Published in Cancer Res on November 15, 2006
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The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas. Br J Cancer (2009) 1.70
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A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature (2005) 14.65
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Noise in eukaryotic gene expression. Nature (2003) 13.01
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Oct4-induced pluripotency in adult neural stem cells. Cell (2009) 6.50
Lung cancer susceptibility locus at 5p15.33. Nat Genet (2008) 5.99
Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci U S A (2008) 5.94
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus. Sci Transl Med (2010) 5.54
Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39
Prediction and measurement of an autoregulatory genetic module. Proc Natl Acad Sci U S A (2003) 5.07
Engineered riboregulators enable post-transcriptional control of gene expression. Nat Biotechnol (2004) 5.07
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
DNA sequencing of maternal plasma to detect Down syndrome: an international clinical validation study. Genet Med (2011) 4.98
Phenotypic consequences of promoter-mediated transcriptional noise. Mol Cell (2006) 4.93
Programmable cells: interfacing natural and engineered gene networks. Proc Natl Acad Sci U S A (2004) 4.72
The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups. J Thorac Cardiovasc Surg (2012) 4.68
Comparative genome sequencing of Escherichia coli allows observation of bacterial evolution on a laboratory timescale. Nat Genet (2006) 4.44
Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting. Am J Obstet Gynecol (2011) 4.18
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet (2009) 4.11
A bottom-up approach to gene regulation. Nature (2006) 4.03
Bacterial charity work leads to population-wide resistance. Nature (2010) 3.50
Predictive accuracy of the Liverpool Lung Project risk model for stratifying patients for computed tomography screening for lung cancer: a case-control and cohort validation study. Ann Intern Med (2012) 3.45
Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection. Nat Med (2007) 3.34
DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study. Genet Med (2012) 3.18
Digital PCR for the molecular detection of fetal chromosomal aneuploidy. Proc Natl Acad Sci U S A (2007) 3.13
The use of MassARRAY technology for high throughput genotyping. Adv Biochem Eng Biotechnol (2002) 3.08
Whole-genome annotation by using evidence integration in functional-linkage networks. Proc Natl Acad Sci U S A (2004) 2.93
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell (2007) 2.83
Association testing by DNA pooling: an effective initial screen. Proc Natl Acad Sci U S A (2002) 2.79
Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Res (2009) 2.76
Occupational exposure to crystalline silica and risk of lung cancer: a multicenter case-control study in Europe. Epidemiology (2007) 2.60
A high-throughput gene expression analysis technique using competitive PCR and matrix-assisted laser desorption ionization time-of-flight MS. Proc Natl Acad Sci U S A (2003) 2.19
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology (2011) 2.01
MALDI-TOF mass spectrometry-based SNP genotyping. Methods Mol Biol (2003) 1.99
RNase T1 mediated base-specific cleavage and MALDI-TOF MS for high-throughput comparative sequence analysis. Nucleic Acids Res (2003) 1.99
Lung cancer risk prediction to select smokers for screening CT--a model based on the Italian COSMOS trial. Cancer Prev Res (Phila) (2011) 1.98
Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. Int J Epidemiol (2009) 1.97
MALDI-TOF mass spectrometry: a versatile tool for high-performance DNA analysis. Mol Biotechnol (2004) 1.95
Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer (2009) 1.94
RNA visualization in live bacterial cells using fluorescent protein complementation. Nat Methods (2007) 1.92
High-throughput MALDI-TOF discovery of genomic sequence polymorphisms. Genome Res (2004) 1.92
Cytosine methylation profiling of cancer cell lines. Proc Natl Acad Sci U S A (2008) 1.91
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. Blood (2007) 1.84
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Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet (2012) 1.77
Direct molecular haplotyping of long-range genomic DNA with M1-PCR. Proc Natl Acad Sci U S A (2003) 1.74
Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. PLoS One (2011) 1.72
Association of the PDCD5 locus with lung cancer risk and prognosis in smokers. J Clin Oncol (2006) 1.71
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc Natl Acad Sci U S A (2010) 1.66
Hypermethylation of genes for diagnosis and risk stratification of prostate cancer. Cancer Invest (2009) 1.64
Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma. Proc Natl Acad Sci U S A (2008) 1.64
Designing isoform-specific peptide disruptors of protein kinase A localization. Proc Natl Acad Sci U S A (2003) 1.61
Genetic switchboard for synthetic biology applications. Proc Natl Acad Sci U S A (2012) 1.60
Role of ICAM1 in invasion of human breast cancer cells. Carcinogenesis (2005) 1.59
Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet (2012) 1.57
Lung cancer risk prediction: a tool for early detection. Int J Cancer (2007) 1.51
Expression profiling of primary non-small cell lung cancer for target identification. Oncogene (2002) 1.51
International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiol Biomarkers Prev (2008) 1.51
Quantitative DNA methylation predicts survival in adult acute myeloid leukemia. Blood (2009) 1.50
Multiplexed discovery of sequence polymorphisms using base-specific cleavage and MALDI-TOF MS. Nucleic Acids Res (2005) 1.49
A prognostic DNA methylation signature for stage I non-small-cell lung cancer. J Clin Oncol (2013) 1.47
A new method for accurate assessment of DNA quality after bisulfite treatment. Nucleic Acids Res (2007) 1.46
Quantification of fetal DNA by use of methylation-based DNA discrimination. Clin Chem (2010) 1.45
DNA methylation epigenotypes in breast cancer molecular subtypes. Breast Cancer Res (2010) 1.44
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Multi-population classical HLA type imputation. PLoS Comput Biol (2013) 1.43
Detection of microdeletion 22q11.2 in a fetus by next-generation sequencing of maternal plasma. Clin Chem (2012) 1.41
A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer. Hum Mol Genet (2002) 1.40
Haplotyping in biomedicine-practical challenges. Nat Biotechnol (2005) 1.38
Novel mass spectrometry-based tool for genotypic identification of mycobacteria. J Clin Microbiol (2004) 1.37
Monosomy 3 in uveal melanoma: correlation with clinical and histologic predictors of survival. Invest Ophthalmol Vis Sci (2003) 1.34
Amino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphism. Proc Natl Acad Sci U S A (2003) 1.33