (2006) 1.13
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. J Neurochem (2005) 1.11
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs. Brain Res Rev (2008) 1.11
Metformin promotes isolated rat liver mitochondria impairment. Mol Cell Biochem (2007) 1.10
The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway. Neurobiol Dis (2008) 1.09
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. J Alzheimers Dis (2009) 1.08
Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids. Antioxid Redox Signal (2009) 1.08
Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biol Toxicol (2008) 1.08
Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background. Mitochondrion (2008) 1.07
Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. J Neurol Sci (2007) 1.07
Effect of amyloid beta-peptide on permeability transition pore: a comparative study. J Neurosci Res (2002) 1.07
Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview. Mini Rev Med Chem (2008) 1.07
Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats. Eur J Neurosci (2003) 1.06
Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine. Brain Res (2006) 1.05
Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure. J Biol Chem (2006) 1.05
Overactivation of calcineurin induced by amyloid-beta and prion proteins. Neurochem Int (2008) 1.04
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress. Diabetes (2006) 1.04
Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation. Brain Res (2012) 1.04
Cholesterol and statins in Alzheimer's disease: current controversies. Exp Neurol (2009) 1.03
Alzheimer's disease: a lesson from mitochondrial dysfunction. Antioxid Redox Signal (2007) 1.02
Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes. Med Chem (2008) 1.01
Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet. Scand J Gastroenterol (2008) 0.99
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. Free Radic Biol Med (2003) 0.99
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med (2005) 0.98
Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure. Diabetes (2003) 0.98
Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria. Brain Res (2002) 0.98
Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide. J Neurosci Res (2004) 0.98
Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons. Neurobiol Dis (2007) 0.97
Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology. Neurobiol Dis (2009) 0.97
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease. Neurochem Int (2009) 0.96
Epigenetics in neurodegeneration: a new layer of complexity. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.96
Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus. Brain Res (2003) 0.96
The R6 lines of transgenic mice: a model for screening new therapies for Huntington's disease. Brain Res Rev (2008) 0.96
Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors. Neuropharmacology (2013) 0.95
Adenosine A3 receptors are located in neurons of the rat hippocampus. Neuroreport (2003) 0.95
FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures. Neurobiol Dis (2004) 0.94
Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides. Cell Cycle (2009) 0.94
Neurodegeneration in an Abeta-induced model of Alzheimer's disease: the role of Cdk5. Aging Cell (2009) 0.94
Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease? Curr Aging Sci (2010) 0.93
Lack of evidence for functional TRPV1 vanilloid receptors in rat hippocampal nerve terminals. Neurosci Lett (2006) 0.93
Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res (2005) 0.93
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers. Aging Cell (2012) 0.93
Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies. Cell Mol Neurobiol (2007) 0.92
Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - from clinical features to the bench. Curr Drug Targets (2010) 0.92
Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex. Epilepsia (2005) 0.92
Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons. J Neurochem (2007) 0.92
Microtubule depolymerization potentiates alpha-synuclein oligomerization. Front Aging Neurosci (2010) 0.92
Insulin is a two-edged knife on the brain. J Alzheimers Dis (2009) 0.92
Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression. Biochim Biophys Acta (2008) 0.91
ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells. BMB Rep (2009) 0.91
Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic. Hum Mol Genet (2012) 0.91
Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway. J Alzheimers Dis (2011) 0.90
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes (2012) 0.89
Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death. BMC Cell Biol (2007) 0.89
Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts. Cancer Chemother Pharmacol (2009) 0.89
Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126). J Neurochem (2007) 0.89
Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease. Free Radic Biol Med (2008) 0.88
Expression and subcellular localization of a novel nuclear acetylcholinesterase protein. J Biol Chem (2007) 0.88
Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801. Exp Neurol (2007) 0.88
Modification of adenosine A1 and A2A receptor density in the hippocampus of streptozotocin-induced diabetic rats. Neurochem Int (2005) 0.88
Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients. Biochem Biophys Res Commun (2008) 0.88
Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells. Biochim Biophys Acta (2013) 0.88
Mitochondria as a therapeutic target in Alzheimer's disease and diabetes. CNS Neurol Disord Drug Targets (2009) 0.87
Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons. J Cell Biochem (2006) 0.87
Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α. Neurobiol Dis (2011) 0.87
Comparative study of microglia activation induced by amyloid-beta and prion peptides: role in neurodegeneration. J Neurosci Res (2006) 0.87
Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen. J Steroid Biochem Mol Biol (2010) 0.86
IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice. Mol Neurobiol (2013) 0.86
Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats. Toxicol Appl Pharmacol (2007) 0.86
Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress. J Alzheimers Dis (2013) 0.86
Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats. J Neurochem (2005) 0.85
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions. Neurobiol Aging (2011) 0.85
Neurotoxicity of heroin-cocaine combinations in rat cortical neurons. Toxicology (2010) 0.85
Bioenergetic dysfunction in Huntington's disease human cybrids. Exp Neurol (2011) 0.84