Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer.

PubWeight™: 1.53‹?› | Rank: Top 4%

🔗 View Article (PMC 1838738)

Published in Proc Natl Acad Sci U S A on November 16, 2006

Authors

Eduardo C Salido1, Xiao M Li, Yang Lu, Xia Wang, Alfredo Santana, Namita Roy-Chowdhury, Armando Torres, Larry J Shapiro, Jayanta Roy-Chowdhury

Author Affiliations

1: Unidad Investigación, Hospital Universitario Canarias, University La Laguna, Tenerife 38320, Spain.

Articles citing this

Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1. Proc Natl Acad Sci U S A (2014) 1.56

Enteric oxalate elimination is induced and oxalate is normalized in a mouse model of primary hyperoxaluria following intestinal colonization with Oxalobacter. Am J Physiol Gastrointest Liver Physiol (2010) 1.55

Hydroxyproline metabolism in mouse models of primary hyperoxaluria. Am J Physiol Renal Physiol (2011) 1.49

An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria. J Am Soc Nephrol (2016) 1.49

Oxalobacter formigenes-Derived Bioactive Factors Stimulate Oxalate Transport by Intestinal Epithelial Cells. J Am Soc Nephrol (2016) 1.39

Calcium oxalate crystal deposition in kidneys of hypercalciuric mice with disrupted type IIa sodium-phosphate cotransporter. Am J Physiol Renal Physiol (2008) 0.96

Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1. Mol Ther (2016) 0.95

Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with primary hyperoxaluria type I. Mol Genet Metab (2011) 0.92

Phenotypic correction of a mouse model for primary hyperoxaluria with adeno-associated virus gene transfer. Mol Ther (2010) 0.90

Glycolate Oxidase Is a Safe and Efficient Target for Substrate Reduction Therapy in a Mouse Model of Primary Hyperoxaluria Type I. Mol Ther (2015) 0.90

Genetic basis of renal cellular dysfunction and the formation of kidney stones. Urol Res (2009) 0.90

Next generation sequencing with copy number variant detection expands the phenotypic spectrum of HSD17B4-deficiency. BMC Med Genet (2014) 0.89

Glyoxylate rather than ascorbate is an efficient precursor for oxalate biosynthesis in rice. J Exp Bot (2010) 0.88

AGXT2: a promiscuous aminotransferase. Trends Pharmacol Sci (2014) 0.85

Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase. Biochim Biophys Acta (2015) 0.84

Primary hyperoxaluria: report of an Italian family with clear sex conditioned penetrance. Urol Res (2008) 0.83

An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice. PLoS One (2014) 0.80

Bifidobacterium animalis subsp. lactis decreases urinary oxalate excretion in a mouse model of primary hyperoxaluria. Urolithiasis (2014) 0.78

Primary cultures of renal proximal tubule cells derived from individuals with primary hyperoxaluria. Urol Res (2009) 0.78

Helper-dependent adenoviral vectors for liver-directed gene therapy of primary hyperoxaluria type 1. Gene Ther (2015) 0.76

Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways. PLoS One (2016) 0.75

In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis. Cell Rep (2016) 0.75

Effects of alanine:glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay. Biochim Biophys Acta (2016) 0.75

Pediatrics: Timely diagnosis of primary hyperoxaluria type 1. Nat Rev Nephrol (2009) 0.75

Bone impairment in primary hyperoxaluria: a review. Pediatr Nephrol (2015) 0.75

Iohexol plasma clearance, a simple and reliable method to measure renal function in conscious mice. Pflugers Arch (2016) 0.75

Molecular therapy of primary hyperoxaluria. J Inherit Metab Dis (2017) 0.75

Simplified estimates of ion-activity products of calcium oxalate and calcium phosphate in mouse urine. Urol Res (2011) 0.75

Articles cited by this

Catalase in vitro. Methods Enzymol (1984) 27.79

Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase. Biochem J (1961) 6.63

Kidney stone disease. J Clin Invest (2005) 3.45

Observations on the analysis of ten thousand urinary calculi. J Urol (1962) 2.27

Reproductive and developmental toxicity of ethylene glycol in the mouse. Toxicol Appl Pharmacol (1985) 2.10

Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules. J Am Soc Nephrol (2003) 1.68

Functional synergism between the most common polymorphism in human alanine:glyoxylate aminotransferase and four of the most common disease-causing mutations. J Biol Chem (2000) 1.53

Animal models of kidney stone formation: an analysis. World J Urol (1997) 1.41

Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species. Biochem J (1978) 1.40

Isolation of rat liver hepatocytes. Methods Mol Biol (1997) 1.34

PxF, a prenylated protein of peroxisomes. J Biol Chem (1994) 1.12

Correction of an enzyme trafficking defect in hereditary kidney stone disease in vitro. Biochem J (2003) 1.03

A semiautomated alanine:glyoxylate aminotransferase assay for the tissue diagnosis of primary hyperoxaluria type 1. Ann Clin Biochem (1997) 1.00

Renal physiology of the mouse. Am J Physiol Renal Physiol (2000) 0.99

Effect of sex hormones on oxalate-synthesizing enzymes in male and female rat livers. J Urol (1999) 0.92

Peroxisomal beta-oxidation of branched chain fatty acids in rat liver. Evidence that carnitine palmitoyltransferase I prevents transport of branched chain fatty acids into mitochondria. J Biol Chem (1994) 0.91

Epidemiological risk factors in calcium stone disease. Scand J Urol Nephrol Suppl (1980) 0.89

Flux of the L-serine metabolism in rat liver. The predominant contribution of serine dehydratase. J Biol Chem (1999) 0.88

Experimental oxalate lithiasis produced with ethylene glycol. Invest Urol (1966) 0.85

Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits. J Lipid Res (1996) 0.84

Toxicities of ethylene glycol and ethylene glycol monoethyl ether in Fischer 344/N rats and B6C3F1 mice. Environ Health Perspect (1984) 0.84

Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors. Mol Ther (2002) 0.84

Ion-chromatographic determination of plasma oxalate reexamined. Clin Chem (1993) 0.83

EFFECT OF TESTOSTERONE ON THE GLYCOLIC ACID OXIDASE LEVELS IN MALE AND FEMALE RAT LIVER. Endocrinology (1964) 0.82

Age and sex as factors in oxalic acid excretion in healthy persons and calcium oxalate stone patients. Contrib Nephrol (1987) 0.81

Oxalate nephropathy in a Tibetan spaniel litter. A probable case of primary hyperoxaluria. J Comp Pathol (1990) 0.80

The mouse alanine:glyoxylate aminotransferase gene (Agxt1): cloning, expression, and mapping to chromosome 1. Somat Cell Mol Genet (1999) 0.80

Articles by these authors

The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med (2011) 6.35

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature (2007) 6.10

Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology (2008) 3.99

Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer. J Biomed Opt (2007) 3.04

Sexually transmitted diseases among users of erectile dysfunction drugs: analysis of claims data. Ann Intern Med (2010) 2.93

Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways. J Virol (2007) 2.88

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Oncogene (2003) 2.84

RXLR-mediated entry of Phytophthora sojae effector Avr1b into soybean cells does not require pathogen-encoded machinery. Plant Cell (2008) 2.72

An algorithm that improves speech intelligibility in noise for normal-hearing listeners. J Acoust Soc Am (2009) 2.52

MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways. J Virol (2008) 2.45

B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element. J Biol Chem (2007) 2.44

Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41

Oct4 pseudogenes are transcribed in cancers. Biochem Biophys Res Commun (2005) 2.34

A general strategy for creating "inactive-conformation" abl inhibitors. Chem Biol (2006) 2.27

The Drosophila melanogaster transcriptome by paired-end RNA sequencing. Genome Res (2010) 2.25

Actin filament dynamics are dominated by rapid growth and severing activity in the Arabidopsis cortical array. J Cell Biol (2009) 2.20

Rfx6 directs islet formation and insulin production in mice and humans. Nature (2010) 2.15

Conserved C-terminal motifs required for avirulence and suppression of cell death by Phytophthora sojae effector Avr1b. Plant Cell (2008) 2.15

Pilot study of 68Ga-DOTA-F(ab')2-trastuzumab in patients with breast cancer. Nucl Med Commun (2013) 2.12

Hyperinsulinemia and hyperfiltration in renal transplantation. Transplantation (2009) 2.06

A multicenter study on the effects of lanthanum carbonate (Fosrenol) and calcium carbonate on renal bone disease in dialysis patients. Kidney Int Suppl (2003) 2.04

Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration. Nat Genet (2012) 1.96

Luteolin, a flavonoid with potential for cancer prevention and therapy. Curr Cancer Drug Targets (2008) 1.95

Regulation of cell death and innate immunity by two receptor-like kinases in Arabidopsis. Cell Host Microbe (2009) 1.93

MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein. Nucleic Acids Res (2011) 1.79

Predialysis nephrologic care and a functioning arteriovenous fistula at entry are associated with better survival in incident hemodialysis patients: an observational cohort study. Am J Kidney Dis (2004) 1.74

A novel risk score for mortality in renal transplant recipients beyond the first posttransplant year. Transplantation (2009) 1.72

Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol (2004) 1.72

Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation. Cancer Cell (2010) 1.71

Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia. Neuron (2011) 1.70

The Flo8 transcription factor is essential for hyphal development and virulence in Candida albicans. Mol Biol Cell (2005) 1.70

Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke. J Neurosci (2011) 1.64

A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci U S A (2012) 1.64

Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements. Hum Genet (2013) 1.63

Similar renal decline in diabetic and non-diabetic patients with comparable levels of albuminuria. Nephrol Dial Transplant (2009) 1.63

Epstein-Barr virus growth/latency III program alters cellular microRNA expression. Virology (2008) 1.63

Sensitization of breast cancer cells to radiation by trastuzumab. Mol Cancer Ther (2003) 1.56

Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice. PLoS One (2009) 1.55

A ferroelectric-like structural transition in a metal. Nat Mater (2013) 1.54

Hepatocyte transplantation. J Hepatol (2004) 1.50

Relationship between oxidative stress and embryotoxicity of hydrosalpingeal fluid. Hum Reprod (2002) 1.49

Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat. J Hepatol (2008) 1.47

Stereoselectivity of satropane, a novel tropane analog, on iris muscarinic receptor activation and intraocular hypotension. Acta Pharmacol Sin (2008) 1.42

Hepatitis C seroconversion in methadone maintenance treatment programs in Wuhan, China. Addiction (2015) 1.42

Barriers to the successful treatment of liver disease by hepatocyte transplantation. J Hepatol (2010) 1.41

Overexpression of rice WRKY89 enhances ultraviolet B tolerance and disease resistance in rice plants. Plant Mol Biol (2007) 1.41

Maoecrystal V, cytotoxic diterpenoid with a novel C19 skeleton from Isodon eriocalyx (Dunn.) hara. Org Lett (2004) 1.41

NANOGP8 is a retrogene expressed in cancers. FEBS J (2006) 1.40

Nanowelded carbon-nanotube-based solar microcells. Small (2008) 1.40

SDG714, a histone H3K9 methyltransferase, is involved in Tos17 DNA methylation and transposition in rice. Plant Cell (2007) 1.39

Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq. RNA (2010) 1.39

Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev (2018) 1.39

Manifestations and evolution of Wilson disease in pediatric patients carrying ATP7B mutation L708P. J Pediatr Gastroenterol Nutr (2012) 1.38

(1R,3S,5R,6S)-6-Acet-oxy-3-(4-methyl-phenyl-sulfon-yloxy)tropane. Acta Crystallogr Sect E Struct Rep Online (2008) 1.35

The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression. Oncogene (2005) 1.35

Multipathogen infections in hospitalized children with acute respiratory infections. Virol J (2009) 1.35

Synthesis and antimicrobial evaluation of nitazoxanide-based analogues: identification of selective and broad spectrum activity. ChemMedChem (2010) 1.33

Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells. Carcinogenesis (2007) 1.33

Next-generation sequencing-based molecular diagnosis of a Chinese patient cohort with autosomal recessive retinitis pigmentosa. Invest Ophthalmol Vis Sci (2013) 1.32

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease. J Ethnopharmacol (2012) 1.32

Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant (2012) 1.31

Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells. J Biol Chem (2007) 1.31

Genomic insights into salt adaptation in a desert poplar. Nat Commun (2013) 1.30

Medical Expenditure Measures in the Health and Retirement Study. Forum Health Econ Policy (2011) 1.28

Whole-genome sequencing of the Akata and Mutu Epstein-Barr virus strains. J Virol (2012) 1.26

Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation. Hepatology (2009) 1.23

MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation. J Virol (2010) 1.23

A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. Mol Pharmacol (2007) 1.23

Identification of small-molecule inducers of pancreatic beta-cell expansion. Proc Natl Acad Sci U S A (2009) 1.20

A system-level investigation into the mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for cardiovascular disease treatment. PLoS One (2012) 1.20

Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis. Mol Pharmacol (2009) 1.18

Systematic review of consistency between adherence to cardiovascular or diabetes medication and health literacy in older adults. Ann Pharmacother (2012) 1.18

Requirement of hypoxia-inducible factor-1alpha down-regulation in mediating the antitumor activity of the anti-epidermal growth factor receptor monoclonal antibody cetuximab. Mol Cancer Ther (2008) 1.17

Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection. Hepatology (2002) 1.17

HIV drug resistance and its impact on antiretroviral therapy in Chinese HIV-infected patients. PLoS One (2013) 1.16

Expression of Nanog gene promotes NIH3T3 cell proliferation. Biochem Biophys Res Commun (2005) 1.16

Double-antigen enzyme-linked immunosorbent assay for detection of hepatitis E virus-specific antibodies in human or swine sera. Clin Vaccine Immunol (2008) 1.15

HIV-1 p55Gag encoded in the lysosome-associated membrane protein-1 as a DNA plasmid vaccine chimera is highly expressed, traffics to the major histocompatibility class II compartment, and elicits enhanced immune responses. J Biol Chem (2003) 1.14

TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis. Apoptosis (2007) 1.14

Detection of murine leukemia virus in the Epstein-Barr virus-positive human B-cell line JY, using a computational RNA-Seq-based exogenous agent detection pipeline, PARSES. J Virol (2012) 1.14

Hyphal chain formation in Candida albicans: Cdc28-Hgc1 phosphorylation of Efg1 represses cell separation genes. Mol Cell Biol (2009) 1.13

Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells. J Exp Clin Cancer Res (2010) 1.13

Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin. Mol Cell Neurosci (2008) 1.12

Virologic outcomes of first-line HAART and associated factors among Chinese patients with HIV in three sentinel antiretroviral treatment sites. Trop Med Int Health (2010) 1.12

Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. Proc Natl Acad Sci U S A (2007) 1.11

Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China. AIDS (2013) 1.11

Clinical implications of stem cell gene Oct-4 expression in breast cancer. Ann Surg (2011) 1.10

Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway. PLoS One (2008) 1.10

The Arabidopsis concentration-dependent influx/efflux transporter ABCB4 regulates cellular auxin levels in the root epidermis. Plant J (2011) 1.10

Differential expression of the miR-200 family microRNAs in epithelial and B cells and regulation of Epstein-Barr virus reactivation by the miR-200 family member miR-429. J Virol (2010) 1.08

Hapten synthesis and enzyme-linked immunosorbent assay for phosmet residues: assay optimization and investigation of matrix effects from different food samples. Anal Bioanal Chem (2009) 1.08

Endo-oxacyclizations of polyepoxides: biomimetic synthesis of fused polycyclic ethers. J Org Chem (2002) 1.08

A profile of nonurgent emergency department use in an urban pediatric hospital. Pediatr Emerg Care (2012) 1.07

Roles of autophagy in cetuximab-mediated cancer therapy against EGFR. Autophagy (2010) 1.07