Published in Proc Natl Acad Sci U S A on December 22, 2009
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
Genotype imputation with thousands of genomes. G3 (Bethesda) (2011) 8.77
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
Genomic ancestry of North Africans supports back-to-Africa migrations. PLoS Genet (2012) 2.51
Blindness and visual impairment in an urban West African population: the Tema Eye Survey. Ophthalmology (2012) 2.24
Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Genet Med (2010) 2.09
Polar and brown bear genomes reveal ancient admixture and demographic footprints of past climate change. Proc Natl Acad Sci U S A (2012) 1.98
Genome-wide data substantiate Holocene gene flow from India to Australia. Proc Natl Acad Sci U S A (2013) 1.78
Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet (2012) 1.75
Learning about human population history from ancient and modern genomes. Nat Rev Genet (2011) 1.74
Reconstructing the population genetic history of the Caribbean. PLoS Genet (2013) 1.68
Ancestral components of admixed genomes in a Mexican cohort. PLoS Genet (2011) 1.67
Dating the age of admixture via wavelet transform analysis of genome-wide data. Genome Biol (2011) 1.65
The genetic ancestry of African Americans, Latinos, and European Americans across the United States. Am J Hum Genet (2014) 1.61
Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma. J Allergy Clin Immunol (2010) 1.57
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50
Inference of relationships in population data using identity-by-descent and identity-by-state. PLoS Genet (2011) 1.43
A genomic portrait of haplotype diversity and signatures of selection in indigenous southern African populations. PLoS Genet (2015) 1.43
Quantifying effects of environmental and geographical factors on patterns of genetic differentiation. Mol Ecol (2011) 1.42
Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe Study. Cancer Epidemiol Biomarkers Prev (2011) 1.41
PCAdmix: principal components-based assignment of ancestry along each chromosome in individuals with admixed ancestry from two or more populations. Hum Biol (2012) 1.37
Validation of a small set of ancestral informative markers for control of population admixture in African Americans. Am J Epidemiol (2011) 1.36
Consistency of genome-wide associations across major ancestral groups. Hum Genet (2011) 1.35
Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies. PLoS Genet (2012) 1.33
An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal resequencing data. Mol Biol Evol (2011) 1.33
Y-chromosomal variation in sub-Saharan Africa: insights into the history of Niger-Congo groups. Mol Biol Evol (2010) 1.32
Colloquium paper: working toward a synthesis of archaeological, linguistic, and genetic data for inferring African population history. Proc Natl Acad Sci U S A (2010) 1.27
Analyses of a set of 128 ancestry informative single-nucleotide polymorphisms in a global set of 119 population samples. Investig Genet (2011) 1.22
Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine. PLoS One (2011) 1.21
Genetic structure in village dogs reveals a Central Asian domestication origin. Proc Natl Acad Sci U S A (2015) 1.21
A quantitative comparison of the similarity between genes and geography in worldwide human populations. PLoS Genet (2012) 1.17
A general mechanistic model for admixture histories of hybrid populations. Genetics (2011) 1.17
A genomic analysis identifies a novel component in the genetic structure of sub-Saharan African populations. Eur J Hum Genet (2010) 1.15
Genetic diversity in India and the inference of Eurasian population expansion. Genome Biol (2010) 1.13
The promise and limitations of population exomics for human evolution studies. Genome Biol (2011) 1.13
Fine-scale population structure and the era of next-generation sequencing. Hum Mol Genet (2010) 1.12
Evolutionary genomics of dog domestication. Mamm Genome (2012) 1.11
Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry. Sci Rep (2014) 1.11
Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture. Am J Hum Genet (2014) 1.10
Haplotype variation and genotype imputation in African populations. Genet Epidemiol (2011) 1.10
Genome-wide detection of natural selection in African Americans pre- and post-admixture. Genome Res (2011) 1.09
Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans. PLoS Genet (2013) 1.08
Demonstration of Protein-Based Human Identification Using the Hair Shaft Proteome. PLoS One (2016) 1.08
Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. Hum Mol Genet (2011) 1.08
Principal components analysis of population admixture. PLoS One (2012) 1.07
Exploring population admixture dynamics via empirical and simulated genome-wide distribution of ancestral chromosomal segments. Am J Hum Genet (2012) 1.07
Early back-to-Africa migration into the Horn of Africa. PLoS Genet (2014) 1.06
Dissecting the within-Africa ancestry of populations of African descent in the Americas. PLoS One (2011) 1.06
The lengths of admixture tracts. Genetics (2014) 1.06
Patterns of admixture and population structure in native populations of Northwest North America. PLoS Genet (2014) 1.05
Mapping genes that predict treatment outcome in admixed populations. Pharmacogenomics J (2010) 1.05
Prevalence of glaucoma in an urban West African population: the Tema Eye Survey. JAMA Ophthalmol (2013) 1.05
Inference of human continental origin and admixture proportions using a highly discriminative ancestry informative 41-SNP panel. Investig Genet (2013) 1.04
Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases. PLoS One (2014) 1.04
A genome-wide association study of prostate cancer in West African men. Hum Genet (2013) 1.02
Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations. BMC Genet (2012) 1.01
Softwares and methods for estimating genetic ancestry in human populations. Hum Genomics (2013) 1.00
Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans. PLoS One (2011) 0.99
Personal genomes, quantitative dynamic omics and personalized medicine. Quant Biol (2013) 0.98
The Great Migration and African-American Genomic Diversity. PLoS Genet (2016) 0.97
Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma. J Allergy Clin Immunol (2012) 0.97
Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from Non-African populations. Genome Biol Evol (2013) 0.96
Combining markers into haplotypes can improve population structure inference. Genetics (2011) 0.96
Leukocyte Cell-Derived Chemotaxin 2-Associated Amyloidosis: A Recently Recognized Disease with Distinct Clinicopathologic Characteristics. Clin J Am Soc Nephrol (2015) 0.95
Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations. Proc Natl Acad Sci U S A (2015) 0.95
Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study. PLoS One (2012) 0.94
Genetic variation and adaptation in Africa: implications for human evolution and disease. Cold Spring Harb Perspect Biol (2014) 0.94
Coalescence-time distributions in a serial founder model of human evolutionary history. Genetics (2011) 0.94
The effect of recent admixture on inference of ancient human population history. Genetics (2010) 0.93
Looking to the future: incorporating genomic information into disparities research to reduce measurement error and selection bias. Health Serv Res (2012) 0.93
Appetite regulation genes are associated with body mass index in black South African adolescents: a genetic association study. BMJ Open (2012) 0.93
Pharmacogenomics of warfarin in populations of African descent. Br J Clin Pharmacol (2013) 0.93
A test of the influence of continental axes of orientation on patterns of human gene flow. Am J Phys Anthropol (2011) 0.92
Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics. J Hypertens (2013) 0.91
Enhanced methods for local ancestry assignment in sequenced admixed individuals. PLoS Comput Biol (2014) 0.91
Genome-wide ancestry of 17th-century enslaved Africans from the Caribbean. Proc Natl Acad Sci U S A (2015) 0.91
Turkish population structure and genetic ancestry reveal relatedness among Eurasian populations. Ann Hum Genet (2012) 0.91
Unravelling the hidden ancestry of American admixed populations. Nat Commun (2015) 0.90
Genetic structure in African populations: implications for human demographic history. Cold Spring Harb Symp Quant Biol (2010) 0.90
Genomics assisted ancestry deconvolution in grape. PLoS One (2013) 0.89
Estrogen-related genes and their contribution to racial differences in breast cancer risk. Cancer Causes Control (2012) 0.89
Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium. Hum Reprod Update (2013) 0.89
Beyond 2/3 and 1/3: The Complex Signatures of Sex-Biased Admixture on the X Chromosome. Genetics (2015) 0.88
Anisotropic isolation by distance: the main orientations of human genetic differentiation. Mol Biol Evol (2012) 0.88
Detecting directional selection in the presence of recent admixture in African-Americans. Genetics (2010) 0.88
Comprehensive evaluation of imputation performance in African Americans. J Hum Genet (2012) 0.87
Effect of Genetic African Ancestry on eGFR and Kidney Disease. J Am Soc Nephrol (2014) 0.87
A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nat Commun (2016) 0.87
NetView: a high-definition network-visualization approach to detect fine-scale population structures from genome-wide patterns of variation. PLoS One (2012) 0.87
Distribution of parental genome blocks in recombinant inbred lines. Genetics (2011) 0.86
Assessment of genetic ancestry and population substructure in Costa Rica by analysis of individuals with a familial history of mental disorder. Ann Hum Genet (2010) 0.86
Geographic sampling scheme as a determinant of the major axis of genetic variation in principal components analysis. Mol Biol Evol (2012) 0.86
Accurate local-ancestry inference in exome-sequenced admixed individuals via off-target sequence reads. Am J Hum Genet (2013) 0.86
HapFABIA: identification of very short segments of identity by descent characterized by rare variants in large sequencing data. Nucleic Acids Res (2013) 0.86
A panel of ancestry informative markers for the complex five-way admixed South African coloured population. PLoS One (2013) 0.85
Phenotyping clinical disorders: lessons learned from pelvic organ prolapse. Am J Obstet Gynecol (2012) 0.85
Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and structure. BMC Bioinformatics (2011) 0.85
Genome-wide association study of age at menarche in African-American women. Hum Mol Genet (2013) 0.85
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11
The structure of haplotype blocks in the human genome. Science (2002) 50.88
Population structure and eigenanalysis. PLoS Genet (2006) 37.21
Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet (1998) 22.90
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Genes mirror geography within Europe. Nature (2008) 14.23
Genotype, haplotype and copy-number variation in worldwide human populations. Nature (2008) 12.40
Estimation of individual admixture: analytical and study design considerations. Genet Epidemiol (2005) 11.00
A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet (2004) 10.87
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet (2006) 9.44
Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science (1996) 8.25
Analysis and application of European genetic substructure using 300 K SNP information. PLoS Genet (2008) 6.42
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. Annu Rev Genomics Hum Genet (2008) 6.06
Caucasian genes in American Negroes. Science (1969) 5.72
Case-control studies of association in structured or admixed populations. Theor Popul Biol (2001) 5.46
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet (2005) 5.02
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Genetic analysis of African populations: human evolution and complex disease. Nat Rev Genet (2002) 4.23
Ancestral proportions and admixture dynamics in geographically defined African Americans living in South Carolina. Am J Phys Anthropol (2001) 3.76
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Patterns of human genetic diversity: implications for human evolutionary history and disease. Annu Rev Genomics Hum Genet (2003) 3.40
Implications of biogeography of human populations for 'race' and medicine. Nat Genet (2004) 3.34
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Recent genetic selection in the ancestral admixture of Puerto Ricans. Am J Hum Genet (2007) 2.72
African human diversity, origins and migrations. Curr Opin Genet Dev (2006) 2.68
Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet (2005) 2.41
PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36
SELECTION, GENE MIGRATION AND POLYMORPHIC STABILITY IN A U. S. WHITE AND NEGRO POPULATION. Am J Hum Genet (1963) 2.20
Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set. PLoS Genet (2009) 2.07
Inferring human population sizes, divergence times and rates of gene flow from mitochondrial, X and Y chromosome resequencing data. Genetics (2007) 2.00
Elevated male European and female African contributions to the genomes of African American individuals. Hum Genet (2006) 1.97
Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics. Hum Genet (2008) 1.57
Fine-scaled human genetic structure revealed by SNP microarrays. Genome Res (2009) 1.48
Ethnic differences in cardiovascular drug response: potential contribution of pharmacogenetics. Circulation (2008) 1.44
Shipwrecks and founder effects: divergent demographic histories reflected in Caribbean mtDNA. Am J Phys Anthropol (2005) 1.40
Genetic structure in four West African population groups. BMC Genet (2005) 1.21
Allelic frequencies of host genetic variants influencing susceptibility to HIV-1 infection and disease in South African populations. AIDS (2000) 1.09
Distribution of CCR2-64I and SDF1-3'A alleles and HIV status in 7 ethnic populations of Cameroon. J Acquir Immune Defic Syndr (2005) 0.98
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
The variant call format and VCFtools. Bioinformatics (2011) 25.88
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Genes mirror geography within Europe. Nature (2008) 14.23
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
A global reference for human genetic variation. Nature (2015) 12.85
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Methods for high-density admixture mapping of disease genes. Am J Hum Genet (2004) 12.02
A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet (2004) 10.87
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data. PLoS Genet (2009) 9.16
Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet (2008) 8.92
A common sequence motif associated with recombination hot spots and genome instability in humans. Nat Genet (2008) 8.64
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med (2002) 8.33
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc Natl Acad Sci U S A (2005) 8.10
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science (2009) 7.64
Demographic history and rare allele sharing among human populations. Proc Natl Acad Sci U S A (2011) 7.36
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16
Ascertainment bias in studies of human genome-wide polymorphism. Genome Res (2005) 6.63
Proportionally more deleterious genetic variation in European than in African populations. Nature (2008) 6.61
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. Annu Rev Genomics Hum Genet (2008) 6.06
Simultaneous inference of selection and population growth from patterns of variation in the human genome. Proc Natl Acad Sci U S A (2005) 5.94
Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science (2005) 5.55
Genome-wide association mapping reveals a rich genetic architecture of complex traits in Oryza sativa. Nat Commun (2011) 5.41
Localizing recent adaptive evolution in the human genome. PLoS Genet (2007) 5.11
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet (2007) 5.09
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet (2005) 5.02
BTA, a novel reagent for DNA attachment on glass and efficient generation of solid-phase amplified DNA colonies. Nucleic Acids Res (2006) 4.93
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science (2005) 4.79
Patterns of positive selection in six Mammalian genomes. PLoS Genet (2008) 4.69
A single IGF1 allele is a major determinant of small size in dogs. Science (2007) 4.68
Genomewide SNP variation reveals relationships among landraces and modern varieties of rice. Proc Natl Acad Sci U S A (2009) 4.65
Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication. Nature (2010) 4.64
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
ClinGen--the Clinical Genome Resource. N Engl J Med (2015) 4.45
The functional spectrum of low-frequency coding variation. Genome Biol (2011) 4.42
A Markov chain Monte Carlo approach for joint inference of population structure and inbreeding rates from multilocus genotype data. Genetics (2007) 4.31
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet (2009) 4.11
The beautiful and ethereal neurological exam: an appeal for research. Ann Neurol (2011) 4.10
Classic selective sweeps were rare in recent human evolution. Science (2011) 4.09
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet (2008) 3.93
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet (2009) 3.92
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature (2010) 3.90
Molecular and evolutionary history of melanism in North American gray wolves. Science (2009) 3.87
Genome-wide patterns of nucleotide polymorphism in domesticated rice. PLoS Genet (2007) 3.83
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Hum Genomics (2005) 3.77
Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial. Lancet (2011) 3.76
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet (2007) 3.61
Status of national health research systems in ten countries of the WHO African Region. BMC Health Serv Res (2006) 3.58
The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron (2006) 3.55
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
A simple genetic architecture underlies morphological variation in dogs. PLoS Biol (2010) 3.46
Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet (2012) 3.31
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. Science (2009) 3.29
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS Genet (2011) 3.20
New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing. Nat Commun (2012) 3.18
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet (2006) 3.13
Darwinian and demographic forces affecting human protein coding genes. Genome Res (2009) 3.01
Great ape genetic diversity and population history. Nature (2013) 2.95
Genetic structure and domestication history of the grape. Proc Natl Acad Sci U S A (2011) 2.89
The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet (2008) 2.83
Whole-mtDNA genome sequence analysis of ancient African lineages. Mol Biol Evol (2006) 2.82
Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nat Genet (2012) 2.78
Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. Lancet Neurol (2006) 2.77
Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Res (2009) 2.76