Published in J Struct Funct Genomics on November 22, 2006
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Overcoming barriers to membrane protein structure determination. Nat Biotechnol (2011) 2.49
Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis. Proc Natl Acad Sci U S A (2006) 2.07
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
Arthritogenic monoclonal antibodies from K/BxN mice. J Exp Med (2002) 1.94
A common evolutionary origin for tailed-bacteriophage functional modules and bacterial machineries. Microbiol Mol Biol Rev (2011) 1.92
Receptor-binding protein of Lactococcus lactis phages: identification and characterization of the saccharide receptor-binding site. J Bacteriol (2006) 1.85
Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses. Nat Struct Mol Biol (2005) 1.84
Tubulin is an inherent component of mitochondrial membranes that interacts with the voltage-dependent anion channel. J Biol Chem (2002) 1.80
Structural biology of type VI secretion systems. Philos Trans R Soc Lond B Biol Sci (2012) 1.72
A medium-throughput crystallization approach. Acta Crystallogr D Biol Crystallogr (2002) 1.72
Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains. J Virol (2006) 1.70
Cytidine deaminase residual activity in serum is a predictive marker of early severe toxicities in adults after gemcitabine-based chemotherapies. J Clin Oncol (2009) 1.69
The structure of cbb3 cytochrome oxidase provides insights into proton pumping. Science (2010) 1.68
A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme. Nature (2003) 1.66
DICER1 mutations in embryonal rhabdomyosarcomas from children with and without familial PPB-tumor predisposition syndrome. Pediatr Blood Cancer (2011) 1.62
The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world. Proc Natl Acad Sci U S A (2004) 1.61
Modular structure of the receptor binding proteins of Lactococcus lactis phages. The RBP structure of the temperate phage TP901-1. J Biol Chem (2006) 1.57
Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment. Oncotarget (2011) 1.54
Medium-scale structural genomics: strategies for protein expression and crystallization. Acc Chem Res (2003) 1.53
Structure of lactococcal phage p2 baseplate and its mechanism of activation. Proc Natl Acad Sci U S A (2010) 1.53
Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology. J Biol Chem (2002) 1.51
Crystallisation of membrane proteins mediated by antibody fragments. Curr Opin Struct Biol (2002) 1.50
Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity. J Biol Chem (2004) 1.46
Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen. Protein Sci (2006) 1.46
Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar. PLoS Pathog (2011) 1.44
Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein. J Biol Chem (2003) 1.43
Structural aspects of sexual attraction and chemical communication in insects. Trends Biochem Sci (2004) 1.37
Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism. Proc Natl Acad Sci U S A (2012) 1.37
A topological model of the baseplate of lactococcal phage Tuc2009. J Biol Chem (2007) 1.36
The crystal structure of a cockroach pheromone-binding protein suggests a new ligand binding and release mechanism. J Biol Chem (2003) 1.36
Clinicopathologic prognostic factors in childhood atypical teratoid and rhabdoid tumor of the central nervous system: a multicenter study. Cancer (2011) 1.34
Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc Natl Acad Sci U S A (2006) 1.33
Direct observation of tiers in the energy landscape of a chromoprotein: a single-molecule study. Proc Natl Acad Sci U S A (2003) 1.33
Automated expression and solubility screening of His-tagged proteins in 96-well format. Anal Biochem (2005) 1.32
The crystal structure of the pyoverdine outer membrane receptor FpvA from Pseudomonas aeruginosa at 3.6 angstroms resolution. J Mol Biol (2005) 1.32
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient. J Mol Biol (2007) 1.31
LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis. EMBO J (2006) 1.31
Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa. J Mol Biol (2005) 1.26
The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. Proc Natl Acad Sci U S A (2009) 1.26
Dynamic water networks in cytochrome C oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations. Biophys J (2004) 1.26
Reduction of cytochrome c oxidase by a second electron leads to proton translocation. Nature (2002) 1.25
Direct in vivo screening of intrabody libraries constructed on a highly stable single-chain framework. J Biol Chem (2002) 1.25
Frequent hSNF5/INI1 germline mutations in patients with rhabdoid tumor. Clin Cancer Res (2011) 1.24
High-throughput automated refolding screening of inclusion bodies. Protein Sci (2004) 1.23
Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: implications for cancer treatment. Curr Cancer Drug Targets (2007) 1.23
Biophysical properties of camelid V(HH) domains compared to those of human V(H)3 domains. Biochemistry (2002) 1.22
Solution and electron microscopy characterization of lactococcal phage baseplates expressed in Escherichia coli. J Struct Biol (2010) 1.22
Crystal structure of the receptor-binding protein head domain from Lactococcus lactis phage bIL170. J Virol (2006) 1.22
Comparative analysis and "expression space" coverage of the production of prokaryotic membrane proteins for structural genomics. Protein Sci (2006) 1.21
Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis. A novel carboxyl esterase structurally related to the HSL family. Eur J Biochem (2004) 1.20
High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: new insights into the active site and the proton transfer pathways. Biochim Biophys Acta (2009) 1.20
Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme. J Mol Biol (2004) 1.20
Single-molecule study of the electronic couplings in a circular array of molecules: light-harvesting-2 complex from Rhodospirillum molischianum. Phys Rev Lett (2003) 1.20
Neurocognitive function after radiotherapy for paediatric brain tumours. Nat Rev Neurol (2012) 1.19
Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode. J Biol Chem (2009) 1.19
Crystal structure of bacteriophage SPP1 distal tail protein (gp19.1): a baseplate hub paradigm in gram-positive infecting phages. J Biol Chem (2010) 1.16
Sulfur single-wavelength anomalous diffraction crystal structure of a pheromone-binding protein from the honeybee Apis mellifera L. J Biol Chem (2003) 1.14
Moth chemosensory protein exhibits drastic conformational changes and cooperativity on ligand binding. Proc Natl Acad Sci U S A (2003) 1.13
Structure and molecular assignment of lactococcal phage TP901-1 baseplate. J Biol Chem (2010) 1.13
All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc Natl Acad Sci U S A (2002) 1.12
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Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis. Structure (2007) 1.10
Novel mutations in TTC37 associated with tricho-hepato-enteric syndrome. Hum Mutat (2011) 1.10
High-throughput protein expression screening and purification in Escherichia coli. Methods (2011) 1.09
Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems. J Biol Chem (2012) 1.08
Multiconformation continuum electrostatics analysis of the NhaA Na+/H+ antiporter of Escherichia coli with functional implications. Proc Natl Acad Sci U S A (2006) 1.08
The MAM (meprin/A5-protein/PTPmu) domain is a homophilic binding site promoting the lateral dimerization of receptor-like protein-tyrosine phosphatase mu. J Biol Chem (2004) 1.08
Investigation of the relationship between lactococcal host cell wall polysaccharide genotype and 936 phage receptor binding protein phylogeny. Appl Environ Microbiol (2013) 1.07
Deciphering the Xcp Pseudomonas aeruginosa type II secretion machinery through multiple interactions with substrates. J Biol Chem (2011) 1.07
Intractable diarrhea with "phenotypic anomalies" and tricho-hepato-enteric syndrome: two names for the same disorder. Am J Med Genet A (2007) 1.06
Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors. Protein Expr Purif (2003) 1.06
There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 1.06
An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp. Proc Natl Acad Sci U S A (2004) 1.06
Crystal structure of nitrous oxide reductase from Paracoccus denitrificans at 1.6 A resolution. Biochem J (2003) 1.06
A new structure-based classification of sulfide:quinone oxidoreductases. Proteins (2010) 1.05
A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate. J Mol Biol (2008) 1.05
TssK is a trimeric cytoplasmic protein interacting with components of both phage-like and membrane anchoring complexes of the type VI secretion system. J Biol Chem (2013) 1.05
X-ray structure and ligand binding study of a moth chemosensory protein. J Biol Chem (2002) 1.05
Crystal structure of ORF12 from Lactococcus lactis phage p2 identifies a tape measure protein chaperone. J Bacteriol (2008) 1.05
Children treated with metronomic chemotherapy in a low-income country: METRO-MALI-01. J Pediatr Hematol Oncol (2011) 1.05
The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity. J Mol Biol (2004) 1.05
Effect of rickettsial toxin VapC on its eukaryotic host. PLoS One (2011) 1.04
A hyperthermostable D-ribose-5-phosphate isomerase from Pyrococcus horikoshii characterization and three-dimensional structure. Structure (2002) 1.04
Perforin-dependent apoptosis functionally compensates Fas deficiency in activation-induced cell death of human T lymphocytes. Blood (2007) 1.04
Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis. FEBS Lett (2005) 1.04
Structures of the glycosylphosphatidylinositol membrane anchors from Aspergillus fumigatus membrane proteins. Glycobiology (2002) 1.04