Published in Mol Biol Cell on November 22, 2006
Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nat Cell Biol (2007) 2.23
Regulation of actin cytoskeleton dynamics by Arf-family GTPases. Trends Cell Biol (2008) 1.58
ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway. Cancer Res (2009) 1.40
Cdc42 localization and cell polarity depend on membrane traffic. J Cell Biol (2010) 1.38
ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. J Biol Chem (2008) 1.27
Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation. BMC Cell Biol (2007) 1.19
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion. J Biol Chem (2008) 1.12
Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets. Biochem Pharmacol (2011) 1.03
New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration. Cell Adh Migr (2009) 1.01
Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling. Mol Biol Cell (2007) 0.95
Arf6 coordinates actin assembly through the WAVE complex, a mechanism usurped by Salmonella to invade host cells. Proc Natl Acad Sci U S A (2013) 0.93
GEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cells. PLoS One (2012) 0.90
Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor. J Biol Chem (2012) 0.89
The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family. J Biol Chem (2011) 0.88
ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion. Mol Biol Cell (2013) 0.88
The neuronal Arf GAP centaurin alpha1 modulates dendritic differentiation. J Cell Sci (2007) 0.87
ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology. J Biol Chem (2013) 0.85
Vascular endothelial growth factor receptor-2 activates ADP-ribosylation factor 1 to promote endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells. J Biol Chem (2010) 0.84
The guanine nucleotide exchange protein for ADP-ribosylation factor 6, ARF-GEP100/BRAG2, regulates phagocytosis of monocytic phagocytes in an ARF6-dependent process. J Biol Chem (2010) 0.84
The GTPase ARF6 Controls ROS Production to Mediate Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation. PLoS One (2016) 0.84
The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells. J Biol Chem (2014) 0.82
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Dynamin- and Rab5-dependent endocytosis is required to prevent Drosophila photoreceptor degeneration. J Cell Sci (2011) 0.80
The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors. Cancer Biol Ther (2015) 0.79
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ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. PLoS One (2017) 0.75
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Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D. J Cell Biol (2001) 3.49
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An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells. Nat Cell Biol (2005) 3.44
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ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA. Mol Cell Biol (2000) 1.91
beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J Biol Chem (2004) 1.75
ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting. Mol Cell Biol (1999) 1.73
beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis. J Biol Chem (2001) 1.63
The GIT/PIX complex: an oligomeric assembly of GIT family ARF GTPase-activating proteins and PIX family Rac1/Cdc42 guanine nucleotide exchange factors. Cell Signal (2004) 1.56
p95-APP1 links membrane transport to Rac-mediated reorganization of actin. Nat Cell Biol (2000) 1.53
Modulation of Rac1 and ARF6 activation during epithelial cell scattering. J Biol Chem (2003) 1.44
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G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton. Mol Biol Cell (2005) 1.36
ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth. Mol Biol Cell (2003) 1.31
G protein-coupled receptor endocytosis in ADP-ribosylation factor 6-depleted cells. J Biol Chem (2004) 1.17
Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. Mol Cell Proteomics (2006) 1.05
c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrin- mediated internalization. Mol Endocrinol (2004) 1.04
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Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science (2003) 3.27
Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration. Curr Biol (2006) 2.03
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. Proc Natl Acad Sci U S A (2008) 1.93
Mammalian Scribble forms a tight complex with the betaPIX exchange factor. Curr Biol (2004) 1.89
Phospholipase D1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage. J Biol Chem (2007) 1.69
SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions. Mol Biol Cell (2007) 1.62
The GIT/PIX complex: an oligomeric assembly of GIT family ARF GTPase-activating proteins and PIX family Rac1/Cdc42 guanine nucleotide exchange factors. Cell Signal (2004) 1.56
Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs. J Cell Biol (2003) 1.47
G protein-coupled receptors stimulation and the control of cell migration. Cell Signal (2009) 1.46
Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability. J Biol Chem (2004) 1.40
G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton. Mol Biol Cell (2005) 1.36
Annexin 2 promotes the formation of lipid microdomains required for calcium-regulated exocytosis of dense-core vesicles. Mol Biol Cell (2005) 1.32
G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Mol Cell Biol (2004) 1.32
ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. J Biol Chem (2008) 1.27
Coupling actin and membrane dynamics during calcium-regulated exocytosis: a role for Rho and ARF GTPases. Biochim Biophys Acta (2004) 1.20
Dynamics and function of phospholipase D and phosphatidic acid during phagocytosis. Traffic (2006) 1.19
Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Mol Cell Biol (2006) 1.19
G protein-coupled receptor endocytosis in ADP-ribosylation factor 6-depleted cells. J Biol Chem (2004) 1.17
Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis. Mol Biol Cell (2013) 1.16
Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway. EMBO J (2005) 1.10
Role of phosphoinositide signaling in the control of insulin exocytosis. Mol Endocrinol (2005) 1.09
X-linked mental retardation: focus on synaptic function and plasticity. J Neurochem (2009) 1.08
The RhoGAP RGA-2 and LET-502/ROCK achieve a balance of actomyosin-dependent forces in C. elegans epidermis to control morphogenesis. Development (2007) 1.08
Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs. Sci Signal (2012) 1.07
Functional implication of neuronal calcium sensor-1 and phosphoinositol 4-kinase-beta interaction in regulated exocytosis of PC12 cells. J Biol Chem (2006) 1.07
Exocytosis: the chromaffin cell as a model system. Ann N Y Acad Sci (2002) 1.04
Purification, crystallization and preliminary X-ray diffraction studies of a complex between G protein-coupled receptor kinase 2 and Gbeta1gamma2. Acta Crystallogr D Biol Crystallogr (2003) 1.04
IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation. Proc Natl Acad Sci U S A (2007) 1.03
Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2. Biochemistry (2002) 1.01
ARF6 regulates the synthesis of fusogenic lipids for calcium-regulated exocytosis in neuroendocrine cells. J Biol Chem (2009) 1.01
Phospholipase D in calcium-regulated exocytosis: lessons from chromaffin cells. Biochim Biophys Acta (2009) 1.00
PIKfyve negatively regulates exocytosis in neurosecretory cells. J Biol Chem (2007) 0.99
betaPIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells. J Cell Sci (2009) 0.98
Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins. EMBO J (2011) 0.97
Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells. Blood (2008) 0.97
The V-ATPase membrane domain is a sensor of granular pH that controls the exocytotic machinery. J Cell Biol (2013) 0.97
ARF6 activation by Galpha q signaling: Galpha q forms molecular complexes with ARNO and ARF6. Cell Signal (2006) 0.95
ADP-ribosylation factor 6 regulates mammalian myoblast fusion through phospholipase D1 and phosphatidylinositol 4,5-bisphosphate signaling pathways. Mol Biol Cell (2010) 0.94
Genetically encoded probes for phosphatidic acid. Methods Cell Biol (2012) 0.94
Ephrin B1 maintains apical adhesion of neural progenitors. Development (2013) 0.92
Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway. Philos Trans R Soc Lond B Biol Sci (2013) 0.92
ARF6 regulates angiotensin II type 1 receptor endocytosis by controlling the recruitment of AP-2 and clathrin. Cell Signal (2007) 0.91
A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway. J Biol Chem (2010) 0.91
Lipids in Regulated Exocytosis: What are They Doing? Front Endocrinol (Lausanne) (2013) 0.90
Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity. Cell Signal (2008) 0.89
Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1. J Biol Chem (2006) 0.89
Diacylglycerol stimulates acrosomal exocytosis by feeding into a PKC- and PLD1-dependent positive loop that continuously supplies phosphatidylinositol 4,5-bisphosphate. Biochim Biophys Acta (2012) 0.88
ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion. Mol Biol Cell (2013) 0.88
The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1. Proc Natl Acad Sci U S A (2008) 0.88
Ral isoforms are implicated in Fc gamma R-mediated phagocytosis: activation of phospholipase D by RalA. J Immunol (2010) 0.87
ARF1 controls Rac1 signaling to regulate migration of MDA-MB-231 invasive breast cancer cells. Cell Signal (2013) 0.87
Live-cell imaging of phosphatidic acid dynamics in pollen tubes visualized by Spo20p-derived biosensor. New Phytol (2014) 0.86
The synaptic ribbon is a site of phosphatidic acid generation in ribbon synapses. J Neurosci (2011) 0.85
Regulation of exocytosis in adrenal chromaffin cells: focus on ARF and Rho GTPases. Cell Signal (2003) 0.85
Vascular endothelial growth factor receptor-2 activates ADP-ribosylation factor 1 to promote endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells. J Biol Chem (2010) 0.84
G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade. Cell Signal (2013) 0.83
IL1RAPL1 controls inhibitory networks during cerebellar development in mice. Eur J Neurosci (2009) 0.83
In vitro controllability of the MagScrew total artificial heart system. ASAIO J (2002) 0.82
The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells. J Biol Chem (2014) 0.82
HIV-1 Tat protein inhibits neurosecretion by binding to phosphatidylinositol 4,5-bisphosphate. J Cell Sci (2012) 0.81
The GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells. PLoS One (2009) 0.81
The Coffin-Lowry syndrome-associated protein RSK2 regulates neurite outgrowth through phosphorylation of phospholipase D1 (PLD1) and synthesis of phosphatidic acid. J Neurosci (2013) 0.80
Rab11 is phosphorylated by classical and novel protein kinase C isoenzymes upon sustained phorbol ester activation. Biol Cell (2012) 0.80
In vivo studies of the MagScrew total artificial heart in calves. ASAIO J (2002) 0.80
Distinct structural features of G protein-coupled receptor kinase 5 (GRK5) regulate its nuclear localization and DNA-binding ability. PLoS One (2013) 0.80
Targeting the prostaglandin F2α receptor for preventing preterm labor with azapeptide tocolytics. J Med Chem (2011) 0.77
[ARF proteins: molecular switches controlling tumour proliferation and metastasis]. Med Sci (Paris) (2009) 0.77
The Coffin-Lowry syndrome-associated protein RSK2 controls neuroendocrine secretion through the regulation of phospholipase D1 at the exocytotic sites. Ann N Y Acad Sci (2009) 0.76
The long coiled-coil protein NECC2 is associated to caveolae and modulates NGF/TrkA signaling in PC12 cells [corrected]. PLoS One (2013) 0.76
[The GIT-PIX protein complex: a hub to ARF and Rac/Cdc42 GTPases]. Med Sci (Paris) (2005) 0.76
Correction: Ultra-low fouling alkylimidazolium modified surfaces for the detection of HER2 in breast cancer cell lysates. Analyst (2017) 0.75
Investigation of the active turn geometry for the labour delaying activity of indolizidinone and azapeptide modulators of the prostaglandin F2α receptor. Org Biomol Chem (2015) 0.75
Arterial stiffness induced by carotid calcification leads to cerebral gliosis mediated by oxidative stress. J Hypertens (2017) 0.75
Ultra-low fouling methylimidazolium modified surfaces for the detection of HER2 in breast cancer cell lysates. Analyst (2017) 0.75