Published in J Exp Med on July 01, 1991
Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance. J Clin Invest (2001) 2.26
Repertoire of CD5+ and CD5- cord blood B cells: specificity and expression of VH I and VH III associated idiotopes. Clin Exp Immunol (1992) 0.79
Increased IgA rheumatoid factor and V(H)1 associated cross reactive idiotype expression in patients with Lyme arthritis and neuroborreliosis. Ann Rheum Dis (1999) 0.76
The role of antigen in the selection of the human V3-23 immunoglobulin heavy chain variable region gene. Clin Exp Immunol (2003) 0.76
Loss of a chromosomal region with synteny to human 13q14 occurs in mouse chronic lymphocytic leukemia that originates from early-generated B-1 B cells. Leukemia (2016) 0.76
Analysis of human antitopoisomerase-I idiotypes. J Clin Invest (1993) 0.75
Sequence analysis of immunoglobulin heavy-chain variable region genes from the synovium of a rheumatoid arthritis patient shows little evidence of mutation but diverse CDR3. Immunology (1995) 0.75
Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia. J Exp Med (1982) 3.25
Normal, autoimmune, and malignant CD5+ B cells: the Ly-1 B lineage? Annu Rev Immunol (1988) 2.50
Limiting dilution analysis of Epstein-Barr virus-induced immunoglobulin production by human B cells. J Exp Med (1983) 1.97
Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families. J Immunol (1989) 1.88
A common idiotope on human rheumatoid factors identified by a hybridoma antibody. Mol Immunol (1983) 1.65
High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (1987) 1.35
Restricted light chain subgroup expression on human rheumatoid factor paraproteins determined by monoclonal antibodies. Immunology (1986) 1.12
Antibodies to shared idiotypes as agents for analysis and therapy for human B cell tumors. Blood (1986) 1.05
Expression of antibody V-regions is genetically and developmentally controlled and modulated by the B lymphocyte environment. Int Immunol (1989) 1.04
The antibody repertoire of early human B cells. I. High frequency of autoreactivity and polyreactivity. Scand J Immunol (1990) 1.04
The incidence of a new human cross-reactive idiotype linked to subgroup VHIII heavy chains. Mol Immunol (1990) 1.03
Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity. J Exp Med (1988) 0.98
A highly conserved conformational idiotope on human IgM rheumatoid factor paraproteins of the Wa cross-reactive idiotype family defined by a monoclonal antibody. Rheumatol Int (1990) 0.94
Structural characterization of human monoclonal cold agglutinins: evidence for a distinct primary sequence-defined VH4 idiotype. Eur J Immunol (1990) 0.91
Monoclonal antibodies to restricted and cross-reactive idiotopes on monoclonal rheumatoid factors and their recognition of idiotope-positive cells. Eur J Immunol (1987) 0.90
Monoclonal antibody against a cross-reactive idiotypic determinant found on human autoantibodies with anti-I and -i specificities. Mol Immunol (1983) 0.87
Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood (1999) 11.50
Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG. J Exp Med (1977) 9.57
Evaluation of monoclonal antibodies having specificity for human IgG sub-classes: results of an IUIS/WHO collaborative study. Immunol Lett (1985) 4.23
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. J Exp Med (1987) 3.82
Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. J Mol Biol (2003) 3.25
Monoclonal antibodies (McAbs) to determinants on human gamma chains: properties of antibodies showing subclass restriction or subclass specificity. Immunology (1982) 2.79
Morphological and histochemical analyses of two human T-cell subpopulations bearing receptors for IgM or IgG. J Exp Med (1978) 2.58
Fc-receptor heterogeneity of human suppressor T cells. J Immunol (1978) 2.37
Age-related changes in human blood lymphocyte subpopulations. J Pediatr (1992) 2.17
Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome. Nat Genet (1999) 1.88
Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis. Ann Rheum Dis (1989) 1.85
DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma. Nat Med (1998) 1.83
Imbalances in T cell subpopulations associated with immunodeficiency and autoimmune syndromes. Eur J Immunol (1977) 1.74
Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells. Blood (1997) 1.73
Properties of monoclonal antibodies to human immunoglobulin kappa and lambda chains. Immunology (1981) 1.65
Ontogeny of B cells in the chicken. I. Sequential development of clonal diversity in the bursa. J Exp Med (1976) 1.63
Antibody to a molecularly-defined antigen confined to a tumour cell surface. Nature (1975) 1.61
Extracellular idiotypic immunoglobulin arising from human leukemic B lymphocytes. J Exp Med (1980) 1.57
Aspects of the molecular structure of IgG subclasses. Monogr Allergy (1986) 1.56
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype. J Immunol (1991) 1.56
Effect of in utero growth retardation on lung function at follow-up of prematurely born infants. Eur Respir J (2004) 1.55
Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction. Nat Struct Biol (1997) 1.53
VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities. J Immunol (1992) 1.52
Localisation of the monocyte-binding region on human immunoglobulin G. Mol Immunol (1986) 1.52
The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms. Mol Immunol (2001) 1.51
Role of oligosaccharide residues of IgG1-Fc in Fc gamma RIIb binding. J Biol Chem (2001) 1.48
Immunogenic and antigenic epitopes of immunoglobulins. XVII--Monoclonal antibodies reactive with common and restricted idiotopes to the heavy chain of human rheumatoid factors. Rheumatol Int (1986) 1.47
Expression of VHIII-associated cross-reactive idiotype on human B lymphocytes. Association with staphylococcal protein A binding and Staphylococcus aureus Cowan I stimulation. J Immunol (1991) 1.44
Relationship between the papain sensitivity of human gammaG immunoglobulins and their heavy chain subclass. Nature (1968) 1.44
Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes. J Exp Med (1976) 1.41
IgG4 as the predominant autoantibody in sera from patients with active state of pemphigus vulgaris. J Eur Acad Dermatol Venereol (2004) 1.41
Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteins. J Immunol (1988) 1.39
Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans. J Clin Invest (1988) 1.38
Differential glycosylation of polyclonal IgG, IgG-Fc and IgG-Fab isolated from the sera of patients with ANCA-associated systemic vasculitis. Biochim Biophys Acta (2005) 1.38
IgG subclass distribution of autoantibodies to DNA and to nuclear ribonucleoproteins in autoimmune diseases. Immunology (1984) 1.37
Suppression of B lymphocyte differentiation by newborn T lymphocytes with an Fc receptor for IgM. Clin Exp Immunol (1978) 1.36
Surface immunoglobulin of guinea-pig leukaemic lymphocytes. Immunology (1975) 1.36
Induction of tumor necrosis factor alpha production by adhered human monocytes: a key role for Fcgamma receptor type IIIa in rheumatoid arthritis. Arthritis Rheum (2000) 1.34
Immunoglobulin V genes and CD38 expression in CLL. Blood (2000) 1.30
Studies of generation of B-cell diversity in mouse, man, and chicken. Cold Spring Harb Symp Quant Biol (1977) 1.30
Idiotypic networks and their possible exploitation for manipulation of the immune response. Lancet (1981) 1.29
Immunogenetic analysis of the immune response to pneumococcal polysaccharide. Eur J Immunol (2000) 1.28
Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc gamma receptor I and influence the synthesis of its oligosaccharide chains. J Immunol (1996) 1.26
Human Fc gamma RI and Fc gamma RII interact with distinct but overlapping sites on human IgG. J Immunol (1991) 1.25
Preliminary experience in treating lymphocytic leukaemia with antibody to immunoglobulin idiotypes on the cell surfaces. Br J Cancer (1980) 1.25
Idiotypic determinants on the surface immunoglobulin of neoplastic lymphocytes: a therapeutic target. Fed Proc (1977) 1.25
Use of the ELISA to screen for anti-thymocyte and anti-beta 2-microglobulin antibodies in leprosy and SLE. Immunology (1980) 1.22
Aglycosylation of human IgG1 and IgG3 monoclonal antibodies can eliminate recognition by human cells expressing Fc gamma RI and/or Fc gamma RII receptors. Biochem J (1989) 1.22
The separation of human serum IgG into subclass fractions by immunoaffinity chromatography and assessment of specific antibody activity. J Immunol Methods (1984) 1.21
Some effects on leukaemic B lymphocytes of antibodies to defined regions of their surface immunoglobulin. Immunology (1977) 1.21
Reduced B-cell galactosyltransferase activity in rheumatoid arthritis. Lancet (1987) 1.21
Protein-polysaccharide complexes secreted by the calf tracheal epithelium in vitro. Biochem J (1969) 1.19
Antibody activity in the presence of urea or guanidine. Biochim Biophys Acta (1967) 1.19
The monocyte binding domain(s) on human immunoglobulin G. Mol Immunol (1984) 1.19
Recurrent respiratory symptoms in the first year of life following preterm delivery. J Perinat Med (1990) 1.18
Immunogenic and antigenic epitopes of immunoglobulins. X: Monoclonal antibodies specific for human IgA, the IgA1 and IgA2 subclasses and an nA2m(2) iso-allotypic epitope. Vox Sang (1985) 1.18
Autoimmunity and idiotypes. Lancet (1984) 1.17
Immunogenic and antigenic epitopes of immunoglobulins--V. Reactivity of a panel of monoclonal antibodies with sub-fragments of human Fc gamma and abnormal paraproteins having deletions. Mol Immunol (1983) 1.15
CD5 expression in human B-cell populations. Immunol Today (1999) 1.15
Studies of human IgD myeloma proteins. Proteolytic digestion patterns. Immunochemistry (1977) 1.14
Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fc gamma receptor. Mol Immunol (1992) 1.14
A minority of patients with rheumatoid arthritis show a dominant rearrangement of T-cell receptor beta chain genes in synovial lymphocytes. Scand J Immunol (1987) 1.13
Optimizing the P300-based brain-computer interface: current status, limitations and future directions. J Neural Eng (2011) 1.13
Comparative structural study of the N-linked oligosaccharides of human normal and pathological immunoglobulin G. Biochemistry (1987) 1.12
Histamine suppression of lymphocyte activation. Clin Exp Immunol (1980) 1.12
Restricted light chain subgroup expression on human rheumatoid factor paraproteins determined by monoclonal antibodies. Immunology (1986) 1.12
The solution conformations of the subclasses of human IgG deduced from sedimentation and small angle X-ray scattering studies. Mol Immunol (1987) 1.12
Taking immunogenicity assessment of therapeutic proteins to the next level. Biologicals (2011) 1.12
Engagement of CD40 lowers the threshold for activation of resting B cells via antigen receptor. Eur J Immunol (1993) 1.11
The prevalence and distribution of macrophages bearing Fc gamma R I, Fc gamma R II, and Fc gamma R III in synovium. Scand J Rheumatol (1990) 1.11
Anti-neutrophil cytoplasm antibody IgG subclasses in Wegener's granulomatosis: a possible pathogenic role for the IgG4 subclass. Clin Exp Immunol (2004) 1.11
Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity. Blood (1995) 1.11
Structural studies of human IgD paraproteins. Immunol Rev (1977) 1.10
Characteristics and function of Fc receptors on human lymphocytes. Immunology (1982) 1.09
Monoclonal antibodies to the idiotypic determinants of a human IgG paraprotein: evidence for complexity of the anti-idiotype response. Clin Exp Immunol (1982) 1.09
Immunogenic and antigenic epitopes of immunoglobulins. II. Antigenic differences between secreted and membrane IgG demonstrated using monoclonal antibodies. J Immunol (1982) 1.09
Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells. Oncogene (2006) 1.08
Pathogenic autoantibodies in the NZB mouse are specific for erythrocyte band 3 protein. Eur J Immunol (1993) 1.08
Anti-idiotypic mechanisms involved in suppression of a mouse B cell lymphoma, BCL1. J Immunol (1987) 1.08
Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus. J Autoimmun (1992) 1.08
The I binding specificity of human VH 4-34 (VH 4-21) encoded antibodies is determined by both VH framework region 1 and complementarity determining region 3. J Mol Biol (1996) 1.08
Differential rates of somatic hypermutation in V(H) genes among subsets of chronic lymphocytic leukemia defined by chromosomal abnormalities. Blood (1997) 1.07
Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment. J Exp Med (1993) 1.07
Analysis of immunoglobulin E VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events. Immunology (1999) 1.06
Characterization of CD3+ CD4- CD8- (double negative) T cells in patients with systemic lupus erythematosus: production of IL-4. Lupus (2002) 1.06
Characterization of CD3+ CD4- CD8- (double negative) T cells in patients with systemic lupus erythematosus: activation markers. Lupus (2002) 1.05
Antibodies to shared idiotypes as agents for analysis and therapy for human B cell tumors. Blood (1986) 1.05
Hypogalactosylation of serum IgG in patients with ANCA-associated systemic vasculitis. Clin Exp Immunol (2002) 1.05
Human antibodies elicited by a pneumococcal vaccine express idiotypic determinants indicative of V(H)3 gene segment usage. J Infect Dis (1998) 1.04
The incidence of a new human cross-reactive idiotype linked to subgroup VHIII heavy chains. Mol Immunol (1990) 1.03
CD5-expressing B lymphocytes in the blood and salivary glands of patients with primary Sjögren's syndrome. J Autoimmun (1988) 1.03
Specificity of plasma cells in the rheumatoid synovium. I. Immunoglobulin class of antiglobulin-producing cells. Scand J Immunol (1984) 1.03
In vitro cytotoxicity of a new epoxy resin root canal sealer. J Endod (2000) 1.03
Immunogenic and antigenic epitopes of immunoglobulins binding of human monoclonal anti-D antibodies to FcRI on the monocyte-like U937 cell line. Vox Sang (1988) 1.02
A gamma Bence-Jones protein in guinea pigs. Biochem J (1975) 1.02
Analysis of soluble HLA class II antigenic material in patients with immunological diseases using monoclonal antibodies. J Immunol Methods (1986) 1.02