Published in Chemistry on January 01, 2007
Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes. Chem Rev (2009) 2.94
Paramagnetic labelling of proteins and oligonucleotides for NMR. J Biomol NMR (2009) 1.16
Prospects for lanthanides in structural biology by NMR. J Biomol NMR (2008) 1.01
PCS-based structure determination of protein-protein complexes. J Biomol NMR (2010) 0.92
How reliable are pseudocontact shifts induced in proteins and ligands by mobile paramagnetic metal tags? A modelling study. J Biomol NMR (2013) 0.92
Two-point anchoring of a lanthanide-binding peptide to a target protein enhances the paramagnetic anisotropic effect. J Biomol NMR (2009) 0.88
Mobility of TOAC spin-labelled peptides binding to the Src SH3 domain studied by paramagnetic NMR. J Biomol NMR (2008) 0.84
Convenient method for resolving degeneracies due to symmetry of the magnetic susceptibility tensor and its application to pseudo contact shift-based protein-protein complex structure determination. J Biomol NMR (2012) 0.81
Analysis of the isomer ratios of polymethylated-DOTA complexes and the implications on protein structural studies. Dalton Trans (2016) 0.81
Protein structural studies by paramagnetic solid-state NMR spectroscopy aided by a compact cyclen-type Cu(II) binding tag. J Biomol NMR (2014) 0.80
A systematic study of labelling an α-helix in a protein with a lanthanide using IDA-SH or NTA-SH tags. J Biomol NMR (2012) 0.80
Integral membrane protein structure determination using pseudocontact shifts. J Biomol NMR (2015) 0.78
A minor conformation of a lanthanide tag on adenylate kinase characterized by paramagnetic relaxation dispersion NMR spectroscopy. J Biomol NMR (2015) 0.77
Cys-Ph-TAHA: a lanthanide binding tag for RDC and PCS enhanced protein NMR. J Biomol NMR (2011) 0.77
Gd(iii) and Mn(ii) complexes for dynamic nuclear polarization: small molecular chelate polarizing agents and applications with site-directed spin labeling of proteins. Phys Chem Chem Phys (2016) 0.75
Paramagnetic Ligand Tagging To Identify Protein Binding Sites. J Am Chem Soc (2015) 0.75
Increasing the Chemical-Shift Dispersion of Unstructured Proteins with a Covalent Lanthanide Shift Reagent. Angew Chem Int Ed Engl (2016) 0.75
Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS One (2009) 2.18
Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR. Proc Natl Acad Sci U S A (2006) 1.89
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol (2006) 1.54
Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events. BMC Genomics (2009) 1.52
Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection. Cell Host Microbe (2008) 1.50
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proc Natl Acad Sci U S A (2012) 1.31
Ultrasensitive in situ visualization of active glucocerebrosidase molecules. Nat Chem Biol (2010) 1.26
Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy. Angew Chem Int Ed Engl (2003) 1.25
Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug. J Infect Dis (2012) 1.18
Interactions of the malaria parasite and its mammalian host. Curr Opin Microbiol (2008) 1.11
Increased paramagnetic effect of a lanthanide protein probe by two-point attachment. J Am Chem Soc (2007) 1.09
Design, synthesis, and evaluation of a lanthanide chelating protein probe: CLaNP-5 yields predictable paramagnetic effects independent of environment. J Am Chem Soc (2008) 1.09
Close encounters of the transient kind: protein interactions in the photosynthetic redox chain investigated by NMR spectroscopy. Acc Chem Res (2003) 1.08
Visualization of the encounter ensemble of the transient electron transfer complex of cytochrome c and cytochrome c peroxidase. J Am Chem Soc (2010) 1.08
Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors. Org Biomol Chem (2007) 1.07
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio. PLoS Pathog (2011) 1.06
Dramatic modulation of electron transfer in protein complexes by crosslinking. Nat Struct Biol (2002) 1.06
Dynamics in a pure encounter complex of two proteins studied by solution scattering and paramagnetic NMR spectroscopy. J Am Chem Soc (2008) 1.05
Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A (2013) 1.05
The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography. J Mol Biol (2013) 1.04
Paramagnetic tagging for protein structure and dynamics analysis. Prog Nucl Magn Reson Spectrosc (2010) 1.04
Dynamics in electron transfer protein complexes. FEBS J (2011) 1.03
Peroxidase activity as a tool for studying the folding of c-type cytochromes. Biochemistry (2002) 1.01
Myoglobin and cytochrome b5: a nuclear magnetic resonance study of a highly dynamic protein complex. Biochemistry (2002) 1.00
Inhibitors of protein: geranylgeranyl transferases. Curr Med Chem (2006) 0.99
Transient protein interactions studied by NMR spectroscopy: the case of cytochrome C and adrenodoxin. Biochemistry (2003) 0.98
Genistein-supplemented diet decreases malaria liver infection in mice and constitutes a potential prophylactic strategy. PLoS One (2008) 0.97
A cell-permeable inhibitor and activity-based probe for the caspase-like activity of the proteasome. Bioorg Med Chem Lett (2007) 0.96
Targeting the liver stage of malaria parasites: a yet unmet goal. J Med Chem (2011) 0.96
Mapping the encounter state of a transient protein complex by PRE NMR spectroscopy. J Biomol NMR (2010) 0.95
Transient complexes of redox proteins: structural and dynamic details from NMR studies. J Mol Recognit (2004) 0.95
The orientations of cytochrome c in the highly dynamic complex with cytochrome b5 visualized by NMR and docking using HADDOCK. Protein Sci (2005) 0.94
Double-stranded helical twisted beta-sheet channels in crystals of gramicidin S grown in the presence of trifluoroacetic and hydrochloric acids. Acta Crystallogr D Biol Crystallogr (2007) 0.94
Antimalarial drugs - host targets (re)visited. Biotechnol J (2006) 0.92
Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family. Mol Microbiol (2013) 0.92
Dynamics in the transient complex of plastocyanin-cytochrome f from Prochlorothrix hollandica. J Am Chem Soc (2008) 0.91
A caged lanthanide complex as a paramagnetic shift agent for protein NMR. Chemistry (2004) 0.91
Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle. Antimicrob Agents Chemother (2011) 0.91
A small molecule inhibitor of signal peptide peptidase inhibits Plasmodium development in the liver and decreases malaria severity. PLoS One (2009) 0.90
Structural and biological evaluation of some loloatin C analogues. Bioorg Med Chem (2009) 0.90
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition. Proc Natl Acad Sci U S A (2015) 0.90
Shifting the equilibrium between the encounter state and the specific form of a protein complex by interfacial point mutations. J Am Chem Soc (2010) 0.89
Accurate long-range distance measurements in a doubly spin-labeled protein by a four-pulse, double electron-electron resonance method. Magn Reson Chem (2008) 0.89
High-field (275 GHz) spin-label EPR for high-resolution polarity determination in proteins. J Magn Reson (2006) 0.89
Small-molecule binding sites on proteins established by paramagnetic NMR spectroscopy. J Am Chem Soc (2013) 0.87
A pH-sensitive, colorful, lanthanide-chelating paramagnetic NMR probe. J Am Chem Soc (2012) 0.87
Alkylated sugar amino acids: a new entry toward highly functionalized dipeptide isosters. Org Lett (2004) 0.87
Measurement of a Cu-Cu distance of 26 A by a pulsed EPR method. Angew Chem Int Ed Engl (2003) 0.87
The chemical modification of liposome surfaces via a copper-mediated [3 + 2] azide-alkyne cycloaddition monitored by a colorimetric assay. Chem Commun (Camb) (2006) 0.87
Conformation of pseudoazurin in the 152 kDa electron transfer complex with nitrite reductase determined by paramagnetic NMR. J Mol Biol (2007) 0.87
A solution model of the complex formed by adrenodoxin and adrenodoxin reductase determined by paramagnetic NMR spectroscopy. Biochemistry (2010) 0.87
Different modes of interaction in cyanobacterial complexes of plastocyanin and cytochrome f. Biochemistry (2005) 0.86
Efficient electron transfer in a protein network lacking specific interactions. J Am Chem Soc (2011) 0.86
Binding hot spot in the weak protein complex of physiological redox partners yeast cytochrome C and cytochrome C peroxidase. J Mol Biol (2008) 0.86
The transient complex of poplar plastocyanin with cytochrome f: effects of ionic strength and pH. Biochim Biophys Acta (2004) 0.86
Effect of the protein matrix of cytochrome c in suppressing the inherent peroxidase activity of its heme prosthetic group. Chembiochem (2002) 0.86
Formation of transient protein complexes. Curr Opin Struct Biol (2013) 0.86
Narrowing the conformational space sampled by two-domain proteins with paramagnetic probes in both domains. J Biomol NMR (2011) 0.85
A new type 2 copper cysteinate azurin. Involvement of an engineered exposed cysteine in copper binding through internal rearrangement. J Biol Chem (2002) 0.85
Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites. J Med Chem (2010) 0.85
Biochemical and crystallographic studies of the Met144Ala, Asp92Asn and His254Phe mutants of the nitrite reductase from Alcaligenes xylosoxidans provide insight into the enzyme mechanism. J Mol Biol (2002) 0.85
Mobility of TOAC spin-labelled peptides binding to the Src SH3 domain studied by paramagnetic NMR. J Biomol NMR (2008) 0.84
A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues. Amino Acids (2013) 0.84
A combinatorial approach toward the generation of ambiphilic peptide-based inhibitors of protein:geranylgeranyl transferase-1. J Comb Chem (2005) 0.84
Beta-turn modified gramicidin S analogues containing arylated sugar amino acids display antimicrobial and hemolytic activity comparable to the natural product. J Am Chem Soc (2006) 0.83
Triterpenoids as inhibitors of erythrocytic and liver stages of Plasmodium infections. Bioorg Med Chem (2011) 0.83
Antimitotic herbicides bind to an unidentified site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites. Mol Biochem Parasitol (2013) 0.82
Role of hydrophobic interactions in the encounter complex formation of the plastocyanin and cytochrome f complex revealed by paramagnetic NMR spectroscopy. J Am Chem Soc (2013) 0.82
A two-armed lanthanoid-chelating paramagnetic NMR probe linked to proteins via thioether linkages. Chemistry (2014) 0.82
Synthesis and biological evaluation of novel turn-modified gramicidin S analogues. Bioorg Med Chem (2003) 0.82
A pulsed EPR method to determine distances between paramagnetic centers with strong spectral anisotropy and radicals: the dead-time free RIDME sequence. J Magn Reson (2009) 0.81
N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads. J Med Chem (2013) 0.81
Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy. Antimicrob Agents Chemother (2011) 0.81
Redox-state-dependent complex formation between pseudoazurin and nitrite reductase. J Am Chem Soc (2007) 0.81
Intermolecular dynamics studied by paramagnetic tagging. J Biomol NMR (2009) 0.81
The effect of replacing the axial methionine ligand with a lysine residue in cytochrome c-550 from Paracoccus versutus assessed by X-ray crystallography and unfolding. FEBS J (2005) 0.81
An NMR-based docking model for the physiological transient complex between cytochrome f and cytochrome c6. FEBS Lett (2005) 0.81
A comparison of triazole-forming bioconjugation techniques for constructing comb-shaped peptide-polymer bioconjugates. Macromol Rapid Commun (2010) 0.81
Self-organizing beta-sheet lipopeptide monolayers as template for the mineralization of CaCO3. Angew Chem Int Ed Engl (2006) 0.81
Conformational changes during apoplastocyanin folding observed by photocleavable modification and transient grating. J Am Chem Soc (2006) 0.81
Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases. Bioorg Med Chem Lett (2004) 0.81
Two-dimensional ordered beta-sheet lipopeptide monolayers. J Am Chem Soc (2006) 0.81
Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies. J Med Chem (2011) 0.81
Imidazoquines as antimalarial and antipneumocystis agents. J Med Chem (2009) 0.80
Gold nanoparticle-based fluorescence immunoassay for malaria antigen detection. Anal Bioanal Chem (2011) 0.80
Synthesis and in vitro evaluation of PNA-peptide-DETA conjugates as potential cell penetrating artificial ribonucleases. Bioconjug Chem (2004) 0.80
PARAssign--paramagnetic NMR assignments of protein nuclei on the basis of pseudocontact shifts. J Biomol NMR (2013) 0.80
Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials. J Med Chem (2014) 0.80
The Src SH2 domain interacts dynamically with the focal adhesion kinase binding site as demonstrated by paramagnetic NMR spectroscopy. IUBMB Life (2012) 0.80
Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule. Mol Immunol (2009) 0.80
An ensemble of rapidly interconverting orientations in electrostatic protein-peptide complexes characterized by NMR spectroscopy. Chembiochem (2014) 0.80