Adrianus M C H van den Nieuwendijk

Author PubWeight™ 10.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol 2006 1.54
2 Ultrasensitive in situ visualization of active glucocerebrosidase molecules. Nat Chem Biol 2010 1.26
3 Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy. Angew Chem Int Ed Engl 2003 1.25
4 Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors. Org Biomol Chem 2007 1.07
5 A cell-permeable inhibitor and activity-based probe for the caspase-like activity of the proteasome. Bioorg Med Chem Lett 2007 0.96
6 Long-range-distance NMR effects in a protein labeled with a lanthanide-DOTA chelate. Chemistry 2007 0.90
7 Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition. Proc Natl Acad Sci U S A 2015 0.90
8 Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites. J Med Chem 2010 0.85
9 Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases. Bioorg Med Chem Lett 2004 0.81
10 Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. J Med Chem 2014 0.76
11 Inhibition of nucleoside transport by new analogues of nitrobenzylthioinosine. Bioorg Med Chem 2003 0.75
12 A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase. J Am Chem Soc 2017 0.75