Published in Bioorg Med Chem on November 10, 2006
Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4. J Med Chem (2011) 0.85
Alkylation of prohibitin by cyclohexylphenyl-chloroethyl urea on an aspartyl residue is associated with cell cycle G(1) arrest in B16 cells. Br J Pharmacol (2007) 0.79
Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA (2009) 13.00
Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis (2004) 6.65
Hypothermia therapy after traumatic brain injury in children. N Engl J Med (2008) 6.10
Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study. Lancet (2003) 5.40
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell (2002) 4.52
Phagosomes are competent organelles for antigen cross-presentation. Nature (2003) 3.97
Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat Immunol (2009) 2.80
Risk factors of acute renal failure in critically ill children: A prospective descriptive epidemiological study. Pediatr Crit Care Med (2007) 2.60
Cumulative influence of organ dysfunctions and septic state on mortality of critically ill children. Am J Respir Crit Care Med (2004) 2.56
Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med (2011) 2.35
Parental involvement in treatment decisions regarding their critically ill child: a comparative study of France and Quebec. Pediatr Crit Care Med (2007) 2.22
The phagosomal proteome in interferon-gamma-activated macrophages. Immunity (2009) 1.95
Modes of death in pediatrics: differences in the ethical approach in neonatal and pediatric patients. J Pediatr (2013) 1.81
Procalcitonin and C-reactive protein as markers of bacterial infection in critically ill children at onset of systemic inflammatory response syndrome. Pediatr Crit Care Med (2008) 1.80
Targeted temperature management in critical care: a report and recommendations from five professional societies. Crit Care Med (2011) 1.72
Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum. Pediatr Crit Care Med (2011) 1.64
Phagocytosis: at the crossroads of innate and adaptive immunity. Annu Rev Cell Dev Biol (2005) 1.63
Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods. Pediatr Crit Care Med (2003) 1.62
Evaluation of the pediatric risk of admission score in a pediatric emergency department. Ann Emerg Med (2003) 1.58
Determinants of red blood cell transfusions in a pediatric critical care unit: a prospective, descriptive epidemiological study. Crit Care Med (2005) 1.57
Survey on transfusion practices of pediatric intensivists. Pediatr Crit Care Med (2002) 1.55
The endosomal proteome of macrophage and dendritic cells. Proteomics (2011) 1.52
Children with chronic conditions in pediatric intensive care units located in predominantly French-speaking regions: Prevalence and implications on rehabilitation care need and utilization. Crit Care Med (2009) 1.52
Clinical equipoise regarding glycemic control: a survey of pediatric intensivist perceptions. Pediatr Crit Care Med (2013) 1.52
Problems with co-funding in Canada. Science (2005) 1.48
Respiratory Dysfunction Associated With RBC Transfusion in Critically Ill Children: A Prospective Cohort Study. Pediatr Crit Care Med (2015) 1.46
Paediatric logistic organ dysfunction (PELOD) score. Lancet (2006) 1.45
Clinical Outcomes Associated With RBC Transfusions in Critically Ill Children: A 1-Year Prospective Study. Pediatr Crit Care Med (2015) 1.44
PICU mortality: is it better 9 to 5? Pediatr Crit Care Med (2005) 1.42
Survey on stated transfusion practices in PICUs*. Pediatr Crit Care Med (2014) 1.42
Cardiac arrhythmias associated with severe traumatic brain injury and hypothermia therapy. Pediatr Crit Care Med (2010) 1.42
Human invariant chain isoform p35 restores thymic selection and antigen presentation in CD74-deficient mice. Immunol Cell Biol (2012) 1.40
Organelle proteomics: looking at less to see more. Trends Cell Biol (2003) 1.30
Anemia, blood loss, and blood transfusions in North American children in the intensive care unit. Am J Respir Crit Care Med (2008) 1.25
Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion (2010) 1.25
The pediatric multiple organ dysfunction syndrome. Pediatr Crit Care Med (2009) 1.24
Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. Crit Care (2010) 1.23
Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo. J Immunol (2006) 1.22
Hypothermia therapy after pediatric cardiac arrest. Circulation (2009) 1.19
Trafficking of Leishmania donovani promastigotes in non-lytic compartments in neutrophils enables the subsequent transfer of parasites to macrophages. Cell Microbiol (2007) 1.18
PELOD-2: an update of the PEdiatric logistic organ dysfunction score. Crit Care Med (2013) 1.16
Modulation of the phagosome proteome by interferon-gamma. Mol Cell Proteomics (2007) 1.15
Inspiratory muscle unloading by neurally adjusted ventilatory assist during maximal inspiratory efforts in healthy subjects. Chest (2007) 1.15
Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking. Cell Microbiol (2002) 1.14
Survey of transfusion policies at US and Canadian children's hospitals in 2008 and 2009. Transfusion (2010) 1.14
Prolonged neural expiratory time induced by mechanical ventilation in infants. Pediatr Res (2004) 1.10
Incidence of deep vein thrombosis related to peripherally inserted central catheters in children and adolescents. CMAJ (2007) 1.08
Molecular characterization of the evolution of phagosomes. Mol Syst Biol (2010) 1.08
Alternative pathways for MHC class I presentation: a new function for autophagy. Cell Mol Life Sci (2011) 1.08
Daily estimation of the severity of multiple organ dysfunction syndrome in critically ill children. CMAJ (2010) 1.07
Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis. Crit Care Med (2010) 1.05
A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Proteomics (2013) 1.04
Leishmania evades host immunity by inhibiting antigen cross-presentation through direct cleavage of the SNARE VAMP8. Cell Host Microbe (2013) 1.02
In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity on CYP-450 (Part 2). Bioorg Med Chem (2007) 0.98
LRPPRC mutations cause a phenotypically distinct form of Leigh syndrome with cytochrome c oxidase deficiency. J Med Genet (2011) 0.98
Remodeling of endosomes during lysosome biogenesis involves 'kiss and run' fusion events regulated by rab5. J Cell Sci (2003) 0.97
Randomized clinical trials in pediatric critical care: Rarely done but desperately needed. Pediatr Crit Care Med (2002) 0.97
Combined enzymatic and data mining approaches for comprehensive phosphoproteome analyses: application to cell signaling events of interferon-gamma-stimulated macrophages. Mol Cell Proteomics (2007) 0.97
Leishmania donovani lipophosphoglycan disrupts phagosome microdomains in J774 macrophages. Cell Microbiol (2005) 0.97
Proteomic analysis reveals a role for protein kinase C-alpha in phagosome maturation. Biochem Biophys Res Commun (2004) 0.96
Gamma-secretase is a functional component of phagosomes. J Biol Chem (2005) 0.96
Acute transfusion reactions in the pediatric intensive care unit. Transfusion (2006) 0.95
Diaphragm electrical activity during expiration in mechanically ventilated infants. Pediatr Res (2006) 0.95
Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cells. Transfusion (2009) 0.95
Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proc Natl Acad Sci U S A (2012) 0.95
Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study. Crit Care (2010) 0.94
Massive cell vacuolization induced by organic amines such as procainamide. J Pharmacol Exp Ther (2004) 0.93
Cell biology through proteomics--ad astra per alia porci. Trends Cell Biol (2010) 0.93
Subcellular localization of iron and heme metabolism related proteins at early stages of erythrophagocytosis. PLoS One (2012) 0.92
Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies. Crit Care (2012) 0.92
Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Mol Cell Proteomics (2012) 0.91
A new generation of N-aryl-N'-(1-alkyl-2-chloroethyl)ureas as microtubule disrupters: synthesis, antiproliferative activity, and beta-tubulin alkylation kinetics. J Med Chem (2003) 0.90
Quantitative proteomics reveals the induction of mitophagy in tumor necrosis factor-α-activated (TNFα) macrophages. Mol Cell Proteomics (2013) 0.90
Risk factors associated with increased length of mechanical ventilation in children. Pediatr Crit Care Med (2012) 0.89
Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: a class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance. Cancer Res (2004) 0.88
Developmental outcome after a single episode of status epilepticus. Epilepsy Behav (2011) 0.87
Red blood cell transfusion threshold in postsurgical pediatric intensive care patients: a randomized clinical trial. Ann Surg (2010) 0.86
Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells. J Pharmacol Exp Ther (2006) 0.85
Struggling to do what is right for the child: pediatric life-support decisions among physicians and nurses in France and Quebec. J Child Health Care (2012) 0.85
Nuclear membrane-derived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection. Autophagy (2009) 0.85
Noninvasive or invasive hemoglobin measurement? Crit Care Med (2012) 0.85
The role of comparative effectiveness research in transfusion medicine clinical trials: proceedings of a National Heart, Lung, and Blood Institute workshop. Transfusion (2012) 0.85
Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4. J Med Chem (2011) 0.85
Excess of veno-occlusive disease in a randomized clinical trial on a higher trigger for red blood cell transfusion after bone marrow transplantation: a canadian blood and marrow transplant group trial. Biol Blood Marrow Transplant (2012) 0.85
Glutathione peroxidase-1 expression enhances recovery of human breast carcinoma cells from hyperoxic cell cycle arrest. Free Radic Biol Med (2002) 0.84
Subcellular phosphoproteomics. Mass Spectrom Rev (2010) 0.84
Proteomics analysis of herpes simplex virus type 1-infected cells reveals dynamic changes of viral protein expression, ubiquitylation, and phosphorylation. J Proteome Res (2013) 0.84
Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical and surgical critically ill patients: a prospective observational cohort study. Crit Care (2011) 0.84
The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial. J Pediatr (2003) 0.84
Xylylated dimers of putrescine and polyamines: influence of the polyamine backbone on spermidine transport inhibition. Bioorg Med Chem Lett (2003) 0.83
ER-mediated phagocytosis: myth or reality? J Leukoc Biol (2005) 0.83
The moral experience of parents regarding life-support decisions for their critically-ill children: a preliminary study in France. J Child Health Care (2006) 0.83
Women's decision making about the use of natural health products at menopause: a needs assessment and patient decision aid. J Altern Complement Med (2007) 0.83
A facile synthesis of C(2)-symmetric 17 beta-estradiol dimers. Bioorg Med Chem Lett (2003) 0.83
Red blood cell transfusion in critically ill children (CME). Transfusion (2013) 0.83